Search clinical trials for: 0.9% Normal saline

Total 24195 results

Chimerix

Terminated

Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Acute Lung Injury | Coronavirus Disease 2019 (COVID-19)

United States
Seoul National University Bundang Hospital

Completed

Intracoronary Darbepoetin-alpha to Reduce The Infarct Size and Post-Infarct Remodeling

Myocardial Infarction

Korea, Republic of
First Affiliated Hospital Xi'an Jiaotong University
Xijing Hospital; Shaanxi Provincial People's Hospital; Second Affiliated Hospital... and other collaborators

Unknown

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Cerebral Palsy | Intracranial Hemorrhages | Premature Infants | Periventricular Leukomalacia

China
Vac4All
University of Bamako

Completed

Proof-of-Concept Study of MSP3-LSP Vaccine to Protect Against Malaria in Africa (MSP3-POC)

Malaria

Mali
University of California, San Francisco

Completed

Regional Anesthesia (Supra-Orbital and Infra-Orbital Nerve Block) (SION) for Pain Management in Trans-sphenoidal Hypophysectomy (SION)

Post-operative Surgical Pain

United States
University of Arkansas

Recruiting

Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence

Squamous Cell Carcinoma of Head and Neck

United States
Green Valley Group of China

Unknown

Effects of Salvianolate Injection on Myocardial Microcirculation in Patients With Acute STEMI After Primary PCI (SISTEMI)

STEMI - ST Elevation Myocardial Infarction

China
University Hospital Rijeka
University of Rijeka

Unknown

Balanced Crystalloid Solutions for Acute Pancreatitis

Acute Pancreatitis

Croatia
McMaster University
National Health and Medical Research Council, Australia; Canadian Institutes... and other collaborators

Completed

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (REVISE)

Gastrointestinal Hemorrhage (Clinically Important, Upper)

Canada, Australia, United States, Brazil, Kuwait, Pakistan, Saudi Arabia, United Kingdom
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health...

Completed

Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma (HypoResus)

Hemorrhagic Shock | Blunt Trauma | Penetrating Wound

United States, Canada
University of Malaya

Unknown

Comparison of an Isotonic Balanced Fluid, Sterofundin® , With 0.9% Saline in Traumatic Brain Injury(TBI) (FLUID)

Brain Injuries

Malaysia
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery (POINT)

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Neurologic Manifestations

United States
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of SPC4955 in Healthy Subjects

Hypercholesterolemia

Germany
Yonsei University

Completed

The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries.

Spinal Surgery

Korea, Republic of
Vanderbilt University

Completed

Isotonic Solutions and Major Adverse Renal Events Trial in the Medical Intensive Care Unit (SMART-MED)

Critical Illness | Acute Kidney Injury

United States
Vanderbilt University

Completed

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG) (SMART-SURG)

Critical Illness | Acute Kidney Injury

United States
Rigshospitalet, Denmark

Completed

IL-6 Regulation of Substrate Metabolism and Influence of Obesity

Healthy | Obesity

Denmark
rEVO Biologics

Completed

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (PRESERVE-1)

Preeclampsia

United States
CSL Behring

Terminated

Safety and Efficacy of ALD518 for Reducing Oral Mucositis in Head and Neck Cancer Subjects

Oral Mucositis

United States, Canada, Australia, Germany, Italy, Austria
Imperial College London
Medical Research Council

Completed

Safety and Pharmacokinetic Study of Y242 in Adult Subjects (Y242-01)

Obesity

United Kingdom
Santaris Pharma A/S

Terminated

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

Hypercholesterolemia

Netherlands
Seoul National University Hospital
Green Cross Corporation; LSK Global Pharma Services Co. Ltd.

