Search clinical trials for: Ad-RTS-hIL-12 and Veledimex

Total 252 results

Alaunos Therapeutics

Completed

Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102

Glioblastoma

United States
Alaunos Therapeutics

Completed

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer

Metastatic Breast Cancer

United States
Alaunos Therapeutics

Completed

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma

United States
Alaunos Therapeutics

Terminated

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor

United States
Alaunos Therapeutics

Completed

Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma

Glioblastoma

United States
Alaunos Therapeutics

Completed

A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102

Glioblastoma

United States
Alaunos Therapeutics

Completed

Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma

Melanoma

United States
Alaunos Therapeutics

Completed

Adenoviral Vector Monotherapy or Combination With Chemotherapy in Subjects With Recurrent/Metastatic Breast Cancer.

Breast Cancer Nos Metastatic Recurrent

United States
Wageningen University

Completed

Sustained Effect of Food Texture of Ultra-processed Foods on Energy Intake

Eating Behavior

Netherlands
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to an Investigational HIV-1 Vaccine With or Without Interleukin-12 (IL-12) in HIV-1 Infected Adults

HIV Infections

United States
OncoSec Medical Incorporated

Terminated

Phase II Intratumoral IL12 Plasmid Electroporation in Cutaneous Lymphoma (CTCL)

Mycosis Fungoides (MF) | Cutaneous T Cell Lymphomas (CTCL)

United States
OncoSec Medical Incorporated
National Cancer Institute (NCI)

Completed

IL-12 Gene and in Vivo Electroporation-Mediated Plasmid DNA Vaccine Therapy in Patients With Merkel Cell Cancer (MCC)

Merkel Cell Carcinoma

United States
OncoSec Medical Incorporated

Terminated

Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC)

Head and Neck Squamous Cell Carcinoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to an HIV Preventive Vaccine (HIV-1 Gag DNA Alone or With IL-15 DNA) Given With or Without 2 Different Booster Vaccinations in HIV Uninfected Adults

HIV Infections

United States, Brazil
Nantes University Hospital

Terminated

A Study of Immunotherapy With TIL (Tumor Infiltrating Lymphocytes) in Combination With Intra-tumoral Injections of Interferon Gamma-adenovirus (Ad-IFNg) in Patients With Stage IIIc or Stage IV Metastatic Melanoma (AJCC)(Protocol TIL-Ad-INFg)

Metastatic Melanoma

France
OncoSec Medical Incorporated

Completed

Trial of pIL-12 Electroporation Malignant Melanoma (IL-12MEL)

Melanoma

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Melanoma

Melanoma (Skin)

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Vaccine Therapy Plus Interleukin-12 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

Prostate Cancer

United States
GlaxoSmithKline

Completed

Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants

Malaria | Malaria Vaccines

Tanzania
H. Lee Moffitt Cancer Center and Research Institute
National Gene Vector Laboratory

Completed

Phase I Trial of Intratumoral pIL-12 Electroporation in Malignant Melanoma

Malignant Melanoma

United States
Antisoma Research

Completed

Study of AS1409 in Patients With Either Metastatic Renal Cell Carcinoma or Metastatic Malignant Melanoma

Metastatic Renal Cell Carcinoma | Metastatic Malignant Melanoma

United Kingdom, New Zealand
International AIDS Vaccine Initiative
Auro Vaccines LLC; Ichor Medical Systems Incorporated

Completed

Safety and Immunogenicity Study of HIV-MAG Vaccine +/- IL-12 and Ad35-GRIN/ENV in HIV-uninfected Volunteers

HIV Infections

Rwanda, Uganda, Kenya
National Institute of Allergy and Infectious Diseases...
Auro Vaccines LLC

Completed

Therapeutic Vaccine for HIV

HIV | Therapeutic Vaccine

United States
Neumedicines Inc.
Department of Health and Human Services

Completed

Safety and Tolerability of HemaMax™ (rHuIL-12) as Radiation Countermeasure

Hematopoietic Syndrome Due to Acute Radiation Syndrome

United States
Neumedicines Inc.
Department of Health and Human Services

Completed

Safety Study of HemaMax™ (rHuIL-12) to Treat Acute Radiation Syndrome

Hematopoietic Syndrome Due to Acute Radiation Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults

HIV Infections

United States
University Health Network, Toronto
Ozmosis Research Inc.

