Search clinical trials for: Anti-TNF-alpha

Total 91619 results

Huashan Hospital
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

Real-world Study Optimizing Nucleotide-analogues

Hepatitis B, Chronic

China
Universidade Federal do Rio de Janeiro

Unknown

99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity

Arthritis | Psoriatic Arthritis

Brazil
Assistance Publique - Hôpitaux de Paris

Unknown

The RATIO: Registry of Infections and Lymphoma in Patients Treated With TNF-a Antagonists

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Ankylosing Spondylitis

France
Rigshospitalet, Denmark
University of Copenhagen; Copenhagen Muscle Research Centre, Rigshospitalet...

Completed

The Acute Effects of Low-dose TNF-α on Glucose Metabolism and β-cell Function in Humans

Diabetes Type 2

Denmark
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease

Hepatocellular Carcinoma | Chronic Liver Disease

Taiwan
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Genetic Polymorphisms of Interleukin-1B and TNF-A and HBV-Related Hepatocellular Carcinoma

Hepatitis B | Hepatocellular Carcinoma | Chronic Liver Disease

Taiwan
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Inflammatory Bowel Disease | Ankylosing Spondylitis
Central Hospital, Nancy, France

Completed

C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France

Arthritis, Rheumatoid | Arthritis, Psoriatic | Spondylitis, Ankylosing | Arthitis, Juvenile Idiopathic

France
Neovacs

Completed

Immunogenicity and Safety of TNFa Kinoid in Rheumatoid Arthritis With Secondary Resistance to TNFa Antagonists

Rheumatoid Arthritis

Belgium, France, Bulgaria, Argentina, Croatia, Chile, Romania
Medical University of Graz

Completed

Long-term Outcome of TNF Alpha Therapy in IBD

IBD

Austria
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)

HBV | Chronic HBV Infections

China
Gilead Sciences

Completed

Study to Evaluate Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically Suppressed

Chronic Hepatitis B

United States, Canada, United Kingdom, Hong Kong, Spain, Taiwan, Korea, Republic of, Italy
Gilead Sciences

Completed

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Negative for Hepatitis B e Antigen

HBeAg-negative Chronic Hepatitis B

Hong Kong, United States, United Kingdom, Canada, Australia, Spain, Taiwan, India, Japan, Poland, Romania, Russian Federation, Korea, Republic of, Italy, New Zealand, France, Turkey
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)

HBV | Chronic HBV Infections

China
Hamamatsu University
Yokoyama Foundation for Clinical Pharmacology

Unknown

Cytokine Gene Polymorphisms in Gastric Diseases

Gastric Cancer | Gastric Ulcer | Duodenal Ulcer

Japan
Gilead Sciences

Completed

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen

HBeAg-positive Chronic Hepatitis B

Hong Kong, Korea, Republic of, United States, Taiwan, United Kingdom, France, Australia, Spain, Bulgaria, Canada, India, Italy, Japan, New Zealand, Poland, Romania, Russian Federation, Singapore, Turkey
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease

Hepatitis C Virus Infection | Chronic Liver Disease

Taiwan
HaEmek Medical Center, Israel
University of Toronto; Mount Sinai Hospital, Canada

Completed

The Influence of Biologcal Treatment on the Short-Term Complications of Surgery in Patients With Inflematory Bowel Disease.

Ulcerative Colitis | Anti TNF Therapy | Ileal Pouch Anal Anastomosis (IPAA)
Takeda

Completed

Sub-optimal Response to Anti-Tumor Necrosis Factor's in Inflammatory Bowel Disease in Emerging Markets

Inflammatory Bowel Diseases | Crohn Disease | Colitis, Ulcerative

China, Korea, Republic of, Taiwan, Russian Federation, Turkey, Argentina, Colombia, Mexico, Saudi Arabia, Singapore
Pfizer

Completed

Correlation Between Beliefs About Medicine and Objective Measures of Efficacy and Safety in Rheumatoid Arthritis (RA) (CONTENT)

Rheumatoid Arthritis

Belgium
Protalix

Completed

Study to Evaluate the Safety and Pharmacokinetics of Oral OPRX-106 (TNFR-Fc Fusion Protein) in Healthy Volunteers

Human Volunteer

Israel
European Organisation for Research and Treatment...

Completed

NGR-TNF in Treating Patients With Advanced Solid Tumors

Kidney Cancer | Head and Neck Cancer | Colorectal Cancer | Unspecified Adult Solid Tumor, Protocol Specific

Germany, Netherlands
Pfizer

Completed

Study Looking at Longitudinal Changes in Fatigue and Health Status in Rheumatoid Arthritis (RA) Patients Treated With Subcutaneous Anti-TNF-α Therapy

Rheumatoid Arthritis

Belgium
Hospital del Río Hortega
Francisco Javier Garcia Alonso; Jesús Barrio

Recruiting

Influence of HLA-DQA1*05 Genotype in Adults With Anti-TNF Treatment With Proactive Therapeutic Drug Monitoring. (Proa-DQ)

Inflammatory Bowel Diseases | Drug Monitoring

Spain
Shanghai Public Health Clinical Center
Yunnan AIDS Care Center; Xixi Hospital of Hangzhou

