Search clinical trials for: Brimonidine/Timolol mixed combination

Total 328 results

Almirall, S.A.
proDERM GmbH

Completed

Efficacy and Tolerability of LAS41004 Formulations in a Non-occlusive Psoriasis Plaque Test (PPT4)

Psoriasis

Germany
Alcon, a Novartis Company

Completed

Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Ocular Hypertension | Open-Angle Glaucoma

Japan
Genovate Biotechnology Co., Ltd.,
Allergan Medical

Unknown

Combigan Ophthalmic Solution(Brimonidine 0.2% and Timolol 0.5%)With Latanoprost Compared With Latanoprost Monotherapy

Glaucoma

Taiwan
Alcon Research

Completed

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Aristotle University Of Thessaloniki

Completed

24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed Combinations

Open-angle Glaucoma

Greece
Kanecia Obie Zimmerman
National Institutes of Health (NIH); The Emmes Company, LLC

Completed

Efficacy, Safety and Pharmacokinetics of Topical Timolol in Infants With Infantile Hemangioma (IH) (TIM01)

Infantile Hemangioma

United States
University of Sao Paulo General Hospital

Completed

Transconjunctival Needling Revision Versus Medical Treatment

Primary Open Angle Glaucoma

Brazil
Alcon Research

Completed

Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Rockefeller University
National Institute on Drug Abuse (NIDA)

Completed

Immunologic Effects of HCV Therapy With HARVONI in HCV Genotype 1 Chronically Mono-infected Active and Former IDUs

Hepatitis C

United States
Oregon Health and Science University

Terminated

Topical Timolol 0.5% Solution for Proliferating Infantile Hemangiomas

Hemangioma | Infant

United States
EMS

Completed

BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension

Ocular Hypertension | Primary Open-angle Glaucoma

Brazil
Alcon Research

Completed

Patient Preference Study

Ocular Hypertension | Glaucoma
McMaster University

Withdrawn

Prophylaxis for Anti-VEGF-induced IOP Elevation

Ocular Hypertension
Cornerstone Health Care, PA
Allergan

Completed

Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID)

Ocular Hypertension | Glaucoma

United States
University Hospital, Clermont-Ferrand
Merck Sharp & Dohme LLC

Completed

Study to Investigate the Efficacy of Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in Treatment-Naïve, HCV GT1b-Infected Patients, With Non-severe Fibrosis (STREAGER)

Chronic HCV Infection

France
Merck Sharp & Dohme LLC

Completed

COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED)

Glaucoma
Mashhad University of Medical Sciences

Completed

Effect of Antiglaucoma Agents on Short Term Intraocular Pressure Fluctuations After Intravitreal Bevacizumab Injection

Intraocular Pressure Change in Intravitreal Injection

Iran, Islamic Republic of
Raymond T. Chung, MD
Merck Sharp & Dohme LLC

Withdrawn

Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant

Hepatitis C | Cardiac Transplant Disorder

United States
University of California, San Francisco
National Institutes of Health Clinical Center (CC); Johns Hopkins University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant (STOP-CO)

Hepatitis C | HIV | Cirrhosis

United States
Janssen-Cilag S.p.A.

Completed

An Italian Observation of Antiretroviral Treatment in Participants Taking Darunavir/ Cobicistat Plus Emtricitabine and Tenofovir Alafenamide Fumarate (DIAMANTE)

Human Immunodeficiency Virus (HIV)

Italy
Alisyn Facemire
ORA, Inc.

Completed

Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia

Eye Diseases | Refractive Errors | Presbyopia | Miosis | Near Vision

United States
Institute Of Cardiology & Internal Diseases, Kazakhstan
Merck Sharp & Dohme LLC; Synergy Research Group

Unknown

Open-Label Efficacy and Safety Study of the Elbasvir/ Grazoprevir Fixed Dose Combination Patients With Chronic HCV GT1b

Metabolic Syndrome | Fibrosis, Liver | Cirrhoses, Liver | Chronic Hepatitis C Genotype 1B

Kazakhstan
Chiesi Italia

Completed

Triple Therapy in Real-life: Impact on Adherence and Health Status (TRITRIAL)

COPD

Italy
Alcon Research

Completed

Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension

Glaucoma

United States
Gilead Sciences

Completed

Safety and Efficacy of LDV/SOF Fixed-Dose Combination (FDC) ± Ribavirin in HCV Genotype 1 Subjects

Chronic Hepatitis C Virus

United States
Merck KGaA, Darmstadt, Germany

Completed

Bioequivalence and Drug - Drug Interaction Study of Metformin/Gliclazide in Healthy Participants

