Search clinical trials for: AMG 386 Placebo

Total 56475 results

Chosun University Hospital

Completed

Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients (CSUHAPM)

Anesthesia | Elderly Patients | Emergence From Anesthesia | Effects of Dexmedetomidine | Recovery From Anesthesia

Korea, Republic of
University of Minnesota
Pfizer; Minnesota Medical Foundation

Withdrawn

Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial

Tuberculosis | Immune Reconstitution Inflammatory Syndrome | HIV-infection/Aids | Immune Reconstitution Syndrome

Thailand
Xijing Hospital

Unknown

Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events (ADANCE)

Ischemic Stroke | TIA

China
GlaxoSmithKline

Completed

Intravenous And Oral Casopitant (GW679769) For The Prevention Of Chemotherapy Induced Nausea And Vomiting

Nausea | Vomiting | Nausea and Vomiting, Chemotherapy-Induced

United States, Germany, Bulgaria, Hungary, Philippines, Russian Federation, Taiwan, Korea, Republic of, Belgium, Denmark, Hong Kong, Slovakia, South Africa, Spain, Ireland, Latvia, Thailand, Italy, United Kingdom, Argentina, Aus... and more
Royal Brompton & Harefield NHS Foundation Trust
University of Oxford

Unknown

Collaborative Systematic Overview of Randomised Controlled Trials of Beta-Blockers in the Treatment of Heart Failure (BB-META-HF)

Heart Failure

United Kingdom
Pfizer

Completed

A Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Oral Doses Of PF-03716539 In Healthy Adult Subjects

Healthy Volunteers

Belgium
Bristol-Myers Squibb

Terminated

Safety Study of Dasatinib With Bortezomib (Velcade®) and Dexamethasone for Multiple Myeloma

Multiple Myeloma

United States, Italy, France, Spain
Providence Health & Services
Prometheus Laboratories

Active, not recruiting

Comparison of High-dose IL-2 and High-dose IL-2 With Radiation Therapy in Patients With Metastatic Melanoma. (SBRT/IL-2)

Metastatic Melanoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effects of 1592U89 Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Infants and Children

HIV Infections

United States
Aeovian Pharmaceuticals, Inc.

Recruiting

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Healthy Participants

Australia
Rigshospitalet, Denmark

Recruiting

Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac Surgery (GLORIOUS-II)

Coronary Artery Disease | Aortic Valve Disease

Denmark
Joshua Woolley, MD/PhD

Recruiting

Psilocybin Therapy for Chronic Low Back Pain (POP)

Chronic Low-back Pain

United States
Carmen Clapp
Universidad Autónoma de Querétaro; Instituto Mexicano de Oftalmologia (IMO); General... and other collaborators

Recruiting

Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

Mexico
The University of Texas Health Science Center,...
Cures Within Reach

Completed

Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease

Irritability | Huntington Disease

United States
Shanghai Institute Of Biological Products
First Affiliated Hospital Bengbu Medical College

Completed

A Study Exploring Efficacy of Pegloticase in Subjects With Asymptomatic Hyperuricemia

Asymptomatic Hyperuricemia

China
Institut National de la Santé Et de la Recherche...

Completed

Trial of Treatments for COVID-19 in Hospitalized Adults (DisCoVeRy)

Corona Virus Infection

Norway, Austria, France, Greece, Portugal, Belgium, Luxembourg
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); Eli Lilly and Company; Kanisa Pharmaceuticals

Completed

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Myelodysplastic Syndromes | Leukemia

United States, Israel
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

Malignant Neoplasm

United States, Guam
Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.

Healthy Subjects

France
McGill University Health Centre/Research Institute...

Terminated

Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain (PRO_GENE_POP)

Postoperative Pain

Canada
Fred Hutchinson Cancer Center

Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Primary Myelofibrosis | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

Malignant Neoplasm

United States
Ache Laboratorios Farmaceuticos S.A.

