Search clinical trials for: Antidepressant SPD489 (Lisdexamfetamine dimesylate) 10 mg

Total 39 results

Shire

Completed

SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States, Chile, Australia, Argentina, United Kingdom
Shire

Completed

Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Completed

Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States, Germany, Sweden, Poland, South Africa, Belgium, Czechia, Estonia, Finland, Hungary, Romania
Shire

Completed

Exploratory Study of SPD489 in Adults With Major Depressive Disorder (MDD) as Augmentation Therapy to an Antidepressant

Major Depressive Disorder

United States
Shire

Completed

Efficacy, Safety, and Tolerability of SPD489 in Adults With Schizophrenia and Predominant Negative Symptoms

Schizophrenia and Predominant Negative Symptoms

United States
Shire

Completed

Safety and Efficacy Study in Preschool Children Aged 4-5 Years With Attention-deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Terminated

Adjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Terminated

SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study

Major Depressive Disorder

United States, Spain, Germany, Puerto Rico, Canada, Estonia, South Africa, Czechia, Finland, Chile, Hungary, Mexico, Poland, Romania
Shire

Completed

Pharmacodynamic Profile of SPD489 in Healthy Adult Males Undergoing a Nocturnal Period of Acute Sleep Loss

Sleep Deprivation

United States
Shire

Withdrawn

SPD489 as Adjunctive Treatment in Adults With Negative Symptoms of Schizophrenia (NSS)

Negative Symptoms of Schizophrenia
Shire

Completed

Safety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

United States
Shire

Completed

Lisdexamfetamine Dimesylate 2-year Safety Study in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

Germany, Italy, Poland, Spain, Romania, Belgium, Hungary, Netherlands, Sweden, United Kingdom
Shire

Completed

Forced-dose Titration of SPD489 in Adults With Binge Eating Disorder (BED)

Binge Eating Disorder

United States
Shire

Completed

Open Label Extension in Adults With Binge Eating Disorder (BED)

Binge Eating Disorder

Spain, United States, Germany
Shire

Completed

Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Spain, Germany, Canada, Sweden
Shire

Completed

Double-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Children and Adolescents Aged 6-17

ADHD

Germany, Hungary, Italy, Poland, Sweden, United States, United Kingdom, Belgium, France
Shire

Completed

SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder

Major Depressive Disorder

United States
Shire

Completed

Assess the Safety and Pharmacokinetics of Ascending, Multiple Oral Doses of SPD489 in Adults With Schizophrenia

Schizophrenia

United States
Shire

Completed

Safety and Tolerability Study of SPD489 in Preschool Children Aged 4-5 Years, Diagnosed With Attention-deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Withdrawn

Safety and Efficacy of SPD489 in Adolescent Subjects Aged 13-17 Years With Attention-Deficit/Hyperactivity Disorder (ADHD)

ADHD

United States
Shire

Completed

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Germany
Shire

Completed

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Spain, Germany, Sweden
Shire

Terminated

SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

Co-Administration of LDX (SPD489) and Venlafaxine XR (EFFEXOR XR) in Healthy Volunteers

Healthy

United States
Shire

Terminated

Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States, Spain, Canada, Puerto Rico, Croatia, Mexico
Shire

Completed

Safety and Efficacy of SPD489 on Executive Function Behaviors in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

ADHD Specifically With Executive Function Impairment

United States
Shire

Completed

Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

Attention-deficit/Hyperactivity Disorder

United States, Canada, Germany, Hungary, Sweden
Shire

Completed

Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

Attention-deficit/Hyperactivity Disorder

United States
Butler Hospital
National Institute of Mental Health (NIMH)

Completed

Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users

Substance-Related Disorders | Depression | HIV Infections

United States
Gregory Fabiano

Completed

Efficacy of Lisdexamfetamine Dimesylate for Promoting Occupational Success in Young Adults With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Shire

Completed

Bioavailability Study of SPD489 Administered With Two Different Means of Administration in Healthy Adult Volunteers

Healthy Volunteers

United States
Neurovance, Inc.

Completed

A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users

Healthy Volunteers | Drug Users

United States
Shire

Completed

Efficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
University of California, Irvine

Completed

The Reinforcing Mechanisms of Smoking in Adult ADHD

ADHD

United States
Rochester Center for Behavioral Medicine
Shire

Completed

Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome

Chronic Fatigue Syndrome | Cognitive Impairments

United States
Amsterdam UMC, location VUmc
ADHDcentraal

Completed

The Day-time Response Variation of (Lis)Dexamphetamine (IDEAL)

Adhd

Netherlands
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Unknown

Follow up Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

Canada
Hospital Universitari de Bellvitge

Terminated

Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression

Depression

Spain

3

Subscribe