Search clinical trials for: AL-034

Total 1144 results

FORUM Pharmaceuticals Inc

Unknown

Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Granulin Mutation

Belgium, United States, France, Italy, Netherlands, United Kingdom
Kwang Dong Pharmaceutical co., ltd.

Completed

A Phase 2 Study to Compare the Efficacy and Tolerability of Tarafenacin 0.2 mg and Tarafenacin 0.4 mg to Placebo in Patients Suffering From Overactive Bladder.

Overactive Bladder

Korea, Republic of
Sunesis Pharmaceuticals

Completed

Safety Assessment of One-hour Infusions of SNS-032 for the Treatment of Select Advanced Solid Tumors

Tumors

United States
GTx

Withdrawn

Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass

ER+ and AR+ Breast Cancer

United States
Tetraphase Pharmaceuticals, Inc.

Completed

A Safety and PK Study of IV Eravacycline

Bacterial Infections

United States
University of North Carolina, Chapel Hill

Completed

Analysis of Orthodontic Tooth Movement Using 3D Imaging

Malocclusion | Tooth Crowding | Dental Crowding

United States
Chung-Ang University Hosptial, Chung-Ang University...

Unknown

Study of Stroke Volume Variation and Pleth Variability Index as Predictors of Fluid Responsiveness

Thyroidectomy | Fluid Responsiveness

Korea, Republic of
Sen-Jam Pharmaceutical

Completed

Safety and Efficacy of a Combination Product for the Prevention of Veisalgia

Veisalgia
GlaxoSmithKline

Completed

Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (GSK580299) in Healthy Female Subjects 10-25 Years of Age.

Human Papillomavirus (HPV) Infection

Senegal, Tanzania
Janssen Research & Development, LLC

Withdrawn

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function

Hepatic Impairment
HealOr
Cato Research; Clinigene International Ltd

Unknown

Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers (Truheal)

Diabetic Foot Ulcer

United States, India
HealOr

Completed

Wound Healing Effects of HO/03/03 In Patients With Diabetic Neuropathic Plantar and Venous Ulcers, Pilot Study.

Diabetic Foot Ulcer | Venous Ulcer

Israel
Zealand University Hospital
University of Copenhagen; Steno Diabetes Center Copenhagen; Holbaek Sygehus

Recruiting

The Danish Childhood Obesity Biobank

Cardiovascular Diseases | Obesity | Metabolic Disease | NAFLD, Non-alcoholic Fatty Liver Disease

Denmark
International Partnership for Microbicides, Inc.

Completed

A Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004, Containing 25 Mg Of Dapivirine

HIV
ACELYRIN Inc.

Completed

A Study to Investigate Efficacy, Tolerability and Safety of ABY-035 in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis

Poland, Hungary, Germany, Belgium, Czechia, Austria, Spain
Codiak BioSciences

Terminated

A Study of exoASO-STAT6 (CDK-004) in Patients With Advanced Hepatocellular Carcinoma (HCC) and Patients With Liver Metastases From EIther Primary Gastric Cancer or Colorectal Cancer (CRC)

Advanced Hepatocellular Carcinoma (HCC) | Gastric Cancer Metastatic to Liver | Colorectal Cancer Metastatic to Liver

United States
C. R. Bard

Completed

Lutonix® Global AV Registry Investigating Lutonix Drug Coated Balloon for Treatment of Native and Synthetic AV Fistulae (AVR)

Arteriovenous Fistula

United Kingdom, Singapore, France, Italy, Germany, Switzerland, Greece, Austria, Poland, Portugal, Saudi Arabia, Taiwan, Turkey
Novartis Pharmaceuticals

Completed

Study of Efficacy of PEAR-004 in Schizophrenia

Schizophrenia

United States
Hvivo
Prep Biopharm Limited

Completed

Study Examining PrEP-001 in Healthy Subjects

Influenza A H3N2

United Kingdom
Taisho Pharmaceutical R&D Inc.

Completed

Safety, Tolerability and Pharmacokinetics of Single Doses of TS-134 in Healthy Volunteers

Healthy Volunteers

United States
GTx

Completed

Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Muscle Wasting

United States
Medtrade
The Clinical Trial Company

Unknown

Safety and Performance of 032-11 Haemostat in Cardiac and Thoracic Aortic Surgery

C.Surgical Procedure; Cardiac | Haemorrhage.

United Kingdom
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
Janssen Research & Development, LLC

Completed

Study to Investigate the Pharmacokinetic Interaction Between 2 Direct Acting Antiviral Agents Odalasvir and AL-335 and Between 3 Direct Acting Antiviral Agents Simeprevir, Odalasvir and AL-335 at Steady State in Healthy Japanese Participants

Healthy

United Kingdom
HealOr

Unknown

Safety and Efficacy Study of HO/03/03 10-40 Micro Grams to Treat Hard to Heal Wounds (H2H)

Hard to Heal Wounds

Israel
Alios Biopharma Inc.
Alexion

Completed

A Study to Evaluate the Effect of ACH-3102 and Simeprevir on AL-335 Pharmacokinetics in Healthy Volunteers

Chronic Hepatitis C

France
Cyrano Therapeutics, Inc.

