Search clinical trials for: AFN-12520000

Total 2200 results

Alnylam Pharmaceuticals

Completed

Phase 2 Study to Evaluate ALN-TTRSC (Revusiran) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

TTR-mediated Amyloidosis

United States, United Kingdom
Thuasne
University Hospital of Saint-Etienne

Completed

Comparison of Thermo-plastic Versus Carbon Foot Ankle Orthosis to Improve Gait and Reduce Fatigue in Post-stroke Patients: a Biomechanical and Neurophysiological Study (MECASPRY)

Gait, Hemiplegic | Hemiparesis;Poststroke/CVA

France
Allergan

Completed

Efficacy, Safety, and Tolerability of Multiple Dosing Regimens of Oral Atogepant (AGN-241689) in Episodic Migraine Prevention

Migraine, With or Without Aura

United States
NovaShunt AG

Completed

The Automated Fluid Shunt (AFS)in Chronic Congestive Heart Failure

Ascites | Congestive Heart Failure

Sweden
Vertex Pharmaceuticals Incorporated

Completed

Trial of AVN-944 in Patients With Advanced Hematologic Malignancies

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Waldenstrom's Macroglobulinemia | Acute Leukemia | Chronic Leukemia

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Increasing Treatment Adherence in Co-Occurring Psychiatric and Drug Use Disorders

Drug Use Disorders | Psychiatric Diagnosis | Diagnosis, Dual (Psychiatry)

United States
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse... and other collaborators

Completed

Immunologic Memory (Supp. of ATN 024)

HIV Infections

United States
Alnylam Pharmaceuticals

Terminated

A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

Gout

United Kingdom
AbbVie

Active, not recruiting

A Study to Assess Adverse Events and Effectiveness of Intradermally Injected JUVÉDERM® VOLITE™ Gel Filler in Adult Participants in China With Fine Lines Around the Mouth

Perioral Lines

China
Institut Paoli-Calmettes
Janssen-Cilag Ltd.

Unknown

Active Surveillance With or Without Apalutamide Treatment in Low Risk Prostate Cancer (PC-ARN)

Low Risk Prostate Cancer

France
Alnylam Pharmaceuticals

Completed

A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects

Transthyretin-mediated Amyloidosis (ATTR Amyloidosis)

United Kingdom
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment

Solid Tumors

United States, Spain
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
APRINOIA Therapeutics, LLC

Active, not recruiting

Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects

Healthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's Disease

United States
Szpitale Pomorskie Sp. z o. o.

Unknown

Atrial Flow Regulator in Heart Failure (PROLONGER)

Congestive Heart Failure

Poland
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Vanderbilt University

Completed

Improving Hospitalizations for Children With ASD

Autism Spectrum Disorder | Autistic Disorder

United States
Hill-Rom

Completed

Air Fluidized Therapy (AFT) in Patients With Suspected Deep Tissue Injury (sDTI)

Pressure Ulcers

United States
Allergan

Completed

Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution

Ocular Hypertension | Glaucoma, Open-Angle

United States
AbbVie

Recruiting

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism

United States
University of Ottawa

Recruiting

Efficacy of Ceiling Fans for Mitigating Thermal Strain During Bed Rest in Older Adults During Heat Waves

Hyperthermia | Aging | Heat Stress | Cooling

Canada
Hospices Civils de Lyon

Recruiting

Respiferon Project (Respiferon)

Respiratory Viral Infection

France
AbbVie

Recruiting

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine (Kaleidoscope)

Episodic Migraine

United States, Puerto Rico, Spain, Canada, Netherlands, Israel, Sweden, Poland, Hungary, France, Denmark, Japan, United Kingdom, Italy, Romania, Belgium
APRINOIA Therapeutics

Recruiting

[18F]APN-1607 PET in Subjects With AD Compared to HC

Healthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's Disease

China
M.D. Anderson Cancer Center

Recruiting

First-in-Human Assessment of Safety, Biodistribution and Pharmacokinetics of 18F-Fluoro-1-Naphthol (18F-4FN) for PET Imaging

Endocrine Neoplasia

United States
AbbVie

Completed

Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Adult Participants Undergoing Open-chest Cardiac Surgery (NOVA)

