Search clinical trials for: CIML NK Cells plus KP1237 and low dose IL-2

Total 70 results

Biohaven Pharmaceuticals, Inc.
Dana-Farber Cancer Institute

Recruiting

Autologous Memory-like NK Cell Therapy With BHV-1100 (Formerly KP1237), Low Dose IL-2 in Multiple Myeloma Patients

Multiple Myeloma

United States
University of Minnesota

Completed

Adoptive Transfer of Haploidentical Natural Killer Cells and IL-2

HIV

United States
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Safety Study of NK Cells From Sibship to Treat the Recurrence of HCC After Liver Transplantation

Hepatocellular Carcinoma

China
Technical University of Munich

Completed

Targeted Natural Killer (NK) Cell Based Adoptive Immunotherapy for the Treatment of Patients With Non-Small Cell Lung Cancer (NSCLC) After Radiochemotherapy (RCT)

NSCLC Stage IIIA/B

Germany
University Hospital, Limoges

Withdrawn

Treatment of Steroid Dependent Idiopathic Nephrotic Syndrome in Children With Low Doses of Interleukin 2: a Pilot Study (NIL-2 pilote)

Nephrotic Syndrome Steroid-Dependent | Interleukin 2
HeJing

Completed

Low-dose IL-2 Treatment on Behcet's Disease

Behcet's Disease

China
University of Virginia

Completed

Trial for the Evaluation of the Effect of Systemic Low-dose Interleukin-2 (IL-2) on the Immunogenicity of a Vaccine Comprising Synthetic Melanoma Peptides Administered With Granulocyte-macrophage Colony-stimulating Factor (GM-CSF)-In-Adjuvant, in Patients With High Risk Melanoma (MEL36)

Melanoma
Washington University School of Medicine

Withdrawn

Cytokine-induced Memory-like NK Cells in Combination With Chemotherapy in Pediatric Patents With Refractory or Relapsed AML

Refractory Acute Myeloid Leukemia | Relapsed Acute Myeloid Leukemia

United States
Iovance Biotherapeutics, Inc.

Active, not recruiting

Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Dana-Farber Cancer Institute
The Leukemia and Lymphoma Society

Active, not recruiting

CIML NK Cells With Venetoclax for AML

Acute Myeloid Leukemia | Leukemia | Leukemia, Myeloid | Acute Myeloid Leukemia Recurrent

United States
Radboud University Medical Center
Dutch Cancer Society

Recruiting

Natural Killer-cell Therapy for Acute Myeloid Leukemia (NK4AML)

Acute Myeloid Leukemia Refractory | Acute Myeloid Leukemia, Relapsed, Adult

Netherlands
University Hospital, Basel, Switzerland
GMP network of Basel

Completed

Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma (BaseTIL)

Advanced Melanoma

Switzerland
Hackensack Meridian Health

Terminated

In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimus (T-REG)

Graft Versus Host Disease

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Low-dose Interleukin-2 in Women With Unexplained Miscarriages (FaCIL-2)

Recurrent Miscarriage

France
Jiangsu Province Centers for Disease Control and...

Active, not recruiting

Heterologous Prime-boost Immunization With an Aerosolised Adenovirus Type-5 Vector-based COVID-19 Vaccine (Ad5-nCoV) After Priming With an Inactivated SARS-CoV-2 Vaccine

COVID-19

China
National Vaccine and Serum Institute, China
Zhengzhou University; Lanzhou Institute of Biological Products Co., Ltd; Beijing...

Active, not recruiting

A Clinical Trial to Evaluate the Recombinant SARS-CoV-2 Vaccine (CHO Cell) for COVID-19

COVID-19

China
Dana-Farber Cancer Institute

Recruiting

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Leukemia, Myeloid | Myeloproliferative Disorders | Myeloproliferative Neoplasm

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Withdrawn

Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells (CLONTAK)

CHRONIC LYMPHOCYTIC B-LEUKEMIA
Masonic Cancer Center, University of Minnesota

Completed

NK Cell Based Non-Myeloablative Transplantation in Acute Myeloid Diseases

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
Peking University People's Hospital

Unknown

Treatment of Low Dose IL-2 and Ganciclovir in Cytomegalovirus Infection

Cytomegalovirus Infections
M.D. Anderson Cancer Center

Terminated

Haploidentical Natural Killer (NK) Cells in Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma

United States
Masonic Cancer Center, University of Minnesota
Incyte Corporation

Completed

Intraperitoneal Natural Killer Cells and INCB024360 for Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

