Search clinical trials for: A group

Total 20242 results

Novartis Pharmaceuticals

Recruiting

Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS (STHENOS)

Multiple Sclerosis

Germany, Spain, Italy, France, United Kingdom
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom
Bispebjerg Hospital
Odense University Hospital; Zealand University Hospital; Hvidovre University... and other collaborators

Recruiting

Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction (DANBLOCK)

ST Elevation Myocardial Infarction | Acute Myocardial Infarction | Non-ST Elevation Myocardial Infarction (nSTEMI)

Denmark
Eli Lilly and Company

Active, not recruiting

A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

Breast Neoplasms

United States
National Cancer Institute (NCI)

Active, not recruiting

Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs

Extensive Stage Lung Small Cell Carcinoma | Limited Stage Lung Small Cell Carcinoma | Platinum-Resistant Lung Small Cell Carcinoma | Platinum-Sensitive Lung Small Cell Carcinoma | Bladder Small Cell Neuroendocrine Carcinoma | Extrapulmonary Small Cell Neuroendocrine Carcinoma | Recurrent Lung... and other conditions

United States
University of British Columbia
University of Manitoba; The Hospital for Sick Children; McGill University Health... and other collaborators

Active, not recruiting

The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis (OPT-JIA)

Juvenile Idiopathic Arthritis

Canada
Ipsen

Terminated

Study to Evaluate the Safety and Preliminary Efficacy of 177Lu-OPS201 in NETs

Neuroendocrine Tumors

United States, Australia, Austria, Canada, Denmark, France, Switzerland, United Kingdom
Assistance Publique - Hôpitaux de Paris

Completed

Treatment of Familiar Lymphohistiocytosis (C-HLH)

Hemophagocytic Lymphohistiocytosis (HLH)

France
Cairo University

Unknown

Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression

Symptomatic Irreversible Pulpitis
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

Methylprednisolone Sodium Succinate in Treating Patients With Acute Graft-versus-Host Disease of the Gastrointestinal Tract

Acute Graft Versus Host Disease | Intestinal Graft Versus Host Disease

United States
Everett Meyer
Doris Duke Charitable Foundation

Terminated

Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells

Chronic Lymphocytic Leukemia (CLL) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Leukemia, Acute | Chronic Myelogenous Leukemia (CML) | Non-Hodgkin Lymphoma (NHL)

United States
Masonic Cancer Center, University of Minnesota

Completed

Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders

Mucopolysaccharidosis | Hurler Syndrome | Sphingolipidoses | Peroxisomal Disorders | Krabbe Disease | Adrenoleukodystrophy (ALD) | Hunter Syndrome | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Metachromatic Leukodystrophy (MLD) | Maroteaux-Lamy Syndrome

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Celgene; Schering-Plough

Completed

Thalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignant Glioma

Brain and Central Nervous System Tumors

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Terminated

IPI Biochemotherapy for Chemonaive Patients With Metastatic Melanoma

Melanoma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Indiana University

Completed

Expressive Writing and Adjustment to Metastatic Breast Cancer

Metastatic Breast Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Symptom Burden in Head and Neck Cancer

Head And Neck Cancer

United States
Novartis Pharmaceuticals

Completed

Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients

Renal Function

Denmark, Norway, Sweden
Janssen Research & Development, LLC

Completed

A Study to Assess the Relative Bioavailability of 4 Formulations of Fentanyl Transdermal System Compared Against DUROGESIC Fentanyl Transdermal Patch After Single Application in Healthy Volunteers

Healthy

Belgium
Sanofi

Completed

Long Term Safety of Teriflunomide When Added to Interferon-Beta or Glatiramer Acetate in Patients With Multiple Sclerosis

Multiple Sclerosis

United States, Canada, Germany, Italy, Spain, United Kingdom, Austria
McNeil AB

Completed

To Test Bioequivalence Between Two Formulations of Paracetamol/Phenylephrine

Respiratory Tract Infections

Ireland
AstraZeneca

Completed

Budesonide / Formoterol in Treatment of Exacerbations of COPD

Chronic Obstructive Pulmonary Disease

Netherlands
Chonbuk National University Hospital

Completed

Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer

Normal Volunteers

Korea, Republic of
AstraZeneca

Completed

Atlantis Symbicort

Asthma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms

China
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
Hamad Medical Corporation

Recruiting

Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.

