Example: Heart Attack

Search clinical trials for: Antineoplastic Agents, Alkylating

Total 5133 results

NCT04469530

Not yet recruiting

Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

Conditions: Solid Tumor
NCT04467346

Not yet recruiting

Bioequivalence Study Between Temozolomide Oral Suspension (Ped-TMZ) and Temodal® Capsules

Conditions: Therapeutic Equivalency
NCT04466475

Not yet recruiting

Radioimmunotherapy (211At-OKT10-B10) and Chemotherapy (Melphalan) Before Stem Cell Transplantation for the Treatment of Multiple Myeloma

Conditions: CD38 Positive; Plasma Cell Myeloma
NCT04462965

Recruiting

Postoperative Adjuvant Treatment of Completely Resected Mucosal Melanoma Phase II Study

Conditions: Mucosal Melanoma
NCT04457284

Not yet recruiting

Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancer

Conditions: Colorectal Adenocarcinoma
NCT04455139

Not yet recruiting

A Prospective International Multicenter Clinical Trial for Eyes With Relapsed Retinoblastoma

Conditions: Eye Cancer, Retinoblastoma
NCT04451200

Not yet recruiting

SEQUENTIAL AND PERSONALIZED BUSULFAN ADMINISTRATION BY PHARMACOKINETICS PATIENTS WITH MALIGNANT HEMOPATHIA

Conditions: Acute Leukemia; Mielodysplasic Syndrome; Myeloproliferative Neoplasm
NCT04450160

Not yet recruiting

Trial of AEO in New Glioblastoma (GBM)

Conditions: Glioblastoma Multiforme
NCT04443010

Not yet recruiting

Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma

Conditions: Glioblastoma
NCT04443348

Not yet recruiting

Pre-op Pembro + Radiation Therapy in Breast Cancer

Conditions: Triple Negative Breast Cancer; Hormone Receptor Positive (HR+), HER2-negative Breast Cancer; Biopsy-proven, Positive Lymph Node(s)
NCT04440267

Not yet recruiting

Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage

Conditions: Acute Leukemia of Ambiguous Lineage
NCT04440436

Recruiting

Assessment of Safety and Efficacy of IM19 for Recurrent or Refractory (R/R) Non-Hodgkin's Lymphoma(NHL) Patients

Conditions: NHL
NCT04437160

Recruiting

Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy

Conditions: Triple Negative Breast Cancer
NCT04434482

Not yet recruiting

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

Conditions: Advanced Solid Tumours; Small Cell Lung Cancer
NCT04432506

Not yet recruiting

Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma

Conditions: Hematopoietic and Lymphoid Cell Neoplasm; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory High Grade B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
NCT04432714

Recruiting

Lenalidomide in Combination With R-DA-EPOCH in Patients With Untreated DLBCL With MYC Rearrangement

Conditions: DLBCL; Untreated; MYC Gene Rearrangement
NCT04433156

Recruiting

VR-CAP in the First-line Treatment for Patients With Marginal Zone Lymphoma

Conditions: Marginal Zone Lymphoma
NCT04430036

Not yet recruiting

AGEN1884 Plus AGEN2034 Combined With Cisplatin-Gemcitabine for Muscle-Invasive Bladder Cancer

Conditions: Urinary Bladder Neoplasms
NCT04424602

Not yet recruiting

Comparison between2 Drugs in Lupus Nephritis

Conditions: Lupus Nephritis
NCT04425070

Not yet recruiting

A Study of Evaluating the Safety and Efficacy of ATG-010 Combined With Chemotherapy Sequential With ATG-010 Monotherapy Maintenance in Peripheral T- and NK/T-cell Lymphoma

Conditions: Peripheral T-cell Lymphoma; NK/T-cell Lymphoma
NCT04426669

Recruiting

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

Conditions: Gastrointestinal Epithelial Cancer; Gastrointestinal Neoplasms; Cancer of Gastrointestinal Tract; Cancer, Gastrointestinal; Gastrointestinal Cancer; Colo-rectal Cancer; Pancreatic Cancer; Gall Bladder Cancer; Colon Cancer; Esophageal Cancer; Stomach Cancer
NCT04421378

Recruiting

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Conditions: Glioblastoma Multiforme
NCT04423926

Recruiting

Lenalidomide in Combination With CHOP in Patients With Untreated PTCL

Conditions: PTCL, NOS; AITL; ALK- ALCL; Phase III-IV ALK+ ALCL; EATL
NCT04418154

Recruiting

Neoadjuvant Dose-dense EC Followed by ABX With PD-1 for Triple Negative Breast Cancer Patients

