Search clinical trials for: 23.4% Hypertonic saline

Total 11959 results

Bayer
Orion Corporation, Orion Pharma

Completed

Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers

Prostatic Neoplasms

Germany
Grifols Therapeutics LLC

Terminated

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Institute of Tropical Medicine, Belgium
Liverpool School of Tropical Medicine; Kamuzu University of Health Sciences; Kwame... and other collaborators

Completed

Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria (PREGACT)

Malaria in Pregnancy

Burkina Faso, Ghana, Malawi, Zambia
University Medicine Greifswald

Completed

Effects of Propranolol (vs. Placebo) on Information Processing During Presentation of Emotionally Arousing Pictures (BBEmoMem_G)

Emotions

Germany
Boehringer Ingelheim

Completed

Relative Bioavailability of Single Doses of Dabigatran Etexilate When Administered Alone or in Combination With a Single Dose of Ketoconazole or in Combination With q.d. Ketoconazole at Steady State in Healthy Male and Female Volunteers

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BIBR 1048 MS Single Doses With or Without Pantoprazole in Healthy Subjects

Healthy
Abbott

Completed

A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy

HIV Infections

United States, Canada, Puerto Rico, Switzerland, France, Germany, United Kingdom, Australia, Brazil, Austria, Denmark, Poland, South Africa, Spain
Kecioren Education and Training Hospital

Completed

Ibuprofen in Migraine Patients

Migraine Without Aura

Turkey
Institut fuer anwendungsorientierte Forschung und...
University Medical Center Goettingen

Completed

Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - ICUTI

Urinary Tract Infection

Germany
Planned Parenthood League of Massachusetts
Society of Family Planning

Completed

Intramuscular Ketorolac Versus Oral Ibuprofen for Pain Relief in First Trimester Suction Curettage

Pain

United States
Henry Ford Health System

Unknown

NdYag Laser for Acne Keloidalis Nuchae

Acne Keloidalis Nuchae | NdYag Laser | AKN | Acne Keloidalis | AK | Dermatitis Papillaris Capillitii | Folliculitis Keloidalis Nuchae | Sycosis Nuchae | Acne Keloid | Keloidal Folliculitis | Lichen Keloidalis Nuchae | Folliculitis Nuchae Scleroticans | Sycosis Framboesiformis

United States
Shandong Cancer Hospital and Institute

Unknown

Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma

Liver Diseases | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Carcinoma, Hepatocellular | Liver Neoplasms | HBV | PHENYTOIN/SORAFENIB [VA Drug Interaction] | DOXORUBICIN/TRASTUZUMAB [VA Drug Interaction]

China
MediGene

Completed

EndoTAG-1 / Gemcitabine Combination Therapy to Treat Locally Advanced and/or Metastatic Adenocarcinoma of the Pancreas

Adenocarcinoma | Metastasis | Pancreas Neoplasms

Ukraine, Czech Republic, Hungary
Heron Therapeutics

Completed

HTX-011 Administration Study in Planned Caesarean Section Procedure

Analgesia

United States
Cairo University

Unknown

Human Chorionic Gonadotrophin & Trigger

Ovulation Disorder

Egypt
Aziende Chimiche Riunite Angelini Francesco S.p.A
Cross Research S.A.

Completed

Bioequivalence Study of Ibuprofen 400 mg/10 mL Oral Suspension vs. MOMENTACT 400 mg Film-coated Tablet

Healthy

Switzerland
Aziende Chimiche Riunite Angelini Francesco S.p.A
Cross Research S.A.

Completed

Bioequivalence Study of Ibuprofen 200 mg/5 mL Oral Suspension vs. MOMENT 200 mg Coated Tablet

Healthy

Switzerland
Oregon Health and Science University
Genentech, Inc.

Completed

Combination Ranibizumab and Bromfenac for Neovascular Age-related Macular Degeneration

Age-Related Macular Degeneration

United States
Cairo University

Not yet recruiting

Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation

Alveolar Bone Loss

Egypt
Intensity Therapeutics, Inc.
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 (IT-01)

Sarcoma | Lymphoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Bile Duct Cancer | Colon Cancer | Liver Cancer | Squamous Cell Carcinoma | Chordoma of Sacrum

United States, Canada
University of California, San Francisco

Active, not recruiting

Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder

Rotator Cuff Tear Arthropathy

United States
University Hospital, Basel, Switzerland

Completed

Potential Benefit of the Combination of Metamizole and Ibuprofen After Third Lower Molar Extraction (NovIbu)

Pain, Postoperative

Switzerland
University of Florida
Gateway for Cancer Research; Cellworks Group Inc.

