Search clinical trials for: ACT-453859 800 mg

Total 3340 results

Novartis Pharmaceuticals

Completed

Efficacy and Safety of Subcutaneous Secukinumab in Adults With Moderate to Severe Scalp Psoriasis (SCALP)

Chronic Scalp Psoriasis

United States
Belfast Health and Social Care Trust

Completed

Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty (TRAC-24)

Primary Total Hip Arthroplasty | Primary Total Knee Arthroplasty

United Kingdom
Janssen Pharmaceutical K.K.

Completed

An Efficacy and Safety of CNTO 1959 (Guselkumab) in Participants With Moderate to Severe Plaque-type Psoriasis

Psoriasis

Japan
University Hospital, Caen
Merck Sharp & Dohme LLC

Not yet recruiting

DOR/TDF/3TC Switch With M184V/I in People With Controlled HIV (Drive Off-Road) (DOR)

Hiv

France
Fundacion Espanola para la Curacion de la Leucemia...
Pfizer; Roche Farma, S.A

Terminated

Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients

Chronic Phase-Chronic Myeloid Leukemia

Spain
Janssen Research & Development, LLC

Completed

A Phase II Study of Bermekimab (MABp1) in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
Meda Pharmaceuticals

Completed

Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back

Lower Back Pain

United States
NeuroBo Pharmaceuticals Inc.

Completed

Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

Hypercholesteremia
San Gerardo Hospital

Completed

Impact of Intraperitonael Nebulization of Local Anesthetic on Postoperative Pain Associated With Laparoscopic Surgery

Gynecologic Laparoscopic Surgery

Italy
Universidade Estadual Paulista Júlio de Mesquita...

Completed

Acute Influence of Resveratrol Supplementation and Beet Extract in Recovery After Exercise in Coronary Paths

Coronary Artery Disease | Blood Pressure | Heart Rate | Autonomic Nervous System Disease

Brazil
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Rhodes Pharmaceuticals, L.P.
Purdue Pharma LP

Completed

PRC-063 in an ADULT Workplace Environment

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Pharmacodynamic Study of Once-Daily and Twice-Daily Dosing With Canagliflozin in Healthy Adult Volunteers

Healthy
Bayer

Completed

Continuous Dosing of BAY73-4506 in Patients With Advanced Malignancies

Neoplasm

United States
Teva Pharmaceuticals USA

Completed

Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting

Healthy

Canada
Transposon Therapeutics, Inc.

Active, not recruiting

A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD

Amyotrophic Lateral Sclerosis | Frontotemporal Dementia

Spain, United States, Belgium, France, Germany
Galapagos NV

Completed

Study to Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of GLPG1690 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom, Ukraine
Sprout Pharmaceuticals, Inc

Completed

Pharmacokinetics of Flibanserin in Postmenopausal Women With Hypoactive Sexual Desire Disorder (HSDD)

Sexual Dysfunctions, Psychological

United States
DSM Nutritional Products, Inc.

Completed

Effects of cogniVida™ on Learning and Memory and in Comparison to Placebo After Long-term Supplementation (MemIprov)

Healthy

United Kingdom
Southern Illinois Healthcare Foundation
Janssen Scientific Affairs, LLC

Completed

A Retrospective Study to Evaluate the Safety and Efficacy of a Nucleoside-Sparing Regimen of Darunavir, Ritonavir, and Dolutegravir

HIV-1-infection
University of California, San Diego

Recruiting

Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (PNLABXPART2)

Sepsis | Nephrolithiasis | Urinary Tract Infection (UTI)

United States
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
Cytokinetics
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis

Myasthenia Gravis

United States
Rigel Pharmaceuticals

No longer available

Expanded Access of Fostamatinib in Patients With Persistent or Chronic Relapsing/Refractory ITP

Immune Thrombocytopenic Purpura
Zero Point Five Therapeutics

Not yet recruiting

Phase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676 for the Treatment of Soil Transmitted Helminthiasis (STH)

Soil-Transmitted Helminthiasis (STH)

Brazil, Ghana
Altavant Sciences GmbH
Covance; Altavant Sciences, Inc.

