Search clinical trials for: Bempedoic Acid Ezetimibe Fixed-Dose Combination

Total 250 results

Esperion Therapeutics, Inc.

Completed

A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy

Hyperlipidemias

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia (MILOS)

Hypercholesterolemia | Mixed Dyslipidemia

Austria, United Kingdom, Italy, Germany, Belgium
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Withdrawn

Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia (MILOS-Spain)

Mixed Dyslipidemia | Primary Hypercholesterolemia
University of Western Ontario, Canada
Pfizer

Completed

STITCH (Simplified Therapeutic Intervention To Control Hypertension)

Hypertension

Canada
International Union Against Tuberculosis and Lung...
United States Agency for International Development (USAID)

Unknown

Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis

Tuberculosis

Algeria, Bolivia, Colombia, Guinea, Mozambique, Nepal, Peru, Tanzania, Vietnam
Esperion Therapeutics, Inc.

Recruiting

Bempedoic Acid Pregnancy Surveillance Program

Pregnancy | Hyperlipidemias

United States
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
NewAmsterdam Pharma

Completed

Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe

Healthy Volunteer Study

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of MK-0616 Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018)

Hypercholesterolemia
Esperion Therapeutics, Inc.

Completed

Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women

Healthy Lactating Women

United States
Rockefeller University
National Institute on Drug Abuse (NIDA)

Completed

Immunologic Effects of HCV Therapy With HARVONI in HCV Genotype 1 Chronically Mono-infected Active and Former IDUs

Hepatitis C

United States
Esperion Therapeutics, Inc.

Completed

Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C

Diabetes Mellitus, Type 2 | Diabetes | Cholesterolemia

United States
Kaiser Permanente
Esperion Therapeutics, Inc.

Not yet recruiting

Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study

Cardiovascular Diseases | STEMI | NSTEMI

United States
ANRS, Emerging Infectious Diseases
Gilead Sciences; Ministry of Health, Thailand; Assistance Publique - Hôpitaux... and other collaborators

Recruiting

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France. (SimpPrEP)

HIV/AIDS

France, Thailand
University Hospital, Clermont-Ferrand
Merck Sharp & Dohme LLC

Completed

Study to Investigate the Efficacy of Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in Treatment-Naïve, HCV GT1b-Infected Patients, With Non-severe Fibrosis (STREAGER)

Chronic HCV Infection

France
Janssen-Cilag S.p.A.

Completed

An Italian Observation of Antiretroviral Treatment in Participants Taking Darunavir/ Cobicistat Plus Emtricitabine and Tenofovir Alafenamide Fumarate (DIAMANTE)

Human Immunodeficiency Virus (HIV)

Italy
Jena University Hospital

Not yet recruiting

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target) (GoT)

ST Elevation Myocardial Infarction | Non-ST Elevation Myocardial Infarction | LDL-cholesterol

Germany
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Daiichi Sankyo Germany

Completed

SurveY Followed by a Retrospective Chart Review to Describe the Key Factors Leading to Physician's Decision to Treat Patients at High and Very High Cardiovascular Risk With hyperchOlesterolemia or Mixed Dyslipidemia With NUSTENDI®

Hypercholesterolemia | Mixed Dyslipidemia

Germany
American Regent, Inc.

Not yet recruiting

Tralement Versus a Fixed-dose Trace Element Combination Product of Zinc, Copper, and Selenious Acid to Evaluate Product Safety in Pediatric Patients >3 to 17 Years of Age Requiring Long-term Parenteral Nutrition

Manganese Safety in Pediatric Patients
Institute Of Cardiology & Internal Diseases, Kazakhstan
Merck Sharp & Dohme LLC; Synergy Research Group

Unknown

Open-Label Efficacy and Safety Study of the Elbasvir/ Grazoprevir Fixed Dose Combination Patients With Chronic HCV GT1b

Metabolic Syndrome | Fibrosis, Liver | Cirrhoses, Liver | Chronic Hepatitis C Genotype 1B

Kazakhstan
Novartis

Completed

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

Dyslipidemia

Germany, Switzerland
Massachusetts General Hospital
Merck Sharp & Dohme LLC

Completed

Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant

Renal Failure

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C

Hypercholesterolemia

United States
Macfarlane Burnet Institute for Medical Research...
St Vincent's Hospital Melbourne

Unknown

The TAP Study: Treating People Who Inject Drugs in Community-Based Settings Using a Social Network Approach (TAP)

Hepatitis C | Drug Abuse, Intravenous

Australia
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); Resolve to Save Lives; University...

