Search clinical trials for: BIBR 1048

Total 653 results

Daiichi Sankyo, Inc.

Terminated

CS-1008 Used With Irinotecan Versus Irinotecan Alone in Subjects With Metastatic Colorectal Carcinoma Who Failed First-line Treatment With Oxaliplatin

Metastatic Colorectal Cancer

United Kingdom
Mayo Clinic

Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic... and other conditions

United States
Boehringer Ingelheim

Completed

6 Weeks Treatment of Locally Advanced Breast Cancer With BIBW 2992 (Afatinib) or Lapatinib or Trastuzumab

Breast Neoplasms

United States, Brazil, Colombia, Peru
Merck Sharp & Dohme LLC

Recruiting

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004)

Non-small Cell Lung Cancer

United States
Bial - Portela C S.A.

Completed

Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Bosentan

Pulmonary Arterial Hypertension

Germany
Boehringer Ingelheim

Completed

Pharmacodynamics, Preliminary Pharmacokinetics and Tolerability of BIBB 515 BS or Pravastatin in Hyperlipemic Healthy Male Subjects

Healthy
Guangzhou Lupeng Pharmaceutical Company LTD.

Recruiting

A Study to Assess Safety and Preliminary Efficacy of LP-108 Combined With Azacitidine In Subjects With AML, MDS, CMML

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

China
Takeda

Completed

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

Colitis, Ulcerative

United States, Korea, Republic of, Netherlands, Australia, Denmark, Russian Federation, Spain, Croatia, Israel, Serbia, Bulgaria, Canada, Italy, Poland, Ukraine, Hungary, Belgium, Czechia, Turkey, Germany, Japan, Estonia, Mexico, Romania and more
University Hospital Olomouc

Completed

Perioperative Fluid Therapy With Balanced Crystalloids

Acid Base Imbalance
Stempeutics Research Pvt Ltd

Completed

Allogeneic Mesenchymal Stem Cells in Osteoarthritis

Osteoarthritis of Knee

India
Aziende Chimiche Riunite Angelini Francesco S.p.A
Mario Negri Institute for Pharmacological Research

Completed

The Effects of Bindarit in Diabetic Nephropathy

Diabetic Nephropathy

Italy, Slovenia
University of Colorado, Denver

Completed

Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach

Hypotension | Kidney Injury

United States
University of Zurich

Unknown

Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing and Sleep

Interstitial Lung Disease | Precapillary Pulmonary Hypertension

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal Disease

Metastatic Head and Neck Squamous Cell Carcinoma | Metastatic Squamous Cell Carcinoma in Cervical Lymph Node

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery

Glioblastoma

United States
Dracen Pharmaceuticals, Inc.

Terminated

Study to Investigate DRP-104 in Adults With Advanced Solid Tumors

Advanced Solid Tumor | Non Small Cell Lung Cancer Metastatic

United States, Taiwan, Germany, Singapore, Spain
Bayer

Completed

Test the Phototoxicity of Sunscreen Products

Sunscreen Agents

United States
Pronova BioPharma

Completed

Bioavailability of Omega-3 Food Supplements in Healthy Subjects

Healthy

United Kingdom
Austin Health

Unknown

Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluation (CHLORIDE)

Shock | Critical Illness

Australia
GUSTAVO SALGUERO
Hospital Infantil Universitario de San Jose

Not yet recruiting

Cartilage Recovery in Adults With Knee Osteorthritis by Mesenchymal Cell Therapy: Randomized Trial of Radiologic and Clinical Outcomes (INMUNOCEM-OA)

Knee Osteoarthritis
LaNova Medicines Limited

Terminated

Study of LM-108 as a Single Agent or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumours

Advanced Solid Tumor

United States
All India Institute of Medical Sciences, New Delhi
Postgraduate Institute of Medical Education and Research; Jawaharlal Institute... and other collaborators

Completed

Balanced Crystalloid vs. Saline in Children With Septic Shock

Shock | Septic Shock

India
Biocad

Completed

Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of Single Intravenous Doses of BCD-148 and Soliris®

Healthy Subjects

Russian Federation
Assistance Publique - Hôpitaux de Paris

Completed

Fluid Resuscitation in Burn Patients (CARE)

Severe Burns | Fluid Resuscitation

France
Fundación Santa Fe de Bogota

Unknown

Balanced Crystalloids in Postpartum Hemorrhage

Postpartum Hemorrhage

Colombia
CTI BioPharma

Withdrawn

Dose-Escalation Study of Pixantrone Monotherapy in Pediatric Patients With Relapsed or Refractory Cancer

Lymphoma | Solid Tumor (Excluding CNS)

United States
Asklepion Pharmaceuticals, LLC

Recruiting

A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Atrioventricular Septal Defect | Ventricular Septal Defect | Primum Atrial Septal Defect

United States
Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) Versus Chemotherapy as First Line Treatment in NSCLC With EGFR Mutation

Adenocarcinoma | Carcinoma, Non-Small-Cell Lung

Hong Kong, Canada, Korea, Republic of, Belgium, Australia, United States, Taiwan, United Kingdom, Germany, Italy, Japan, Austria, Thailand, Peru, Ireland, Russian Federation, Philippines, France, Brazil, Chile, Argentina, Hungary, M... and more
Aktion Bronchialkarzinom e.V.
Boehringer Ingelheim

Completed

An Dose Escalation Trial of Oral BIBF 1120 in Combination With Intravenous Carboplatin and Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer - Stage IV (VENUS-2) (VENUS-2)

Carcinoma, Non-Small-Cell Lung

Germany
Merck Sharp & Dohme LLC

Recruiting

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

Advanced Solid Tumors | Metastatic Solid Tumors

Canada, Switzerland, United States
Medical University of South Carolina
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells

Diabetes Mellitus, Type 1

United States
Charleston Laboratories, Inc

Completed

A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip

Pain | Nausea | Vomiting

United States
Organon and Co
CRS Mannheim GmbH

Completed

A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)

Healthy
Maximilian Diehn
Varian Medical Systems

Completed

SABR-ATAC: A Trial of TGF-beta Inhibition and Stereotactic Ablative Radiotherapy for Early Stage Non-small Cell Lung Cancer

Stage IA Non-Small Cell Lung Carcinoma | Stage IB Non-Small Cell Lung Carcinoma

United States
University of Zurich

Completed

Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance

Interstitial Lung Disease | Precapillary Pulmonary Hypertension

Switzerland
Boehringer Ingelheim

Completed

Phase I Open Label Trial to Assess Safety of BIBW 2992 (Afatinib) in Combination With Herceptin® in Patients With HER2-positive Advanced Breast Cancer.

Breast Neoplasms

United Kingdom
Boehringer Ingelheim

Completed

Dose Escalation of BIBF 1120 Combined With Pemetrexed in Advanced Non Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
University of Chicago
National Cancer Institute (NCI)

Terminated

Afatinib in Advanced Refractory Urothelial Cancer

Recurrent Bladder Cancer | Stage III Bladder Cancer | Stage IV Bladder Cancer | Ureter Cancer | Distal Urethral Cancer | Proximal Urethral Cancer | Recurrent Urethral Cancer | Stage III Urethral Cancer | Stage IV Urethral Cancer

United States
China National Biotec Group Company Limited
The University of Hong Kong; Beijing Institute of Biological Products Co Ltd.; Wuhan Institute of Biological Products Co., Ltd

Active, not recruiting

Sequential Immunization of Two Doses of Inactivated COVID-19 Vaccine (Omicron) in Vaccinated Population Aged 18 Years and Above (COVID-19)

COVID-19

Hong Kong
Bayer

Completed

To Test for Photo Allergy Reaction of Sunscreens

Photoallergy

United States
Regional Hospital Holstebro

Unknown

0,9% NaCl Effect on Kidney Function and Glycocalyx in Patients Operated on for Primary Hiparthrosis (KIPA)

Nephrotoxicity

Denmark
Aktion Bronchialkarzinom e.V.
Boehringer Ingelheim

Completed

An Dose Escalation Trial of Oral BIBF 1120 in Combination With Intravenous Vinorelbine in Elderly Patients With Advanced Non Small Lung Cell Cancer - Stage IV (VENUS-1) (VENUS-1)

Carcinoma, Non-Small-Cell Lung

Germany
University of Brawijaya
PT. Sahabat Lingkungan Hidup

Enrolling by invitation

Development The Potentiality of β-1,3/1,6-D-Glucan (Polysaccharide Peptide) From Mycelia Extract of Indonesia's Ganoderma Lucidum as Adjuvant Therapy in Patients With Cardiometabolic Syndrome

Cardiometabolic Syndrome

Indonesia
Daiichi Sankyo, Inc.

Completed

CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

Germany
Centre hospitalier de l'Université de Montréal...

Suspended

Crystalloid Fluids and Cardiac Surgery

Surgery-Complications

Canada
Charite University, Berlin, Germany
Bristol-Myers Squibb

Completed

Effect of Irbesartan on Insulin Sensitivity in Chronic Heart Failure

Chronic Heart Failure

Germany
FHI 360

Completed

Lower Dose Depo Provera® Contraceptive Injection

Contraception

Chile, Dominican Republic, Brazil
Pfizer
Valneva Austria GmbH

Completed

Study Assessing the Safety, Immunogenicity and Dose Response of VLA15, A New Vaccine Candidate Against Lyme Borreliosis

Lyme Borreliosis, Nervous System

Belgium, United States
Biocad

Completed

Clinical Trial of BCD-148 and Soliris® for the Treatment of Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Russian Federation
Vanderbilt University

Completed

Isotonic Solution Administration Logistical Testing (SALT)

Acute Kidney Injury

United States

Search clinical trials for: BIBR 1048

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