United States, Argentina, Australia, Brazil, Bulgaria, Canada, Colombia, Denmark, Estonia, Hungary, Italy, Lebanon, Malaysia, Mexico, Peru, Philippines, Poland, Romania, Russian Federation, Spain, Sweden, Taiwan
Centre Hospitalier Universitaire de Nīmes

Completed

MIROCALS: Modifying Immune Response and OutComes in ALS (MIROCALS)

Amyotrophic Lateral Sclerosis

France, United Kingdom
Masonic Cancer Center, University of Minnesota
Mayo Clinic

Completed

Decitabine and Vorinostat Conditioning Followed by CD3-/CD19- NK Cells Infusion for High Risk Myelodysplastic Syndromes

Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Completed

Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer

Metastatic Melanoma | Metastatic Kidney Cancer

United States
CAR-T (Shanghai) Biotechnology Co., Ltd.

Unknown

Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis

Knee Osteoarthritis

China
Masonic Cancer Center, University of Minnesota

Terminated

Allogeneic Natural Killer (NK) Cells in Patients With Advanced Metastatic Breast Cancer

Breast Cancer

United States
St. Jude Children's Research Hospital
CURE Childhood Cancer, Inc.

Completed

Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Neuroblastoma

United States
Instituto de Investigación Hospital Universitario...
Fundación Mutua Madrileña; Hospital Infantil Universitario Niño Jesús, Madrid...

Completed

NK Cells as Consolidation Therapy of Acute Myeloid Leukemia in Children/Adolescents

Acute Myeloid Leukemia | Leukemia | Myeloid Leukemia

Spain
Nationwide Children's Hospital

Withdrawn

Autologous Stem Cell Transplant for Refractory Crohn's Disease

Crohn's Disease
Washington University School of Medicine
Wugen, Inc.

Withdrawn

Cytokine-induced Memory-like NK Cells in Relapsed/Refractory AML and MDS

Myelodysplastic Syndromes | Refractory Acute Myeloid Leukemia | Relapsed Acute Myeloid Leukemia
M.D. Anderson Cancer Center

Terminated

Haploidentical Natural Killer (NK) Cells With Epratuzumab for Relapsed Acute Lymphoblastic Leukemia (ALL)

Leukemia | Pediatric Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute

Active, not recruiting

Lymphodepletion Plus Adoptive Cell Transfer With High Dose IL-2 in Patients With Metastatic Melanoma

Metastatic Melanoma

United States
Masonic Cancer Center, University of Minnesota

Completed

Penostatin, Rituximab and Ontak and Allogeneic Natural Killer (NK) Cells for Refractory Lymphoid Malignancies

Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma

United States
St. Jude Children's Research Hospital
Assisi Foundation

Completed

Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignancies

Non-Hodgkin's Lymphoma | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia

United States
Beni-Suef University

Recruiting

Dexmedetomidine Plus Low Dose Morphine Versus Standard Dose of Morphine in PCA in Children .

Children | Dexmedetomidine | Morphine | PCA

Egypt
Anqing Municipal Hospital

Recruiting

The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy

Dexmedetomidine Plus Esketamine Affect Postoperative Sleep Quality

China
Washington University School of Medicine
The Leukemia and Lymphoma Society; Rising Tide Foundation; St. Louis Children...

Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML (ABCD-NK)

Acute Myeloid Leukemia | Aml | AML, Childhood | Acute Myeloid Leukemia, Pediatric

United States
Washington University School of Medicine
National Cancer Institute (NCI); American Society of Clinical Oncology; ImmunityBio... and other collaborators

Terminated

Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Leukemia, Myeloid, Acute

United States
Hospital Israelita Albert Einstein

Completed

Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloproliferative Neoplasms | Myeloproliferative/Myelodysplastic Neoplasm

Brazil
Fate Therapeutics

Terminated

FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid Tumors

Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | GastroEsophageal Cancer

United States
St. Jude Children's Research Hospital

Completed

A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

Lymphoma | Neuroblastoma | High-risk Tumor

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Erythroid Leukemia | Acute Megakaryoblastic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia,... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation

Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
St. Jude Children's Research Hospital

Terminated

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Myeloid Sarcoma | Chronic Myelogenous Leukemia (CML) | Non-Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
Fred Hutchinson Cancer Center

Completed

Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma

United States
Masonic Cancer Center, University of Minnesota

Terminated

Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers.

Myelodysplastic Syndromes | Leukemia

United States
Memorial Sloan Kettering Cancer Center
Tufts Medical Center; Lahey Clinic

Completed

Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L

Multiple Myeloma

United States
National Cancer Institute (NCI)

Terminated

Gene Therapy Using Anti-Her-2 Cells to Treat Metastatic Cancer

Metastatic Cancer

United States

Search clinical trials for: CIML NK Cells plus KP1237 and low dose IL-2

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