Conditions: Triple Negative Breast Cancer
NCT04418219

Not yet recruiting

A Breast Cancer Vaccine (SV-BR-1-GM) in Combination With Pembrolizumab for the Treatment of Persistent, Recurrent, or Metastatic Breast Cancer

Conditions: Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Breast Carcinoma; Prognostic Stage IV Breast Cancer AJCC v8; Recurrent Breast Carcinoma; Refractory Breast Carcinoma
NCT04416984

Recruiting

Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma (ALPHA-2)

Conditions: Relapsed/Refractory Large B Cell Lymphoma
NCT04412707

Recruiting

A PK, Safety and Tolerability Study of Peripheral and Central Infusion of Melflufen in RRMM Patients

Conditions: RRMM
NCT04402073

Not yet recruiting

Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma

Conditions: Medulloblastoma
NCT04400045

Recruiting

Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome

Conditions: Nijmegen Breakage Syndrome
NCT04400188

Recruiting

A Study of Fluzoparib (SHR-3162) and Temozolomide With or Without SHR-1316 in Treating Patients With Replapsed Small Cell Lung Cancer

Conditions: Small Cell Lung Cancer
NCT04396860

Not yet recruiting

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Conditions: Gliosarcoma; MGMT-Unmethylated Glioblastoma
NCT04397679

Not yet recruiting

Partial Brain Radiation Therapy, Temozolomide, Chloroquine, and Tumor Treating Fields Therapy for the Treatment of Newly Diagnosed Glioblastoma

Conditions: Glioblastoma; Gliosarcoma
NCT04397770

Not yet recruiting

Camrelizumab Plus Apatinib and Temozolomide as First Line Therapy in Advanced Acral Melanoma

Conditions: Melanoma
NCT04394858

Not yet recruiting

Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer

Conditions: Advanced Adrenal Gland Pheochromocytoma; Advanced Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Paraganglioma; Unresectable Adrenal Gland Pheochromocytoma; Unresectable Paraganglioma
NCT04395222

Not yet recruiting

Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation

Conditions: Hematologic Malignancy; Bone Marrow Transplant
NCT04392648

Withdrawn

A Study to Evaluate the Safety, Tolerability and Efficacy of Intravenous TAK-573 as Part of Combination Therapy in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Conditions: Relapsed and/or Refractory Multiple Myeloma
NCT04394728

Completed

Pharmacometabolomic of Trabectedin in Soft Tissue Patients

Conditions: Sarcoma
NCT04392037

Not yet recruiting

Iberdomide Combined With Low-dose Cyclophosphamide and Dexamethasone

Conditions: Multiple Myeloma
NCT04389229

Not yet recruiting

OVSTAR TIL Trial (OVarian Cancer Co-STimulatory Antigen Receptor TIL Trial)

Conditions: Ovarian Cancer Metastatic
NCT04390399

Recruiting

Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for First and Second Line Treatment of Locally Advanced or Metastatic Pancreatic Cancer

Conditions: Pancreatic Cancer
NCT04388033

Recruiting

Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients.

Conditions: Glioblastoma; Glioma; Neoplasms, Neuroepithelial; Neuroectodermal Tumors; Neoplasms; Neoplasms, Nerve Tissue; Vaccines; Immunologic Factors
NCT04388475

Recruiting

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Conditions: Recurrent Malignant Glioma; Brain Glioblastoma
NCT04388839

Not yet recruiting

Evolutionary Therapy for Rhabdomyosarcoma

Conditions: Rhabdomyosarcoma
NCT04383119

Not yet recruiting

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma

Conditions: Leiomyosarcoma of Ovary; Soft Tissue Sarcoma
NCT04384692

Not yet recruiting

Ruxolitinib for the Treatment of Graft Versus Host Disease Following Stem Cell Transplant in Patients With Primary and Secondary Myelofibrosis

Conditions: Primary Myelofibrosis; Secondary Myelofibrosis
NCT04385173

Recruiting

Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma

Conditions: Recurrent Glioblastoma; Refractory Glioblastoma
NCT04385277

Not yet recruiting

Treatment With Dinutuximab in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma

Conditions: Ganglioneuroblastoma, Nodular; High-Risk Neuroblastoma
NCT04380376

Recruiting

Low-doses Melphalan Inhalation in Patients With COVID-19 (CoronavIrus Disease 2019) Pneumonia

Conditions: COVID-19; Viral Pneumonia
NCT04380831

Recruiting

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

Conditions: Systemic Scleroderma
NCT04377932

Not yet recruiting

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Conditions: Liver Cancer; Rhabdomyosarcoma; Malignant Rhabdoid Tumor; Liposarcoma; Wilms Tumor; Yolk Sac Tumor