Search clinical trials for: Beta-lactamase inhibitor

Total 69162 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Vancomycin-Resistant Enterococci in a Hematology Unit

Gram-Positive Bacterial Infections

Korea, Republic of
Versailles Hospital

Unknown

Short Duration Treatment of Non-severe Community Acquired Pneumonia (PTC)

Community Acquired Pneumonia

France
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous RPX7009 in Healthy Adult Subjects

Bacterial Infections | Healthy Volunteers

Australia
First Affiliated Hospital Xi'an Jiaotong University
Second Affiliated Hospital of Xi'an Jiaotong University

Completed

Safety and Efficacy of Vancomycin Plus Beta-lactams (SEVPB)

Critical Illness

China
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety Study of Intravenous Biapenem (RPX2003) and RPX7009 Given Alone and in Combination

Bacterial Infections | Healthy Volunteers

Australia
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous RPX2014 and RPX7009 in Healthy Adult Subjects

Bacterial Infections | Healthy Volunteers

Australia
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Recruiting

Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections (TANGOKIDS)

Bacterial Infections

United States
Allecra

Completed

Investigation of AAI101 Safety, Tolerability & PK in Healthy Volunteers

Healthy
Swiss National Fund for Scientific Research
University Hospital, Geneva

Completed

Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia (BICAP)

Community-acquired Pneumonia

Switzerland
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Completed

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Urinary Tract Infection Complicated | Hospital Acquired Bacterial Pneumonia | Abdominal Infection

Italy, United States, Colombia, Greece, Israel, Brazil, Argentina, United Kingdom
Sara Thønnings

Withdrawn

Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia

Bacteremia
National Taiwan University Hospital

Unknown

Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill Patients

Gram-Negative Bacterial Infections

Taiwan
Universidad Complutense de Madrid

Completed

Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis

Mastitis

Spain
Mayo Clinic

Completed

Negative Predictive Value and NIC of Beta-Lactam Antibiotics.

Allergy

United States
Groupe Hospitalier Paris Saint Joseph

Recruiting

Evaluation of Pharmacokinetic / Pharmacodynamic and Tolerance Assessment of Dermal Administration of Beta-lactams in the Elderly (BETALACUTANE)

Beta-Lactams | Aged Subject

France
Hoffmann-La Roche

Completed

A Study to Assess Beta-Lactam in the Treatment of Hospitalized Patients With Bacterial Pneumonia

Pneumonia, Bacterial

United States, Romania, Chile, Slovakia, Hungary, Bulgaria, Latvia, Croatia, Peru, Lithuania, Argentina
Hoffmann-La Roche

Completed

A Study of Beta-Lactam in Hospitalized Patients With Skin and Skin Structure Infections

Soft Tissue Infections

United States, Estonia, Peru, Germany, Bulgaria, South Africa, Latvia, Lithuania, Argentina, Hungary, Romania
Meir Medical Center

Completed

Extended Open Challenge in Patients With a History of Drug Eruption Following Beta-lactam Treatment

Beta-lactam Allergy

Israel
Qianfoshan Hospital

Completed

Risk Factors and Machine Learning Model for Beta-Lactam Drugs Related Acute Kidney Injury

Acute Kidney Injury | Beta-Lactam Antibiotic Toxicity (Diagnosis)

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Single Doses of BLI-489 in Healthy Japanese Male Subjects

Healthy

Japan
First Affiliated Hospital of Zhejiang University

Recruiting

Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

Severe Sepsis

China
University Hospital, Grenoble

Not yet recruiting

Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients (KAMELOT)

Infections | Cardiac Arrest | Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication | Post-cardiac Surgery

France
Singapore General Hospital

Recruiting

Beta-lactam Therapeutic Drug Monitoring in Singapore (BLAST-2)

Infection, Bacterial

Singapore
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Evaluate Whether BLI-489 Can be Safely Tolerated by Healthy Subjects Given Multiple Doses

Healthy

United States
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Pharmacodynamics Modeling to Optimize Dosage Regimens of Sulbactam in Patients With Acinetobacter Infections

Acinetobacter Infections

Thailand
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Single Doses of BLI-489 in Healthy Subjects

Healthy Subjects

United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult Subjects

Bacterial Infections

United States
Stanford University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

The Use of Prophylactic Antibiotics In the Management of Dog Bites

Infection | Wound | Bite

United States
Chris Goss
Medical University of South Carolina; University of Washington; Cystic Fibrosis...