Suspended

Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu

Cold

Brazil
Brian J Lipworth

Completed

Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation

Allergic Rhinitis | Tachyphylaxis | Rhinitis Medicamentosa

United Kingdom
Merck Sharp & Dohme LLC

Completed

Study of MK-1029 in Participants With Persistent Asthma That Cannot Be Controlled With Montelukast (MK-1029-015)

Asthma
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects

Drug-induced Surface ECG Changes
Vanderbilt University Medical Center

Withdrawn

Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure NYHA Class I

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma

Asthma

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Withdrawn

Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma

Recurrent Mycosis Fungoides and Sezary Syndrome | Cutaneous T-Cell Non-Hodgkin Lymphoma | Stage IIB Mycosis Fungoides and Sezary Syndrome | Stage IIIA Mycosis Fungoides and Sezary Syndrome | Stage IIIB Mycosis Fungoides and Sezary Syndrome | Stage IVA Mycosis Fungoides and Sezary Syndrome | Stage...
Bayer

Completed

Study of Nifedipine GITS and Candesartan Combination Compared to Monotherapy in Patients With Essential Hypertension (DISTINCT)

Hypertension, Essential

Spain, Argentina, United States, Canada, Korea, Republic of, Italy, Russian Federation, South Africa, Ukraine, Belgium, Brazil, Lithuania, United Kingdom
National Cancer Institute (NCI)

Completed

Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia

Rectal Cancer | Colon Cancer | Precancerous Condition

United States
EMD Serono

Terminated

Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Germany
Masoud Saatchi

Completed

Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis

Local Anesthesia
Hoffmann-La Roche

Completed

A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate (SCORE)

Rheumatoid Arthritis

Germany, Spain, Switzerland, Canada, Estonia, Greece, France, Russian Federation, Netherlands, Turkey, Serbia, Argentina, Latvia, Lithuania, Denmark, Romania, Brazil, Czech Republic, Norway
Orexigen Therapeutics, Inc

Completed

A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects

Obesity | Overweight

United States
Pfizer

Completed

Study Evaluating The Effects Of Bazedoxifene/Conjugated Estrogens On Endometrial Safety And Postmenopausal Osteoporosis

Menopause | Osteoporosis

United States, Colombia, Australia, Hungary, Poland, Finland, Argentina, Chile, Denmark, Mexico, New Zealand, Norway
Bankole Johnson
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Combined Pharmacotherapies for Alcoholism

Alcoholism

United States
Singapore National Eye Centre
International Stem Cell Forum

Completed

Thyroid Treatment Trial

Graves Ophthalmopathy

Singapore
University of Maryland, Baltimore

Not yet recruiting

Effect of RECK in Posterior Spinal Fusion

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Lumbar Spinal Stenosis | Degenerative Disease

United States
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Recruiting

Bioequivalence With Clinical Endpoint Study of Fluticasone Propionate 100 mcg and Salmeterol 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 mcg Inhalation Powder/GSK in Patients With Asthma (AERO-PD)

Asthma

Greece
Marmara University

Recruiting

The Effect of Central Sensitization on Treatment Response in Patients With Fibromyalgia

Fibromyalgia | Central Sensitisation

Turkey
Organon and Co

Completed

Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate and Medium Dose Mometasone Furoate (Study P05122 AM1)(COMPLETED)

Asthma | Airway Inflammation
Sumitomo Pharma America, Inc.

Completed

A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia

Schizophrenia

United States
The University of Texas Health Science Center at...

Completed

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

Periodontal Diseases

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer (e3)

Breast Cancer

United States, Puerto Rico
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

Endometrial Clear Cell Adenocarcinoma | Endometrial Dedifferentiated Carcinoma | Endometrial Endometrioid Adenocarcinoma | Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Recurrent Endometrial Adenocarcinoma | Recurrent Endometrial... and other conditions

United States, Korea, Republic of, Canada, Puerto Rico, Japan
Pardes Biosciences, Inc.

Completed

Study of PBI-0451 in Healthy Subjects.

Covid19

New Zealand
Avanir Pharmaceuticals
Michael J. Fox Foundation for Parkinson's Research

Completed

Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Patients (LID in PD)

Parkinson's Disease | Dyskinesia

Canada, United States
Avanir Pharmaceuticals

Completed

Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis (PRIME)

Multiple Sclerosis | Central Neuropathic Pain

United States, Spain, Czechia, Poland, Argentina

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