Search clinical trials for: Antitussive Agents

Total 188353 results

Marathon Pharmaceuticals, LLC

Withdrawn

A Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Investigational Product MP-101 in Subjects With Short Bowel Syndrome Who Have Had an Inadequate Response to Anti-Diarrheals

Short Bowel Syndrome | Short Gut Syndrome | SBS | Short Gut | Short Bowel

United States
National Cheng-Kung University Hospital

Unknown

Dextromethorphan and Silymarin in Chronic Kidney Disease (CKD) Patients (CKD)

Proteinuria

Taiwan
University of Oslo
The Research Council of Norway

Completed

Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services

Opiate Addiction

Norway
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of Tiagabine for Cocaine Dependence in Methadone-Maintained Individuals - 1

Cocaine-Related Disorders | Opiate Dependence
Brigham and Women's Hospital
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical Trial

Spinal Cord Injury | Allodynia | Central Neuropathic Pain

United States
Pangaea Global AIDS Foundation
National Institute on Drug Abuse (NIDA); Muhimbili University of Health and...

Unknown

Study of Integrating Antiretroviral Therapy With Methadone Treatment for People Who Inject Drugs (IMAT)

HIV | Opioid Dependence
Yale University
National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs

Completed

Efficacy of Varenicline in Methadone-Stabilized Cocaine Users

Nicotine Dependence | Cocaine Dependence

United States
Washington University School of Medicine

Completed

Methadone in Pediatric Anesthesia

Anesthesia

United States
University of Texas Southwestern Medical Center

Completed

TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management

Postoperative Pain

United States
Friends Research Institute, Inc.

Completed

Reengineering Methadone Treatment Study of Patient-centered Methadone Treatment

Opiate Dependence

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
Baylor College of Medicine

Terminated

Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia

Pain, Postoperative

United States
King Abdullah International Medical Research Center

Unknown

Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients

Pain | Opioid Tolerance | Analgesia Tolerance

Saudi Arabia
Boehringer Ingelheim

Completed

Study to Investigate Safety With Special Emphasis on ECG Effects and Tolerability After Oral Doses of Dextromethorphan Hydrobromide Monohydrate in Healthy Male and Female Subjects

Healthy
Mundipharma Medical Company

Completed

Morphine Slow-release Capsules in Substitution Therapy

Opiate Dependent

Switzerland
National Development and Research Institutes, Inc.
National Institute on Drug Abuse (NIDA); New York City Department of Health... and other collaborators

Completed

Buprenorphine Maintenance for Opioid-Addicted Persons in Jail and Post-Release

Opiate Addiction
Napp Pharmaceuticals Limited

Completed

A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis

Osteoarthritis | Back Pain

United Kingdom
Dr. Casey Stondell, MD
Pacira Pharmaceuticals, Inc

Recruiting

IV Methadone vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction (AIMS)

Adolescent Idiopathic Scoliosis | Juvenile Idiopathic Scoliosis

United States
The University of Texas Health Science Center,...

Not yet recruiting

Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months

Spine Surgery

United States
Elysium Therapeutics, Inc.
National Institute on Drug Abuse (NIDA); Medpace, Inc.; Ohio Third Frontier; Charles...

Recruiting

Evaluate the Safety and Pharmacokinetic Profile of ETR028 and ETR029 in Healthy Adult Subjects

Acute Pain

United States
Beijing Grand Johamu Pharmaceutical Company, Ltd.

Recruiting

A Retrospective, Real-world Study of ELP Used in the Expectorant Treatment of Community-acquired Pneumonia

Community-acquired Pneumonia

China
National Institute on Drug Abuse (NIDA)

Completed

Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management

Cocaine-Related Disorders | Opiate-Related Disorders

United States
Roxane Laboratories
Quintiles, Inc.

