Search clinical trials for: 13-cis-retinoic acid

Total 675 results

Kafrelsheikh University
1-Foshan University Laboratory of Emerging Infectious Disease Institute of... and other collaborators

Not yet recruiting

Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized) (Isotretinoin)

COVID19

Egypt
University of Iowa
Molecular Insight Pharmaceuticals, Inc.

Withdrawn

90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)

Neuroendocrine Tumor | Neuroblastoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)

Lung Diseases | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease | Emphysema
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Completed

Chemoprevention Study of Oral Cavity Squamous Cell Carcinoma

Squamous Cell Carcinoma | Oral Cavity

Taiwan
Kafrelsheikh University

Not yet recruiting

Investigating the Role of 13cis Retinoic Acid in the Treatment of COVID-19 and Enhancement of Its Spike Protein Based Vaccine Efficacy and Safety. (Isotretinoin)

Covid19 Vaccine
M.D. Anderson Cancer Center
AstraZeneca

Terminated

ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma

Neuroblastoma

United States
Eastern Cooperative Oncology Group

Completed

Double Blind Phase III Trial of Effects of Low Dose 13-Cisretinoic Acid on Prevention of Second Primaries in Stages I-II Head and Neck Cancer

Stage I-II Head and Neck Cancer
Kafrelsheikh University
Damietta University

Unknown

Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment (Antibodies)

COVID-19
Nova Laboratories Limited

Completed

Oral Liquid 13-cis-retinoic Acid (13-CRA) (My-CRA)

Neuroblastoma

United Kingdom
National Cancer Institute (NCI)

Completed

Belinostat and Isotretinoin in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Adult Solid Neoplasm

United States
Peter Zage
Exelixis

Recruiting

Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors

Solid Tumor

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma

Recurrent Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

RA-4: 13-cis Retinoic Acid for Treatment of Men With Azoospermia

Male Infertility, Azoospermia

United States
Memorial Sloan Kettering Cancer Center

Completed

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Non-Myeloablative Therapy in Patients With High-Risk Neuroblastoma

Neuroblastoma

United States
Memorial Sloan Kettering Cancer Center

Terminated

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of Second or Greater Remission of High-Risk Neuroblastoma

Neuroblastoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma

Recurrent Neuroblastoma | Refractory Neuroblastoma

United States, Canada
BeiGene

Completed

Evaluation of the Safety and Pharmacokinetics of Dinutuximab Beta as Maintenance Therapy in Chinese Patients With High-risk Neuroblastoma

High-risk Neuroblastoma

China
University of Aberdeen

Completed

A Pilot Study of the Effects of Isotretinoin on Cognition, Learning and Memory

Acne Vulgaris

United Kingdom
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery

HIV-1 Infection

United States, Puerto Rico
Kafrelsheikh University

Not yet recruiting

Combination of Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP and Isotretinoin Could be Promising Treatment for COVID-19 Infection- and Its Inflammatory Complications

COVID
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Ch14.18, Sargramostim, Aldesleukin, and Isotretinoin After Autologous Stem Cell Transplant in Treating Patients With Neuroblastoma

High Risk Neuroblastoma

United States
Federal University of São Paulo

Unknown

Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage

Photoaging | Photodamage

Brazil
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas

Brain and Central Nervous System Tumors
Memorial Sloan Kettering Cancer Center

Completed

High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation

Neuroblastoma

United States
Kafrelsheikh University
Ministry of Health, Saudi Arabia

Not yet recruiting

Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19

Tuberculosis

Egypt, Saudi Arabia
National Cancer Institute (NCI)

Active, not recruiting

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
University Hospital, Gentofte, Copenhagen

Completed

Single Dose of 9-cis-retinoic Acid in Hepatic Patients

Hepatic Insufficiency

Denmark
Kafrelsheikh University

Unknown

Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 (Isotretinoin)

Covid19

Egypt
Shandong University

Withdrawn

All-Trans Retinoic Acid (ATRA) Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)

Purpura | Idiopathic Thrombocytopenic Purpura

China
United Therapeutics

Terminated

A Study of MAb-3F8 Plus Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus 13-cis-Retinoic Acid (RA) Plus GM-CSF in Primary Refractory Neuroblastoma Patients

Primary Refractory Neuroblastoma

United States
Memorial Sloan Kettering Cancer Center

Completed

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Primary Refractory Neuroblastoma in Bone Marrow

Neuroblastoma

United States
Kafrelsheikh University
Ministry of Health, Saudi Arabia; Foshan University Laboratory of Emerging... and other collaborators

Not yet recruiting

Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.

Post COVID-19 Anosmia (Loss of Smell)

China, Egypt, Saudi Arabia
National Cancer Institute (NCI)

Completed

A Phase I Trial of Tamoxifen and 9-Cis-Retinoic Acid in Breast Cancer Patients

Breast Cancer | Breast Neoplasm

United States
Kafrelsheikh University

Unknown

Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword?

Covid19
Peking University People's Hospital
Beijing Friendship Hospital; Beijing Tongren Hospital; Beijing Hospital; Navy General...

Not yet recruiting

The Combination of ATRA and Eltrombopag as the Treatment of Steroid-resistant/Relapse ITP Based on MSC-C5b-9

Purpura, Thrombocytopenic, Idiopathic

China
NYU Langone Health
Children's Hospitals and Clinics of Minnesota; Schneider Children's Hospital

Completed

Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors

Brain Tumors

United States, Canada
University of Colorado, Denver

Completed

13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer (13-Cis)

Lung Cancer | Drug Toxicity

United States
Kafrelsheikh University

Unknown

Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 (TMPRSS2)

Covid19
University Hospital, Gentofte, Copenhagen

Completed

Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease

Hepatic Insufficiency

Denmark
Universidad Autonoma de San Luis Potosí
Hospital Central "Dr. Ignacio Morones Prieto"

Completed

Opsin Receptors in Melasma

Melasma

Mexico
Sun Yat-sen University

Completed

Retinoic Acid Supplementation and Subjects With Hypercholesterolemia

Hypercholesterolemia

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Clinical Study Evaluating the Efficacy and Safety of Retinoic Acid in Patients With 15q11-q13 Duplication Syndrome

Treatment Adherence | Autism | Dup15Q Syndrome | Retinoic Acid

China
Peking University People's Hospital
Qilu Hospital of Shandong University; Beijing Tongren Hospital; Beijing Municipal... and other collaborators

Completed

The Combination of ATRA and Danazol as Second-line Treatment in Adult Immune Thrombocytopenia

Autoimmune Thrombocytopenia

China
Yale University
Mayo Clinic

Completed

Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis

Cholangitis, Sclerosing

United States
Yale University

Terminated

An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis

Cholangitis, Sclerosing

United States
Peking University People's Hospital
Ministry of Science and Technology of the People´s Republic of China

Not yet recruiting

Randomized,International Multi-center Clinical Trial of RIF Plus RA for Non-high-risk APL (RIF)

Acute Promyelocytic Leukaemia
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

AIDA 2000 Guidelines

Acute Promyelocytic Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

"AIDA" Protocol (LAP 0493)

Leukemia

Italy, Belgium, Germany, Netherlands, Turkey
Amsterdam UMC, location VUmc
UMC Utrecht; Erasmus Medical Center; University of Turin, Italy; Vejle Hospital

Completed

Daratumumab in Combination With ATRA (DARA/ATRA)

Multiple Myeloma

Netherlands
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Active, not recruiting

Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme | Anaplastic Glioma

United States

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