Search clinical trials for: Antidiabetic

Total 377 results

Università Vita-Salute San Raffaele

Completed

Desmopressin in Cardiac Surgery

Hemorrhage | Blood Loss, Surgical | Postoperative Hemorrhage

Italy
Otsuka Frankfurt Research Institute GmbH

Unknown

Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice

SIADH | Non-SIADH Hyponatremia | Non-Hyponatremia

Denmark, Germany, Italy, Norway, Spain, Sweden, United Kingdom
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Evaluating the Safety and effectivenesS in Adult KorEaN Patients Treated With Tolvaptan for Management of Autosomal domInAnt poLycystic Kidney Disease (ESSENTIAL)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Korea, Republic of
Azevan Pharmaceuticals
United States Department of Defense; Weill Medical College of Cornell University and other collaborators

Terminated

Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD

PTSD

United States
Yonsei University

Unknown

Vasopressin Injection Technique to Preserve Ovarian Reserve in Surgery for Unilateral Ovarian Endometriomas

Unilateral Ovarian Endometrioma

Korea, Republic of
Otsuka Pharmaceutical Development & Commercialization...

Completed

Short-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

Netherlands
Otsuka Pharmaceutical Co., Ltd.

Completed

A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001]

Autosomal Dominant Polycystic Kidney Disease

Japan
University of California, Los Angeles

Completed

Vasopressin and the Social Brain

Social Psychology

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Trial of OPC-41061 in Patients With Hepatic Edema - Investigation of the Safety of Treatment at 7.5 mg Beyond 7 Days and of the Effect of Dose Escalation to 15 mg

Cirrhosis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Open-label Dose-finding Trial of OPC-41061 in Patients With Chronic Renal Failure Undergoing Peritoneal Dialysis

Chronic Renal Failure

Japan
Columbia University
Astellas Pharma Inc

Withdrawn

Safety and Efficacy of Conivaptan for the Correction of Hyponatremia in Neurological Patients

Hyponatremia

United States
University of Aarhus
Ferring Pharmaceuticals

Completed

The Effect of Gender on Antidiuresis - Evaluated by Graded Low Dose Desmopressin Infusion

Nocturnal Enuresis | Nocturia | Gender Difference in V2 Receptor Function in Response to dDAVP Infusion

Denmark
Otsuka Beijing Research Institute

Completed

Multiple-dose Pharmacokinetics Study of Tolvaptan Tablets in Chinese Patients With Hepatocirrhosis

Ascites | Hepatic Cirrhosis

China
Sanofi

Completed

Satavaptan Dose-Ranging Study in the Prevention of Ascites (SPA)

Liver Cirrhosis | Ascites

France, Germany, Italy, Spain, Taiwan, Belgium, Czech Republic, Argentina, Croatia, Canada, Australia
Icahn School of Medicine at Mount Sinai

Completed

Prevention of Bleeding in Patient With Cirrhosis Undergoing Dental Extraction

Liver Cirrhosis | Coagulopathy

United States
Sanofi

Completed

Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Hyponatremia | Inappropriate ADH Syndrome

United States, Canada, Brazil, Germany, Netherlands, Portugal, Spain, Belgium, Croatia, Hungary, Hong Kong
Sanofi

Completed

DILIPO (DILutIonal HyPOnatremia)

Congestive Heart Failure

United States, Canada, Poland, Romania, Portugal, Sweden, Belgium, Argentina, Denmark, Hungary, Israel, Australia, Chile, South Africa, Greece
Turkish Metabolic Surgery Foundation

Unknown

Surgical Intervention for the Treatment of Diabetes in Overweight Non-responders-1 (SIT-DOWN-1)

Diabetes Mellitus, Type 2 | Overweight
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy and Safety of Vasopressin Versus Terlipressin as a Second Vasopressor in Critically Ill Cirrhotics With Septic Shock- the VITEL-C Trial

Septic Shock | Cirrhosis, Liver

India
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH

Antidiuretic Hormone, Inappropriate Secretion

Japan
University Hospital, Ghent

Completed

Desmopressin Melt Therapy in Nocturnal Polyuria Patients: Pharmacodynamic Study

Nocturia

Belgium
University of North Carolina, Chapel Hill
Otsuka America Pharmaceutical

Completed

Tolvaptan For Worsening Outpatient Heart Failure: Role of Copeptin In Identifying Responders (TROUPER)

Congestive Heart Failure

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Tolvaptan Extension Study in Participants With ADPKD (TEMPO 4/4)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States, Australia, Belgium, Germany, Italy, Poland, Romania, United Kingdom, Argentina, Canada, France, Netherlands, Russian Federation
Otsuka Pharmaceutical Development & Commercialization...

