Search clinical trials for: anti-VEGF agent

Total 187639 results

Amgen

Completed

Study for Patients Who Have Benefited and Tolerated Prior Panitumumab Treatment

Colorectal Cancer | Non-Small Cell Lung Cancer | Prostate Cancer | Solid Tumors | Advanced Renal Cell Carcinoma
Chang Gung Memorial Hospital

Completed

EGF-loaded Chitosan to Facilitate Healing and Prevent Scar Formation of Cesarean Wound

Cesarean Wound | Scar; Previous Cesarean Section, Complicating Pregnancy or Childbirth, Affecting Fetus or Newborn

Taiwan
University of Alabama at Birmingham
Genentech, Inc.

Completed

Lower Dose Chemotherapy Given More Frequent With Avastin to Treat Advanced Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
Boston Medical Center
Amgen

Withdrawn

Study of Panitumumab in the Treatment of Carcinoid Syndrome

Carcinoid Syndrome

United States
Tennessee Retina
Regeneron Pharmaceuticals

Unknown

Two-week Retreatment Interval Study for Treated Age-related Macular Degeneration Refractory to Monthly Aflibercept (TRISTAR)

Neovascular Age-related Macular Degeneration

United States
Regeneron Pharmaceuticals
Bayer

Completed

Open-label Extension Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Neovascular ("Wet") Age-related Macular Degeneration (AMD)

Neovascular Age-related Macular Degeneration

United States, Canada
National Cancer Institute (NCI)

Recruiting

A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer

Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Stage III Liver Cancer | Stage IV Liver Cancer

United States
Abgenix
Immunex Corporation

Completed

ABX-EGF (a Monoclonal Antibody) Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body

Prostate Cancer

United States
Sanofi
Regeneron Pharmaceuticals

Terminated

Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer (VANILLA)

Pancreatic Neoplasm

United States, France, Canada, Poland, Romania, Russian Federation, Germany, Italy, Spain, Switzerland, Bulgaria, India, Belgium, Czech Republic, Mexico, Argentina, Hungary, Colombia, Slovakia, Chile, Austria, Greece, Puerto Rico, Cyprus
Clearside Biomedical, Inc.

Completed

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD (OASIS)

Neovascular Age-related Macular Degeneration

United States
Benha University

Recruiting

Effect of Corona Virus on Intravitreal Injections

Age-Related Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Choroidal Neovascularization | Myopic Choroidal Neovascularisation

Egypt
Tianjin Medical University Cancer Institute and...

Recruiting

Ivonescimab Combined With HAIC for the Treatment of Unresectable Hepatocellular Carcinoma（uHCC）.

Hepatocellular Carcinoma | Hepatocellular Carcinoma Non-resectable

China
M.D. Anderson Cancer Center

Active, not recruiting

Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC

Triple-Negative Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA... and other conditions

United States
Sun Yat-sen University
Guangdong Provincial Hospital of Traditional Chinese Medicine; Guangdong Provincial...

Active, not recruiting

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Colorectal Cancer | Microsatellite Instability High

China
National Cancer Institute (NCI)

Terminated

Aflibercept for Relapsed Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma

United States
Amgen

Completed

Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy

Colorectal Cancer | Metastatic Cancer
Amgen

Completed

Safety and Efficacy Study of ABX-EGF in Patients With Renal Cancer, Part 2

Advanced Renal Cell Carcinoma
Amgen

Completed

Phase 2 Study of ABX-EGF (Panitumumab) in Japanese Subjects With M-colorectal Cancer

Metastatic Colorectal Cancer
Amgen

Completed

Two Dose Schedules of Panitumumab in Subjects With Advanced Solid Tumors

Solid Tumors | Oncology | Tumors
Shanghai Zhongshan Hospital
Shanghai Henlius Biotech

Not yet recruiting

Combination Therapy of HAIC and HLX10 and HLX04 in HCC With Major Portal Vein Tumor Thrombosis

Hepatocellular Carcinoma With Major Portal Vein Thrombosis
Bayer

Completed

Study to Gather Information on the Safety and Use of Aflibercept Injections Into the Eye for the Treatment of Eye Disorders in Mexican Routine Clinical Practice (MAIA)

Retinal Disease

Mexico
Bayer
Regeneron Pharmaceuticals

Completed

Aflibercept in Polypoidal Choroidal Vasculopathy (PLANET)

Neovascular Macular Degeneration

Taiwan, Hong Kong, Korea, Republic of, Japan, Singapore, Australia, Hungary, Germany
Bayer
Regeneron Pharmaceuticals

Completed

VEGF Trap-Eye: Investigation of Efficacy and Safety in Chinese Subjects With Wet AMD (Age-Related Macular Degeneration)

Macular Degeneration

China
University of Alabama at Birmingham
Genentech, Inc.

