Search clinical trials for: APG 5.0

Total 7124 results

Universitaire Ziekenhuizen KU Leuven

Completed

Suture Materials: an Evaluation

Suture Materials
AO GENERIUM

Recruiting

A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II

Metabolic Diseases | Mucopolysaccharidosis Type II

Russian Federation
aTyr Pharma, Inc.
Foundation for Sarcoidosis Research

Completed

Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis

Pulmonary Sarcoidosis

United States
BioMarin Pharmaceutical

Terminated

Phase IIb Study of PRO045 in Subjects With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Belgium, Netherlands, France, United Kingdom, Italy
Southwest Oncology Group
National Cancer Institute (NCI)

Recruiting

Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Lung Adenocarcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Squamous Non-Small Cell Carcinoma

United States, Guam
Duke University
Medartis AG

Completed

Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws

Post-traumatic Osteoarthritis, Unspecified Ankle and Foot | Localized, Primary Osteoarthritis of the Ankle and/or Foot

United States
Celtic Pharma Development Services

Completed

Xerecept Intravenous Dose Escalation in Japanese and Caucasian Volunteers

Edema

United States
Lyle Joyce
Abiomed Inc.

Recruiting

Impella Supported OPCABG

Ischemic Cardiomyopathy

United States
Coeus Health, LLC

Completed

Using an API to Commercialize an Evidence-Based Weight Loss Intervention

Weight Loss | Health Behavior

United States
Amgen

Completed

A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants

Healthy Participants

United States
Amgen

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-AMG 510 Following a Single Oral Dose in Healthy Male Subjects

Healthy Subjects

United States
Amgen

Withdrawn

AMG 745 in Subjects With Age-associated Muscle Loss

Age-associated Muscle Loss
University of Michigan Rogel Cancer Center
Rush University Medical Center

Completed

Dose-Escalation Study of Intensity-Modulated Radiotherapy(IMRT)in Patients With Unresectable Pancreatic Cancer

Pancreatic Cancer

United States
University of California, San Francisco

Withdrawn

Evaluating the Feasibility of Disseminating a Novel Mobile Platform to Treat Depression (PRIME-D)

Depression

United States
Micah Skeens
National Institute of Nursing Research (NINR)

Recruiting

BMT4me: Post-HSCT Medication Adherence mHealth App (Bmt4me 2)

Adherence, Medication | Stem Cell Transplant | Digital Health

United States
Journey Medical Corporation

Completed

A Dose-Ranging Study of the Effect of Glycopyrrolate in Subjects With Axillary Hyperhidrosis

Hyperhidrosis

United States
University of Alabama, Tuscaloosa

Unknown

ACAR Brain Health Intervention Study

Aging Well

United States
Betta Pharmaceuticals Co., Ltd.
Tigermed Consulting Co., Ltd

Completed

Icotinib Hydrochloride Cream in Patients With Mild to Moderate Psoriasis

Psoriasis

China
Georgetown University
Riverain Technologies

Completed

Testing of Computer Aided Detection Software for Riverain Medical Group

Lung Cancer

United States
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)

Dry Eye Disease

United States
Regado Biosciences, Inc.

Completed

Safety, Tolerability and PK/PD of RB006 in a Healthy Volunteer SAD (SC101)

Healthy Volunteer

United States
University of Sao Paulo
Grand Challenges Canada; Fundaçao Maria Cecilia Souto Vidigal

Completed

A Smartphone-Assisted Brief Behavioral Intervention for Pregnant Women With Depression

Perinatal Depression

Brazil
Amgen

Completed

Single Ascending Dose Study of AMG 570 in Healthy Subjects

Systemic Lupus Erythematosus

United States
Santen Inc.

Completed

A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration (PAVE)

Age-Related Macular Degeneration

United States
Tel-Aviv Sourasky Medical Center

Completed

Validation of Serenno CUO and IAP Measuring Device

Laparoscopic Surgery | Urinary Catheter

Israel
Revolution Medicines, Inc.
Sanofi; Amgen

Active, not recruiting

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Non-Small Cell Lung Cancer

United States, Korea, Republic of, Canada, Taiwan, Spain, United Kingdom, Italy, Australia, France, Germany
Bausch Health Americas, Inc.

