Search clinical trials for: Alovudine

Total 85 results

Boehringer Ingelheim

Completed

Study to Determine the Antiviral Activity and Safety of Alovudine in Nucleoside-experienced HIV-infected Subjects Experiencing Virologic Failure

HIV Infections
Shanghai Henlius Biotech
Huashan Hospital; Shanghai Fosun Pharmaceutical Industrial Development Co....

Not yet recruiting

Real-world Study Evaluating the Efficacy and Safety of Azvudine in Nursing Home Patients

COVID-19
Lederle Laboratories

Completed

A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)

HIV Infections

United States
Bukwang Pharmaceutical

Terminated

Safety and Antiviral Activity Study of Clevudine 30 mg QD in Patient With Chronic HBV

Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Terminated

Safety and Antiviral Activity of Clevudine in Patients Infected With Hepatitis B Virus

Hepatitis B

Korea, Republic of
VistaGen Therapeutics, Inc.

Completed

PH94B in the Treatment of Adjustment Disorder With Anxiety

Adjustment Disorder With Anxious Mood

United States
Lederle Laboratories

Completed

An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
Bukwang Pharmaceutical

Completed

A Clinical Trial to Investigate the Pharmacokinetic Drug-drug Interaction of Clevudine and Adefovir Dipivoxil After Oral Administration in Healthy Male Subjects (BKP-1003-101)

Healthy

Korea, Republic of
Peking Union Medical College Hospital

Not yet recruiting

Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness

COVID-19 Respiratory Infection
Triangle Pharmaceuticals

Unknown

A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus.

Hepatitis B

United States, Canada, China, France, Singapore
Lederle Laboratories

Completed

An Open-Label, Crossover Study to Assess the Effect of Food on the Oral Bioavailability and Pharmacokinetic Profile of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
National Taiwan University Hospital

Unknown

18F-FLT PET for Suspicious Findings on Mammography and Breast Ultrasound

Breast Neoplasms

Taiwan
AHS Cancer Control Alberta

Terminated

A Study to Demonstrate the Safety and Preliminary Efficacy of 18F-FLT in Patients With Solid Tumours or Lymphoma

Lymphoma | Cancer | Solid Tumor | Brain Cancer

Canada
Bukwang Pharmaceutical

Completed

An Open Study to Evaluate the Efficacy, Safety of Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

18F-FLT-PET in Breast Cancer (MK-0000-139)

Breast Cancer
French National Agency for Research on AIDS and...
Gilead Sciences; Pharmasset

Terminated

ANRS HB 05 Multicenter Study Evaluating Efficacy and Safety of Clevudine Monotherapy Versus Tenofovir Monotherapy Versus Combination Therapy of Clevudine and Tenofovir for 96 Weeks in HBeAg Negative Patients With Chronic Hepatitis B, naïve to Anti-VHB Therapy

HBe Negative Chronic Hepatitis B | Hepatitis B Viral Infection

France
European Organisation for Research and Treatment...

Unknown

Evaluation of FLT-PET and DWI-MRI in Patients With NSCLC Treated With a Platinum-based Doublet as Preoperative Chemo (EVIDENCE)

Non-small Cell Lung Carcinoma

Italy, United Kingdom
University of Wisconsin, Madison

Terminated

Pilot Study of 18F-FLT PET

Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Prostate Cancer | CNS Brain Metastasis

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

PET/CT in Evaluating Response to Chemotherapy in Patients With Breast Cancer

HER2-positive Breast Cancer | Stage IV Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer

United States
Siemens Molecular Imaging

Completed

Phase I, Open Label, Single Center Safety Study of [F-18]FLT

Brain Cancer

United States
Dana-Farber Cancer Institute
Boston Children's Hospital

Terminated

A Pilot Study of 18F-FLT in Pediatric Patients With Central Nervous System (CNS) Tumors (FLT)

Tumors of the Central Nervous System

United States
Radboud University Medical Center

Terminated

Validation of 18F-MISO-PET and 18F-FLT-PET

Head and Neck Neoplasms

Netherlands
Fifth Affiliated Hospital, Sun Yat-Sen University

Active, not recruiting

Risk Factors for Severe Disease in Hospitalized Patients With COVID-19 and the Effect of Azvudine Treatment: a Retrospective Cohort Study

COVID-19

China
Qianfoshan Hospital

Recruiting

An Observational, Ambispective Cohort Study of Azvudine in the Treatment of Patients With COVID-19 Pneumonia

COVID-19 Respiratory Infection

China
Bukwang Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Clevudine and Peg-interferon in Sequence Compared With Clevudine Alone in the Patients With HBeAg(+) Chronic Hepatitis B or Clevudine and Peg-interferon Sequential Treatment in Patients With Chronic Hepatitis B Who Have HBeAg(+)