Completed

Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Belgium, Germany, Italy, Spain, Sweden, United States, Canada, Australia, Netherlands, Czechia, Poland, Denmark, Israel, Hungary, Russian Federation, South Africa, United Kingdom, Romania, Argentina, Norway
Otsuka Pharmaceutical Co., Ltd.

Completed

Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients

Heart Failure

Japan
University Hospital, Ghent

Completed

Influence of Food-intake on Desmopressin Oral Tablets and MELT-formulation (TM)

Enuresis | Polyuria

Belgium
Medical University of South Carolina
Emory University

Completed

Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant

Liver Failure

United States
Sanofi

Terminated

A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia (AQUARIST1)

Hyponatremia | Inappropriate ADH Syndrome

United States
Cumberland Pharmaceuticals

Completed

A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients

Liver Cirrhosis

Spain
Otsuka Pharmaceutical Co., Ltd.

Completed

A Double-blind, Placebo-controlled Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)

Edema, Cardiac

Japan
Otsuka Beijing Research Institute

Completed

Efficacy and Safety Study of Tolvaptan to Treat Patients With Cardiac Edema

Cardiac Edema

China
Rabin Medical Center

Unknown

Desmopressin for Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Bladder Reconstruction

Nocturnal Enuresis

Israel
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study of OPC-41061 Orally Disintegrating (OD) Tablets Using 2 Different Formulations and 2 Dosing Regimens in Healthy Adult Male Subjects

Healthy Adult Male

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter, Open-label, Dose-finding Trial of OPC-41061 to Investigate Efficacy, Pharmacokinetics, Pharmacodynamics, and Safety in Patients With Carcinomatous Edema (Phase 2)

Carcinomatous Edema

Japan
Ferring Pharmaceuticals

Terminated

Study of Minirin Melt® in Adult Patients With Nocturia

Nocturia

Korea, Republic of
Sunnybrook Health Sciences Centre
Sunnybrook Research Institute

Unknown

Safety and Tolerability Analysis of Combining Desmopressin With Docetaxel for the Treatment of Castration-Resistant Prostate Cancer

Castrate Resistance Prostate Cancer
The University of Texas Health Science Center at...

Terminated

Low Dose Vasopressin in Traumatic Shock

Injuries | Shock, Traumatic

United States
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center; Cedars-Sinai Medical Center; North Shore...

Completed

Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial

Blood Loss, Surgical

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (TEMPO 2:4)

Polycystic Kidney, Autosomal Dominant

United States
Duke University

Completed

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure (TACTICS-HF)

Heart Failure | Dyspnea

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Germany, United Kingdom, Spain, Sweden, Hungary, Czech Republic, Denmark
University of Washington

Completed

Study of the Safety and Efficacy of Conivaptan (Vaprisol®) to Raise Serum Sodium Levels in Patients With Severe Traumatic Brain Injury

Severe Traumatic Brain Injury

United States
Sanofi

Completed

Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT).

Chronic Heart Failure

Canada, United States, United Kingdom
Sohag University

Not yet recruiting

Value of Von Willebrand Factor and Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital

Febrile Seizure

Egypt
University Hospital, Tours

Recruiting

Copeptin Kinetics in Critically Ill Patients With Posterior Reversible Encephalopathy Syndrome (XPRESSE)

Posterior Reversible Encephalopathy Syndrome

France
Otsuka Pharmaceutical Development & Commercialization...

Recruiting

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Autosomal Recessive Polycystic Kidney Disease (ARPKD)

United States, Belgium, Spain, Germany, United Kingdom, Poland
Seoul National University Hospital
CHA University

Completed

Comparison of Concentration of Vasopressin During Robot-assisted Laparoscopic Myomectomy (VALENTINE)

Uterine Leiomyoma

Korea, Republic of
University of Chicago

Completed

Postoperative Tolvaptan Use in Left Ventricular Assist Device Implantation Patients (TOLVAD)

Heart Failure | Heart Assist Device | Hyponatremic

United States
Caleb Nelson
Otsuka America Pharmaceutical

Completed

TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study (TCUPS)

Cystinuria

United States
Brigham and Women's Hospital
Otsuka Pharmaceutical Co., Ltd.

Completed

The Role of Vasopressin Antagonism on Renal Sodium Handling

Healthy

Search clinical trials for: Antidiabetic

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