Search clinical trials for: BIBR 277

Total 1019 results

AbbVie

Completed

A Study to Evaluate the Safety and Antiviral Effect of Multiple Doses of ABT-493 and ABT-530 in Adults With Genotype 1 Hepatitis C Virus (HCV)

Chronic Hepatitis C | Hepatitis C Virus | Compensated Cirrhosis
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age

Respiratory Syncytial Virus (RSV)

United States
Novo Nordisk A/S

Completed

A Research Study of How Different Amounts of a New Medicine NNC0148-0287 C (Insulin 287) Works on the Blood Sugar of People Who Are Japanese With Type 1 Diabetes When Given Once a Week

Diabetes Mellitus, Type 1

Japan
Lund University Hospital

Active, not recruiting

Systemic Targeted Adaptive RadioTherapy of NeuroEndocrine Tumors. (START-NET)

Neuroendocrine Tumors

Sweden
Oncorus, Inc.
Merck Sharp & Dohme LLC

Terminated

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Melanoma | Cancer | Breast Cancer | Solid Tumor | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Advanced Solid Tumor | Liver Metastases | Colorectal Carcinoma | Non-melanoma Skin Cancer

United States, Canada
Sue O'Dorisio
Advanced Accelerator Applications

Withdrawn

Dosimetry Guided PRRT With 177Lu-DOTATATE in Children and Adolescents

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma

United States
Aduro Biotech, Inc.
Incyte Corporation

Terminated

Safety and Efficacy of CRS-207 With Epacadostat in Platinum Resistant Ovarian, Fallopian or Peritoneal Cancer (SEASCAPE)

Platinum-resistant Ovarian Cancer | Platinum-resistant Fallopian Cancer | Platinum-resistant Peritoneal Cancer

United States, Canada
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors

Advanced Malignant Solid Tumors

Japan
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Not yet recruiting

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization ((SEEtoTREAT))

Prostate Cancer | Advanced Cancer
Takeda

Not yet recruiting

A Study of Recombinant Von Willebrand Factor (rVWF) (TAK-577) in Children With Severe Von Willebrand Disease (vWD)

Von Willebrand Disease (VWD)
Advanced Accelerator Applications

Active, not recruiting

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

Pheochromocytoma | Paraganglioma | Gastroenteropancreatic Neuroendocrine Tumors

United States, Spain, France, Poland, United Kingdom
Novo Nordisk A/S

Completed

A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0148-0000-0287 in Healthy Subjects

Diabetes Mellitus, Type 2 | Diabetes

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...

Terminated

Quantification of Contrast Enhanced Ultrasound (CEUS) in the Detection of Prostate Cancer (AMC_2011_190)

Prostate Cancer

Netherlands
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study in Health Adult Volunteers

Healthy

United States
Memorial Sloan Kettering Cancer Center
Boehringer Ingelheim

Completed

Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis

Lung Cancer | Lung Metastases

United States
National Cancer Institute (NCI)

Recruiting

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Neuroendocrine Neoplasms

United States
CTI BioPharma
Chroma Therapeutics

Completed

Crossover Trial of the Effect of a High-Fat Meal on the PK of Oral CHR 2797 in Healthy Male Subjects (8265134)

Healthy

United States
Seres Therapeutics, Inc.

Completed

A Study to Evaluate the Safety, Tolerability and Microbiome Dynamics of SER-287 in Subjects With Mild-to-Moderate Ulcerative Colitis

Ulcerative Colitis

United States
Abbott
Abbott Japan Co.,Ltd

Completed

Dose-response Study of Paricalcitol Injection in Chronic Kidney Disease Patients Receiving Hemodialysis

Secondary Hyperparathyroidism | Chronic Kidney Disease on Hemodialysis

Japan
Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) vs Gemcitabine-cisplatin in 1st Line Non-small Cell Lung Cancer (NSCLC)

Adenocarcinoma | Carcinoma, Non-Small-Cell Lung

China, Korea, Republic of, Thailand
Boehringer Ingelheim

Completed

BIBW 2992 and Letrozole in Hormonoresistant Metastatic Breast Cancer

Breast Neoplasms

France
Changhai Hospital

Recruiting

Oral Helicobacter Pylori Eradication

H. Pylori Infection

China
Jules Bordet Institute

Completed

177Lutetium-octreotate Treatment Prediction Using Multimodality Imaging in Refractory NETs (LUMEN)

Gastroenteropancreatic Neuroendocrine Tumors

Belgium
Organon and Co

Completed

A Study Comparing Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Patients at Risk for Heart Disease (0653-023)(COMPLETED)

Coronary Disease
Massachusetts General Hospital
AstraZeneca; Astex Pharmaceuticals, Inc.

