Search clinical trials for: [11C]MK-4232

Total 3963 results

Merck Sharp & Dohme LLC

Completed

Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)

Migraine
Yale University

Terminated

FAAH Availability in Psychiatric Disorders: A PET Study

Post Traumatic Stress Disorder | Psychosis | Alcohol Use Disorder

United States
Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Merck Sharp & Dohme LLC

Completed

[11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001)

Alzheimer's Disease
Johnson & Johnson Vision Care, Inc.

Completed

Evaluating Soft Contact Lens Prototypes for Myopia Control

Visual Acuity

China
Inovio Pharmaceuticals
GeneOne Life Science, Inc.; Defense Advanced Research Projects Agency

Completed

Open-Label Study of INO-4212 With or Without INO-9012, Administered IM or ID Followed by Electroporation in Healthy Volunteers

Ebola Vaccine

United States
Celgene

Completed

Positron Emission Tomography (PET) Imaging Study to Evaluate Enzyme Availability in the Central Nervous System Before and After CC-97489 Administration in Healthy Participants

Healthy Volunteers

Belgium
Wendell Yap, MD
University of Kansas Medical Center

No longer available

Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan

Prostate Cancer

United States
Jose Gutierrez, MD, MPH

Enrolling by invitation

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

Dementia | Alzheimer Disease

United States
José A. Luchsinger
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Albert... and other collaborators

Terminated

Brain Imaging in the Diabetes Prevention Program Outcomes Study (DPPOS-Brain)

Alzheimer Disease

United States
National Institute of Mental Health (NIMH)

Completed

Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112

Healthy

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Clinical Trials Consortium

Recruiting

Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

Dementia | Alzheimer Disease | Down Syndrome

United States, Spain, United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand 11C-MK-3168 and the Blocking of the Retention of the Ligand in the Human Brain by JNJ-42165279

Healthy

Belgium
MetiMedi Pharmaceuticals

Unknown

OMT-111 for Terminal Stage Solid Tumors

Breast Cancer | Pancreatic Cancer | Lung Cancer

Vietnam
Emory University

Completed

Norepinephrine Transporter Availability in PTSD

Posttraumatic Stress Disorder

United States
University of North Carolina, Chapel Hill
Boston Children's Hospital; Medical College of Wisconsin; National Football League

Enrolling by invitation

NFL LONG Prospective Study

Concussion, Brain

United States
Weill Medical College of Cornell University

Completed

Carbon-11 Butanol: Whole Body Radiochemical and Radiation Safety ([11C]Butanol)

Neuro-Degenerative Disease

United States
Columbia University

Recruiting

Exploratory Evaluation of [11C]MPC6827

Neurodegenerative Diseases | Amyotrophic Lateral Sclerosis | Alzheimer Disease

United States
Columbia University

Completed

Imaging Inflammation in Alzheimer's Disease With 11C-ER176

Alzheimer Disease

United States
Avid Radiopharmaceuticals
General Electric; American College of Radiology Imaging Network

Completed

Ability Of ([18F]-AV-45) PET Scan to Distinguish Alzheimer's Disease Subjects From Cognitively Normal Individuals

Alzheimer's Disease

United States
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
Yale University
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Novel in Vivo Synaptic Imaging in Experienced Meditators (app311_med)

Behavior, Health

United States
St. Jude Children's Research Hospital

Available

Expanded Access [11C] Methionine PET Imaging

Head and Neck Neoplasms | Central Nervous System Tumor

United States
Thallion Pharmaceuticals

Completed

Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma

Carcinoma, Renal Cell

France
Hoffmann-La Roche

Completed

Evaluation of [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948 as Tracers for Positron Emission Tomography (PET) Imaging of Tau in Healthy and Alzheimer's Disease (AD) Participants

Alzheimer's Disease, Healthy Volunteer

United States
Thallion Pharmaceuticals

Terminated

Efficacy Study of TLN-232 in Patients With Recurring Metastatic Melanoma

Melanoma

United States, Canada
Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Completed

Dosimetry of [11C]CHDI-180R and [11C]CHDI-626.

Huntington Disease

Belgium
National Institute of Mental Health (NIMH)

Terminated

PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand

Dementia

United States
Forma Therapeutics, Inc.
Medpace, Inc.

Completed

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Healthy Volunteers | Sickle Cell Disease

United States
Forma Therapeutics, Inc.
Emory University

Not yet recruiting

Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Disease

Sickle Cell Disease

United States
Columbia University
National Institute on Aging (NIA)

Recruiting

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

Alzheimer Disease

United States
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
Yale University
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Recruiting

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy (ART)

Healthy | HIV Dementia | HIV Associated Neurocognitive Disorder | HIV Encephalitis

United States
National Institute on Alcohol Abuse and Alcoholism...

Recruiting

Brain Dopaminergic Signaling in Opioid Use Disorders

Normal Physiology | Opioid Use Disorders

United States
Walter Reed Army Institute of Research (WRAIR)
National Institute of Mental Health (NIMH); National Intrepid Center of Excellence

Recruiting

CNS Correlates of Extended Sleep Restriction

Sleep Restriction

United States
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
University of Pennsylvania

Terminated

11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation

Mild Cognitive Impairment

United States
University of Pennsylvania
University of Miami; Biogen; University of Kansas

Terminated

Multimodal Imaging Outcome Measures for ALS (Image ALS)

ALS

United States
Johns Hopkins University
National Institute on Aging (NIA)

Completed

PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers

Alzheimer's Disease

United States
Synektik S.A.
European Commission

Completed

A Phase I Study of a Novel Tracer for Positron Emission Tomography "PET" Myocardial Perfusion Imaging "MPI"

Coronary Artery Disease
Mayo Clinic
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Long-term Effects of COVID-19

COVID-19 | SAR-CoV-2

United States
Merck Sharp & Dohme LLC

Terminated

A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)

Neoplasms Malignant
Centre Hospitalier St Anne
Roche Pharma AG

Not yet recruiting

Impact of Microglial Activation on Synaptic Density in Alzheimer's Disease (GliSyn)

Alzheimer Disease

France
Vanderbilt University Medical Center

Active, not recruiting

Quantitative Imaging of Brain Glymphatic Function in Humans

Parkinson Disease

United States
Merck Sharp & Dohme LLC

Completed

A Research Study to Test Safety, Tolerability, and Immunogenicity of a Recombinant Hepatitis B Vaccine Manufactured With an Upgrade to the Production Process (V232-054)

Hepatitis B Infection
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [11C]AZD2995 and [11C]AZD2184, Candidate PET Ligands for β Amyloid (PET)

Alzheimer´s Disease

Sweden
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

SV2 PET Imaging With [11C]APP311 (SV2)

Healthy | Cannabis Use Disorder | Schizophrenia and Other Psychotic Disorders

United States
Washington University School of Medicine

Enrolling by invitation

CS1P1 PET Studies of Neuroinflammation in Parkinson Disease

Parkinson Disease

United States
National Institute of Mental Health (NIMH)

Terminated

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

HIV Infections | Healthy | AIDS Dementia Complex | AIDS-Related Dementia Complex | HIV-Associated Cognitive Motor Complex | HIV-Dementia | AIDS Encephalopathy

United States
H. Lundbeck A/S

Completed

A Positron Emission Tomography (PET) Study to Examine the Brain Binding Properties of a Novel Radioactive Compound [11C]-PXT012253 in Healthy Subjects

Parkinson Disease

Sweden

Search clinical trials for: [11C]MK-4232

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