Terminated

A Study of Oral Codeine Sulfate in Pediatric Patients With Post-procedural Pain

Pain

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets for Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
United Health Services Hospitals, Inc.
Binghamton University

Recruiting

Evaluating the Pharmacokinetics and Patient Outcomes of Buprenorphine Microdosing

Opioid Use Disorder | Opioid Withdrawal

United States
National Institutes of Health Clinical Center (CC)

Completed

The Effect of Milk Thistle on the Pharmacokinetics of Indinavir

HIV Infection | Healthy

United States
Elizabeth Krans, MD
National Institute on Drug Abuse (NIDA); OpalGenix, Inc

Recruiting

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Pregnancy Related | Opioid Use Disorder

United States
University of Aarhus

Recruiting

Intraoperative Methadone for Postoperative Pain in Patients Undergoing Tonsillectomy (METATONS)

Postoperative Pain

Denmark
University of Sao Paulo General Hospital

Recruiting

Methadone Anesthesia For Kidney Transplant Receptors

Surgery | Renal Failure Chronic

Brazil
OrthoCarolina Research Institute, Inc.

Active, not recruiting

Opioid-Free Orthopaedic Surgery (CORE)

Pain Management

United States
Albert Einstein College of Medicine
National Institute on Drug Abuse (NIDA); Montefiore Medical Center; Fordham University

Completed

Neurocognitive Effects of Opiate Agonist Treatment (NEO)

HIV Infections | HIV | Opioid-Related Disorders

United States
John van den Anker

Completed

The Use of Methadone in Newborn Infants (Methadone)

Premature Birth of Newborn | Critically Ill

United States
Mayo Clinic

Terminated

Methadone Versus Morphine for Cancer-Related Pain

Neoplasms | Pain

United States
Tan Tock Seng Hospital

Completed

Comparison of the Efficacy of Oral Oxycodone and Oral Codeine in the Treatment of Postcraniotomy Pain

Postcraniotomy Pain

Singapore
London Health Sciences Centre

Completed

Proparacaine vs Placebo for Corneal Injuries (Dogma)

Corneal Abrasions

Canada
Moleac Pte Ltd.
Moleac Australia Pty Ltd

Completed

Drug-Drug Interaction Study of MLC1501 Using Cocktail of Drugs Acting as Sensitive Clinical Probes/Substrates of Cytochrome P450 Isoenzymes and Transporters in Healthy Subjects

Stroke

Australia
Sun Pharma Advanced Research Company Limited

Completed

Bioavailability Study of SPARC001 in Healthy Adult Volunteers

Healthy
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Dextromethorphan

United States
Centre for Addiction and Mental Health
Academic Health Science Centres

Completed

Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation

Constipation

Canada
University Hospital, Caen

Completed

CYTRAM (Cytochrome P450, Tramadol) (CYTRAM)

Post-operative Patients Treated by Tramadol

France
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Clinical Trial of Topiramate for Cocaine Addiction

Cocaine Dependence

United States
Maimónides Biomedical Research Institute of Córdoba

Recruiting

Prevention and Treatment With Hydroxychloroquine + Azithromycin of Acute Respiratory Syndrome Induced by COVID-19 (AMBUCOV)

Covid19 | Acute Respiratory Distress Syndrome

Spain
Asbjørn Mohr Drewes
Aarhus University Hospital

Completed

Opium Tincture Against Chronic Diarrhea - Patients

Chronic Diarrhea

Denmark
Asbjørn Mohr Drewes

Completed

Opium Tincture Against Chronic Diarrhea - Healthy

Chronic Diarrhea

Denmark
Galera Therapeutics, Inc.

Completed

Study to Evaluate the Effects of 90 mg Intravenous Infusions of GC4419 on the Single Dose Pharmacokinetics of Dextromethorphan in Healthy Adult Subjects

Healthy

United States
University Hospital Hradec Kralove
Masaryk University

Recruiting

The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases (INFURO)

Dyspnea

Czechia
Rutgers, The State University of New Jersey
National Institute on Drug Abuse (NIDA); University of Utah

Recruiting

Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement

Tobacco Use | Opioid Use | Polysubstance Abuse

United States
Medical College of Wisconsin

Completed

Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients

Pain | Scoliosis

United States
Andrew Waberski

Terminated

Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery (CV_RCT_M_F)

Opioid Use, Unspecified

United States
simon.haroutounian

Completed

Epidural Methadone in Healthy Volunteers

Pain, Acute

United States

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