Recruiting

Study of CYR-064 Versus Placebo in Patients.

Hyposmia

United States
Lotus Clinical Research, LLC
CerSci Therapeutics

Unknown

Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Volunteers

Surgery | Pain, Acute | Acute Pain | Neuropathy

United States
C. R. Bard

Terminated

Lutonix Drug Coated Balloon for Treatment of Femoropopliteal Arteries in United States Females (CONFIRM) (CONFIRM)

Popliteal Artery Stenosis | Popliteal Artery Occlusion | Femoral Artery Occlusion | Femoral Artery Stenosis

United States
BIND Therapeutics

Completed

A Phase 2 Study to Determine the Safety and Efficacy of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension), Administered to Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer | CRPC

United States
BIND Therapeutics

Completed

A Study of BIND-014 Given to Patients With Advanced or Metastatic Cancer

Cancer | Metastatic Cancer | Solid Tumors

United States
Tongji Hospital
The First Affiliated Hospital of Nanchang University; The First Hospital of... and other collaborators

Recruiting

Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia

Liver Failure | Decompensated Cirrhosis | Thrombocytopenia

China
Gilead Sciences
Galapagos NV

Completed

Study to Evaluate the Efficacy and Safety of Filgotinib in the Treatment of Perianal Fistulizing Crohn's Disease (Divergence2)

Fistulizing Crohn's Disease

United States, Italy, Belgium, Austria, Canada, Hungary, United Kingdom, Germany, France
Gilead Sciences
Galapagos NV

Terminated

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Have an Inadequate Response or Are Intolerant to Biologic DMARD Therapy (PENGUIN 2)

Psoriatic Arthritis

Korea, Republic of, United States, Australia, Belgium, Canada, Czechia, Hungary, Japan, Poland, Spain, Taiwan
Gilead Sciences
Galapagos NV

Completed

Study to Evaluate the Efficacy and Safety of Filgotinib in the Treatment of Small Bowel Crohn's Disease (SBCD) (DIVERGENCE 1)

Small Bowel Crohn's Disease

United States, Belgium, United Kingdom, Germany, Spain, Czechia, Canada, Austria, France, Hungary, Italy, Ukraine
BIND Therapeutics

Completed

A Phase 2 Study to Determine the Safety and Efficacy of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension) as Second-line Therapy to Patients With Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

United States, Russian Federation
Theraclone Sciences, Inc.

Unknown

Influenza Virus Challenge Study to Test Monoclonal Antibody TCN-032 as a Treatment for Influenza

Influenza

United Kingdom
Solvay Pharmaceuticals

Completed

Study to Investigate ADME of 14C Labeled SLV334 After an i.v. Infusion

Pharmacology, Clinical

Netherlands
Tetraphase Pharmaceuticals, Inc.
Department of Health and Human Services

Completed

Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women (BAL)

Normal Drug Tolerance

United States
Tetraphase Pharmaceuticals, Inc.

Completed

A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects

Impaired Hepatic Function

United States
Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels

Gout

United States
Samsung Medical Center

Completed

Stroke Volume Variation and Pulse Pressure Variation as Predictors of Fluid Responsiveness During Kidney Transplantation

Kidney Transplantation

Korea, Republic of
National Institute of Allergy and Infectious Diseases...
GlaxoSmithKline; Sanofi Pasteur, a Sanofi Company; HIV Vaccine Trials Network

Completed

Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine (HVTN107)

HIV Infections

South Africa, Mozambique, Zimbabwe
Treatment Research Institute

Completed

CRAFT Behavior Therapy: Treatment Entry Component

Alcohol Dependence | Substance Abuse | Drug Addiction | Opiate Dependence | Stimulant Dependence

United States
Hospital Nacional Homeopático, Mexico
Laboratorio Similia, México

Terminated

Dose-response Study of Carduus Marianus in Centesimal Scale for Dyslipidemia in Climacteric Overweighed or Obese Women.

Obesity | Dyslipidemia | Menopause

Mexico
Alcon Research

Terminated

Open-Label Posterior Juxtascleral Injections of Anecortave Acetate 15mg Dose for Long Term Use in Patients With AMD

Macular Degeneration

United States
Anke Haberkamp

Recruiting

Gamification in the Treatment of Spider Phobia

Spider Phobia

Germany
Phoenix Children's Hospital

Withdrawn

Childhood Alopecia Areata Study Using the 308-nm Excimer Laser

Alopecia Areata

United States
Alcon Research

Completed

A Six-Week Safety Study of an Investigational Ophthalmic Solution

Allergic Conjunctivitis
Alios Biopharma Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of the Combination of AL-335, Odalasvir, and Simeprevir

Chronic Hepatitis C

New Zealand, Moldova, Republic of, Mauritius, United Kingdom

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