Completed

Efficacy and Safety of Anthrax Vaccine, GC1109

Anthrax

Korea, Republic of
Seoul National University Hospital
Seoul St. Mary's Hospital; Seoul National University Bundang Hospital; Gachon... and other collaborators

Completed

Balanced Salt Solution Versus 0.9% Saline Infusion for Prevention of Contrast-induced Acute Kidney Injury (BASIC Trial)

Renal Insufficiency, Chronic | Acute Kidney Injury | Contrast Media Reaction

Korea, Republic of
Nicholas M Mohr

Completed

Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation

Emergencies | Fluid Loss | Symptom Complex, Triple

United States
Mukoviszidose Institut gGmbH
Cystic Fibrosis Foundation

Completed

Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients

Cystic Fibrosis

Germany
Chimerix

Terminated

Dociparstat in Combination With Standard Chemotherapy for the Treatment of Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Neurological... and other collaborators

Terminated

Hypertonic Resuscitation Following Traumatic Injury

Shock, Traumatic

United States, Canada
Vanderbilt University

Completed

Saline Against Lactated Ringers or Plasmalyte in the Emergency Department (SaLt-ED)

Critical Illness | Acute Kidney Injury

United States
ImmuneMed, Inc.

Completed

Safety, Tolerability, Pharmacokinetic Characteristics of hzVSF-v13 in Healthy Male Volunteers

Healthy

Korea, Republic of
University of Edinburgh
NHS Lothian

Completed

Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation (HOT)

Ischemia-reperfusion Injury | Graft Failure

United Kingdom
The Hospital for Sick Children
Canadian Cystic Fibrosis Foundation

Completed

The Effect of Hypertonic Saline on the Lung Clearance Index in Patients With Cystic Fibrosis

Cystic Fibrosis

Canada
University of Alberta

Withdrawn

A Study to Systematically Assess the Efficacy and Safety of Intravenous Albumin Infusions in Severe POTS

Postural Orthostatic Tachycardia Syndrome
University of Texas Southwestern Medical Center

Completed

Heparin Versus Normal Saline in Peripherally Inserted Central Catheter Lines

Cancer

United States
University of Southern California

Completed

Oral Hydration for Mild to Moderate Hyperglycemia in the Emergency Department

Hyperglycemia

United States
Noveome Biotherapeutics, formerly Stemnion

Completed

Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis

Periodontal Disease

United States
Hamad Medical Corporation

Completed

"Palivizumab Therapy for RSV-bronchiolitis"

Respiratory Syncytial Virus-bronchiolitis

Qatar
Ottawa Hospital Research Institute

Completed

Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients (FLUID)

Fluid Therapy

Canada
Arch Biopartners Inc.

Completed

A Phase I Study to Evaluate LSALT Peptide

None - Study is to Determine Safety in Healthy Participants

Australia
University Hospital, Basel, Switzerland

Completed

Perianal Nerval Block in Proctological Interventions

Hemorrhoids | Perianal Fistula | Fissure in Ano

Switzerland
Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd

Completed

the Safety and Efficacy of Meplazumab in Patients With COVID-19

Covid19

China
Assiut University

Completed

Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs

Blood Loss | Terlipressin
Ho Cheol Shin, M.D., Ph.D.
Green Cross Corporation; Ajou University School of Medicine; Symyoo

Completed

Investigator Initiated Clinical Study to Explore the Efficacy and Safety of Human Placenta Hydrolysate in the Chronic Fatigue Patients

Chronic Fatigue Syndrome | Idiopathic Chronic Fatigue

Korea, Republic of
Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd

Completed

Study to Assess the Effect of Meplazumab on COVID-19

COVID-19

Brazil
University of North Carolina, Chapel Hill
United States Department of Defense; RTI International; Environmental Protection...

Completed

Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART) (Endoheart)

Healthy

United States
Hamilton Health Sciences Corporation

Completed

Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial

Hyponatremia | Hypernatremia

Canada
St Joseph University, Beirut, Lebanon

Completed

Ultrasound Guided Quadratus Lumborum Block for Postoperative Pain in Abdominoplasty

Pain

Lebanon
The Catholic University of Korea

Completed

Effects of Joint Effusion on Quadriceps Muscle

Knee Osteoarthritis

Korea, Republic of
Texas Cardiac Arrhythmia Research Foundation

Suspended

Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation

Ventricular Arrythmia

United States
MassBiologics

Terminated

Study in Hepatitis C Virus (HCV) Infected Patients Undergoing Liver Transplantation to Evaluate a Human Monoclonal Antibody Against Hepatitis C (MBL-HCV1)

Liver Transplantation | HCV Infection

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Terminated

Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI)

Brain Injuries, Traumatic

United States, Canada

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