Recruiting

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study (STOP360AG)

Cystic Fibrosis | Cystic Fibrosis Pulmonary Exacerbation

United States, Canada
Menzies School of Health Research
The University of Queensland; Australasian Society for Infectious Diseases; Singapore... and other collaborators

Terminated

Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection (CAMERA2)

Methicillin-Resistant Staphylococcus Aureus

Australia, New Zealand, Israel, Singapore
Guangzhou Institute of Respiratory Disease

Recruiting

Bacteriology and Inflammation in Bronchiectasis (BISER)

Bronchiectasis

China
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Entasis Therapeutics
Clinartis

Completed

Study to Determine and Compare Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam in Healthy Subjects

Healthy

United States
Pfizer

Completed

A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and Separately

Healthy

United Kingdom
Imperial College London

Completed

Beta-lactam Pharmacokinetics in Secondary Care

Pharmacokinetics | Penicillin Allergy | Beta Lactam Adverse Reaction

United Kingdom
Pfizer

Completed

A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization

Pneumonia, Bacterial

United States, Australia, Canada, Korea, Republic of, Poland
Hartford Hospital
Merck Sharp & Dohme LLC

Completed

Imipenem-Relebactam Pharmacokinetics in Augmented Renal Clearance

Sepsis

United States
Assiut University

Not yet recruiting

Prophylactic Antibiotic in Non-complicated Low Risk Lap Cholecystectomy (LC)

Cholecystectomy, Laparoscopic
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV

Bacterial Infections

Australia, United States
Tribhuvan University, Nepal

Completed

Does Antibiotics Use During Surgery Help to Decrease Wound Infection and Increase Success After Ear Surgery in Children

Post Operative Wound Infection | Graft Uptake | Myringoplasty
GlaxoSmithKline

Not yet recruiting

A Pharmacokinetics and Safety Study of Augmentin ES-600 in Children With CAP and ABRS

Infections, Bacterial
Pfizer

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]NXL104

Healthy

United Kingdom
Pfizer

Completed

Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal Impairment

Renal Insufficiency

United States
Pfizer

Completed

Study to Assess the Pharmacokinetics, Safety and Tolerability of Aztreonam-Avibactam in Healthy Chinese Participants.

Healthy

China
Wake Forest University Health Sciences
Merck Sharp & Dohme LLC

Withdrawn

Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections

Gram-Negative Bacterial Infections | Antibiotic Resistant Infection | Carbapenem-Resistant Enterobacteriaceae Infection | KPC

United States
Haiphong University of Medicine and Pharmacy

Completed

Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD (COPD)

COPD Exacerbation Acute

Vietnam
University Hospital, Rouen

Recruiting

Population Pharmacokinetic Modeling to Optimize the Dosage of the Piperacillin / Tazobactam Combination in Patients With Sepsis in Intensive Care (OPT-TAZ)

Resuscitation Patients With Sepsis

France
GlaxoSmithKline
Iqvia Pty Ltd

Completed

Study to Evaluate the Safety and Clinical Efficacy of Augmentin® Extra Strength-600 in Children With Acute Otitis Media in India

Respiratory Tract Infections | Otitis Media | Infections, Respiratory Tract

India
Pfizer

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of NXL104 Alone and in Combination With Ceftazidime Administered as Single and Repeated Intravenous Doses in Healthy Japanese Subjects

Healthy Male and Female Japanese Volunteers

United States

Search clinical trials for: Beta-lactamase inhibitor

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