Post-Operative Atrial Fibrillation

United States, Austria, Canada, Germany, Italy, Netherlands, Spain, Sweden, United Kingdom
AbbVie

Active, not recruiting

A Study to Assess Adverse Events and Effectiveness of Injected JUVÉDERM® VOLITE™ Gel Filler for Change in Neck Lines in Adult Chinese Participants

Neck Lines

China
DePuy Orthopaedics

Completed

DePuy Trochanteric (ATN) Nailing Clinical Outcomes Trial (ATN)

Femoral Fracture (Proximal)

United States
Cook Group Incorporated

Completed

Surgisis Anal Fistula Plug Study: An Experience in Saudi Arabia (SurgiSIS AFP)

Anal Fistula

Saudi Arabia
Alnylam Pharmaceuticals

Completed

Dose Escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ALN-VSP02 In Patients With Advanced Solid Tumors With Liver Involvement

Solid Tumors

United States, Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Apalutamide in Treating Patients With Prostate Cancer Before Radical Prostatectomy

Prostate Adenocarcinoma | Stage IIB Prostate Cancer AJCC v8

United States
Regeneron Pharmaceuticals

Recruiting

A Study to Examine the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Adult Patients With Symptomatic Generalized Myasthenia Gravis (NIMBLE)

Generalized Myasthenia Gravis

Korea, Republic of, Japan, Spain, United States, Germany, Italy, Canada, Georgia, India, Belgium, Poland, Taiwan, Australia, Denmark, France, Turkey, Serbia, United Kingdom, Czechia
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Allergan

Completed

A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance in Participants, 40 to 55 Years of Age (TAURUS)

Presbyopia

Australia
Mayo Clinic

Completed

Stem Cell Coated Fistula Plug in Patients With Crohn's RVF

Crohn Disease | Fistula Vagina

United States
William A. Faubion, M.D.

Completed

Re-treatment From a Phase I Study of MSC-AFP in Patients With Perianal Fistulas (MSC-AFP)

Perianal Fistula | Cryptoglandular Perianal Fistula | Crohn's Perianal Fistula

United States
Alnylam Pharmaceuticals

Completed

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

ATTR Amyloidosis | Transthyretin (TTR)-Mediated Amyloidosis | Familial Amyloidotic Polyneuropathy (FAP) | Familial Amyloid Neuropathies

France, Germany, Portugal, United Kingdom, Sweden, Spain
Allergan

Completed

AGN-229666 Ophthalmic Solution for the Treatment of Seasonal or Perennial Allergic Conjunctivitis

Conjunctivitis, Allergic

Japan
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor

Nonalcoholic Steatohepatitis (NASH) | Nonalcoholic Fatty Liver Disease (NAFLD) | Genetic Risk Factor
Alnylam Pharmaceuticals

Active, not recruiting

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, Brazil, Bulgaria, France, Italy, Japan, Mexico, Netherlands, Taiwan, United Kingdom, Belgium, Czechia, Denmark, New Zealand, Sweden, Korea, Republic of, Argentina, Chile, Hong Kong, Portugal
Alnylam Pharmaceuticals

Terminated

A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis | NASH

United States, Bulgaria, United Kingdom, Belgium, Turkey
Alnylam Pharmaceuticals

Completed

The Study of ALN-TTR02 (Patisiran) for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)

TTR-mediated Amyloidosis

Portugal, Sweden, Brazil, United States, France, Spain, Germany
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Alnylam Pharmaceuticals

Terminated

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

IgA Nephropathy (IgAN) | Berger Disease | Glomerulonephritis, IgA

Canada, Malaysia, France, Sweden, United Kingdom, Philippines, Singapore, Spain, Taiwan
Mayo Clinic

Completed

Stem Cell Fistula Plug in Cryptoglandular Perianal Fistulas (MSC-AFP)

Perianal Fistula | Cryptoglandular Perianal Fistula

United States
Jian-Kun Hu
West China Hospital

Unknown

Effect of Obesity on Surgical Outcomes and Survival for Gastric Cancer

Obesity | Gastric Cancer

China

Search clinical trials for: AFN-12520000

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