Completed

Pharmacokinetics and Excretion of Oral [14C]-Rodatristat Ethyl

Healthy

United States
Galapagos NV

Completed

Investigation of the Pharmacokinetics and Metabolism of GLPG0634 in Healthy Male Subjects

Healthy

United Kingdom
Novartis

Completed

Efficacy of DNK333 in Patients With COPD and Cough

Chronic Obstructive Pulmonary Disease

United Kingdom, Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational Study (MEPOREAL)

Chronic Rhinosinusitis With Nasal Polyps

Italy
Bial - Portela C S.A.

Completed

Absorption, Distribution, Metabolism and Excretion of [14C] Labelled BIA 5-1058

Cardiovascular Diseases

United Kingdom
Pfizer

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Glasdegib

Hepatic Impairment

United States
Aquinox Pharmaceuticals (Canada) Inc.

Terminated

Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Canada, United States
Merck Sharp & Dohme LLC

Completed

MK3207 for Treatment of Acute Migraines (3207-005)

Migraine
Amneal Pharmaceuticals, LLC
Symbio, LLC

Completed

Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)

Uncomplicated Urinary Tract Infections

United States
Teva Pharmaceuticals USA

Completed

5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Fasting

Healthy

United States
Supernus Pharmaceuticals, Inc.

Completed

Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 2)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
TaiGen Biotechnology Co., Ltd.
QPS-Qualitix; R&G Pharma Studies Co.,Ltd.

Completed

Study to Evaluate the Efficacy and Safety of Intravenous Infusion With Nemonoxacin Malate Sodium Chloride

Pneumonia

Taiwan, China
University of Geneva, Switzerland
University of Lausanne

Recruiting

Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies (AMA)

Periodontal Diseases | Pharmacokinetics | Antibiotics

Switzerland
Shiraz University of Medical Sciences

Completed

Dose-related Effect of Aspirin on Laboratory-defined Acetylsalicylic Acid Resistance and Clinical Outcome After Coronary Stenting

Coronary Stenting

Iran, Islamic Republic of
Supernus Pharmaceuticals, Inc.

Completed

Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 1)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Eisai Limited

Terminated

A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures

Epilepsy

United Kingdom, Germany, Hungary, Switzerland, Italy, Netherlands, Poland
Thai Red Cross AIDS Research Centre

Recruiting

Assessment of Drug-drug Interactions Between Masculinizing Hormone Therapy and Antiretroviral Agents Concomitantly for Pre-exposure Prophylaxis Among Transgender Men

Drug Interaction

Thailand
Bayer

Recruiting

Darolutamide + Androgen Deprivation Therapy (ADT) in Chinese Men With High Risk, Nonmetastatic Prostate Cancer

Prostate Cancer

China
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise

Diabetes Mellitus, Type 2

United States, Ukraine, Argentina, Mexico, Romania, South Africa, Korea, Republic of, Russian Federation, Brazil, Puerto Rico, Hungary, Slovakia, Czechia
Kartal Kosuyolu Yuksek Ihtisas Education and Research...

Unknown

Anticoagulation Regiments in Patients With Prosthetic Heart Valve Thrombosis

Thrombosis

Turkey
Ipsen

Recruiting

A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis. (ELMWOOD)

Primary Sclerosing Cholangitis

United States, Spain, Germany, Canada, United Kingdom, Italy, Portugal
University of Turin, Italy

Withdrawn

Pharmacokinetics of Maraviroc and Boosted Atazanavir Dual Regimen in Stable HIV-infected Patients

HIV Infection

Italy
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)

Malaria

United Kingdom
Teva Pharmaceuticals USA

Completed

5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Non-Fasting

Healthy

United States
Mansoura Integrated Fertility Center

Completed

Is Adding E2 to P4 Luteal Support In High Responder Long Gn-RH Agonist ICSI Cycles Detrimental to Outcome? RCT

Infertility | IVF

Egypt

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