Search clinical trials for: Alirocumab (Lyophilized formulation)

Total 1349 results

Sanofi
Regeneron Pharmaceuticals

Completed

Ascending Dose Study of the Safety and Tolerability of Alirocumab (SAR236553/REGN727) in Japanese Healthy Volunteers

Hypercholesterolemia

Japan
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Clinical Study of IBI362 in Healthy Chinese Male Subjects

Overweight/Obesity

China
Takeda

Completed

Safety and Immunogenicity of Three Formulations of Takeda's Tetravalent Dengue Vaccine Candidate (TDV)

Dengue Fever

United States
GlaxoSmithKline

Completed

To Assess Immunogenicity, Reactogenicity & Safety of 2 Formulations of GSK's HRV Vaccine as 2-dose Vaccination (Infants)

Infections, Rotavirus

Panama
Janssen Research & Development, LLC

Completed

A Study to Assess the Pharmacokinetic Comparability of Guselkumab (CNTO1959) When Delivered by 2 Different Devices and as 2 Formulations in Healthy Participants

Healthy

United States
Themis Bioscience GmbH

Completed

Safety, Tolerability and Long-term Immunogenicity of Different Formulations of a Chikungunya Vaccine (V184-005)

Chikungunya Virus Infection

United Kingdom
University of Alberta
University of British Columbia; McGill University; University of Calgary

Active, not recruiting

Multicentre Blinded Comparison of Lyophilized Sterile Fecal Filtrate to Lyophilized Fecal Microbiota Transplant in Recurrent Clostridioides Difficile Infection

Clostridium Difficile Diarrhea | Clostridia Difficile Colitis

Canada
Butantan Institute
Fundação de Amparo à Pesquisa do Estado de São Paulo; Banco Nacional de Desenvolvimento... and other collaborators

Unknown

Phase II Trial to Evaluate Safety and Immunogenicity of a Dengue 1,2,3,4 (Attenuated) Vaccine

Dengue

Brazil
GlaxoSmithKline

Completed

Safety Study of 2 Formulations of GSK's Human Rotavirus (HRV) Vaccine (444563), in Healthy Infants Starting at Age 6-12 Weeks

Infections, Rotavirus

United States, Taiwan, Canada, Hong Kong, Turkey
Fundación Hipercolesterolemia Familiar

Completed

Alirocumab and Plaque Burden In Familial Hypercholesterolaemia (ARCHITECT)

Familial Hypercholesterolemia

Spain
Centers for Disease Control and Prevention
Bavarian Nordic; Kinshasa School of Public Health; Ministry of Public Health,...

Active, not recruiting

JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo

Monkeypox Virus Infection

Congo, The Democratic Republic of the
Westside Medical Associates of Los Angeles
Regeneron Pharmaceuticals; University of Washington

Unknown

Assessment of Atherosclerotic Plaque Characteristics Change by DCE-MRI With Alirocumab

Atherosclerosis | Hyperlipidemia

United States
Population Health Research Institute

Completed

Effects of Acute, Rapid Lowering of LDL Cholesterol With Alirocumab in Patients With STEMI Undergoing Primary PCI (EPIC STEMI)

ST Elevation Myocardial Infarction | Dyslipidemias | Hypercholesterolemia | Hyperlipidemias | Acute Coronary Syndrome | Physiological Effects of Drugs

Canada
Hillel Yaffe Medical Center

Unknown

Safety of Formalin-free Fixatives for In-Vivo Fixation of Skin Lesions.

Skin Abnormality

Israel
NICHD Global Network for Women's and Children's...
University of Colorado, Denver; University of Alabama at Birmingham; University... and other collaborators

Completed

First Bites: Complementary Feeding - A Global Network Cluster Randomized Controlled Trial (First Bites)

Complementary Feeding | Infant Growth

Congo, Guatemala, Pakistan, Zambia
China Academy of Chinese Medical Sciences
National Natural Science Foundation of China

Recruiting

Effectiveness of Yiqi Fumai Lyophilized Injection for Acute Heart Failure (AUGUST-AHF)

Acute Heart Failure | Chinese Medicine | Complementary Medicine

China
Vancouver Island Health Authority

Unknown

Lyophilized Fecal Microbiota Transplantation for Recurrent Clostridium Difficile Infection

Clostridium Difficile Infection

Canada
Shanghai Tong Ren Hospital
China Cardiovascular Association

Recruiting

Impact of Early PCSK9 Inhibitor Treatment on Heart After Acute Myocardium Infarction

Acute Myocardial Infarction

China
Regeneron Pharmaceuticals
Sanofi

Completed

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Hypercholesterolemia

United States, Bulgaria, Chile, Estonia, Japan, Mexico, Russian Federation, South Africa, Ukraine
The University of Texas Health Science Center,...
Kelsey Research Foundation; Roderick MacDonald Research Fund at Baylor St.... and other collaborators

Completed

Fecal Microbiota Transplantation to Treat Recurrent C. Difficile Associated Diarrhea Via Retention Enema or Oral Route

C. Difficile

United States
Federal University of São Paulo
University of Sao Paulo; Sorocaba Eye Bank

Completed

Lamellar Transplant With Lyophilized Corneas

Keratoconus

Brazil
University of Virginia
Northwestern University

Completed

A Trial of Alirocumab and Plaque Regression in Peripheral Arterial Disease

Peripheral Arterial Disease

United States
Regeneron Pharmaceuticals
Sanofi

Terminated

Long Term Safety Study of PRALUENT

Heterozygous Familial Hypercholesterolemia | Non-familial Hypercholesterolemia

United States, Bulgaria, Estonia, Russian Federation, South Africa, Ukraine
Washington University School of Medicine

Completed

Alirocumab and Reverse Cholesterol Transport

Atherosclerosis | Coronary Heart Disease

United States
HemCon Medical Technologies, Inc

Completed

The Safety of Autologous Lyophilized Plasma Versus Fresh Frozen Plasma in Healthy Volunteers

Healthy

United States
Windtree Therapeutics
Momentum Research, Inc.

