Search clinical trials for: ABBV-838

Total 948 results

National Cancer Institute (NCI)

Completed

Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Stage IV Fallopian Tube Cancer AJCC v6 and v7 | Stage IV Ovarian Cancer AJCC v6 and v7 | Stage IV Primary Peritoneal Cancer AJCC v7

United States
National Cancer Institute (NCI)

Completed

Veliparib With or Without Mitomycin C in Treating Patients With Metastatic, Unresectable, or Recurrent Solid Tumors

Solid Neoplasm

United States
zr Pharma & GmbH
Bristol-Myers Squibb; Foundation Medicine

Terminated

A Study to Evaluate Rucaparib in Combination With Nivolumab in Patients With Selected Solid Tumors (ARIES)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Endometrioid Adenocarcinoma | High Grade Serous Carcinoma | Primary Peritoneal Carcinoma

United States
Takeda

Completed

TAK-438_110 Drug Interaction With Cytochrome P450 3A4 (CYP3A4) Inhibitor Clarithromycin

Healthy Volunteers
University of Alabama at Birmingham

Terminated

CB-839 in Combination With Niraparib in Platinum Resistant BRCA -Wild-type Ovarian Cancer Patients (BRCA)

Ovarian Cancer | Resistant BRCA Wild-Type Ovarian Cancer

United States
AbbVie

Recruiting

A Study to Assess the Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma Receiving Oral ABBV-453 Tablets

Relapsed/Refractory Multiple Myeloma

United States, Australia, Israel, United Kingdom
National Cancer Institute (NCI)

Completed

Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer

Hereditary Breast and Ovarian Cancer Syndrome | Adult Solid Neoplasm | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier

United States
Steven J Isakoff, MD, PhD
Dana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; Abbott

Active, not recruiting

ABT-888 and Temozolomide for Metastatic Breast Cancer and BRCA1/2 Breast Cancer

Breast Cancer | Metastatic Breast Cancer | BRCA1 Gene Mutation | brca2 Gene Mutation

United States
Takeda

Completed

Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)

Healthy Volunteers

Japan
University of Alabama at Birmingham
GlaxoSmithKline; AbbVie; Breast Cancer Research Foundation of Alabama

Active, not recruiting

Pilot Study of Veliparib (ABT-888) and Lapatinib (Tykerb) in Patients With Metastatic, Triple Negative Breast Cancer

Metastatic Triple Negative Breast Cancer

United States
pharmaand GmbH

Terminated

A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes (LODESTAR)

Solid Tumor

United States
Calithera Biosciences, Inc

Terminated

Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors

Clear Cell Renal Cell Carcinoma | Colorectal Cancer | Solid Tumor | CRC | TNBC - Triple-Negative Breast Cancer | ccRCC | RCC

United States
National Cancer Institute (NCI)
Abbott

Active, not recruiting

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Liver Failure | Melanoma | Renal Failure | Breast Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Lung Carcinoma | Ovarian Carcinoma | Esophageal Carcinoma | Metastatic Malignant Neoplasm | Unresectable Malignant Neoplasm | Malignant Head and Neck Neoplasm | Carcinoma of Unknown Primary | Malignant Testicular...

United States
National Cancer Institute (NCI)

Active, not recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

Acute Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders

Hematopoietic and Lymphoid Cell Neoplasm | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Adult Acute Lymphoblastic Leukemia | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic... and other conditions

United States
National Cancer Institute (NCI)

Completed

Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

Recurrent Small Cell Lung Carcinoma

United States
National Cancer Institute (NCI)

Completed

Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Adult Solid Neoplasm

United States
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Sertraline 100 mg Tablet and ZOLOFT Following a 100 mg Dose in Healthy Subjects Under Fed Conditions

Healthy

Canada
University of Hohenheim
University Hospital Tuebingen

Completed

Physical Activity and Protein Supplementation After Bariatric Surgery (PAPAB) (PAPAB)

Bariatric Surgery Candidate

Germany
AbbVie (prior sponsor, Abbott)

Completed

A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma

Melanoma | Skin Cancer | Metastatic Melanoma
Northwestern University
Novartis

Terminated

Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation

Prostate Cancer | Osteoporosis

United States
Calithera Biosciences, Inc
Novotech (Australia) Pty Limited

Completed

Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects

Drug Interaction

Australia
AbbVie

Completed

Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Australia, Belgium, Canada, Czechia, France, Hungary, Korea, Republic of, Netherlands, Romania, Russian Federation, Spain
Abbott

