Search clinical trials for: CC-97489

Total 833 results

Virginia Commonwealth University
National Cancer Institute (NCI); Celgene Corporation

Completed

Lenalidomide + Azacitidine for Adaptive Immunotherapy -> Auto SCT in Multiple Myeloma

Multiple Myeloma

United States
Timothy R Petersen

Withdrawn

Pectoral Nerve Blockade in Mastectomy

Breast Cancer | Postoperative Pain

United States
University of Calgary

Completed

Postoperative Systemic Corticosteroids When Utilizing a Steroid-Eluting Spacer Following Endoscopic Sinus Surgery

Chronic Sinusitis | Steroids | Endoscopic Sinus Surgery | Post-operative Care | Drug-eluting Spacer

Canada
National Cancer Institute (NCI)

Completed

Paclitaxel and CBT-1(Registered Trademark) to Treat Solid Tumors

Lung | Breast | Ovarian | Cervical | Renal

United States
Boston Children's Hospital

Not yet recruiting

Lidocaine Versus Bupivacaine in Orthognathic Surgery

Pain, Postoperative | Numbness | Temperature Sensation | Perception of Touch
Celgene

Recruiting

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Lymphoma, B-Cell

United States, Greece, Spain, Australia, Poland, Taiwan, Korea, Republic of
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States, Canada
Sultan Abdulhamid Han Training and Research Hospital...

Recruiting

Investigation of the Effect of Central Sensitization (CS) on Steroid Injection Response in Rotator Cuff Lesion (CS)

Subacromial Impingement Syndrome | Central Sensitisation

Turkey
Canadian Myeloma Research Group

Not yet recruiting

Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients (BOREALIS)

Multiple Myeloma
Ohio State University Comprehensive Cancer Center
MorphoSys AG

Active, not recruiting

Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL

Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Contiguous Stage II Small Lymphocytic... and other conditions

United States
M.D. Anderson Cancer Center
Incyte Corporation

Completed

Ruxolitinib and Lenalidomide for Patients With Myelofibrosis

Myeloproliferative Diseases

United States
Bagcilar Training and Research Hospital

Completed

Incremental Clomiphene Citrate Doses in Successive Cycles and FSH, LH and Steroid Hormone Levels

Unexplained Infertility | Ovulation Disorder

Turkey
Tufts Medical Center
Immune Control

Completed

Fluphenazine Hydrochloride for Psoriasis (FP-CL2)

Psoriasis

United States
Kenneth Peters, MD
Celgene Corporation

Completed

An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Prostatitis | Chronic Prostatitis With Chronic Pelvic Pain Syndrome

United States
Mansoura University

Completed

Efficacy of Letrozole and CC Alone in an IUI Program in Cases With Surgically Treated Minimal to Mild Endometriosis

Endometriosis

Egypt
Amgen

Completed

A Study to Evaluate the Impact of Apremilast on Magnetic Resonance Imaging (MRI) Outcomes in Adults With Psoriatic Arthritis (MOSAIC)

Psoriatic Arthritis

Spain, Belgium, Denmark, United States, Germany, Russian Federation, Austria, United Kingdom, Canada, Italy, Switzerland
Amgen

Completed

Apremilast Safety and PK Study in Recalcitrant Plaque Psoriasis

Psoriasis-Type Psoriasis | Plaque-Type Psoriasis

United States
Celgene

Completed

A Study Being Conducted at Multiple Locations to Compare Safety and Efficacy of Three Different Regimens; (1) High-Dose Lenalidomide; (2) Lenalidomide + Azacitidine; or (3) Azacitidine in Subjects ≥ 65 Years With Newly-Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States, Canada
University Hospitals Cleveland Medical Center
Celgene Corporation

Completed

Safety and Efficacy of CC-10004 for Prurigo Nodularis

Prurigo Nodularis

United States
Kenneth Peters, MD
Celgene Corporation

Completed

CC-10004 For The Treatment Of Vulvodynia

Vulvodynia

United States
Duke University

Withdrawn

Apremilast for Chronic Plaque Psoriasis (CPP) Patients Who Have Failed One Course of Biologic Therapy

Chronic Plaque Psoriasis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Celgene

Recruiting

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome With Excess Blasts | IDH2 Gene Mutation | Recurrent High Risk Myelodysplastic Syndrome | Refractory High Risk Myelodysplastic Syndrome | Blasts 20-30 Percent of Bone Marrow Nucleated Cells

United States
Amgen

Active, not recruiting

A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis

Psoriasis

Belgium, Spain, United States, Czechia, Italy, Russian Federation, Canada, France, Israel
Amgen

Completed

An Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate to Severe Genital Psoriasis (DISCREET)

Psoriasis

United States, Belgium, Italy, France, Germany, Puerto Rico, Canada
The Lymphoma Academic Research Organisation
Celgene

Active, not recruiting

Efficacy and Safety of Oral Azacitidine Compared to Investigator's Choice Therapy in Patients With Relapsed or Refractory AITL

