Search clinical trials for: Adrenergic alpha-1 Receptor Agonists

Total 11030 results

American University of Beirut Medical Center

Completed

Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis

Myasthenia Gravis | Ocular Myasthenia Gravis

Lebanon
Shire

Completed

SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)

Phobia, Social | Anxiety, Separation | Generalized Anxiety Disorder (GAD)

United States
National Institute of Diabetes and Digestive and...

Withdrawn

Methyldopa for Reduction of DQ8 Antigen Presentation in At-Risk Subjects for Type 1 Diabetes (TN-23)

Type1 Diabetes Mellitus
New York State Psychiatric Institute
Shire

Completed

Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder

Oppositional Defiant Disorder | Attention Deficit Disorder | Childhood Aggression | Intermittent Explosive Disorder

United States
Lori A. Schweickert, MD
Shire

Completed

Inuniv and Working Memory

Attention Deficit Hyperactivity Disorder

United States
Alcon Research

Completed

A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Hermann Eye Center
Alcon Research

Completed

Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan

Ocular Hypertension | Open Angle Glaucoma | Pseudoexfoliation Syndrome

United States
UConn Health
Yale University; Shire

Withdrawn

Guanfacine Extended Release and Mindfulness Skills Therapy

Stress Disorder

United States
Uptown Eye Specialists

Completed

Brimonidine for Subconjunctival Hemorrhage From Femtosecond Laser Assisted Cataract Surgery

Cataract Surgery | Subconjunctival Hemorrhage

Canada
Allergan

Terminated

A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degeneration (BEACON)

Macular Degeneration | Geographic Atrophy

United States, Italy, United Kingdom, Germany, Australia, France
Isfahan University of Medical Sciences

Completed

Effect of Methyldopa on Uterine Artery Diameter in Pregnant Women With Mild Preeclampsia

Pregnant Women With Mild Preeclampsia
Research Foundation for Mental Hygiene, Inc.
Icahn School of Medicine at Mount Sinai; Bronx VA Medical Center

Unknown

Guanfacine Adjunctive Treatment to Atypical Antipsychotics for Cognitive Dysfunction in Schizophrenia (Guanfacine)

Schizophrenia | Schizoaffective Disorder | Cognitive Impairment

United States
Walter Reed Army Medical Center

Unknown

Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty

Ocular Hypertension | Glaucoma

United States
Szeged University
Department of Oral and Maxillofacial Surgery, University of Szeged; Institute...

Completed

Effects of Intraoperative, Goal-directed Crystalloid vs. Colloid Fluid Resuscitation on Free Flaps

Optimal Tissue Perfusion

Hungary
University Hospital, Grenoble

Unknown

Impact of Cardiac Blood Flow on Cerebral Blood Flow in Patients With Severe Traumatic Brain Injury (DEBITC)

Severe Traumatic Brain Injury With High Cerebral Pressure

France
University of Manitoba

Recruiting

Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury

Blood Loss, Surgical

Canada
Seoul National University Hospital

Completed

Effects of Vasopressor on the Graft Blood Flow in TRAM

Blood Flow | Flap Necrosis | Flap Ischemia | Anastomotic Failure of Flap

Korea, Republic of
IWK Health Centre

Terminated

Up-Down Determination of the ED90 of Phenylephrine for Hypotension Prophylaxis in Cesarean Delivery

Spinal Induced Hypotension in Cesarean Delivery
Eye Therapies, LLC
ORA, Inc.

Completed

A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)

Allergic Conjunctivitis

United States
Kasr El Aini Hospital

Unknown

Impact of Mirabegron on Erectile Function in BPH Patients

Males With Benign Prostatic Hyperplasia Symptoms
Federal University of Paraíba

Completed

Management of Hypertension in the Early Postpartum: a Randomized Controlled Trial

Hypertension | Pregnancy-Induced Hypertension in Postpartum | Postpartum Pre-Eclampsia

Brazil
Yale University
National Institute of Mental Health (NIMH); Massachusetts General Hospital; University... and other collaborators

Completed

Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder

Pervasive Development Disorders

United States
Icahn School of Medicine at Mount Sinai

Completed

Neurobiological Basis of Response to Guanfacine Extended Release in Children and Adolescents With ADHD