Completed

Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas

Neurofibromatosis Type 2 | Progressive Vestibular Schwannomas

United States
Stanford University
Eli Lilly and Company; Genentech, Inc.

Completed

Phase II Bevacizumab, Gemcitabine and Carboplatin in Newly Diagnosed Non-Small Cell Lung Cancer

Lung Cancer | Non-small Cell Lung Cancer (NSCLC)

United States
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

All-trans Retinoic Acid (ATRA) in the Treatment of Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck (Aplus)

Adenoid Cystic Carcinoma of the Head and Neck

China
National Cancer Institute (NCI)

Active, not recruiting

Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer

Sarcoma | Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Recurrent Renal Cell Carcinoma | Recurrent Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Carcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor

Metastatic Renal Cell Carcinoma | Diarrhea | Stage IV Renal Cell Cancer

United States
Centre de recherche du Centre hospitalier universitaire...
Université de Sherbrooke

Recruiting

4FMFES-PET Imaging of Endometrial and Ovarian Cancers

Ovarian Cancer | Endometrial Cancer

Canada
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma (IMplus)

Head and Neck Squamous Cell Carcinoma

China
ZARS Pharma Inc.

Completed

S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Vascular Access Procedures in Children

Pain

United States
Clearside Biomedical, Inc.

Terminated

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO (TOPAZ)

Macular Edema | Retinal Vein Occlusion

United States, India, Australia, Hungary, New Zealand
Daewoong Pharmaceutical Co. LTD.

Completed

DWP708 for Treating Epidermal Growth Factor Receptor Inhibitor Related Skin Toxicities

Rash Acneiform

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

Edema | Erythema | Breast Carcinoma | Invasive Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Inflammatory Breast Carcinoma | Breast Lump | Peau d'Orange

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Bevacizumab and Combination Chemotherapy in Treating Patients With Peripheral T-Cell Lymphoma or Natural Killer Cell Neoplasms

Lymphoma

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom

Ocular Hypertension | Open Angle Glaucoma

United Kingdom
Genentech, Inc.
Hoffmann-La Roche

Recruiting

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

Neoplasm Metastasis

Australia, Korea, Republic of, China, United States, Portugal, Brazil, Peru, Singapore, Spain, United Kingdom, Belgium, Austria, Bulgaria, Canada, Chile, Croatia, Czechia, Denmark, France, Germany, Hong Kong, Hungary, Israel, Italy, Japan, Mexi... and more
Daiichi Sankyo
AstraZeneca; Daiichi Sankyo Co., Ltd.

Active, not recruiting

DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]

Breast Cancer

United States, Canada, Spain, Belgium, China, Italy, Korea, Republic of, Taiwan, Australia, Japan, Brazil, France, Germany, United Kingdom, Hong Kong
National Cancer Institute (NCI)

Completed

Bevacizumab and Combination Chemotherapy in Patients With Lymph Node Positive Breast Cancer

Male Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer

United States
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

Canada
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer

Metastatic Renal Cell Carcinoma

United States, Peru
University Hospital, Bordeaux

Recruiting

Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors (SPICI)

Metastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score

France
Hallym University Medical Center

Unknown

The Effect of Therapy With Bevacizumab in Chronic Central Serous Chorioretinopathy

Central Serous Chorioretinopathy
National Cancer Institute (NCI)

Completed

Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma

Fallopian Tube Cancer | Uterine Carcinosarcoma | Stage IV Ovarian Epithelial Cancer | Ovarian Sarcoma | Recurrent Uterine Sarcoma | Stage III Uterine Sarcoma | Stage IV Uterine Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian Carcinosarcoma | Female Reproductive... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

Aflibercept in Treating Young Patients With Relapsed or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States
University of Southern California
Sponsor Name Pending

Withdrawn

A Study of VEGF-Antisense Oligonucleotide in Combination With Pemetrexed and Cisplatin for the Treatment of Advanced Malignant Mesothelioma

Mesothelioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
Roswell Park Cancer Institute

Recruiting

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

Colo-rectal Cancer

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; Genentech...

Completed

Gemcitabine, Bevacizumab and Erlotinib in Pancreatic Cancer

Pancreatic Cancer | Adenocarcinoma of the Pancreas

United States

Search clinical trials for: anti-VEGF agent

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