Active, not recruiting

Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection

HIV-1-infection

China
Beijing Ditan Hospital

Unknown

Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B

Chronic Hepatitis B Infection | High Viral Load

China
Gilead Sciences

Completed

Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF

HIV-1 Infection

United States, United Kingdom, Canada, France, Italy, Puerto Rico, Belgium
Prof. Roberto Giacomelli

Terminated

Clinical Study to Evaluate the Efficacy of Anakinra in Patients With Rheumatoid Arthritis and Diabetes (TRACK)

Diabetes Mellitus, Type 2 | Arthritis, Rheumatoid

Italy
Shanghai Zhongshan Hospital

Recruiting

A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu Arteritis | Treatment | Tocilizumab | Adalimumab

China
NHS Greater Glasgow and Clyde
University of Glasgow; NHS Ayrshire and Arran; Golden Jubilee National Hospital

Not yet recruiting

CharacterisatiON of carDiac funCTion in Intensive Care Unit Survivors of Sepsis. (CONDUCT-ICU)

Heart Failure | Sepsis | Septic Shock | Myocarditis

United Kingdom
Children's Hospital Medical Center, Cincinnati
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Determining Predictors of Safe Discontinuation of Anti-TNF Treatment in JIA

Juvenile Idiopathic Arthritis

United States
Hospital Universitari Vall d'Hebron Research Institute
UCB Pharma

Unknown

Serum Biomarkers Analysis in Patients With AR Treated With Anti-TMF (AROMA)

Rheumatoid Arthritis

Spain
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Relationship Between Polymorphism of Heat Shock Protein 70 Gene and Hepatocellular Carcinoma (HSP70)

Hepatocellular Carcinoma

Taiwan
Cairo University

Completed

Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical Study

Uveitis | Behçet's Disease
Janssen Biotech, Inc.

Completed

Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database

Psoriasis
Aarhus University Hospital
University of Aarhus; Lundbeck Foundation

Completed

Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?

Glucose Metabolism Disorders | Inflammation

Denmark
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of E/C/F/TAF Versus E/C/F/TDF in HIV-1 Positive, Antiretroviral Treatment-Naive Adults

HIV Infections | HIV

United States, United Kingdom, Sweden, France, Puerto Rico, Netherlands, Italy, Portugal, Canada, Mexico, Dominican Republic
All India Institute of Medical Sciences, New Delhi

Completed

Effect Of Anti TNF Alpha Therapy And Their Adverse Effects In Ankylosing Spondylitis In A North Indian Population

Ankylosing Spondylitis

India
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Belgium, Israel, India, Korea, Republic of, Netherlands, Singapore, Brazil, Russian Federation, New Zealand, Hungary, Norway, Australia, Egypt, Hong Kong, Malaysi...
Gilead Sciences

Completed

Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

HIV Infections | Acquired Immunodeficiency Syndrome

United States, Puerto Rico
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults

HIV Infections | HIV

United States, Spain, Switzerland, Canada, Thailand, Puerto Rico, Australia, Austria, Belgium, Italy, Japan, United Kingdom
University Hospital, Lille

Withdrawn

Comparing the Quality of Life of Terminal Ileitis Patients With Crohn's Disease Treated With Anti-TNF or Surgical Resection (CASINO)

Quality of Life
University of Campinas, Brazil

Completed

Effects of the TNF-alpha Inhibiton on Hemodynamic Parameters in Resistant Hypertension

Hypertension

Brazil
Centre Hospitalier Universitaire de Nīmes
Pfizer

Completed

Evaluation of Tumour Necrosis Factor Alpha (TNFα) Blockers in Early Rheumatoid Arthritis in France

Rheumatoid Arthritis
Gilead Sciences

Completed

Safety and Efficacy of Switching to a FDC of B/F/TAF From E/C/F/TAF, E/C/F/TDF, or ATV+RTV+FTC/TDF in Virologically Suppressed HIV-1 Infected Women

HIV-1 Infection

Russian Federation, United States, Thailand, Uganda, Puerto Rico, Dominican Republic
The Second Affiliated Hospital of Chongqing Medical...
Guizhou Provincial People's Hospital; The Affiliated Hospital Of Southwest...

Not yet recruiting

A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)

Chronic Hepatitis b | Anti-PD-1 Antibody

China
Gilead Sciences

Completed

Study to Evaluate Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants

HIV Infections | HIV

Canada, United States, Spain, Puerto Rico, France, Switzerland, Australia, Germany, United Kingdom, Sweden, Brazil, Austria, Thailand, Netherlands, Belgium, Dominican Republic, Portugal, Italy, Denmark, Mexico
National Institute of Allergy and Infectious Diseases...

Completed

Auranofin PK Following Oral Dose Administration

Amoebiasis

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis (TAWIS)

Sarcoidosis

France
Gilead Sciences

Completed

Efficacy and Safety of Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF)-Containing Regimens in Participants With Chronic Hepatitis B Virus (HBV) Infection and Stage 2 or Greater Chronic Kidney Disease Who Have Received a Liver Transplant

Chronic Hepatitis B

New Zealand

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