Active, not recruiting

Transforming Hypertension Treatment in Nigeria Using a Type II Hybrid, Interrupted Time Series Design (HTN)

Hypertension

Nigeria
Laboratorios Silanes S.A. de C.V.

Completed

Study of no Pharmacokinetic Interaction Between Rosuvastatin 20mg and Ezetimibe10mg, Fixed Dose vs Individual Components

Healthy

Mexico
Raymond T. Chung, MD
Merck Sharp & Dohme LLC

Withdrawn

Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant

Hepatitis C | Cardiac Transplant Disorder

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)

Atherosclerosis | Hypercholesterolemia | Statin Adverse Reaction

United States
Aerie Pharmaceuticals

Completed

Rocklatan® Evaluation

Glaucoma

United States
Astex Pharmaceuticals, Inc.

Completed

Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndrome | MDS

United States, Canada
Laboratorios Silanes S.A. de C.V.

Completed

Study to Evaluate the Safety of the Fixed-dose Combination Rosuvastatin/Ezetimibe for Patients With Dyslipidaemia (TREZETE)

Dyslipidemias

Mexico
Kathleen Dungan
Novo Nordisk A/S

Completed

Prandial Insulin Dosing in Hospitalized Patients (ICHO)

Diabetes | Admitting Hospital | Non-critically Ill

United States
Fundacio Clinic Barcelona
Roche Pharma AG; SOLTI Breast Cancer Research Group

Recruiting

Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy (ELPIS)

Stage I Breast Cancer | HER2-positive Breast Cancer

Spain
Merck Sharp & Dohme LLC

Completed

An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus in Participants Who Are Co-Infected With Human Immunodeficiency Virus:C-EDGE CO-INFXN (MK-5172-061)

Chronic Hepatitis C
Korea University Anam Hospital

Recruiting

A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke

Dyslipidemias | Stroke, Acute Ischemic

Korea, Republic of
Duke University
Gilead Sciences

Completed

Hepatitis C Virus(HCV) Heart and Lung Study

Heart Failure | Pulmonary Disease, Chronic Obstructive | Hepatitis C, Chronic | Lung Diseases, Interstitial

United States
Shanghai Huaota Biopharmaceutical Co., Ltd.
M.D. Anderson Cancer Center; Dana-Farber Cancer Institute; Gabrail Cancer Center...

Recruiting

A Study of HB0045 Injection in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
Huabo Biopharm Co., Ltd.
M.D. Anderson Cancer Center; Dana-Farber Cancer Institute; Gabrail Cancer Center...

Not yet recruiting

A Study of HB0045 Injection in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
Epicentre
Medecins Sans Frontieres, Spain

Withdrawn

Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010

Child | Malnutrition | Malaria, Falciparum

Niger
Allergan

Completed

Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

Germany, Canada, United States, Austria
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Boehringer Ingelheim

Completed

Telmisartan80/HCTZ25 Versus Telmisartan80/HCTZ12.5 in Hypertension Not Responding to Telmisartan80/HCTZ12.5

Hypertension

France, Switzerland, Italy, Germany, Hong Kong, Netherlands, South Africa, Spain, Taiwan, Denmark, Sweden, Finland, Ireland, Korea, Republic of, Malaysia, Norway
National Institute of Allergy and Infectious Diseases...

Completed

Assessment of Pre-Exposure Prophylaxis (PrEP) Administered at Sexually Transmitted Disease (STD) Clinics

HIV Infections

United States
Aristotle University Of Thessaloniki

Completed

24-hour Intraocular Pressure (IOP) Control With the Bimatoprost/Timolol Fixed Combination (BTFC)

Glaucoma

Greece
Hue University of Medicine and Pharmacy
Università degli Studi di Sassari

Unknown

Lipid-lowering Therapies in Vietnamese Chronic Kidney Disease Population (VietCKD)

Chronic Kidney Diseases | Hypercholesterolemia

Vietnam
Bp Consulting, Inc
Allergan

Completed

Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Canada
GlaxoSmithKline

Completed

DUAC® Early Onset Efficacy Study in Japanese Subjects

Acne Vulgaris

Japan
Kirby Institute
The University of New South Wales

Completed

ALTAIR - Alternative Antiretroviral Strategies : a Comparison of Three Initial Regimens

Human Immunodeficiency Virus (HIV)
Michael Savona
Incyte Corporation; Astex Pharmaceuticals, Inc.; Theradex

Recruiting

Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO) (ABNL-MARRO)

MDS/MPN

United States
Organon and Co
Merck Sharp & Dohme LLC

Completed

Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)

Hypercholesterolemia | Hyperlipidemia

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