Search clinical trials for: Brolucizumab ophthalmic solution

Total 19620 results

Alcon Research

Not yet recruiting

A Double-Masked Comparison of FID 123320 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness

Ocular Redness

United States
Keith G. LeBlanc, Jr, MD

Recruiting

Topical Timolol: a Comparison of Surgical Outcomes

Wound Heal

United States
Allergan

Completed

A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia (GEMINI 2)

Presbyopia

United States
Allergan

Completed

Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia (GEMINI 1)

Presbyopia

United States
Robert Mack, M.D.

Unknown

Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2

Keratoconus | Corneal Ectasia

United States
Bausch & Lomb Incorporated

Completed

Safety/Efficacy of Bromfenac Ophthalmic Solution for Ocular Inflammation and Pain Associated With Cataract Surgery

Pain | Inflammation

United States
Wills Eye

Recruiting

A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR

Rhegmatogenous Retinal Detachment | Proliferative Vitreoretinopathy

United States
Fayoum University

Completed

The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of POAG Using OCTA

Glaucoma, Primary Open Angle | Ocular Blood Flow | Optical Coherence Tomography Angiography

Egypt
Bausch & Lomb Incorporated

Completed

Efficacy Study of Ecabet Ophthalmic Solution in Dry Eye Disease

Dry Eye Disease

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Therapeutic Effect of Stem Cell Eye Drops on Dry Eye Disease

Dry Eye Syndromes | Mesenchymal Stem Cell
University of Rochester
Livionex Inc

Completed

A Pilot Study to Assess the Preliminary Efficacy of EDTA Eye Drops on Band Keratopathy

Corneal Dystrophy, Band-Shaped

United States
Boston Medical Center

Completed

Efficacy of Glaucoma Drop Aids in Medication Compliance in the Patient Population at Boston Medical Center

Glaucoma

United States
GlaxoSmithKline

Terminated

12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD)

Macular Degeneration

United States, France, Germany
Sanofi

Completed

28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma -Ocular Hypertension

United States
Mati Therapeutics Inc.

Withdrawn

A Phase 2 Study of the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Glaucoma
Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
University of Waterloo
Novartis

Recruiting

The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers (COLLIE)

Dry Eye

Canada
University of Alabama at Birmingham
Shire

Withdrawn

Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers

Contact Lens Dry Eye

United States
Mati Therapeutics Inc.

Completed

A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open Angle Glaucoma

Canada
Singapore National Eye Centre

Completed

Use of Autologous Serum Eye-drops as Tears in Patients With Recalcitrant Dry Eye

Xerophthalmia

Singapore
Alcon Research

Completed

Tobramycin Tear Concentrations

Dry Eye

United States
Massachusetts Eye and Ear Infirmary

Completed

Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty

Fuchs' Endothelial Dystrophy

United States
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Ocuphire Pharma, Inc.
Viatris Inc.

Recruiting

Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances (LYNX-2)

Mesopic Vision | Night Vision Loss

United States
Joseph B. Ciolino, MD

Not yet recruiting

A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients (EVOKE)

Keratoconus

United States
Laboratorios Sophia S.A de C.V.

Completed

Safety and Tolerability of the PRO-174 Versus Sophixín Ofteno®, on the Ocular Surface of Healthy Subjects (PRO-174/I)

Conjunctivitis | Conjunctivitis, Bacterial

Mexico
Guangzhou HuiBoRui Biological Pharmaceutical Technology...
Parexel

Unknown

Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment

Corneal Neovascularization

United States
Sun Pharmaceutical Industries Limited

Completed

Effect of Cequa™ in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Boston Sight
Allergan

Completed

Novel Use of Cyclosporine Ophthalmic Emulsion 0.05% on Application of PROSE Devices for Management of Patients With Ocular Surface Disease

Ocular Surface Disease

United States
Starr Muscle
Ohr Pharmaceutical Inc.

Withdrawn

Squalamine Lactate Eye Drops in Combination With Ranibizumab in Patients With Diabetic Macular Edema (DME)

Diabetic Retinopathy

United States
Tarsier Pharma

Completed

A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis

Non-infectious Anterior Uveitis

United States
Novartis Pharmaceuticals

Withdrawn

Examining the Clinical Characteristics, Treatment Patterns, Real-world Effectiveness, and Healthcare Resource Utilization of Patients With Dry Eye Disease

Dry Eye Disease
C.O.C. Farmaceutici S.r.l.

Completed

PMCF Study to Evaluate Performance and Safety of "LUXIDROPIN BABY & JUNIOR"

Ocular Discharge

Italy
C.O.C. Farmaceutici S.r.l.

Completed

PMCF Study to Evaluate Performance and Safety of "Xanoftal Next"

Dry Eye | Allergic Conjunctivitis | Dry Eye Disease

Italy
Taejoon Pharmaceutical Co., Ltd.

Completed

A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients

Ocular Hypertension | Primary Open-angle Glaucoma

Korea, Republic of
Aristotle University Of Thessaloniki

Completed

Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure (CCT-IOP)

Ocular Hypertension | Open Angle Glaucoma

Greece
Mati Therapeutics Inc.

Completed

Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension (CORE)

Ocular Hypertension | Glaucoma

United States
Advanced Glaucoma Specialists
Merck Sharp & Dohme LLC

Unknown

Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.

Open Angle Glaucoma

United States
Allergan

Completed

A Study to Compare a New Eye Drop Formulation With Refresh Contacts®

Contact Lens Lubrication

United States
Santen Inc.

Completed

Ocular Availability in Human Tears After Topical Administration of 1.5% Levofloxacin Compared to Active Comparators

Healthy

United States
University of Kansas Medical Center

Completed

A Randomized Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine

Migraine

United States
American-European Congress of Ophthalmic Surgery

Terminated

Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery

Keratoconus | Corneal Ectasia

United States, Puerto Rico
Massachusetts Eye and Ear Infirmary

Not yet recruiting

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

Rhegmatogenous Retinal Detachment | Proliferative Vitreoretinopathy
Shire

Completed

Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1) (OPUS-1)

Keratoconjunctivitis Sicca | Dry Eye Disease

United States
Chengdu Kanghong Biotech Co., Ltd.

Unknown

An Exploratory Clinical Trial Evaluating the Tolerability and Efficacy of KH906 in Patients With Corneal Neovascularization

Corneal Neovascularization

China
Nephron Pharmaceuticals Corporation

Completed

Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Novaliq GmbH

Completed

NovaTears® Eye Drops Observational Study NT-002

Dry Eye Syndromes

Germany
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Alcon Research

Completed

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma

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