Search clinical trials for: Alpha-Methyltyrosine

Total 6979 results

Genentech, Inc.

Completed

A Drug Interaction Study of GDC-0032 Co-administered With Rifampin or Itraconazole in Healthy Volunteers

Healthy Volunteer

United States
Masoud Saatchi

Completed

Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis

Local Anesthesia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)

Lung Diseases | Respiratory Distress Syndrome, Adult

United States, Canada
Anders Rane, MD, PhD, Senior professor
Karolinska University Hospital

Completed

Safety of Fluconazole Treatment of Premature and Full-term Newborn Infants

Bacterial Infections and Mycoses | Ductus Arteriosis, Patent

Sweden
Nexgen Pharma, Inc

Completed

Single Dose Trial of Extended Release Combination Tablet Codeine and Guaifenesin

Cough

Jordan
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, PK and PD of SCH 900518 in Naive or Treatment-Experienced Subjects Infected With HCV Genotype 1 (Protocol No. P04695)

Hepatitis C, Chronic
Celgene

Recruiting

A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants

Healthy Volunteers

United States
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects

Healthy Subjects

China
Washington University School of Medicine
The Leukemia and Lymphoma Society; Rising Tide Foundation; St. Louis Children...

Not yet recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML (ABCD-NK)

Acute Myeloid Leukemia | Aml | AML, Childhood | Acute Myeloid Leukemia, Pediatric

United States
Damascus University

Recruiting

The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA

Pain | Arthroplasty Complications | Arthritis Knee

Syrian Arab Republic
Minia University

Recruiting

Articaine Efficiency in Pulpectomy of Children With Irreversible Pulpitis Under the Age of Four

Dental Pulp Diseases

Egypt
Dizal Pharmaceuticals

Recruiting

Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine

Healthy Subjects

United States
Chinese University of Hong Kong

Recruiting

Prospective RCT Lidocaine & Levobupivacaine on Block Dynamics After Subparaneural Popliteal Sciatic Nerve Block

Musculoskeletal Diseases or Conditions

Hong Kong
Celgene

Terminated

A Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's Lymphomas

Neoplasms | Lymphoma, Non-Hodgkin

France, Italy, Japan, Spain, United Kingdom
BeiGene

Completed

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

B-cell Malignancies

Australia
Epizyme, Inc.

Completed

Study to Describe the Interaction Between Tazemetostat and Itraconazole and Between Tazemetostat and Rifampin in Participants With Advanced Cancer

Solid Tumor | Mesothelioma | Rhabdoid Tumor | Hematologic Malignancy | Advanced Malignancies | Synovial Sarcoma | Renal Medullary Carcinoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Non-Hodgkin Lymphoma (NHL) | All Malignancies | Epithelioid Sarcoma (ES)

Spain, United States
Jazz Pharmaceuticals

Completed

An Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics (PK) of Sativex® in Healthy Subjects With Cannabis Experience.

Healthy Subjects

United States
Pfizer

Completed

A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001

Fungal Infection

Netherlands
Ciceri Fabio

Completed

Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole (SIR-POSA)

Myelodysplastic Syndromes | Fungal Infection | Graft Vs Host Disease | Leukemia, Acute | Transplant-Related Hematologic Malignancy

Italy
Beijing InnoCare Pharma Tech Co., Ltd.

Completed

DDI Study of Orelabrutinib

Healthy Person

China
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of Itraconazole, Phenytoin and Gemfibrozil on the Drug Levels of BMS-986166 in Healthy Participants

Healthy Participants

United States
AnHeart Therapeutics Inc.

Completed

A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK

Solid Tumor

China
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effects of Itraconazole and Rifampin on Selpercatinib (LY3527723) in Healthy Participants

Healthy

United States
University of Florida
ALS Association; Holy Cross Hospital, Florida

Completed

Impact of Nuedexta on Bulbar Physiology and Function in ALS

Amyotrophic Lateral Sclerosis

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery

Sarcoma

United States
Azienda Ospedaliero, Universitaria Pisana

Completed

Zinc as Enhancer in Immune Recovery After Stem Cell Transplantation for Hematological Malignancies (ZENITH)

Stem Cell Transplant Complications

Italy
Northwestern University

Completed

Selective Intraoperative Administration of Local Anesthesia in Breast Reconstruction

Breast Cancer

United States
Bayer
Orion Corporation, Orion Pharma

Completed

Drug-drug Interaction (DDI) Study to Assess ODM-201 as a Victim of CYP3A4 Inhibition or Induction

Biological Availability

Germany
Mahidol University

Unknown

Efficacy of Adrenaline in Periarticular Analgesic Injection on Postoperative Pain Control After Total Knee Arthroplasty

Postoperative Pain

Thailand
Holy Cross Hospital, Florida

Withdrawn

A Comparison of Exparel Local Anesthetic in Total Knee Arthroplasty (TKA) Patients

Osteoarthritis, Knee | Arthroplasty, Replacement, Knee

United States
Avanir Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment

Depressive Disorder, Treatment-Resistant

United States
Avanir Pharmaceuticals

Completed

A Phase 1 Study Comparing AVP-786 With AVP-923

Healthy Volunteer

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of Intradermal Quadrivalent Influenza Vaccine in Adults Aged 18 Through 64 Years

Influenza

United States
Vanda Pharmaceuticals

Completed

Pharmacokinetics of Tasimelteon Alone and in Combination With a CYP3A4 Inhibitor, Ketoconazole, or a CYP3A4 Inducer, Rifampin.

Healthy

United States
Islamic Azad University, Tehran

Completed

Effect of Fentanyl on the Rate of Anesthesia

Painful Irreversible Pulpitis

Iran, Islamic Republic of
Seoul National University Hospital

Completed

Periarticular Multimodal Drug Injections in Total Knee Arthroplasty

Osteoarthritis, Knee

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Coxa, Hospital for Joint Replacement

Unknown

Local Infiltration Analgesia During Total Knee Arthroplasty (LIA)

Pain

Finland
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers

Essential Hypertension
University of Manchester
Manchester University NHS Foundation Trust

Completed

Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery

Postoperative Pain | Wisdom Tooth

United Kingdom
Michael Schneider, DC, PhD
Patient-Centered Outcomes Research Institute

Completed

Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)

Lumbar Spinal Stenosis

United States
Hospital de Clinicas de Porto Alegre

Unknown

Interpersonal Psychotherapy for Treatment Resistant Depression

Treatment Resistant Depression

Brazil
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Asceneuron S.A.

Recruiting

Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects

Drug Drug Interaction

Netherlands
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets

Myelofibrosis

China
Boehringer Ingelheim

Recruiting

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Solid Tumors

Spain, Belgium
Children's Hospital of Eastern Ontario
The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Alberta Children's Hospital Research Institute and other collaborators

Recruiting

Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study (BIPED)

Bronchiolitis

New Zealand, Canada, Australia
The University of Texas Health Science Center at...

Completed

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

Periodontal Diseases

United States
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Jaktinib in Healthy Volunteers

Healthy Volunteers

China

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