Search clinical trials for: AVP-21D9

Total 4853 results

Emergent BioSolutions
National Institutes of Health (NIH)

Completed

Safety and Pharmacokinetics Study of Human Monoclonal Antibody (AVP-21D9)

Anthrax

United States
Columbia University
National Institute on Aging (NIA)

Completed

Comparison of AVF Versus AVG in Elderly Patients Starting Dialysis

Chronic Kidney Disease | Endstage Renal Disease

United States
Johns Hopkins University

Recruiting

Microvascular Plug (MVP) for the Treatment of Pulmonary ArterioVenous Malformations (PAVMs)

Pulmonary Arteriovenous Malformation

United States
MBX Biosciences

Completed

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects

Healthy

United States
Innolake Biopharm

Not yet recruiting

A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies

Melanoma | Soft Tissue Sarcoma | Cervical Cancer | Head and Neck Cancer | Nasopharyngeal Carcinoma | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Classic Hodgkin Lymphoma
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Phase I Clinical Study of HRS-2189 in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Kissei Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia and Pain

Uterine Fibroids (MeSH Heading: Leiomyoma)

Japan
Mario Negri Institute for Pharmacological Research

Recruiting

Acoustic Analysis of VA Sounds (VAsound)

End Stage Renal Disease | Hemodialysis Access Failure

Italy
Biomea Fusion Inc.

Recruiting

Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus (BF-MNN-112)

Type 1 Diabetes Mellitus

United States, Canada
Kissei Pharmaceutical Co., Ltd.

Completed

A Phase II Randomized Open Label Study of KLH-2109 in Patients With Endometriosis

Endometriosis

Japan
University of Pittsburgh

Terminated

Trial of Fistula Versus Graft in Elderly Patients

End Stage Renal Disease | Arteriovenous Fistula | Arteriovenous Graft

United States
Biomea Fusion Inc.

Recruiting

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

Colorectal Cancer | Pancreatic Cancer | NSCLC | Non Small Cell Lung Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | CRC | KRAS Mutation-Related Tumors | Relapsed Cancer | Refractory Cancer | Stage IV Non-small Cell Lung Cancer | Stage IV Colorectal Cancer | Stage III Non-small Cell Lung Cancer | Stage III NSCLC and other conditions

United States, Korea, Republic of
Kissei Pharmaceutical Co., Ltd.

Completed

A Randomized Open Label Study of KLH-2109 in Patients With Endometriosis(1)

Endometriosis

Japan
LeMaitre Vascular

Active, not recruiting

LeMaitre LifeSpan® ePTFE Vascular Graft Retrospective Registry

Diseased or Occluded Blood Vessels | Arteriovenous Shunting for Blood Access

Germany
Rapport Therapeutics Inc.

Not yet recruiting

Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal Epilepsy

Focal Onset Seizures
The Hong Kong Polytechnic University
Tuen Mun Hospital

Recruiting

Program Using a Mobile Application Versus Telephone Advice on Patients at Risk of Coronary Heart Disease : a Pilot RCT

Coronary Heart Disease

Hong Kong
Kissei Pharmaceutical Co., Ltd.

Completed

A Randomized, Placebo-controlled, Double-blind Study of KLH-2109 in Patients With Endometriosis (2)

Endometriosis

Japan
Afferent Pharmaceuticals, Inc.

Completed

A Four-Week Multicenter Study Evaluating the Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Subjects With Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Biomea Fusion Inc.

Recruiting

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Lymphoma | Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Cancer | Progression | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Plasma Cell Myeloma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Refractory | Myeloma, Plasma-Cell | Myelomatosis | Acute Mixed-Phenotype...

United States, Spain, Netherlands, Greece, Italy
Afferent Pharmaceuticals, Inc.

Completed

A Study to Assess the Tolerability of a Single Dose of Gefapixant (AF-219/MK-7264) in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States
Afferent Pharmaceuticals, Inc.

Completed

Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)

Refractory Chronic Cough

United Kingdom
Afferent Pharmaceuticals, Inc.

Completed

A Study to Assess the Efficacy of Gefapixant (MK-7264/AF-219), in Participants With Chronic Cough (MK-7264-006) (EPICC)

Chronic Cough
Afferent Pharmaceuticals, Inc.

Completed

A Study of Gefapixant (AF-219/MK-7264) in Participants With Idiopathic Pulmonary Fibrosis (IPF) With Persistent Cough (MK-7264-016)

Cough | Idiopathic Pulmonary Fibrosis
Avanir Pharmaceuticals

Completed

Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis Patients

Multiple Sclerosis

United States
Avanir Pharmaceuticals

Completed

Pharmacokinetics (PK) and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia
Medtronic Cardiac Rhythm and Heart Failure

Completed

SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction (SAVEPACe)

Atrial Fibrillation | Bradycardia | Ventricular Dysfunction | Heart Failure, Congestive | Sick Sinus Syndrome

United States, Canada
Biomea Fusion Inc.