Active, not recruiting

The Safety and Efficacy of Istaroxime for Pre-Cardiogenic Shock (SEISMiC)

Cardiogenic Shock

United States, Italy, Poland, Argentina
University of Sao Paulo

Unknown

Comparative Study Between Lyophilized or Frozen Bone Allografts for Sinus-lifting

Disorder of Maxillary Sinus | Accessory; Bone | Bone Atrophy
University Hospital Inselspital, Berne
Regeneron Pharmaceuticals

Completed

Vascular Effects of Alirocumab in Acute MI-Patients (PACMAN-AMI)

Coronary Circulation | Atheroma; Myocardial | Coronary Vessel

Denmark, Switzerland, Austria, Netherlands
University of Southampton
University Hospital Southampton NHS Foundation Trust

Unknown

A Controlled Study to Assess Safety, Colonisation and Immunogenicity of Reconstituted Lyophilised Neisseria Lactamica (Lac5-Nasal)

Meningitis, Bacterial

United Kingdom
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy (ODYSSEY ESCAPE)

Heterozygous Familial Hypercholesterolemia

United States, Germany
Regeneron Pharmaceuticals
Sanofi

Terminated

Praluent® (Alirocumab) Pregnancy Exposure Registry: An OTIS Pregnancy Surveillance Study

Hypercholesterolemia

United States
Regeneron Pharmaceuticals
Sanofi

Completed

A Study of Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

Hypercholesterolemia

France, United States
Regeneron Pharmaceuticals
Sanofi

Completed

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Hypercholesterolemia | Heterozygous Familial Hypercholesterolemia

United States, Canada
Regeneron Pharmaceuticals
Sanofi

Completed

Study in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ODYSSEY HoFH)

Homozygous Familial Hypercholesterolemia

United States, South Africa, Canada, Greece, Japan, Ukraine, Austria, Czechia, France, Germany, Italy, Taiwan, Turkey
GlaxoSmithKline

Completed

Immunogenicity, Reactogenicity and Safety Study of Two Different Formulations of GSK Biologicals' Human Rotavirus Vaccine, Rotarix, in Healthy Infants

Rotavirus

India
AstraZeneca

Completed

To Assess the Effect of Administration of 2 Formulation of AZD3241 on Blood Concentration in Healthy Volunteers

Parkinson's Disease

United Kingdom
Janssen Sciences Ireland UC

Completed

Study to Evaluate Taste Profile of Different JNJ-53718678 Oral Liquid Formulations in Healthy Participants

Healthy

United Kingdom
Kobe University

Recruiting

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy (POLARIS)

Coronary Artery Disease Progression

Japan
THEVAX Genetics Vaccine
Clinical Research Management, Inc.

Unknown

Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSIL

Human Papillomavirus | High-Grade Squamous Intraepithelial Lesions

United States
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Air Force Military Medical University, China; Guangxi Center for Disease Control... and other collaborators

Completed

Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis

Tuberculosis

China
GlaxoSmithKline

Completed

Firategrast (SB683699) Surface Area Study in Multiple Sclerosis Patients

Multiple Sclerosis

Poland, Germany, Czechia
Pfizer

Completed

Single Dose Study To Compare Pharmacokinietics Of 3 Different Formulations Of PF-04991532 In Healthy Volunteers

Healthy

Singapore
Kobe University

Unknown

The Efficacy of Alirocumab for Thin-cap fIbroatheroma in Patients With Coronary Artery Disease Estimated by Optical Coherence Tomography (ALTAIR)

Coronary Artery Disease | Thin-cap fIbroatheroma

Japan
Sanofi
Regeneron Pharmaceuticals

Completed

Pharmacokinetic of Alirocumab SAR236553 (REGN727) Administered Subcutaneously at 3 Different Injection Sites in Healthy Subjects

Hypercholesterolemia

United Kingdom
GlaxoSmithKline

Completed

Bioequivalence and Food Effect Study in Healthy Volunteers

Sleep Initiation and Maintenance Disorders

Italy
Lyndra Inc.

Completed

Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules in Healthy Adults

Healthy | Gastric Retention

Australia
ViiV Healthcare

Recruiting

A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants

HIV Infections

United Kingdom
Nantes University Hospital
Regeneron Pharmaceuticals

Completed

Effect of Alirocumab on Postprandial Hyperlipemia in Patients With Type 2 Diabetes (EUTERPE)

Type2 Diabetes

France
Regeneron Pharmaceuticals
Sanofi

Completed

Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1)

Hypercholesterolemia

United States, Bulgaria, Canada, Norway, Israel, Slovakia, United Kingdom, Hungary
HemCon Medical Technologies, Inc

Withdrawn

A Clinical Study of Lyophilized Plasma in Patients on Warfarin

Anticoagulant Therapy

Search clinical trials for: Alirocumab (Lyophilized formulation)

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