Recruiting

A Study of (Interleukin-12) IL-12 in Patients With Acute Myelogenous Leukemia (AML)

Acute Myeloid Leukemia

Canada
EGEN, Inc.

Completed

Safety and Efficacy of EGEN-001 Combined With Carboplatin and Docetaxel in Recurrent, Platinum-Sensitive, Ovarian Cancer

Ovarian Neoplasms

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Cancer in the Abdomen

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Anal Cancer | Gallbladder Cancer

United States
Beth Israel Deaconess Medical Center
Harvard Medical School (HMS and HSDM); National Cancer Institute (NCI); Dana-Farber... and other collaborators

Terminated

Vaccination of Patients With Breast Cancer With Dendritic Cell/Tumor Fusions and IL-12

Breast Cancer

United States
Baylor College of Medicine

Completed

Vector Delivery of the IL-12 Gene in Men With Prostate Cancer

Prostatic Neoplasms | Prostate Cancer

United States
Merck Sharp & Dohme LLC
HIV Vaccine Trials Network

Terminated

Investigation of V520 in an HIV Vaccine Proof-of-Concept Study (V520-023)

HIV Infections | AIDS
National Cancer Institute (NCI)

Completed

NHS-IL12 for Solid Tumors

Epithelial Tumors, Malignant | Epithelial Neoplasms, Malignant | Malignant Mesenchymal Tumor

United States
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety and Effectiveness of PENNVAX-B Vaccine Alone, With Il-12, or IL-15 in Healthy Adults

HIV Infections

United States
University of California, San Francisco
Merck Sharp & Dohme LLC; OncoSec Medical Incorporated

Completed

Trial of pIL-12/MK-3475 in Metastatic Melanoma

Melanoma

United States
National Cancer Institute (NCI)

Terminated

Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer

Sarcoma | Breast Neoplasm | Lung Neoplasm | Kidney Neoplasm

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

EGEN-001 and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Ovarian Undifferentiated Carcinoma

United States
Chase Heaton, MD
Incyte Corporation; OncoSec Medical Incorporated

Terminated

Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Interleukin 12 (IL-12) for the Treatment of Cryptosporidiosis in AIDS Patients

HIV Infections | Cryptosporidiosis
National Institute of Allergy and Infectious Diseases...

Completed

Study of an HIV Preventive Vaccine Given With or Without an Adjuvant in HIV Uninfected Adults

HIV Infections

United States, Thailand
Providence Health & Services
OncoSec Medical Incorporated

Completed

CORVax12: SARS-CoV-2 Spike (S) Protein Plasmid DNA Vaccine Trial for COVID-19 (SARS-CoV-2) (CORVax12)

SARS-CoV-2

United States
Walter Sisulu University
Medical University of Graz; Nelson Mandela Academic Hospital; Umtata General...

Not yet recruiting

Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero (ARTMOMSBABES)

In Utero Drug Exposure

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to the PENNVAX-B DNA Vaccine With and Without IL-12 in HIV-uninfected Adults

HIV Infections

United States
Addpharma Inc.

Completed

Evaluating the Pharmacokinetic Characteristics of AD-101 in Healthy Volunteers

Osteoporosis

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

ABOD2011 in Patients With Advanced Solid Tumors Progressed After Standard Systemic Therapy

Patients With Advanced Solid Tumors

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Unresectable, Recurrent, or Refractory Head and Neck Cancer

Head and Neck Cancer

United States
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer

United States
OncoSec Medical Incorporated

Completed

Evaluation of Pharmacodynamic Effects of IT-pIL12-EP in Patients With TNBC (TNBC)

ER-Negative PR-Negative HER2-Negative Breast Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Terminated

Interleukin-12 and Interleukin-2 in Treating Patients With Refractory or Recurrent Neuroblastoma

Recurrent Neuroblastoma

United States

Search clinical trials for: Ad-RTS-hIL-12 and Veledimex

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Suriname

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations