Search clinical trials for: BIBR 796 BS

Total 733 results

Boehringer Ingelheim

Completed

A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma Patients

Carcinoma, Hepatocellular

Korea, Republic of, Taiwan
AstraZeneca
Parexel

Completed

A Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD7594 Administered Once Daily by Inhalation in Asthmatic Subjects

Asthma

United States, Germany, South Africa, Ukraine, Japan, Hungary, Poland, Bulgaria
Jun Tao

Recruiting

Effect of Berberine Hydrochloride on Blood Pressure and Vascular Endothelial Function in Patients With Hypertension

Hypertension | Blood Pressure | Endothelial Dysfunction

China
Yamo Pharmaceuticals LLC

Completed

Safety of L1-79 in Autism

Autism

United States
Temple University
Boehringer Ingelheim

Terminated

Continuation of Nintedanib After Single Lung Transplantation in IPF Subjects

Idiopathic Pulmonary Fibrosis | Lung Transplant; Complications

United States
Boehringer Ingelheim

Completed

BIBW 2992 Administered as Tablet (Final Formulation) Compared to BIBW 2992 Drinking Solution and BIBW 2992 Tablet (Trial Formulation II) in Healthy Male Volunteers

Healthy
Merck Sharp & Dohme LLC

Completed

A Phase 3 Study Comparing Dinaciclib Versus Ofatumumab in Patients With Refractory Chronic Lymphocytic Leukemia (P07714)

Chronic Lymphocytic Leukemia (CLL)
AbbVie

Recruiting

Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States, Korea, Republic of, Israel, Japan, Australia, Spain
Martin-Luther-Universität Halle-Wittenberg
GALMED GmbH

Completed

TRICC-C (AIO-KRK-0111): BIBF 1120 Versus Placebo in Patients Receiving Oxaliplatin Plus Fluorouracil and Leucovorin (mFOLFOX6) for Advanced, Chemorefractory Metastatic Colorectal Cancer (mCRC) (AIO-KRK-0111)

Colorectal Cancer

Germany
Acerta Pharma BV

Active, not recruiting

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL)

Belgium, France, United Kingdom, United States, Italy, Poland, Netherlands, Australia, Czechia, Spain
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Autoimmune Hemolytic Anemia | Warm Antibody Autoimmune Hemolytic Anemia | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

United States
M.D. Anderson Cancer Center
Boehringer Ingelheim

Terminated

Nintedanib For HER2-Negative Metastatic Inflammatory Breast Cancer (MIBC)

Breast Cancer

United States
Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) in Head & Neck Cancer

Head and Neck Neoplasms | Carcinoma, Squamous Cell

United States, Belgium, France, Spain
Boehringer Ingelheim

Completed

Safety and Tolerability of 4 Different Dosage Strengths of BIBW 2992 Tablets to Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 BS and Metformin After Co-administration Compared to the Bioavailability of BI 1356 BS Alone and Metformin Alone in Healthy Male Volunteers

Healthy
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Negative Symptoms of Schizophrenia

Schizophrenia

United States, Bulgaria, Hungary, Poland, Puerto Rico
Boehringer Ingelheim

Completed

LUX-Lung 5: Afatinib Plus Weekly Paclitaxel Versus Investigator's Choice of Single Agent Chemotherapy Following Afatinib Monotherapy in Non-small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib

Carcinoma, Non-Small-Cell Lung

Austria, Germany, Spain, China, Taiwan, Argentina, Australia, Belgium, Brazil, Finland, France, Hungary, India, Israel, Italy, Korea, Republic of, Mexico, Netherlands, Peru, Poland, Russian Federation, Ukraine, United Kingdom
Boehringer Ingelheim

Completed

A Study of BIBW 2992 (Afatinib) in Patients With Metastatic Colorectal Cancer

Colorectal Neoplasms

United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Intermittent Explosive Disorder

Intermittent Explosive Disorder

United States
Sangart

Completed

Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty

Ischemia | Hypotension

Netherlands, Belgium, Czech Republic, Sweden, Poland, United Kingdom
Ann & Robert H Lurie Children's Hospital of Chicago
Northwestern University

Terminated

Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine

Glioblastoma Multiforme | Ependymoma | Anaplastic Ependymoma | Astrocytoma, Grade III | Clear Cell Ependymoma

United States
Otsuka Pharmaceutical Development & Commercialization...

Recruiting

Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Agitation in Patients With Dementia of the Alzheimer's Type

United States, Belgium, Canada, Chile, Colombia, Croatia, Hungary, Mexico, Netherlands, Slovakia, Slovenia, Spain, Ireland
Otsuka Pharmaceutical Development & Commercialization...

Recruiting

Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Agitation in Patients With Dementia of the Alzheimer's Type

United States, Bulgaria, Denmark, Estonia, Greece, Poland, Portugal, Puerto Rico, United Kingdom, Germany, Ukraine
Otsuka Pharmaceutical Development & Commercialization...

