Search clinical trials for: 5-fluorouracil/leucovorin

Total 8691 results

PharmaEngine

Terminated

A Study of PEP503(Radio-enhancer) With Radiotherapy and Chemotherapy for Patients With Rectal Cancer

Rectal Cancer

Taiwan
US Oncology Research
Bristol-Myers Squibb; Eli Lilly and Company

Completed

Pre-op Rectal ChemoRad +/- Cetuximab

Rectal Cancer

United States
GERCOR - Multidisciplinary Oncology Cooperative...
Merrimack Pharmaceuticals

Completed

A Dose Escalation Study of MM-398 Plus Irinotecan in Patients With Unresectable Advanced Cancer (DOUBLIRI)

Unresectable Advanced Cancer

France
Yuhong Li

Completed

mFOLFIRINOX as First-Line Chemotherapy in Treating Chinese Patients With Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

China
Jessa Hospital

Unknown

Implementation of Pre-emptive Geno- and Phenotyping in 5-Fluorouracil- or Capecitabine-treated Patients

Esophageal Cancer | Colon Cancer | Pancreas Cancer | Stomach Tumor | Anal Tumor
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States, Puerto Rico
Hoffmann-La Roche

Terminated

Sequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal Cancer (STEAM)

Colorectal Neoplasms

United States
Seattle Cancer Treatment and Wellness Center

Unknown

Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer

Stage III Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Adenocarincoma of Pancreas

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

Gastric Adenocarcinoma | Oligometastasis | Stage IV Esophageal Cancer AJCC v7 | Stage IV Gastric Cancer AJCC v7 | Stage IV Esophageal Adenocarcinoma AJCC v7

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Infusional Fluorouracil and Weekly Docetaxel for Gastric Cancer With Bone Marrow Involvement and DIC

Gastric Cancer | Disseminated Intravascular Coagulation | Bone Marrow Metastasis

China
National Eye Institute (NEI)

Completed

Fluorouracil Filtering Surgery Study (FFSS)

Glaucoma
University of Washington

Recruiting

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study (CTS)

Chalazion

United States
John Hays
Sanofi

Unknown

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Cancer and Leukemia... and other collaborators

Terminated

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Actavis Inc.

Completed

Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis

Actinic Keratosis

United States
NCIC Clinical Trials Group
North Central Cancer Treatment Group

Completed

Immediate Compared With Delayed Chemotherapy in Advanced Colorectal Cancer Without Signs or Symptoms of Disease

Colorectal Cancer

United States
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; The First Affiliated Hospital... and other collaborators

Completed

Sorafenib Alone Versus Sorafenib Combined With HAIC for Advanced HCC

Hepatocellular Carcinoma

China
Sun Yat-sen University
Guangzhou No.12 People's Hospital; Kaiping Central Hospital

Unknown

Phase 2 Study of Sorafenib Plus HAIC of FOLFOX vs. Sorafenib Plus HAIC of OXA for Advanced HCC

Hepatocellular Carcinoma

China
Sun Yat-sen University
Guangzhou No.12 People's Hospital; Kaiping Central Hospital

Terminated

The Efficacy and Safety of Retreatment With TAI for Patients Who Showed TACE-resistant: a Randomized Controlled Trial

Hepatocellular Carcinoma

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer

Colorectal Cancer

United States, Puerto Rico, Canada
California Cancer Consortium
National Cancer Institute (NCI)

Terminated

Bortezomib, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Stomach Cancer

Gastric Cancer

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer

Colorectal Cancer

United States
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital... and other collaborators

Unknown

HAIC of FOLFOX vs. HAIC of OXA for Advanced HCC

Hepatocellular Carcinoma

China
Johann Wolfgang Goethe University Hospital

Unknown

Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

Germany
VA Office of Research and Development

Completed

CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial (VAKCCT)

Skin Diseases | Carcinoma | Carcinoma, Squamous Cell | Carcinoma, Basal Cell | Neoplasms, Squamous Cell | Skin Neoplasms | Neoplasms, Basal Cell

United States
University Hospital Schleswig-Holstein

Completed

Definitive Radiochemotherapy Plus/Minus Cetuximab in Unresectable Locally Advanced Esophageal Cancer