Relapsed Angioimmunoblastic T-Cell Lymphoma | Refractory Angioimmunoblastic T-cell Lymphoma

France, Denmark, United Kingdom, Austria, Belgium
Amgen

Completed

A Study to Describe the Characteristics of Patients Treated With Apremilast for Plaque Psoriasis in Italian Routine Clinical Practice (DARWIN)

Plaque Psoriasis

Italy
Benha University

Completed

Silodosin, Tadalafil Alone vs. Silodosin Plus Tadalafil as MET for Lower Ureteric Stones

Lower Ureteric Stones | Medical Expulsive Therapy | Tadalafil | Silodosin

Egypt
Amgen

Completed

A Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Adults With Manifestations of Plaque Psoriasis and Impaired Quality of Life (EMBRACE)

Psoriasis

France, Italy, Spain, United Kingdom, Switzerland, Germany
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease

Behcet Syndrome

United States, Turkey
Amgen

Completed

A Study of Safety, Tolerability and Pharmacokinetics of Apremilast (CC-10004) in Pediatric Subjects With Moderate to Severe Plaque Psoriasis

Psoriasis

Canada, Spain, United States, Germany
Georgetown University
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer

Advanced Solid Tumors

United States
SCRI Development Innovations, LLC
Celgene Corporation

Completed

CC-4047 With Gemcitabine for Untreated Advanced Carcinoma of the Pancreas

Pancreatic Cancer

United States
Celgene

Recruiting

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (EXCALIBER-RRMM)

Multiple Myeloma

Austria, Italy, China, Australia, Spain, United States, Korea, Republic of, Taiwan, Germany, Ireland, Argentina, Brazil, Mexico, Netherlands, Belgium, Czechia, France, Greece, Japan, Poland, Israel, United Kingdom, Norway, Denmark, Finland and more
OHSU Knight Cancer Institute
Sanofi; Oregon Health and Science University

Active, not recruiting

Isatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Japanese Subjects With Palmoplantar Pustulosis

Palmoplantaris Pustulosis

Japan
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Montefiore... and other collaborators

Active, not recruiting

Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection

Human Immunodeficiency Virus 1 Positive | Skin Kaposi Sarcoma

Uganda, Kenya, Malawi
Amgen

Completed

A Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Moderate to Severe Plaque Psoriasis of the Scalp (STYLE)

Psoriasis

United States, Canada
Amgen

Completed

Efficacy and Safety Study of Apremilast to Treat Active Ulcerative Colitis (UC)

Ulcerative Colitis

Russian Federation, United States, France, Australia, Czechia, New Zealand, Germany, Italy, Poland, Hungary, Netherlands, Ukraine, Bulgaria, Canada
M.D. Anderson Cancer Center

Completed

Lenalidomide and High-Dose Melphalan

Stem Cell Transplantation | Myeloma

United States
National Cancer Institute (NCI)

Completed

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
Celgene Corporation
Prologue Research International

Terminated

A Phase I/II Study of Lenalidomide in Combination With Gemcitabine in Patients With Untreated Advanced Carcinoma of the Pancreas

Pancreatic Cancer

United States
Celgene

Active, not recruiting

A Study to Determine Dose, Safety, Tolerability, Drug Levels, and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Participants With Multiple Myeloma

Multiple Myeloma

United States, Australia, Canada, France, Germany, Israel, Italy, Japan, Netherlands, Spain, United Kingdom
Andrei Iagaru
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

HDR Brachytherapy 68-Ga-RM2 PET, 68-Ga-PSMA-11 PET &Multi Parametric MRI in Prostate Cancer

Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Obinutuzumab and Lenalidomide in Treating Patients With Previously Untreated Stage II-IV Grade 1-3a Follicular Lymphoma

Fatigue | Weight Loss | Fever | Splenomegaly | Ann Arbor Stage II Grade 1 Follicular Lymphoma | Ann Arbor Stage II Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1... and other conditions

United States
George Washington University
Celgene Corporation

Withdrawn

Apremilast and Moderate to Severe Chronic Hand Dermatitis (CHD)

Chronic Hand Dermatitis

United States
Amgen

Completed

Effects of Age and Sex on the Pharmacokinetics of Apremilast in Healthy Adults

Healthy Volunteer

United States
Amgen

Completed

Phase II Study of Apremilast (CC-10004) in Adults With in Psoriatic Arthritis

Psoriatic Arthritis

Belgium, Canada, United Kingdom, Germany, Netherlands
University of Wisconsin, Madison
Celgene Corporation

Completed

Study of Bendamustine/Rituxan Induction Chemotherapy With Revlimid Maintenance for Relapsed/Refractory CLL and SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Andrei Iagaru
General Electric

Completed

68Ga PSMA 11 PET/MRI and 68Ga RM2 PET/MRI for Biopsy Guidance in Patients With Suspected Prostate Cancer

Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Lenalidomide and Obinutuzumab in Treating Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | Refractory Small Lymphocytic Lymphoma

United States

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