ADHD | Attention Deficit Hyperactivity Disorder

United States
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment

Adverse Effect
Tanta University

Not yet recruiting

Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy

Dexmedetomidine | Splenectomy | External Oblique Intercostal Plane Block

Egypt
Tehran Heart Center
Mahidol University; Shahid Beheshti University of Medical Sciences; Isfahan University... and other collaborators

Recruiting

Midodrine and Fludrocortisone for Vasovagal Syncope (COMFORTS)

Syncope, Vasovagal

Iran, Islamic Republic of
Richard Cartabuke

Completed

Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption

Adenoidectomy | Turbinate Surgery | Functional Endoscopic Sinus Surgery (FESS)

United States
Instituto Materno Infantil Prof. Fernando Figueira

Withdrawn

Maternal and Neonatal Outcomes of the Use of Vasopressors to Treat Hypotension During Spinal Anesthesia for Cesarean (Vasopressors)

Preeclampsia | Pregnancy Toxemias

Brazil
IWK Health Centre

Completed

Phenylephrine for Spinal Induced Hypotension

Hypotension

Canada
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
Boehringer Ingelheim

Completed

Telmisartan Compared With Enalapril in Elderly Patients With Blood Hypertension

Hypertension
The George Institute for Global Health, China
Shanghai East Hospital, China; First Affiliated Hospital of Chengdu Medical... and other collaborators

Completed

Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial (INTERACT4)

Cerebrovascular Disorders | Stroke, Acute

China
The University of Texas Medical Branch, Galveston

Completed

Esmolol vs. Labetalol in Endoscopic Sinus Surgery

Chronic Sinusitis

United States
Allergan

Completed

24-hour IOP-lowering Effect of Brimonidine 0.1%

Ocular Hypertension | Open-angle Glaucoma

United States
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States
The Cleveland Clinic
Murdoch University

Terminated

Mechanism and Treatment of Sympathetically Maintained Pain

Complex Regional Pain Syndrome (CRPS)

United States
Deventer Ziekenhuis

Completed

Pharmacokinetics and Clinical Effects of Escalating Doses of Clonidine in ICU Patients (Clokin1)

Delirium | Critical Illness

Netherlands
Richard Cartabuke

Withdrawn

Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption

Dental Anesthesia | Nasal Surgical Procedures | Intranasal Drug Administration

United States
Hospices Civils de Lyon

Completed

[11C]Yohimbine PET Study of alpha2-AR ([11C]Yohimbine)

Healthy Controls

France
Brian J Lipworth

Completed

Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation

Allergic Rhinitis | Tachyphylaxis | Rhinitis Medicamentosa

United Kingdom
University Hospital Schleswig-Holstein

Withdrawn

Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation (NIRSMED)

Cerebral Ischemia

Germany
General Hospital of Ningxia Medical University

Recruiting

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension

Outcome

China
Forest Laboratories

Completed

Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension

Stage 2 Hypertension | Stage 1 Hypertension

United States
Nova Scotia Health Authority

Completed

Ureteral Stent-related Pain and Mirabegron (SPAM) Trial (SPAM)

Nephrolithiasis

Canada
General Hospital of Ningxia Medical University

Recruiting

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension in Preeclamptic Patients

Adverse Effect

China
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

Alcohol Use

United States
Ocugen

Terminated

Study of Brimonidine Tartrate Nanoemulsion Eye Drops in Patients With Ocular Graft-vs-Host Disease (oGVHD)

Graft vs Host Disease | Ocular Surface Disease | Graft Versus Host Disease | Ocular Graft vs Host Disease | Ophthalmic Solutions | oGVHD | Brimonidine Tartrate | Lubricant Eye Drops

United States
University Hospital, Basel, Switzerland

Completed

Effect of Alphagan and Xalatan Eye Drops on Corneal Temperature

Primary Vascular Dysregulation

Switzerland
Federal University of São Paulo

Terminated

INFLUENCE OF TOPICAL INDOMETHACIN ON HYPOTHENSIVE EFFECT OF BRIMONIDINE

Glaucoma
University of Jordan

Completed

Caudal Bupivacaine vs Bupivacaine Plus Two Doses of Dexmedetomidine for Postoperative Analgesia in Children

Pain, Postoperative

Search clinical trials for: Adrenergic alpha-1 Receptor Agonists

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