Search clinical trials for: [14C]CS0159

Total 2771 results

Susan Chang
National Cancer Institute (NCI)

Active, not recruiting

Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma

Glioblastoma Multiforme (GBM)

United States
Saisei Pharma

Completed

Trial Efficacy of Saisei Pharma Dietary Supplements MAF Capsules, 148 mg and M Capsules, 148 mg in Hospitalized COVID-19 Patients (SaiseiCovUKR)

Covid19

Ukraine
University of California, San Francisco
GE Healthcare

Completed

Hyperpolarized Pyruvate Injection in Subjects With Prostate Cancer

Prostate Cancer

United States
University of Aarhus

Completed

Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

Denmark
Washington University School of Medicine

Recruiting

Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1

Alzheimer Disease

United States
Davidzon, Guido, M.D.
Weston Havens Foundation

Recruiting

Imaging Synapses With [11C] UCB-J in the Human Brain

Schizophrenia

United States
Biocad

Completed

Phase I Study of BCD-145 (Anti-CTLA-4) in Patients With Unresectable/Metastatic Melanoma

Melanoma

Russian Federation
MedImmune LLC
Amgen

Completed

A Study to Evaluate the Pharmacokinetics of MEDI9929 (AMG 157) in Adolescents With Mild to Moderate Asthma

Asthma

Poland
GlaxoSmithKline

Completed

Phase 0 Microdose Study

Autoimmune Diseases

United States
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C Pyruvate MRI for Early Immune Evaluation in Cervical Cancer Patients at Baseline and CCRT Therapy

Cervical Cancer

Taiwan
University of Florida

Completed

13C-Pyruvate Breath Test (PBT)

Healthy

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Carbon-14-Labelled [14C] LOXO-305 (Pirtobrutinib) in Healthy Male Participants

Healthy

United States
Sanofi

Completed

A Study to Evaluate Absolute Bioavailability, Absorption, Metabolism, and Excretion of Genz-112638 in Healthy Male Participants

Gaucher's Disease Type I
Ardea Biosciences, Inc.

Completed

Bioavailability of Lesinurad and Intravenous [14C]Lesinurad

Healthy

United States
Peking Union Medical College Hospital

Recruiting

[18F]Florbetazine ([18F]92) for Beta Amyloid PET Imaging in Alzheimer's Disease

Alzheimer's Disease

China
Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Not yet recruiting

Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.

Huntington Disease

Belgium
SecuraBio

Completed

A Long-term, Continued Treatment and Follow-up Study in Participants With Hematologic Malignancies Treated With Duvelisib (IPI-145)

Hematologic Malignancy

United States, Italy
Vivozon Pharmaceutical Inc.

Completed

Phase 3 Efficacy and Safety of VVZ-149 Injections for Postoperative Pain Following Laparoscopic Colectomy

Pain, Postoperative | Acute Pain

Korea, Republic of
Fudan University

Active, not recruiting

Accuracy of VABB Elite 10G Versus BARD 14G CNB

Breast Cancer

China
Vivozon, Inc.

Completed

Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-Operative Pain Following Abdominoplasty

Pain, Postoperative

United States
Christine Elizabeth Edmonds

Withdrawn

Imaging With [11C]Martinostat in Breast Cancer

Breast Cancer

United States
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY

Healthy Volunteers

United States
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Completed

Phase I Dose Escalation Study of the Safety and Pharmacokinetics of ME-143 Single Agent for Refractory Solid Tumors

Solid Tumors

United States
H. Lundbeck A/S

Completed

A Study Investigating Tablet Formulations of Lu AF11167 in Healthy Subjects

Healthy

United Kingdom
BeiGene

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-BGB-3111 in Healthy Males

Healthy Volunteers

United States
Robert Flavell, MD, PhD
Bristol-Myers Squibb; U.S. Army Medical Research Acquisition Activity

Recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer

Prostate Cancer | Localized Prostate Carcinoma

United States
United Therapeutics

Completed

Effect of Food on the Pharmacokinetics of Oral Treprostinil

Pulmonary Arterial Hypertension | Hypertension, Pulmonary

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]- BIBW 2992 MA2 in Healthy Male Volunteers

Healthy
Johns Hopkins University
Precision Molecular

Terminated

Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS

Amyotrophic Lateral Sclerosis

United States
United Therapeutics

Completed

Efficacy and Safety of Oral UT-15C Tablets to Treat Pulmonary Arterial Hypertension (FREEDOM-C2)

Pulmonary Hypertension

United States, Canada, Germany, Spain, Belgium, Sweden, Israel, France, Italy, Netherlands, Portugal, United Kingdom
Vivozon, Inc.

Completed

Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Postoperative Pain Following Bunionectomy

Pain, Postoperative

United States
Massachusetts General Hospital
Genentech, Inc.

Unknown

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

Multiple Sclerosis
Wayne State University

Terminated

Mobile Phone Application Versus Handheld Device for Fetal Vibroacoustic Stimulation

Pregnancy

United States
M.D. Anderson Cancer Center
Infinity Pharmaceuticals, Inc.

Withdrawn

IPI-145 in Relapsed Refractory Acute Lymphoblastic Leukemia (ALL)

Leukemia
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid (PET)

Alzheimer's Disease

Sweden
Hoffmann-La Roche

Completed

Bioavailability Study of Vemurafenib in Participants With BRAF^V600 Mutation-Positive Malignancies

Malignant Melanoma, Cancer

Hungary
Wuhan Union Hospital, China

Recruiting

The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis

PET/MR | Systemic Amyloidosis

China
University of Texas Southwestern Medical Center

Enrolling by invitation

Imaging of Traumatic Brain Injury Metabolism Using Hyperpolarized Carbon-13 Pyruvate (HPTBI)

Traumatic Brain Injury

United States
GE Healthcare
Medpace, Inc.; i3 Statprobe

Completed

Single Dose Safety, Tolerance and Pharmacokinetic Study in Healthy Volunteers Undergoing Contrast-enhanced Abdominal Computed Tomography (CT)

Healthy

United States
University of Texas Southwestern Medical Center

Enrolling by invitation

Using Hyperpolarized [1-13C]Pyruvate to Detect Cardiotoxicity (HPCardiotox)

Breast Neoplasms

United States
Stanford University

Active, not recruiting

Reliability of [18F]-FTC-146 Brain Uptake in Healthy Controls (rSIG)

Healthy Controls

United States
University of Cologne
Boehringer Ingelheim; ZKS Köln

Completed

SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Infusion

SARS-CoV-2 Infection

Germany
Iovance Biotherapeutics, Inc.

Active, not recruiting

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma (LN-144)

Metastatic Melanoma

United States, Spain, Germany, United Kingdom, France, Hungary, Italy, Switzerland
PepsiCo Global R&D

Completed

Dose Response Effect of Chia Seeds on Subjective Appetite and Glycemic Response

Nutrition, Healthy

Canada
University of Cologne
Boehringer Ingelheim; ZKS Köln

Completed

SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Inhalation

SARS-CoV-2 Infection

Germany
AstraZeneca

Completed

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Brain Distribution of [11C]AZ12807110 and AZD5213

Sweden
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
Johns Hopkins University
United States Department of Defense

Not yet recruiting

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

ALS
Rutgers, The State University of New Jersey
Ludwig Institute for Cancer Research

Not yet recruiting

Investigating the Metabolic Pathways in Hormone Receptor Positive/HER2 Negative Breast Cancer

Breast Cancer

United States
Merus N.V.
Incyte Corporation

Recruiting

A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies

Advanced Cancer | Solid Tumor, Adult | B-cell Lymphoma, Adult

United States, Spain, Belgium, Netherlands

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