Bronchial Asthma

Qatar
Johns Hopkins University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Optimizing Treatment to Improve TBM Outcomes in Children (TBM-KIDS)

Tuberculosis, Meningeal

India, Malawi
Imam Abdulrahman Bin Faisal University

Completed

Effect of a Vibration System on Pain Reduction During Injection of Local Dental Anaesthesia in Children

Dental Anxiety | Local Anaesthetic

Saudi Arabia
University of Oxford

Completed

A Study of the Interaction Between BCG And MenC Immunisation: BAM (BAM)

Immune Response | BCG Infection | Reaction - Vaccine

United Kingdom
Satheesh Elangovan

Withdrawn

Pre-Emptive Analgesia in Dental Implant Surgery

Pain, Postoperative

United States
Avanir Pharmaceuticals

Terminated

Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)

Pseudobulbar Affect (Involuntary Laughing and/or Crying)

United States
Rigshospitalet, Denmark
Lundbeck Foundation

Completed

Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty

Hyperalgesia | Knee Joint Osteoarthrosis | Severe Movement Related Pain

Denmark
US Department of Veterans Affairs
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy (RACAT)

Rheumatoid Arthritis

United States, Canada
German CML Study Group

Unknown

Chemotherapy, Interferon, and Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia

Leukemia

Germany
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases

United States
NSABP Foundation Inc
National Cancer Institute (NCI)

Completed

Octreotide, Tamoxifen, and Chemotherapy in Treating Women With Breast Cancer

Breast Cancer

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care

HIV Infections

United States
Bristol-Myers Squibb

Completed

Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected Patients

HIV Infections

United States, United Kingdom
Boehringer Ingelheim

Completed

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Healthy
NeuroRx, Inc.

Not yet recruiting

NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis

Urinary Tract Infections | Pyelonephritis
AstraZeneca

Recruiting

A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD). (ATHLOS)

Chronic Obstructive Pulmonary Disease

Germany, Spain, United States, China, Korea, Republic of, Argentina, United Kingdom, Canada
Wake Forest University Health Sciences

Recruiting

The Effects of Sedatives on Tobacco Use Disorder Version 2 (SED-TUD2)

Tobacco Smoking

United States
Hip Innovation Technology

Recruiting

Safety and Effectiveness of the HIT Reverse HRS

Osteoarthritis, Hip | Avascular Necrosis of Hip | Degenerative Joint Disease | Traumatic Arthropathy-Hip

United States
Blokhin's Russian Cancer Research Center

Recruiting

Analysis of Therapy Sequence in Women With HR+, HER2 - mBC in Moscow: A Multicenter Retrospective Observational Study.

Breast Cancer Stage IV

Russian Federation
Dana-Farber Cancer Institute
Genentech, Inc.

Recruiting

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Breast Cancer | Invasive Carcinoma of the Breast | Node Negative Breast Cancer | Micrometastasis Breast Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Ipilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Emory University

Enrolling by invitation

Post-operative Methylprednisolone Taper Course for Orthopedic Surgery

Orthopedic Surgeries

United States
BioLineRx, Ltd.

Completed

Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome

Aplastic Anemia | Hypoplastic Myelodysplastic Syndrome

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Image-Guided Stereotactic Biopsy of High Grade Gliomas

Glioma | Brain Cancer

United States
National University Hospital, Singapore

Completed

Study Evaluating Two Loading Regimens of Sunitinib or Bevacizumab Alternating With Cisplatin and Gemcitabine as Induction Therapy for Locally Advanced Nasopharyngeal Carcinoma (NPC)

Nasopharyngeal Carcinoma

Singapore

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