Completed

(C2013-0302) Safety and Efficacy of Escalating Doses of SAN-300 in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Recruiting

APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors

Solid Tumor | Neuroblastoma

China
Ascentage Pharma Group Inc.

Recruiting

A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With T-PLL

T-Prolymphocytic Leukemia

United States
Mayo Clinic
Medtronic

Terminated

Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy

Parotid Gland Disorders

United States
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Recruiting

APG-2449 in Patients With Advanced Solid Tumors

Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Malignant Pleural Mesothelioma | Advanced Solid Cancer

China
University of Southampton

Not yet recruiting

Attentional Bias Modification Training for People With Chronic Musculoskeletal Pain (I-ABMT)

Chronic Pain

United Kingdom
Johns Hopkins University
SARcode Bioscience

Terminated

SAR 1118 in Human Subjects Undergoing Pars Plana Vitrectomy

Pars Plana Vitrectomy | Diabetic Macular Edema (DME)

United States
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Terminated

APG-1252 in Patients With SCLC or Advanced Solid Tumors

Small Cell Lung Cancer and Other Solid Tumors

China
Ascentage Pharma Group Inc.

Completed

A Study of APG-1252 in Patients With SCLC or Other Solid Tumors

Small Cell Lung Cancer | Solid Tumor

United States
Ahram Canadian University

Completed

Post-instrumentation Pain After Use of the Fanta and M3 Pro Gold Systems

Endodontic Treatment

Egypt
Cerevel Therapeutics, LLC

Recruiting

A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy

Apathy in Dementia

United States, Canada
Ablynx

Completed

Dose Ranging Study of ALX-0171 in Infants Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection (Respire)

Respiratory Syncytial Virus Lower Respiratory Tract Infection

Belgium, Hungary, Israel, Spain, Estonia, Philippines, Thailand, Bulgaria, Poland, Germany, Chile, Colombia, Croatia, Czechia, Latvia, Malaysia, Slovakia
Amgen

Completed

Multiple Ascending Doses of Rozibafusp Alfa (AMG 570) in Adults With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Germany
Asan Medical Center

Completed

The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients

Pulmonary Emphysema

Korea, Republic of
Edesa Biotech Inc.
JSS Medical Research Inc.

Active, not recruiting

Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis

Allergic Contact Dermatitis

United States, Canada
Duke University

Recruiting

Navigation Study: Durham

Prenatal; Postnatal

United States
Starpharma Pty Ltd

Completed

Dose Ranging Study of SPL7013 Gel for Treatment of Bacterial Vaginosis (BV)

Bacterial Vaginosis

United States
Janssen Pharmaceutical K.K.

Withdrawn

Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)

Macular Degeneration | Geographic Atrophy | Visual Acuity

Japan
VBI Vaccines Inc.
Clinical Trial Data Services, LLC

Completed

Study to Evaluate Safety, Tolerability, and Immunogenicity of Candidate Human Cytomegalovirus Vaccine in Healthy Adults

Cytomegalovirus Infections

Canada
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of GSK2292767 in Healthy Participants Who Smoke Cigarettes

Asthma

United Kingdom
Novo Nordisk A/S

Completed

A Research Study to Investigate How Well NNC0165-1875 in Combination With Semaglutide Works in People With Obesity

Obesity

United States
Aveta Biomics, Inc.

Recruiting

Safety and Efficacy of APG-157 in Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of Oral Cavity

United States
Ascentage Pharma Group Inc.

Completed

APG-115 in Patients With Advanced Solid Tumors or Lymphomas (APG-115)

Patients With Advanced Solid Tumor or Lymphoma

United States
Ascentage Pharma Group Inc.

Recruiting

APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies

Hematologic Malignancies

United States, Australia

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