Search clinical trials for: β-blockers

Total 8949 results

UCB Pharma

Completed

Assess Safety and Efficacy of Lacosamide in Patients With Partial Seizures

Epilepsy

France, Poland, United Kingdom, Germany, Spain, Finland, Australia, Russian Federation, Hungary, Lithuania, Sweden, Czechia, Croatia
Bial - Portela C S.A.

Completed

Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly Patients

Epilepsy

Spain, Bulgaria, Austria, Croatia, Czechia, France, Germany, Poland, Portugal, Romania
The Cleveland Clinic
UCB Pharma

Completed

Randomized Controlled Trial to Assess Effects of Lacosamide on Sleep and Wake in Adults With Focal Epilepsy

Partial Epilepsy

United States
Bial - Portela C S.A.

Completed

An Open-label, Single-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Epilepsy

South Africa
UCB Pharma

Completed

Belgian Drug-utilization Study to Evaluate the Use of VIMPAT® as Adjunctive Treatment of Partial Onset Seizures in Subjects Aged 16 and Older

Seizures

Belgium
Georgetown University

Unknown

A Crossover Pilot Study of the Effect of Amiloride on Proteinuria

Proteinuria

United States
University of North Carolina
Cystic Fibrosis Foundation

Completed

Efficacy of Amiloride and Hypertonic Saline in Cystic Fibrosis

Cystic Fibrosis

United States
MEDA Pharma GmbH & Co. KG

Completed

To Evaluate the Impact of Oral Flecainide on Quality of Life in Patients With Paroxysmal Atrial Fibrillation

Atrial Fibrillation

France
Academisch Ziekenhuis Maastricht

Completed

Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber Neuropathy

Small Fiber Neuropathy

Netherlands
Sun Yat-sen University
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Characteristic Study on Chinese Patients With Multiple Sclerosis

Multiple Sclerosis

China
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Active, not recruiting

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene

Hypertension

United States
UCB Pharma

Completed

An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic Neuropathy

Painful Diabetic Neuropathy
UCB Pharma

Completed

Study to Investigate Lacosamide as Add-on Therapy in Subjects ≥4 Years to <17 Years of Age With Partial Onset Seizures

Epilepsy

United States, Argentina, Australia, Belgium, Bulgaria, Colombia, Croatia, Czechia, Estonia, Georgia, Hungary, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Mexico, Montenegro, Poland, Romania, Russian Federation, Serbia, Sl... and more
Eisai Inc.

Completed

A Post-marketing Study Evaluating Eslicarbazepine Acetate (ESL) as Adjunctive Treatment in Partial-Onset Seizures (Study E2093-E044-404) (EPOS)

Partial Onset Seizures

France, United Kingdom, Germany, Denmark, Czech Republic, Norway, Sweden, Ireland
UCB Pharma

Completed

Effect of Lacosamide 200 mg Twice a Day (Bid) on Single Dose Warfarin 25 mg in Healthy Males

Healthy Volunteers

Netherlands
Korea University Guro Hospital

Enrolling by invitation

Perfusion Index for Predicting Brachial Plexus Block Success Under General Anesthesia

Disorder of Shoulder

Korea, Republic of
Maastricht University Medical Center

Completed

Early Vascular Adjustments to Prevent Preeclampsia

Preeclampsia | HELLP Syndrome | Small for Gestational Age at Delivery

Netherlands
Nanjing Medical University

Unknown

Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery

Coronary Artery Disease | Acute Coronary Syndrome

China
Lupin Ltd.

Recruiting

Open Label Study in Adolescents and Children With Myotonic Disorders

Myotonic Dystrophy

France
Lupin Ltd.

Recruiting

Open-label Extension Study in Paediatric Patients Who Have Completed the MEX-NM-301 Study.

Myotonic Disorders

France
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Flecainide in Treating Patients With Chronic Neuropathic Pain

Pain

United States
Lupin Ltd.

Active, not recruiting

An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders

Myotonic Dystrophy

France, Germany, United Kingdom
Centre Hospitalier Saint Joseph Saint Luc de Lyon

Unknown

ZEBinix® Retention Rate in Epilepsy in Elderly Patients (ZEBRE)

Epilepsy | Aging | Epilepsy; Seizure | Aging Disorder

France
Bial - Portela C S.A.

Completed

Efficacy and Safety of Eslicarbazepine Acetate as Adjunctive Therapy for Refractory Partial Seizures

Refractory Partial Epilepsy

Portugal
Samsung Medical Center

Completed

Efficacy of Propafenone Versus Dronedarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation

Atrial Fibrillation

Korea, Republic of
Tharick Pascoal
National Institute on Aging (NIA)

Recruiting

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease (HEAD)

Alzheimer Disease

United States, Canada, Spain
University of Cambridge
King's College London; Imperial College London; Barts & The London NHS Trust; University... and other collaborators

Unknown

Comparison of Single and Combination Diuretics in Low-Renin Hypertension (PATHWAY3)

Hypertension

United Kingdom
UCB Pharma

Completed

A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).

