Search clinical trials for: Antithrombin-III

Total 10415 results

Policlinico Hospital
The Mediterranean Institute for Transplantation and Advanced Specialized...

Completed

Antithrombin Supplementation in ECMO

Extracorporeal Membrane Oxygenation

Italy
Seoul National University Hospital

Completed

Antithrombin III Concentrate After Liver Transplantation

Liver Transplant; Complications

Korea, Republic of
University of Bari

Unknown

Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery (ATIII)

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Acute Coronary Syndrome | Mitral Valve Stenosis

Italy
SK Chemicals Co., Ltd.
Korea University Anam Hospital

Completed

Phase1 Syudy to Evaluate the Safety and PK/PD of Human Antithrombin III

Healthy

Korea, Republic of
Seoul National University Hospital

Active, not recruiting

Antithrombin-III for Patients With Hepatic Veno-occlusive Diseases Following Hematopoietic Stem Cell Transplantation

Hepatic Veno-Occlusive Disease

Korea, Republic of
Grifols Therapeutics LLC
Covance; Clinipace Worldwide

Completed

Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary Bypass

Cardiac Surgery | Cardiopulmonary Bypass

United States
Kyowa Kirin Co., Ltd.

Completed

An Open-label Study of KW-3357 (3357-004)

Disseminated Intravascular Coagulation (DIC)

Japan
Medical College of Wisconsin
Children's National Research Institute; rEVO Biologics

Terminated

Antithrombin III Supplementation for Cardiopulmonary Bypass in Neonates

Postoperative Hemorrhage

United States
Children's Hospital Los Angeles

Withdrawn

Pharmacokinetic Study of Recombinant AT III in Neonates Undergoing ECMO

Neonates on ECMO

United States
Kyowa Kirin Co., Ltd.
Japan Blood Products Organization

Completed

KW-3357 Study in Patients With Early Onset Severe Preeclampsia

Preeclampsia

Japan
rEVO Biologics

Completed

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (PRESERVE-1)

Preeclampsia

United States
Enrique Ginzburg
Grifols Biologicals, LLC

Terminated

Antithrombin III in Infectious Disease Caused by COVID-19

Covid19 | Antithrombin III Deficiency

United States
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
Maimónides Biomedical Research Institute of Córdoba

Completed

Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19

Severe Acute Respiratory Syndrome | Covid19 | Distress Respiratory Syndrome

Spain
Mayo Clinic
rEVO Biologics

Terminated

Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac Surgery

Thrombophilia Due to Acquired Antithrombin III Deficiency

United States
rEVO Biologics

Completed

Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery

Antithrombin III Deficiency

United States, France, United Kingdom, Germany, Canada, Austria, Australia, Italy
Duke University
Grifols Biologicals, LLC

Completed

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

ATIII Deficiency

United States
Octapharma

Recruiting

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

Congenital Antithrombin Deficiency

Spain, Italy, United States, Serbia, France, Hungary, Austria, Germany, United Kingdom, Israel
Dr. Siyami Ersek Thoracic and Cardiovascular Surgery...

Completed

Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO

Extracorporeal Membrane Oxygenation Complication | Antithrombin III Deficiency

Turkey
Children's Hospital Medical Center, Cincinnati
Grifols Biologicals, LLC

Completed

Evaluation Of The Pharmacokinetics Of Antithrombin III In Neonates And Infants Undergoing CPB And ECMO Support

Cardiopulmonary Bypass | Extracorporeal Membrane Oxygenation Complication

United States
LEO Pharma

Terminated

Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe Sepsis

Disseminated Intravascular Coagulation
Asan Medical Center

Completed

Antithrombin III and Post-liver Transplantation Acute Kidney Injury

Liver Transplantation and Antithrombin

Korea, Republic of
rEVO Biologics

Completed

Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations. (rhAT)

Antithrombin Deficiency, Congenital

France, United Kingdom, Germany, United States, Sweden, Italy
Assiut University

Unknown

Haemostatic Imbalance in Patients With Chronic Liver Disease

Haemostasis Imbalance in Chronic Liver Disease
Vastra Gotaland Region
Octapharma

Withdrawn

Atenativ Effect on Uterine Blood Flow and Preeclampsia

Antithrombin III Deficiency

Sweden
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia (ATLAS-NEO)

