Search clinical trials for: APX-115

Total 4801 results

OncoVerity, Inc.
Janssen Research & Development, LLC; argenx

Completed

A Study of ARGX-110 in Participants With Advanced Malignancies

Neoplasms

France, Belgium
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Cannabinoid CB1 Receptors Using [11C]MePPEP

Healthy

United States
Taiho Oncology, Inc.

Terminated

An Investigation of TAS-119 Monotherapy

Advanced Solid Tumors

Italy, Spain, United States, Netherlands, United Kingdom
Taiho Oncology, Inc.

Completed

A Study of TAS-116 in Patients With Solid Tumors

Advanced Solid Tumors

United States, United Kingdom, Italy
Placon Therapeutics

Unknown

A Study to Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA Mutations

Breast Neoplasms | Prostatic Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States
M.D. Anderson Cancer Center
Direct Therapeutics

Completed

Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas

Glioma | Brain Neoplasms

United States
Oriental Neurosurgery Evidence-Based-Study Team

Unknown

11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes

Parkinson Disease

China
Takeda

Completed

Phase 1 TAK-915 Single-Dose Positron Emission Tomography (PET) Occupancy Study

Healthy Volunteers

United States
Auris Medical AG

Completed

AM-111 in the Treatment of Acute Inner Ear Hearing Loss (HEALOS)

Hearing Loss

Bulgaria
Gitte Moos Knudsen

Completed

[11C]Cimbi-36 Dosimetry

Healthy

Denmark
Mallinckrodt

Terminated

Study to Evaluate the Effect of Age (Geriatric) and Kidney Function on the Safety, Efficacy and Pharmacokinetics of OctreoScan in Patients Who Have New or Recurrent Tumors

Solid Tumors

United States
Walter Reed Army Institute of Research (WRAIR)
National Institute of Mental Health (NIMH); National Intrepid Center of Excellence

Recruiting

CNS Correlates of Extended Sleep Restriction

Sleep Restriction

United States
NovaRock Biotherapeutics, Ltd

Not yet recruiting

Evaluation of the Safety and Efficacy of NBL-015 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
4D Molecular Therapeutics

Active, not recruiting

Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia

Choroideremia

United States
ORIC Pharmaceuticals

Completed

Effect of Food on the Pharmacokinetics of ORIC-114

Food Effect in Healthy Participants

Australia
University of Pennsylvania

Terminated

11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation

Mild Cognitive Impairment

United States
REGENXBIO Inc.

Active, not recruiting

RGX-111 Gene Therapy in Patients With MPS I

Hurler Syndrome | Hurler-Scheie Syndrome | Mucopolysaccharidosis Type I (MPS I)

United States, Brazil, Israel
Dongkook Pharmaceutical Co., Ltd.

Active, not recruiting

Efficacy and Safety of DKB-119 in Patients in Crow's Feet

Crow's Feet

Korea, Republic of
Promontory Therapeutics Inc.

Completed

A Phase 1/2a Dose-Finding Study of PT-112 in Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States
University of Pennsylvania
University of Miami; Biogen; University of Kansas

Terminated

Multimodal Imaging Outcome Measures for ALS (Image ALS)

ALS

United States
Yonsei University

Completed

K-BASKET, TAS-117, PI3K/AKT Gene Aberration

Solid Tumor, Adult

Korea, Republic of
SecuraBio

Completed

Duvelisib in Hepatically Impaired Subjects Compared to Healthy Subjects (IPI-145-14)

Hepatic Impairment

United States
argenx

Completed

A Study to Compare the PK, PD and Safety and Tolerability of a SC With an IV Formulation of ARGX-113 in Healthy Male Subjects

Bioavailability Study

Netherlands
Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
Jazz Pharmaceuticals

Completed

"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" (OSA)

Obstructive Sleep Apnea

United States, Finland, Germany, France, Sweden
University of Illinois at Chicago
Rush University Medical Center; American Society for Parenteral and Enteral...