HBeAg(+) Chronic Hepatitis B

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Completed

18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain

Metastatic Breast Cancer to the Brain

United States
Bukwang Pharmaceutical

Completed

Long-term Study With Clevudine

Chronic Hepatitis B

Korea, Republic of
Southeast University, China
Hohhot First Hospital, Hohhot, Inner Mongolia, China

Recruiting

The Efficacy of Azvudine and Paxlovid in High-risk Patients With COVID-19: A Prospective Randomized Controlled Trial

SARS-CoV-2 Infection

China
Bukwang Pharmaceutical

Completed

Switching Study From Lamivudine to Clevudine in the Chronic Hepatitis B Patients

Chronic Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Completed

Compare the Efficacy and Safety of 48-week Treatment With Clevudine 30mg Versus Lamivudine 100mg for CHB Infection

Hepatitis B

Hong Kong
Shanghai Henlius Biotech
Huashan Hospital; Shanghai Fosun Pharmaceutical Industrial Development Co.... and other collaborators

Recruiting

Evaluate the Efficacy and Safety of Azvudine in Preventing SARS-Cov-2 Infection in Ousehold in China

COVID-19

China
HRH Pharmaceuticals Limited
GALZU INSTITUTE OF RESEARCH, TEACHING, SCIENCE AND APPLIED TECHNOLOGY, Brazil and other collaborators

Completed

Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected)

COVID-19

Brazil
HRH Pharmaceuticals Limited
GALZU INSTITUTE OF RESEARCH, TEACHING, SCIENCE AND APPLIED TECHNOLOGY, Brazil and other collaborators

Completed

Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (SARS-CoV-2 Infected)

COVID-19

Brazil
Bukwang Pharmaceutical

Completed

The Proof of Concept Phase 2 Study to Evaluate the Safety and Efficacy of Clevudine in Patients With Mild and Moderate COVID-19

COVID-19

Korea, Republic of
Bukwang Pharmaceutical

Terminated

Safety and Efficacy Study of Retreated Clevudine in Chronic HBV Patients Who Received Clevudine in L-FMAU-201

Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Completed

The Phase 2 Study to Evaluate the Safety and Efficacy of Clevudine in Patients With Moderate COVID-19

COVID-19

Korea, Republic of
Bukwang Pharmaceutical

Terminated

Safety and Antiviral Activity Study of Clevudine 30 mg QD in Patients With HBeAg(-) Chronic HBV

Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Terminated

A Study to Evaluate the Efficacy and the Change of sAg Levels in Chronic Hepatitis B Patients Receiving Clevudine Treatment Over the Long Period

Chronic Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Terminated

Safety and Efficacy Study of L-FMAU in Chronic HBV Patients of L-FMAU-201 Placebo Group

Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Terminated

A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
Shanghai Henlius Biotech
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.; HeNan Sincere...

Recruiting

Evaluate the Efficacy and Safety of Azvudine in Preventing SARS-Cov-2 Infection in Household Contacts of Covid-19

SARS-CoV-2 Infection

Malaysia, Philippines
Abramson Cancer Center of the University of Pennsylvania

Withdrawn

Positron Emission Tomography in Monitoring Treatment Response in Women With Newly Diagnosed Breast Cancer

Adult Women With a New Diagnosis of Invasive Breast Cancer (Have Not Undergone Treatment)
Bukwang Pharmaceutical

Completed

A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Proportion to Roadmap Concept in Patients With HBV Associated-HCC

Hepatitis B Associated Hepatocellular Carcinoma

Korea, Republic of
Biosense Webster EMEA

Completed

FLAT Study: First Line Ablation Therapy for Treatment of Paroxysmal Atrial Fibrillation (RAAFT)

Atrial Fibrillation

Italy
Bukwang Pharmaceutical

Terminated

Safety and Antiviral Activity of Clevudine in Patients Who Have Completed the L-FMAU-301 or L-FMAU-302 Trials

Hepatitis B

Korea, Republic of
University Hospital, Angers
University Hospital, Rouen; Central Hospital, Nancy, France; University Hospital... and other collaborators

Unknown

Theranostic Tool During Erlotinib Treatment in Non-small Cell Lung Cancer Patient (FLT-THERA)

Non-small Cell Lung Cancer Metastatic or Non-small Cell Lung Cancer Recurrent | No EGFR Activating Mutation

France
Angiochem Inc

Completed

GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases (GRABM-B)

Breast Cancer | Brain Metastases

United States
Inje University
Bukwang Pharmaceutical

Terminated

Efficacy of Clevudine Plus Lamivudine for Lamivudine-resistant Chronic Hepatitis B Patients

Chronic Hepatitis B

Korea, Republic of
Bukwang Pharmaceutical

Terminated

A Study to Compare and Evaluate Intrahepatic cccDNA Reduction After Administrating Clevudine or Entecavir in the Chronic HBV Patients

Chronic Hepatitis B

Korea, Republic of
Weill Medical College of Cornell University
William Rhodes Center for Glioblastoma

Recruiting

Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma

Glioma

United States

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