Esophageal Cancer

Germany
Celgene

Completed

Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Carcinoma, Squamous Cell of Head and Neck

United States
M.D. Anderson Cancer Center
Sanofi

Completed

Oxaliplatin-Based Chemotherapy and Chemoradiotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Carcinoma

Esophageal Cancer | Gastroesophageal Cancer

United States
Daniela Kandioler
Medical University of Vienna; Austrian Society Of Surgical Oncology

Completed

p53-Adjusted Neoadjuvant Chemotherapy for Potentially Resectable Esophageal Cancer (PANCHO)

Esophageal Cancer

Austria
Cliniques universitaires Saint-Luc- Université...
Grand Hôpital de Charleroi

Terminated

Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors

Metastatic Colorectal Cancer

Belgium
National Cancer Institute (NCI)

Completed

Radiotherapy Combined With Oxaliplatin and Fluorouracil Followed By Gemcitabine in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
University of Michigan
Bausch Health Americas, Inc.

Completed

The Effect of Efudex Treatment on Photoaged Skin

Keratosis | Photo-aging

United States
Sun Yat-sen University

Recruiting

Hepatic Arterial Infusion of Raltetrexed With Oxaliplatin(SALOX) Versus FOLFOX in Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
GERCOR - Multidisciplinary Oncology Cooperative...
OSE Immunotherapeutics

Recruiting

Maintenance With OSE2101 Plus FOLFIRI, or FOLFIRI After FOLFIRINOX-based Induction Therapy in Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (TEDOPAM)

Metastatic Cancer | Pancreatic Ductal Adenocarcinoma | Locally Advanced Cancer

France
Eastern Hepatobiliary Surgery Hospital

Unknown

Effect of Intraoperative Controlled Release 5-Fluorouracil Therapy on Recurrence in Hepatocellular Carcinoma Patients

Recurrence | Hepatocellular Carcinoma

China
Merck Sharp & Dohme LLC
Array BioPharma

Completed

Safety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651)

Metastatic Colorectal Cancer

United States, Canada
Institut Cancerologie de l'Ouest

Completed

Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancer (PAMELA70)

Toxicity | Pancreatic Metastatic Cancer

France
University of Erlangen-Nürnberg Medical School

Recruiting

Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer (HyRec)

Rectal Cancer

Germany
Health Science Center of Xi'an Jiaotong University

Completed

Perioperative Vs. Preoperative Chemotherapy With Surgery in the Squamous Carcinoma of Esophagus

Squamous Carcinoma of Esophagus | Esophagus Disorders

China
University Hospital of Crete

Terminated

Lohp, 5-Fu/Lv and Bevacizumab, Alternative With Cpt-11, 5-Fu/Lv and Cetuximab In Metastatic Crc

Colorectal Cancer

Greece
Carilion Clinic

Recruiting

Combination 5-FU / Calcipotriene Cream for SCCIS/SCC

Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
Eli Lilly and Company

Completed

A Study in Head and Neck Cancer

Head and Neck Cancer

Mexico, United States, Canada
Sun Yat-sen University

Unknown

A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC

Gastrointestinal Neoplasms | Digestive System Neoplasms | Neoplasm Metastasis | Colorectal Neoplasms | Intestinal Neoplasms

China
AbbVie

Terminated

A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab

Cancer

United States, Belgium, Canada, Korea, Republic of, Spain, Taiwan
University of Virginia
Danisco Sweeteners Oy

Completed

Effect of Probiotic on Rhinovirus Induced Colds (MK EPRIC)

Common Cold
University College Cork
European Commission

Unknown

Probiotics in GastroIntestinal Disorders (PROGID)

Crohn's Disease | Ulcerative Colitis

Ireland
Federation Francophone de Cancerologie Digestive

Completed

Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

Colorectal Cancer
Robert Roessle Klinik
Federation Francophone de Cancerologie Digestive; European Organisation for... and other collaborators

Completed

High-Dose Fluorouracil With or Without Leucovorin Compared With Standard Fluorouracil Plus Leucovorin Following Surgery in Treating Patients With Stage III Colon Cancer

Colorectal Cancer

France, Spain, Belgium, Netherlands, Serbia, Germany
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Colorectal Cancer

United States

Search clinical trials for: 5-fluorouracil/leucovorin

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