Healthy

Germany
Merck KGaA, Darmstadt, Germany

Completed

A Study to Assess the Food Effect on Bioavailability of Metformin/Gliclazide in Healthy Participants

Healthy

Mexico
University of Michigan
Merck Sharp & Dohme LLC

Completed

Effect of Myocilin Genetic Variants on Intraocular Pressure and Pressure Variation in Sitting and Supine Positions (Myoc Gene)

Glaucoma

United States
ANRS, Emerging Infectious Diseases
Gilead Sciences; Ministry of Health, Thailand; Assistance Publique - Hôpitaux... and other collaborators

Recruiting

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France. (SimpPrEP)

HIV/AIDS

France, Thailand
Massachusetts General Hospital
Merck Sharp & Dohme LLC

Completed

Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant

Renal Failure

United States
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Efficacy Study of LNZ101 for the Treatment of Presbyopia (CLARITY)

Eye Diseases | Presbyopia | Miosis | Near Vision

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Recruiting

Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia

Eye Diseases | Presbyopia | Miosis | Near Vision

China
Allergan

Completed

Safety and Efficacy of Bimatoprost/Timolol Fixed Combination Versus Latanoprost in Patients With Open-Angle Glaucoma Who Have Never Been Treated

Glaucoma, Open-Angle

Spain, Portugal
Indiana University

Completed

Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data

Glaucoma

United States
Epicentre
University of Cape Town; Malaria Research and Training Center, Bamako, Mali

Completed

Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children (MAL-NUT)

Malaria | Severe Acute Malnutrition

Mali, Niger
Fakultas Kedokteran Universitas Indonesia

Recruiting

Proportion of Clinical Improvement & Type 1 Interferon (IFN) Score Changes in Idiopathic Uveitis Patients With Interferon Gamma Release Assay (IGRA) Positive

Anti-Tuberculous Drug Reaction | Tuberculous Uveitis | Tuberculosis; Uveitis (Manifestation)

Indonesia
Macfarlane Burnet Institute for Medical Research...
St Vincent's Hospital Melbourne

Unknown

The TAP Study: Treating People Who Inject Drugs in Community-Based Settings Using a Social Network Approach (TAP)

Hepatitis C | Drug Abuse, Intravenous

Australia
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); Resolve to Save Lives; University...

Active, not recruiting

Transforming Hypertension Treatment in Nigeria Using a Type II Hybrid, Interrupted Time Series Design (HTN)

Hypertension

Nigeria
Aerie Pharmaceuticals

Completed

Rocklatan® Evaluation

Glaucoma

United States
Abbott

Completed

A 12-week Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate/Simvastatin 145/20mg and Fenofibrate/Simvastatin 145/40mg Tablets Versus Fenofibrate or Simvastatin Monotherapies in Subjects With Abnormal Blood Levels of Fats (Lipids) and at High Risk of Cardiovascular Disease

Dyslipidemia

Argentina, Czech Republic, Germany, Mexico, Poland, Romania, Russian Federation
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Safety Study for the Treatment of Presbyopia Subjects

Eye Diseases | Presbyopia | Miosis | Near Vision

United States
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia

Eye Diseases | Refractive Errors | Presbyopia

United States
Duke University
Gilead Sciences

Completed

Hepatitis C Virus(HCV) Heart and Lung Study

Heart Failure | Pulmonary Disease, Chronic Obstructive | Hepatitis C, Chronic | Lung Diseases, Interstitial

United States
Fundacio Clinic Barcelona
Roche Pharma AG; SOLTI Breast Cancer Research Group

Recruiting

Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy (ELPIS)

Stage I Breast Cancer | HER2-positive Breast Cancer

Spain
NewAmsterdam Pharma

Completed

Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe

Healthy Volunteer Study

United States
Merck Sharp & Dohme LLC

Completed

An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus in Participants Who Are Co-Infected With Human Immunodeficiency Virus:C-EDGE CO-INFXN (MK-5172-061)

Chronic Hepatitis C
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination (FDC) for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic HCV Infection

Hepatitis C Virus Infection

France, Austria, Germany, Italy
Allergan

Completed

Safety and Efficacy of LUMIGAN® RC Versus DuoTrav® in Patients Who Require Further Intraocular Pressure (IOP) Reduction

Ocular Hypertension | Glaucoma, Open-Angle

Canada
Boehringer Ingelheim

Completed

Open Label Study Telmisartan and Amlodipine in Hypertension

Hypertension

Belgium, Canada, Denmark, Finland, France, Korea, Republic of, Netherlands, Norway, Philippines, South Africa, Sweden, Taiwan

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