Postherpetic Neuralgia
University of Washington
Massachusetts General Hospital

Completed

Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (Mexiletine-2)

Sporadic Amyotrophic Lateral Sclerosis

United States
UCB Pharma

Completed

eValuation of the Efficacy and toleRability of Vimpat When Added to lEvetiracetam (VERVE)

Epilepsy

United States, Australia, Bulgaria, Denmark, France, Germany, Romania, Spain, Sweden
Bial - Portela C S.A.

Completed

A Placebo-controlled Study to Investigate Safety and Efficacy of BIA 2-093

Epilepsy

Portugal
University of Southern Denmark
Region of Southern Denmark

Completed

Central and Peripheral Nervous System Changes as Markers of Disease Progression in Multiple Sclerosis

Multiple Sclerosis | Drug Effect | Genetic Disease | Central Nervous System Lesion | Neurophysiologic Abnormality | Neurodegeneration | Neurologic Deficits | Peripheral Nervous System Problem

Denmark
Lawrence Fong
CellSight Technologies, Inc.

Terminated

Functional Imaging of T-Cell Activation With [18F]F-AraG in Urothelial Carcinoma Patients Receiving Neoadjuvant Therapy or Patients With Cancer Receiving Standard of Care Anti-PD-1/L1

Bladder Cancer

United States
University Hospital Tuebingen

Terminated

Amiloride in Nephrotic Syndrome (AMILOR)

Edema | Nephrotic Syndrome | Sodium Retention

Germany
University of Southern Denmark
Odense University Hospital; Region of Southern Denmark

Completed

Increased Activity of ENaC in Proteinuric Kidney Transplant Recipients

Kidney Transplant; Complications

Denmark
University of Southern Denmark
Odense University Hospital; The Ministry of Science, Technology and Innovation... and other collaborators

Unknown

Increased Activity of a Renal Salt Transporter (ENaC) in Diabetic Kidney Disease

Hypertension | Diabetic Nephropathies

Denmark
Assistance Publique - Hôpitaux de Paris

Completed

Descriptive and Retrospective Analysis of Acute Myocarditis Associated With Pandemic COVID-19 in Children (HEART-COVID)

COVID-19

France
A.Menarini Asia-Pacific Holdings Pte Ltd

Unknown

A Study of Pharmacokinetics and Safety of Ranolazine PR in Healthy Korean and Caucasian Male Subjects

Healthy Male Individuals

Korea, Republic of
Lawson Health Research Institute

Completed

Removal of Beta Blocker Drugs by Hemodialysis

Chronic Kidney Diseases
University of Rochester

Completed

Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease

Charcot Marie Tooth Disease

United States
UCB Pharma SA

Completed

Bioavailability/Bioequivalence Study Between Lacosamide Tablet and Solution for Infusion in Healthy Japanese Subjects

Healthy Volunteers

United Kingdom
Mayo Clinic

Completed

Effects of Mexiletine on Colonic Transit in a Patient With Irritable Bowel Syndrome - Constipation (IBS-C)

IBS
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
Ottawa Hospital Research Institute

Recruiting

RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency Department

Atrial Fibrillation

Canada
Assistance Publique - Hôpitaux de Paris
Fonds de Dotation ACTION

Active, not recruiting

Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Arrhythmia or Tachycardia (AFLOAT)

Patent Foramen Ovale | Cryptogenic Stroke | Atrial Arrhythmia

France
David Filgueiras-Rama
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

Completed

Predictive Factors to Effectively Terminate Paroxysmal Atrial Fibrillation by Blocking Atrial Selective Ionic Currents (SELECTCARFAP)

Paroxysmal Atrial Fibrillation

Spain
Daiichi Sankyo, Inc.

Completed

Relative Bioavailability DS-1971a Suspension and Tablets and Food Effect on DS-1971a Tablets

Healthy

United Kingdom
Sunovion

Completed

Eslicarbazepine Acetate Monotherapy Long Term Study

Epilepsy

United States, Canada, Bulgaria, Ukraine, Czechia, Serbia
Bial - Portela C S.A.

Completed

Pharmacokinetics, Efficacy and Tolerability of BIA 2-093

Epilepsy

Romania
Bjorn Oskarsson, MD
University of California, Davis; ALS Association

Completed

Mexiletine for the Treatment of Muscle Cramps in ALS

Muscle Cramps in Amyotrophic Lateral Sclerosis

United States

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