Completed

Feeding the Critically Ill During Phases of Altered Redox Status (FEDOX)

Systemic Inflammatory Response Syndrome | Oxidative Stress | Acute Respiratory Distress Syndrome | Euthyroid Sick Syndromes

United States
Johns Hopkins University
National Institute on Aging (NIA)

Completed

PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers

Alzheimer's Disease

United States
Draeger Medical Systems, Inc.

Completed

Efficacy Study of the Draeger Jaundice Meter (JM-105) in Neonates of ≥ 24 Weeks of Gestational Age

Hyperbilirubinemia | Neonatal Jaundice

Canada
Synektik S.A.
European Commission

Completed

A Phase I Study of a Novel Tracer for Positron Emission Tomography "PET" Myocardial Perfusion Imaging "MPI"

Coronary Artery Disease
Kissei Pharmaceutical Co., Ltd.

Completed

Phase II Exploratory Clinical Study of KUX-1151

Hyperuricemia

Japan
BioMarin Pharmaceutical

Approved for marketing

BMN 110 US Expanded Access Program

Morquio A Syndrome | MPS IVA | Mucopolysaccharidosis IVA

United States, Puerto Rico
Takeda

Completed

Safety and Tolerability Study of TAK-165 in Subjects With Tumors Expressing HER2

Breast Neoplasm | Ovarian Neoplasm | Pancreatic Neoplasm | Lung Neoplasm | Renal Neoplasm

United States
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
Wyeth is now a wholly owned subsidiary of Pfizer
Emergent Product Development Seattle LLC

Terminated

Study of TRU-015 in Subjects With Membranous Nephropathy Secondary to Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of SAM-315 in Healthy Adults

Alzheimer Disease
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
Noema Pharma AG

Completed

A 10-week Efficacy Study of NOE-105 in Childhood Onset Fluency Disorder (Orpheus)

Childhood-Onset Fluency Disorder

United States, Australia
Centre Hospitalier St Anne
Roche Pharma AG

Recruiting

Impact of Microglial Activation on Synaptic Density in Alzheimer's Disease (GliSyn)

Alzheimer Disease

France
Guangzhou University of Traditional Chinese Medicine

Unknown

Study on Vulnerable Plaque of Carotid Artery With Chinese Herbal and Insects Medicine (Spchim)

Carotid Artery Plaque
Guangzhou University of Traditional Chinese Medicine
Liaoning Tumor Hospital & Institute; Zhongshan People's Hospital, Guangdong... and other collaborators

Unknown

Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117 (PRISIT)

Occlusion and Stenosis of Unspecified Cerebral Artery
Vanderbilt University Medical Center

Active, not recruiting

Quantitative Imaging of Brain Glymphatic Function in Humans

Parkinson Disease

United States
argenx

Not yet recruiting

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS) (ReALiSe)

Amyotrophic Lateral Sclerosis
argenx

Recruiting

ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function (VARVARA)

Delayed Graft Function

Australia, Spain, Belgium, France, Portugal, Canada
argenx

Recruiting

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy (ARDA+)

Multifocal Motor Neuropathy (MMN)

United Kingdom, Spain, United States, Italy, Netherlands, Germany, France, Belgium, Canada, Poland, Austria
argenx

Active, not recruiting

A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy (ARDA)

Multifocal Motor Neuropathy

United States, France, Germany, Belgium, Italy, Netherlands, Canada, United Kingdom, Austria, Poland, Spain
BioAge Labs, Inc.

Terminated

Study to Evaluate the Safety, Tolerability, and Efficacy of BGE-175 in Hospitalized Adults With Coronavirus Disease 2019 (COVID-19) That Are Not in Respiratory Failure

Covid19

United States, Brazil, Argentina
University of Aarhus

Completed

Validation of 3-[11C]-OHB

Heart Failure | Healthy | Diabetes Mellitus, Type 2

Denmark
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi

Completed

Translation and Validation of the Turkish Version of the ObsQoR-11 Questionnaire (ObsQoR-11T)

Cesarean Section | General Anesthesia | Patient Reported Outcome Measures | Quality of Recovery

Turkey
H. Lundbeck A/S

Completed

A Brain Imaging PET Study of [11C]-Lu AF88370 in Healthy Adult Male Participants

Healthy Participants

United Kingdom

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