Hemophilia

Greece, Korea, Republic of, France, Taiwan, Italy, Spain, United States, Canada, China, Germany, India, Japan, Mexico, South Africa, Turkey, Poland
Jonathan Stine
Grifols Therapeutics LLC

Withdrawn

Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis (PiVoT)

Cirrhosis, Liver | Portal Vein Thrombosis

United States
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

Hemophilia A

Taiwan
The Hospital for Sick Children

Completed

Antithrombin Enhancement May Improve Anticoagulation Efficiency in Infants Undergoing Cardiopulmonary Bypass for Cardiac Surgery

Cardiopulmonary Bypass

Canada
Octapharma

Completed

Observational, Retrospective Study to Evaluate Coagulation Changes and the Influence of Antithrombin III Treatment in Patients With Severe COVID-19 Infection

Covid19

Austria, France, Germany, Sweden
Instituto Grifols, S.A.

Completed

Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass

Coronary Artery Bypass | Acquired Antithrombin III Deficiency

Italy
Karadeniz Technical University

Completed

Raloxifene on Coagulation System in the Postmenopausal Women

Postmenopausal Women | Raloxifene
University of Rochester

Terminated

Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)

Congenital Heart Disease

United States
Biotronik SE & Co. KG

Completed

Master Study of the BIOMONITOR III and Incision and Insertion Tool (FIT OneStep)

Syncope | Atrial Fibrillation (AF) | Cryptogenic Stroke | Tachyarrhythmia

Spain, Australia, Germany, Switzerland, Austria, Denmark
Children's Hospital of Philadelphia
University of Pennsylvania

Completed

Differences Between the Bayley-II and the Bayley-III in Very Preterm Infants at 2 Years

Infant Development

United States
University of Minho

Completed

A Study Protocol for an Online Intervention to Promote School Engagement

Cerebral Palsy

Portugal
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Nektar Therapeutics

Recruiting

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Non-Hodgkin Lymphoma | Relapsed/Refractory Diffuse Large B-cell Lymphoma

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)

Reperfusion Injury

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) (CAPITL)

Reperfusion Injury

Belgium
Sun Pharmaceutical Industries Limited

Terminated

To Evaluate The Efficacy And Safety Of Sunpharma1505 Compared With Reference1505 In Subjects With Active Rheumatoid Arthritis

Active Rheumatoid Arthritis

Belgium, Netherlands
Sun Pharmaceutical Industries Limited

Completed

Long-Term Extension Trial of Tildrakizumab to Prove Its Safety in Subjects With Psoriatic Arthritis Who Have Previously Completed Study With Tildrakizumab.

Psoriatic Arthritis

United States, Argentina, Hungary, Mexico, Poland, Russian Federation, Spain, Ukraine
Damanhour University
Tanta University

Completed

Association Between Inflammatory Biomarkers and LV Function in Patients With CVD

Heart Failure | Stable Angina

Egypt
AstraZeneca

Completed

AZD9056 Relative Bioavailability Study

Healthy

United Kingdom
HK inno.N Corporation

Completed

A Pharmacodynamic Study of SLM0807, HKB0701 and CJ30001 in Healthy Subject

Diabetes Mellitus
Sun Pharmaceutical Industries Limited
Moebius Medical Ltd.; Nordic Bioscience Clinical Development (NBCD)

Completed

Efficacy and Safety of MM-II for Treatment of Knee Pain in Subjects With Symptomatic Knee Osteoarthritis

Osteoarthritis of Knee

United States, Denmark, Hong Kong
Regina Elena Cancer Institute
Icahn School of Medicine at Mount Sinai; University of Roma La Sapienza

Unknown

Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis | Relapse

United States, Italy
Sun Pharma Advanced Research Company Limited

Completed

Efficacy and Safety of SPARC1310 in Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Medical University of Vienna

Unknown

Fumaric Acid Ester-PUVA Therapy Versus Acitretin -PUVA Therapy in Pustular Palmoplantar Psoriasis (FVSA-PUVA)

Pustular Palmoplantar Psoriasis

Austria
Centre d'Etudes et de Recherche pour l'Intensification...
University Hospital, Grenoble

Completed

Multicenter Assessment of the PDA-FIT System in Type 1 Diabetic Patients (TELEDIAB-1)

Type 1 Diabetes

France

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