Search clinical trials for: [14C] NKTR-118

Total 4140 results

IRCCS San Raffaele

Recruiting

Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children

Pediatric Brain Tumor

Italy
Cliniques universitaires Saint-Luc- Université...

Completed

Fresh Frozen Plasma and Plasmalyte ® for Priming Cardiopulmonary Bypass in Infants and Children

Congenital Heart Disease

Belgium
Stempeutics Research Pvt Ltd
Stempeutics Research Malaysia SDN BHD

Completed

Allogeneic Mesenchymal Stem Cells for Osteoarthritis

Osteoarthritis of Knee Joint

Malaysia
Stempeutics Research Pvt Ltd
Stempeutics Research Malaysia SDN BHD

Withdrawn

Ex Vivo Cultured Adult Allogenic MSCs in Ischemic Cerebral Stroke

Stroke

Malaysia
University of California, San Francisco

Completed

Davunetide (AL-108) in Predicted Tauopathies - Pilot Study

Progressive Supranuclear Palsy | Corticobasal Degeneration Syndrome | Progressive Nonfluent Aphasia | Predicted Tauopathies, Including | Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17

United States
Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers

Healthy
Sunnybrook Health Sciences Centre

Withdrawn

Study to Evaluate the Feasibility of 13-C Pyruvate Imaging in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy (LABC)

Breast Cancer

Canada
Insmed Incorporated

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants

Healthy Volunteers

United States
Kirilys Therapeutics, Inc.

Completed

Phase 1 Study to Evaluate ASN002 Absorption, Metabolism, and Excretion of [14C] Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteer

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
GlaxoSmithKline

Completed

Radiolabel Study In Healthy Volunteers For Insomnia-Targeting Drug

Sleep Initiation and Maintenance Disorders

United Kingdom
Pfizer

Completed

Phase I Study to Determine the Absorption, Distribution, Metabolism and Excretion of Esreboxetine (ADME)

Healthy

United States
JS InnoPharm, LLC

Recruiting

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

Melanoma | NSCLC | Solid Tumor

China
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

Evaluate the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Homozygous Familial Hypercholesterolemia
Antengene Discovery Limited

Recruiting

A Study of ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies (ATRIUM)

Advanced Solid Tumors | Hematological Malignancies

Australia
Aprea Therapeutics

Recruiting

Study Of ATRN-119 In Patients With Advanced Solid Tumors (ABOYA-119)

Advanced Solid Tumor

United States
Arvinas Androgen Receptor, Inc.

Active, not recruiting

Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Prostate Cancer Metastatic

United States
ML Bio Solutions, Inc.

Active, not recruiting

Study of BBP-418 in Patients With LGMD2I

LGMD2I

United States
Magenta Therapeutics, Inc.

Terminated

Study of MGTA-117 in Patients With Adult Acute Myeloid Leukemia (AML) and Myelodysplasia-Excess Blasts (MDS-EB)

Acute Myeloid Leukemia | Myelodysplasia

United States
Ascentage Pharma Group Inc.

Completed

APG-115 in Patients With Advanced Solid Tumors or Lymphomas (APG-115)

Patients With Advanced Solid Tumor or Lymphoma

United States
CytomX Therapeutics

Withdrawn

PROCLAIM-CX-188: A Trial to Find Safe and Active Doses of an Investigational Drug CX-188 for Patients With Solid Tumors

Solid Tumor, Adult

United States
Jazz Pharmaceuticals

Completed

"A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA"

Obstructive Sleep Apnea | Narcolepsy

United States, France, Canada, Germany, Netherlands, Finland
Biocad

Completed

Study of BCD-115 in Women With ER(+) HER2(-) Local Advanced and Metastatic Breast Cancer

Breast Cancer

Russian Federation
argenx

Completed

A Phase 1b Study of ARGX-111 in Patients With Advanced Cancer.

Cancer

Belgium
BioMarin Pharmaceutical

Terminated

A Study to Evaluate the Long-Term Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

Morquio A Syndrome | MPS IV A | Mucopolysaccharidosis IVA

United Kingdom
Advanced Cancer Therapeutics

Unknown

Phase 1 Safety Study of ACT-PFK-158, 2HCl in Patients With Advanced Solid Malignancies

Cancer

United States
Vascular Biogenics Ltd. operating as VBL Therapeutics

Unknown

A Phase I Study to Assess the Safety and Distribution of VB-111 in Patients With Advanced Metastatic Cancer

Advanced and/or Metastatic Solid Organ Cancer

United States
BioMarin Pharmaceutical

Completed

A Study to Evaluate the Safety, Tolerability and Efficacy of BMN 110 in Subjects With Mucopolysaccharidosis IVA

MPS IV A

United Kingdom
Mast Therapeutics, Inc.
CytRx

Completed

Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease

Sickle Cell Anemia
GenVec

Completed

Study of AdGVPEDF.11D in Neovascular Age-related Macular Degeneration (AMD)

Macular Degeneration

United States
TargeGen

Completed

Safety of TG100-115 for Heart Attack Treated With Angioplasty

Myocardial Infarction

United States
Ospedale Regionale di Locarno

Completed

Dialysis Membranes and Hemodynamic Tolerance

Dialysis Membranes and Hemodynamic Tolerance

Switzerland
Oregon State University
National Institute of Environmental Health Sciences (NIEHS); Pacific Northwest... and other collaborators

Completed

Ultralow Dose PAH Binary Mixture Study

Environmental Exposure

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
PegBio Co., Ltd.
Tigermed Consulting Co., Ltd

Completed

Dose-finding of PB-119 Administered Subcutaneously Once-weekly Versus Placebo in Drug-naïve T2DM Subjects

Type 2 Diabetes Mellitus

China
National Institute of Neurological Disorders and...

Recruiting

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Parkinson's Disease | Multiple System Atrophy | Autonomic Failure

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal Disease

Metastatic Head and Neck Squamous Cell Carcinoma | Metastatic Squamous Cell Carcinoma in Cervical Lymph Node

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery

Glioblastoma

United States
Oregon State University
National Institute of Environmental Health Sciences (NIEHS); Pacific Northwest... and other collaborators

Completed

Benzo[a]Pyrene Ultralow Dose-Response Study

Environmental Exposure

United States
Sunshine Lake Pharma Co., Ltd.

Completed

Study on the Body Mass Balance and Biotransformation of [14C]-HEC585

Healthy Volunteer

China
MedDay Pharmaceuticals SA
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Eli Lilly and Company

Completed

A Study of LY2940680 in Healthy Participants

Healthy Volunteers

United States
Eli Lilly and Company

Terminated

A Study of [14C]-LY3023703 in Healthy Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

A Single Dose Study to Determine the Excretion, Balance and Metabolic Disposition of Radiolabelled GW642444.

Pulmonary Disease, Chronic Obstructive

Netherlands
Amicus Therapeutics

Completed

A Study to Assess the Absorption, Metabolism and Excretion of Migalastat Hydrochloride (AT1001-014)

Fabry Disease
Eli Lilly and Company

Completed

A Study of LY2157299 Monohydrate in Healthy Volunteers

Healthy Volunteers

United States
AstraZeneca

Terminated

Open-Label Absorption, Distribution, Metabolism, Excretion (ADME) and Pharmacokinetics (PK) Following a Single Oral Dose of AZD1236 in Healthy Male Subjects

Healthy

United Kingdom
Kazia Therapeutics Limited
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Healthy

United Kingdom
Aristea Therapeutics, Inc.

Completed

A Study of the ADME of [14C]RIST4721 in Healthy Male Subjects

Healthy | ADME

United Kingdom

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