Withdrawn

iCare 2: Personalized Genomic Mutation Informed Treatment of Patients With Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
Medherant Ltd
Cooperative Clinical Drug Research and Development AG (CCDRD AG)

Completed

pK of a Novel 200 mg Ibuprofen Medicated Plaster

Healthy

Bulgaria
University of California, San Francisco
National Institute of General Medical Sciences (NIGMS)

Completed

Drug-Drug Interaction Study With Pravastatin and Cyclosporine

Healthy

United States
Biogen

Completed

Dose-Finding Safety Study of BIIB014 in Early-Stage Parkinson's Disease (MOBILE)

Parkinson's Disease

Poland, Israel, Serbia
Loyola University

Recruiting

Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

Pain, Postoperative

United States
University of Oxford
London School of Hygiene and Tropical Medicine; Medical Research Council; Wellcome... and other collaborators

Completed

A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia (SEARCH)

Pneumonia

Kenya
Sint Maartenskliniek

Completed

Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block

Arthroplasty, Replacement, Knee

Netherlands
Tanta University

Completed

Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children

Emergence Delirium | Postoperative Nausea and Vomiting | Post Operative Pain

Saudi Arabia
Barts & The London NHS Trust

Completed

A Study Investigating the Efficacy of GON Blocks.

Migraine | Chronic Migraine, Headache

United Kingdom
Lumbini Medical College

Completed

Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy

Throat Disorder

Nepal
St George Hospital, Australia
St George & Sutherland Medical Research Foundation

Unknown

A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain (SCIATICA)

Acute Sciatica

Australia
Beijing Friendship Hospital
Changhai Hospital; Peking Union Medical College Hospital; Peking University Cancer...

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus

Invasive Aspergillosis | Invasive Candidiasis

China
RenJi Hospital
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University and other collaborators

Recruiting

Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant (EARLYmyo-LVT)

ST Segment Elevation Myocardial Infarction | Left Ventricular Thrombus

China
Institut Pasteur de Dakar
Ministry of Health, Senegal; Fann Hospital, Senegal; Diamniadio Children Hospital... and other collaborators

Terminated

Efficacy and Safety Evaluation of Treatment Regimens in Adult COVID-19 Patients in Senegal (SEN-CoV-Fadj)

COVID-19

Senegal
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute

Completed

Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer (CANVAS)

Cancer | Venous Thromboembolism | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE) | Blood Clot

United States
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Active, not recruiting

Caveolin-1 and Vascular Dysfunction

Hypertension | Insulin Resistance

United States
Ensysce Biosciences
National Institute on Drug Abuse (NIDA)

Completed

Oral Nafamostat in Healthy Volunteers

Pharmacokinetics

United States
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Terminated

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

Chronic Obstructive Pulmonary Disease | Alpha1-antitrypsin Deficiency

United States, Canada, Australia
Chong Kun Dang Pharmaceutical

Completed

A Study Evaluating the Efficacy and Safety of CKD-314 (Nafabelltan) in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia

COVID-19

Russian Federation
Sanofi

Terminated

Evaluation of Weekly Idrabiotaparinux Sodium Versus Oral Adjusted-dose Warfarin to Prevent Stroke and Systemic Thromboembolic Events in Patients With Atrial Fibrillation (BOREALIS-AF)

Atrial Fibrillation

South Africa, Thailand, Chile, Guatemala, Ukraine, United States, Argentina, Australia, Austria, Belarus, Brazil, Bulgaria, Canada, Colombia, Costa Rica, Croatia, Czech Republic, Denmark, Egypt, Estonia, Finland, France, Greece, India, ... and more
Bayer

Completed

Microgynon Riociguat Drug Interaction Study in Healthy Postmenopausal Women

Drug Interactions

Germany
Boehringer Ingelheim

Completed

Bioavailability of BIBR 953 ZW After Oral Administration of BIBR 1048 MS in Healthy Subjects

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BIBR 963 ZW After 50 mg of BIBR 1048 MS With and Without of Pantoprazole in Healthy Subjects

Healthy
Sanofi

Completed

Evaluating the Use of SR34006 Compared to Warfarin or Acenocoumarol in Patients With Atrial Fibrillation (AMADEUS)

Atrial Fibrillation

Canada, Netherlands, United States, United Kingdom, Italy, Australia, Denmark, France, New Zealand, Poland
Istituto Clinico Sant'Ambrogio
Istituto Clinico Humanitas; Azienda Ospedaliera Niguarda Cà Granda; Centro Cardiologico...

Unknown

Bivalirudin/Prasugrel Versus Abciximab/Clopidogrel in Patients Presenting With STEMI

ST-Elevation Myocardial Infarction | Primary Percutaneous Coronary Intervention

Italy
Asan Medical Center
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Overcome Biochemical Aspirin Resistance Through Cilostazol Combination (ARCC)

Cerebral Infarction

Korea, Republic of

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