Active, not recruiting

Oral Decitabine (ASTX727) and Durvalumab in Recurrent and/or Metastatic Head and Neck Cancer Patients

Head and Neck Cancer

United States
Syndax Pharmaceuticals

Terminated

A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib

Non Small Cell Lung Cancer

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Breast Cancer | Advanced Malignant Solid Tumors

United States, Taiwan, United Kingdom, Hong Kong, Belgium, France, Spain, China, Netherlands, Poland, Sweden
University of Miami

Completed

Photodynamic Therapy With Porfimer Sodium in Treating Patients With Precancerous Lesions, Cancer, or Other Disease of the Aerodigestive Tract

Head and Neck Cancer | Precancerous/Nonmalignant Condition

United States
Chroma Therapeutics

Terminated

Clinical Trial of the Safety and Effectiveness of CHR-2797 With Erlotinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Peking University

Not yet recruiting

Phase II Study to Evaluate the Efficacy and Safety of 177Lu-Dotatate in the First-line Treatment of Patients With Locally Advanced or Metastatic, Somatostatin Receptor-positive G2 or G3 Gastroenteropancreatic Neuroendocrine Tumors

Neuroendocrine Tumors

China
John O. Prior

Not yet recruiting

Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approach (ThernSarc)

Soft Tissue Sarcoma
University Hospital, Basel, Switzerland
Swiss National Science Foundation; Paul Scherrer Institute (PSI)

Recruiting

Combined Beta- Plus Auger Electron Therapy Using a Novel Somatostatin Receptor Subtype 2 Antagonist Labelled With Terbium-161 (161Tb-DOTA-LM3) (Beta plus)

Neuroendocrine Neoplasia's (NENs) | Gastroenteropancreatic Neuroendocrine Tumour (GEP-NET)

Switzerland
Washington University School of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C

Niemann-Pick Disease, Type C

United States
Novo Nordisk A/S

Completed

A Research Study in People With Type 2 Diabetes to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine

Diabetes Mellitus, Type 2

United States, Italy, Canada, Germany, Czechia
Hoffmann-La Roche

Terminated

A Study of Ocrelizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Belgium, United Kingdom, Canada, New Zealand, Spain, Russian Federation, Australia, Netherlands
National Cancer Institute (NCI)

Completed

Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma

Recurrent Melanoma | Stage IV Melanoma

United States
Boehringer Ingelheim

Completed

Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or Gefitinib

Carcinoma, Non-Small-Cell Lung

Spain
University of Leeds

Completed

Feasibility of Consumption of Nutritional Supplementation in Primary Ciliary Dyskinesia ((PCD))

Primary Ciliary Dyskinesia

United Kingdom
AbbVie

Completed

A Study to Evaluate Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir in Treatment-Naïve Hepatitis C Virus Genotype 1b-Infected Adults (GARNET)

Hepatitis C Virus | Hepatitis C Infection
Weill Medical College of Cornell University
Merck Sharp & Dohme LLC; Novartis; GI Research Foundation

Recruiting

Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer (iPRRT)

Merkel Cell Carcinoma

United States
Johannes Gutenberg University Mainz

Terminated

BIBW 2992 as add-on to Gem/Cis in Advanced Biliary Tract Cancer

Metastatic Disease

Germany
Fundación de investigación HM
Syntax for Science, S.L

Recruiting

A Clinical Study to Assess the Combination of Two Drugs (177Lu-DOTATATE and Nivolumab) in Neuroendocrine Tumours

Neuroendocrine Tumours (NET) | Neuroendocrine Carcinomas (NEC)

Spain
Hoffmann-La Roche

Completed

A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

Canada, United States
University of Virginia
Syndax Pharmaceuticals

Completed

A Pilot Study of the Combination of Entinostat With Capecitabine in High Risk Breast Cancer After Neo-adjuvant Therapy (Breast49)

Breast Cancer | Metastatic Breast Cancer

United States
Unity Health Toronto

Completed

Satiety Study of a Carbohydrate Meal to a Highly Viscous Gel Meal (InGel)

Obesity

Canada
Hospices Civils de Lyon

Recruiting

External Validation of Clinical Prediction Tools for Estimating Salt and Potassium Intake in Nephrology Patients. (UniverSel)

Chronic Kidney Diseases

France
Columbia University

Recruiting

Opioid Dispensing Device for Post-Operative Pain in Cancer Patients Patients

Breast Cancer | Opioid Use

United States
National Cancer Institute (NCI)

Completed

Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma

Melanoma | Neoplasm Metastasis

United States
Boehringer Ingelheim

Completed

BIBF 1120 Versus Bevacizumab in Metastatic Colorectal Cancer

Colorectal Neoplasms

Belgium, France, Germany, Italy, Spain
Vastra Gotaland Region
Advanced Accelerator Applications

Active, not recruiting

177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours (LuPARP)

Thymoma | Neuroendocrine Tumors | Mesothelioma | Clinical Trial, Phase I

Sweden

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