Search clinical trials for: [14C]SHR1459

Total 2761 results

Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Study to Evaluate the Mass Balance and Biotransformation of [14C]SHR1459 in Healthy Adult Male Volunteers

Healthy Adult Male Volunteers

China
Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Reistone Biopharma Company Limited

Active, not recruiting

Evaluate the Efficacy and Safety of SHR1459 Tablets in Patients With Primary Membranous Nephropathy

Primary Membranous Nephropathy

China
Reistone Biopharma Company Limited

Completed

An Open Label Study of the Effects of SHR1459 in NMOSDs Patients

Neuromyelitis Optica Spectrum Disorders

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety, Tolerability and PK/PD of SHR1459 in Healthy Volunteers

Healthy Volunteers

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Bioavailability Study of SHR1459 on Healthy Chinese Volunteers

Healthy Adult Subjects

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Tolerance and Pharmacokinetics of SHR1459 in Patients With Recurrent Replased/Refractory Mature B Cell Neoplasmstumor

Mature B Cell Neoplasms

China
Vivozon, Inc.

Completed

Absorption, Metabolism, Excretion, and Mass Balance Study of [14C]-VVZ-149 in Healthy Adult Male Subjects

Healthy Adult Male

United States
Rachel Lieberman

Terminated

Capsular Tension Rings in Intraocular Lens Rotation

Cataract | Ophthalmoplegia | Ophthalmologic Complication

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Food Effect Study of SHR1459 on Healthy Chinese Adult Subjects

Healthy Adult Subjects

China
Jiangsu HengRui Medicine Co., Ltd.

Terminated

SHR9549 in ER Positive HER2 Negative Advanced Breast Cancer

ER+ HER2- Advanced Breast Cancer

China
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Trial of SHR1258 in Patients With Biliary Tract Cancer

Biliary Tract Cancer
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
Shanghai Hengrui Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

China
Hengrui Therapeutics, Inc.

Unknown

Phase I Study of Pyrotinib in Patients With HER2-positive Solid Tumors

Breast Cancer | Gastric Cancer | NSCLC | Solid Tumors

United States
Laekna Limited

Completed

Human Mass Balance and Biotransformation Study of [14C]Afuresertib

Healthy Volunteer

China
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Healthy Participants

Netherlands
Indivior Inc.

Completed

Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants

Opioid Use Disorder

United States
Biogen
Denali Therapeutics Inc.

Completed

A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects

Healthy Volunteers

United States
Tianjin Medical University Second Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

The Basket Study of Pyrotinib Maleate for HER2-Postive Solid Tumor

Solid Tumor | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein Overexpression

China
Reata, a wholly owned subsidiary of Biogen

Completed

A Human AME Study for Omaveloxolone

Healthy Male Subjects

United States
Cyclerion Therapeutics

Completed

A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers

Healthy Volunteers

United States
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Healthy Participants

Healthy Participants

United Kingdom
Athira Pharma
Alturas Analytics, Inc.; Labcorp Drug Development Inc

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)

Healthy Volunteers

United States
Biogen
Denali Therapeutics Inc.

Completed

A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects

Healthy Volunteers

United States
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Healthy

United States
H. Lundbeck A/S

Completed

Study Investigating the Safety and Tolerability of Lu AF88434 in Healthy Young Men

Healthy

Netherlands
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Recruiting

The Mass Balance Study of [14C]JT001

Healthy Subjects

China
Impact Therapeutics, Inc.

Not yet recruiting

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

Solid Tumor
Biogen

Completed

A Study to Look at How a Single Oral Dose of Carbon-14-Labelled [14C] BIIB091 Moves Through and is Processed by the Body in Healthy Male Participants (Mass Balance)

Healthy Volunteer

United States
Rivus Pharmaceuticals, Inc.

Completed

A Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-HU6

Healthy

United States
Guangdong Raynovent Biotech Co., Ltd

Completed

Mass Balance Study of [14C]RAY1216 in Healthy Adult Male Subjects in China

Pharmacokinetics

China
Xizang Haisco Pharmaceutical Co., Ltd

Active, not recruiting

Pharmacokinetics, Mass Balance, and Metabolism of [14C]HSK31679 in Healthy Adult Male Volunteers.

Healthy

China
Shanghai Henlius Biotech

Completed

Mass Balance Study of [14C]HLX208 in China Healthy Subjects

Mass Balance Study in Healthy Subjects

China
Eli Lilly and Company

Completed

A Study of Carbon-14-Labelled [14C] LY3871801 in Healthy Male Participants

Healthy

United States
Eli Lilly and Company

Completed

A Study of Carbon-14-Labelled [14C] LY3556050 in Healthy Male Participants

Healthy

United States
Sunshine Lake Pharma Co., Ltd.

Completed

ADME Study of [14C]- Rongliflozin in Healthy Male Subjects

Healthy Adult Male Volunteers

China
Sunshine Lake Pharma Co., Ltd.

Completed

ADME Study of [14C]- Larotinib in Healthy Male Subjects

Healthy Adult Male Volunteers

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Mass Balance and Biotransformation Study of [14C]SKLB1028 in Chinese Healthy Male Subjects

Healthy Male Subjects

China
Corcept Therapeutics

Completed

Single Dose Absorption, Distribution, Metabolism, and Excretion Study of [14C]-CORT113176 in Healthy Male Participants

Healthy

United Kingdom
BeiGene

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-Pamiparib in Participants With Advanced Cancer

Advanced Solid Tumors

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study to Evaluate the Mass Babance and Biotransformation of [14C]SHR6390 in Healthy Adult Male Volunteers

Healthy Adult Male Volunteers

China
Arthrosi Therapeutics
Celerion

Completed

Single-dose AME Study With [14C]AR882 in Healthy Male Subjects

Healthy Volunteers

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study to Evaluate the Mass Balance and Biotransformation of [14C]-Fluzoparib in Chinese Patients With Solid Tumor

Solid Tumor

China
Jiangsu vcare pharmaceutical technology co., LTD

Completed

The Mass Balance and Biotransformation of [14C] Vicagrel in Healthy Man

Healthy Male Adult

China
Enyo Pharma

Completed

Mass Balance Study to Investigate the Absorption, Metabolism and Excretion of [14C]-EYP001a After a Single Oral Dose

Healthy

Netherlands
Corcept Therapeutics

Completed

A Study Designed to See How [14C]-CORT125134 is Taken up, Broken Down and Removed From the Body

Healthy

United Kingdom

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