Completed

A Study of Leuprolide 11.25 mg and 30 mg Administered Every 3 Months to Treat Central Precocious Puberty

Puberty, Precocious

United States, Puerto Rico
National Cancer Institute (NCI)

Withdrawn

ABT-888, Carboplatin, and Paclitaxel for Cancer With Liver or Kidney Problems

Neoplasms

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Completed

Liposomal Doxorubicin and PSC 833 in Treating Patients With AIDS-Related Kaposi's Sarcoma or Other Advanced Cancers

Sarcoma | Unspecified Adult Solid Tumor, Protocol Specific

United States
Advantage Silver Dental Arrest, LLC
University of Washington

Completed

Pharmacokinetics of Advantage Arrest

Dental Caries

United States
AbbVie

Recruiting

Study Assessing Activity of Intravenous (IV) ABBV-383 Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

Israel, Taiwan
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Unresectable Metastatic Colorectal Cancer

Israel, United States, Japan, Korea, Republic of, Taiwan
Bayer

Active, not recruiting

Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

Prostatic Neoplasms, Castration-Resistant

Japan
Advantage Silver Dental Arrest, LLC
University of Washington

Active, not recruiting

Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age

Dental Caries in Children

United States
Roseman University of Health Sciences

Completed

Silver Diamine Fluoride Treatment of Active Root Caries Lesions in Older Adults: A Case Series

Root Caries
Federal University of Uberlandia
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Fundação de Amparo...

Completed

Effectiveness of Office Bleaching Agents in Patients of Different Age Group

Satisfaction

Brazil
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Glioblastoma | Gliosarcoma

United States, Puerto Rico
Stephanie Shimizu
University of Southern California

Recruiting

Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride

Dental Caries in Children | Dental Caries | Dental Caries Class II

United States
AbbVie (prior sponsor, Abbott)

Completed

A Clinical Study Conducted in Multiple Centers Comparing Veliparib in Combination With Carboplatin and Paclitaxel Versus a Placebo in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer

Non-Small -Cell Lung Cancer
URAL Telekomunikasyon San. Trade Inc.

Completed

Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus Images

Glaucoma | Eye Diseases | Age-Related Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Retinal Vein Occlusion

Turkey
Dongyang People's Hospital

Not yet recruiting

Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain

Myopia

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Melanoma of Unknown Primary | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Recurrent Cutaneous Melanoma | Metastatic Malignant Neoplasm in Lymph Node

United States
National Cancer Institute (NCI)

Completed

Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer

Neuroendocrine Carcinoma | Small Cell Carcinoma | Extensive Stage Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Large Cell Lung Carcinoma

United States
AbbVie

Completed

A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

Metastatic Breast Cancer

United States, Argentina, Australia, Austria, Belarus, Belgium, Canada, Chile, Colombia, Czechia, Denmark, Estonia, Finland, France, Germany, Hungary, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Mexico, Netherlands, Norway, Po... and more
Millennium Pharmaceuticals, Inc.

Completed

A Phase 2 Study to Evaluate the Safety and Efficacy of TAK-385, Together With a Leuprorelin Observational Cohort, in Participants With Prostate Cancer

Prostate Cancer

United States, Canada
Imperial College London
Organon

Completed

Testosterone and Myocardial Perfusion in Coronary Heart Disease (CHD)

Coronary Heart Disease

United Kingdom
Takeda

Completed

Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin

Gastric Ulcers | Duodenal Ulcers

Japan
Takeda

Completed

Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin

Gastric Ulcers | Duodenal Ulcers

Japan
University Children Hospital Homburg
University Hospital Tuebingen

Unknown

Laser Acupuncture Against Nausea in Children

Cancer | Nausea | Vomiting

Germany
General and Maternity Hospital of Athens Elena...

Unknown

Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anaesthetic Management.

Covid-19 | Anesthesia | Maternal Psychological Distress

Greece
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

Docetaxel With or Without PI-88 in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Lung Cancer

Australia
pharmaand GmbH
Gilead Sciences

Terminated

A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR)

Ovarian Cancer | Solid Tumor | Urothelial Carcinoma | Triple-negative Breast Cancer

United States
University of Cambridge
GE Healthcare; Public Health England; Cancer Research UK; Queen Mary University...

Recruiting

Breast Screening - Risk Adaptive Imaging for Density (BRAID)

Breast Cancer

United Kingdom

Search clinical trials for: ABBV-838

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