Recruiting

Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)

Type 2 Diabetes Mellitus

United States, Canada
Afferent Pharmaceuticals, Inc.

Completed

A Dose Escalation Study of Gefapixant (AF-219/MK-7264) in Refractory Chronic Cough (MK-7264-010)

Refractory Chronic Cough
Afferent Pharmaceuticals, Inc.

Completed

An 8-Week Refractory Chronic Cough Study (MK-7264-021)

Refractory Chronic Cough

United States
Afferent Pharmaceuticals, Inc.

Completed

Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014)

Refractory Chronic Cough
Otsuka Pharmaceutical Development & Commercialization...

Completed

Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Participants With Dementia of the Alzheimer's Type

Agitation in Participants With Dementia of the Alzheimer's Type

United States, Canada
Shanghai Changzheng Hospital
First Affiliated Hospital of Zhejiang University; The First Affiliated Hospital... and other collaborators

Unknown

Vascular Access Choice and Outcomes in the Elderly and Very Elderly With End Stage Renal Disease in China (ACCESS-China)

End Stage Renal Disease

China
Imperial College London
Duska Scientific Co.

Completed

ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)

Smoking | Asthma | COPD

United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Completed

Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Participants With Traumatic Brain Injury

Neurobehavioral Disinhibition

United States
Replicor Inc.

Completed

REP 2139-Ca / Pegasys™ Combination Therapy in Hepatitis B / Hepatitis D Co-infection

Chronic HBV Infection (HBeAg Negative)

Moldova, Republic of
Hoffmann-La Roche

Completed

A Phase 1, Randomized, Double-blind, Placebo-controlled Crossover Study of RG7314 on the Potential Regulation of Higher Brain Functions in Healthy Male Participants: Proof of Mechanism

Healthy Volunteer

Netherlands
Avanir Pharmaceuticals

Completed

A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia
Kadmon Corporation, LLC

Completed

Phase 2, Open-label, Study of KD025 in Subjects With Psoriasis Vulgaris Who Failed First-line Therapy

Psoriasis Vulgaris

United States
Afferent Pharmaceuticals, Inc.

Terminated

The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)

Bladder Pain Syndrome

United States
Kadmon, a Sanofi Company

Completed

A Study to Determine the Effect of Multiple Oral Doses of SLx-2119 in Healthy Male Subjects

Immune System Disorder (Healthy Volunteer)

United States
Kadmon Corporation, LLC

Completed

A Safety and Tolerability Study of Belumosudil (KD025) Treatment in Subjects With Moderately Severe Psoriasis Vulgaris

Psoriasis Vulgaris

United States
NVP Healthcare

Recruiting

To Evaluate the Safety and Efficacy of NVP-2203 Tablet in Patients

Cardiovascular Diseases

Korea, Republic of
Avanir Pharmaceuticals

Completed

Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)

Stroke | Parkinson's Disease | Traumatic Brain Injury | Alzheimer's Disease

United States
NVP Healthcare

Completed

Pharmacokinetic Interaction and Safety Between NVP-1203-R1 and NVP-1203-R2 (Navipharm)

Healthy

Korea, Republic of
NVP Healthcare

Completed

Pharmacokinetic Interaction and Safety/Tolerability Between NVP-1805-R1 and NVP-1805-R2

Healthy

Korea, Republic of
NVP Healthcare

Withdrawn

Pharmacokinetic Interaction and Safety/Tolerability Between NVP-1603-1 and NVP-1603-2

Healthy
University of Victoria

Recruiting

Physical Activity Promotion in Children Using a Novel Smartphone Game: A Pilot Randomized Controlled Trial

Physical Activity

Canada
Hypnalgesics, LLC
Tufts University

Completed

Nonpharmacologic Reduction of Periprocedural Distress and Drug Use

Dental Anxiety | Opioid Use | Drug Use | Dental Pain

United States
NVP Healthcare

Completed

Efficacy and Safety of NVP-1203 and NVP-1203-R in Patients With Acute Low Back Pain

Acute Low Back Pain

Korea, Republic of
NVP Healthcare

Completed

Efficacy and Safety of NVP-1203 in Patients With Acute Low Back Pain

Acute Low Back Pain

Korea, Republic of

Search clinical trials for: AVP-21D9

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