Search clinical trials for: Artefenomel-Ferroquine

Total 25 results

Sanofi
Medicines for Malaria Venture

Completed

Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Uganda
Sanofi
Medicines for Malaria Venture

Terminated

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FALCI)

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Mozambique, Uganda, Vietnam
Centre de Recherche Médicale de Lambaréné

Completed

Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection (SACT)

Schistosomiasis Haematobia

Gabon
Medicines for Malaria Venture

Completed

Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.

Uncomplicated Plasmodium Falciparum Malaria

Uganda, Benin, Burkina Faso, Congo, The Democratic Republic of the, Gabon, Mozambique, Vietnam
Sanofi

Completed

A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria

Malaria

Gabon, Kenya
Zydus Lifesciences Limited

Not yet recruiting

A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carriers

Asymptomatic Condition | Falciparum Malaria | Uncomplicated Malaria
Sanofi

Terminated

Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FARM)

Plasmodium Falciparum Infection

Benin, Burkina Faso, Cameroon, Gabon, Kenya, Tanzania
Medicines for Malaria Venture
Queensland Institute of Medical Research

Completed

Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265 (OZ/DSMCombo)

Malaria

Australia
Medicines for Malaria Venture

Completed

A Dose-escalation Study to Investigate Safety and Toleration of OZ439

Malaria

United Kingdom
Medicines for Malaria Venture

Completed

OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation

Malaria

Thailand
Medicines for Malaria Venture
Mahidol University

Completed

Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection

Malaria, Falciparum | Malaria, Vivax
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; Queensland Institute...

Terminated

A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection (DSMOZ-2)

Malaria

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer... and other collaborators

Completed

Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent (OZGAM)

Malaria

Australia
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State

Malaria

United Kingdom
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers

Malaria

United Kingdom
Medicines for Malaria Venture

Completed

A Comparison of the Bioavailability of OZ439 When Delivered Directly to the Small Intestine, or Via the Oral Route

Healthy Volunteers

United Kingdom
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets

Malaria

United Kingdom
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Malaria

United Kingdom
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP

Malaria

Australia
Medicines for Malaria Venture
Cross Research S.A.

Completed

Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy Subjects

Healthy

Switzerland
Medicines for Malaria Venture

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects

Healthy Volunteers | Malaria Falciparum | Malaria Vivax

United States
Medicines for Malaria Venture
Syneos Health; Nucleus Network Ltd

Completed

Study To Investigate The Relative Bioavailability of OZ439 Formulations In Healthy Volunteers

Healthy Volunteers

Australia
Medicines for Malaria Venture

Completed

Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study

Malaria

Netherlands

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