Completed

Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Agitation in Patients With Dementia of the Alzheimer's Type

Spain, United States, Italy, United Kingdom, Hungary, France, Poland, Australia, Bulgaria, Czechia, South Africa
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1356 BS in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2
National Taiwan University Hospital

Recruiting

Primary Tumor Resection With EGFR TKI for Stage IV NSCLC

NSCLC Stage IV

Taiwan
Boehringer Ingelheim

Completed

Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)

Colorectal Neoplasms

United States, Argentina, Australia, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Hong Kong, Israel, Italy, Japan, Korea, Republic of, Mexico, Netherlands, Poland, Portugal, Russian Federation, Spain, Sweden, Taiwan, T... and more
Boehringer Ingelheim

Completed

Trial of BIBW 2992 (Afatinib) + Cetuximab in Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Netherlands
Centro Nacional de Investigaciones Oncologicas...
M.D. Anderson Cancer Center; Hospital Universitari de Bellvitge; Grupo Espanol... and other collaborators

Completed

Neoadjuvant Paclitaxel Versus BIBF 1120 Priming Followed by BIBF 1120 Plus Paclitaxel in Early HER-2 Negative Breast Cancer With Proteomic and Dynamic Imaging Correlates

Breast Cancer

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Acalabrutinib for the Treatment of Ibrutinib-Intolerant Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Hartford Hospital
Merck Sharp & Dohme LLC

Completed

Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections

Diabetes | Healthy Volunteers | Wound Infection

United States
Michael Bishay Shehata Keroles

Not yet recruiting

Duration of Analgesia in Bier Block for Patients Undergoing Hand Surgery

Regional Anesthesia

Egypt
Brii Biosciences Limited

Completed

A Study of BRII-296 in Adults With Severe Postpartum Depression (PPD)

Severe Postpartum Depression

United States
Acerta Pharma BV
National Institutes of Health (NIH)

Active, not recruiting

Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer (KEYNOTE166)

Carcinoma, Non-Small-Cell Lung

United States
M.D. Anderson Cancer Center

Active, not recruiting

Acalabrutinib and Rituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Seoul National University Hospital
Boston Scientific Korea Co. Ltd; Dio; Terumo Corporation; Abbott

Unknown

Harmonizing Optimal Strategy for Treatment of Coronary Artery Diseases Trial - Comparison of REDUCTION of PrasugrEl Dose & POLYmer TECHnology in ACS Patients (HOST REDUCE POLYTECH RCT Trial)

Acute Coronary Syndrome

Korea, Republic of
University of Chicago
National Cancer Institute (NCI)

Recruiting

Afatinib in Advanced Refractory Urothelial Cancer

Recurrent Bladder Cancer | Stage III Bladder Cancer | Stage IV Bladder Cancer | Ureter Cancer | Distal Urethral Cancer | Proximal Urethral Cancer | Recurrent Urethral Cancer | Stage III Urethral Cancer | Stage IV Urethral Cancer

United States
Boehringer Ingelheim

Completed

Dose Escalation Trial of BIBW 2992 Administration in Combination With Docetaxel in Patients With Advanced Solid Tumors

Neoplasms
Wyeth is now a wholly owned subsidiary of Pfizer
ViroPharma

Completed

Study Evaluating the Pharmacokinetics of the Potential Drug Interaction Between HCV-796 and Desipramine

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer
ViroPharma

Completed

A Study Evaluating the Safety and Clinical Activity of HCV-796 in Treatment-Naive and Non-Responder Subjects

Hepatitis C

United States, Puerto Rico
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma (KEYNOTE147)

Squamous Cell Carcinoma of the Head and Neck

United States
University of Pittsburgh
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Patients With Bile Duct, Gallbladder, or Pancreatic Cancer

Pancreatic Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Fred Hutchinson Cancer Center
AstraZeneca

Recruiting

Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Moderate-Severe Chronic Graft Versus Host Disease

United States
Boehringer Ingelheim

Completed

BIBW 2992 After Administration of Docetaxel in Patients With Advanced Solid Tumors

Neoplasms
University Hospital, Ghent

Withdrawn

Aruba Aloë Formula F-BC-096 in the Treatment of Split Thickness Donor Sites After Wound Closure

Hydration of Scars

Belgium
Herantis Pharma Plc.
Clinical Research Services Turku - CRST Oy

Completed

Single Ascending Doses of HER-096 in Healthy Subjects

Parkinson Disease

Finland
AbbVie
Merck Sharp & Dohme LLC

Terminated

A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Cancer - Acute Myeloid Leukemia

United States, Australia, Spain
Boehringer Ingelheim

Completed

Safety and PK Study of BIBF 1120 in Japanese Patients With IPF

Idiopathic Pulmonary Fibrosis

Japan
Jonsson Comprehensive Cancer Center
AstraZeneca

Recruiting

Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | High-grade B-cell Lymphoma | Transformed Lymphoma | Secondary Central Nervous System Lymphoma

United States

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