Search clinical trials for: Calcineurin Inhibitors

Total 64335 results

University of Illinois at Chicago
Veloxis Pharmaceuticals

Completed

Converting Elderly Kidney Transplant Recipients From Tacrolimus to Envarsus to Limit Neurological AE and Improve QOL

Disorder Related to Renal Transplantation

United States
Seoul National University Hospital

Unknown

Influence of CYP3A5 Polymorphism on Liver Function Abnormality and the Trough Level Change After Conversion

Liver Dysfunction

Korea, Republic of
Astellas Pharma Europe Ltd.

Terminated

To Validate an Analytical Method to Measure Concentration of Tacrolimus in Blood Taken From Finger Pricks

Validation | Dried Blood Spot | Transplant Patients

France, United Kingdom
Centre Hospitalier Universitaire de Nice

Terminated

Maintenance Treatment of Non Segmental Vitiligo With Tacrolimus Ointment 0.1% Versus Control

Pigmentation Disorders | Vitiligo

France
Astellas Pharma Inc

Completed

Study to Evaluate the Response to Treatment and Safety of 0.03% Tacrolimus (FK506) Ointment Administered in Pediatric Patients With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

Italy
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Tacrolimus in Korean Nephropathy Patients

IgA Nephropathy

Korea, Republic of
Aurinia Pharmaceuticals Inc.

Completed

Study of ISA247 (Voclosporin) in De Novo Renal Transplantation (PROMISE)

Kidney Diseases

United States, Canada
Astellas Pharma Inc

Completed

A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy

Erectile Dysfunction | Prostate Cancer

United States
Qianfoshan Hospital

Not yet recruiting

Prognostic Model of TAC in the Treatment of MN

Idiopathic Membranous Nephropathy
University Health Network, Toronto
Paladin Labs Inc.

Not yet recruiting

Conversion of Maintenance Prograf to Envarsus in Liver Transplant Recipients

Liver Transplant Rejection | Immune System Suppression
TFF Pharmaceuticals, Inc.

Recruiting

An Open Label Trial Evaluating Tacrolimus Inhalation Powder in Adult Lung Transplant Recipients

Lung Transplant Rejection

Australia
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
University of Wisconsin, Madison
Veloxis Pharmaceuticals

Completed

Envarsus in Delayed Graft Function (E-DGF) (E-DGF)

Delayed Graft Function

United States
University Hospital, Bordeaux

Completed

Efficacy of Tacrolimus in Adults With Facial Non-segmental Vitiligo - VITAC (VITAC)

Vitiligo

France
Linical Korea
Asan Medical Center

Completed

Evaluate the Efficacy and Safety of the ADVAGRAF® (STABLE)

Evidence of Liver Transplantation

Korea, Republic of
Assistance Publique - Hôpitaux de Paris
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Unknown

Pharmacokinetic of Tacrolimus in Paediatric Liver Transplant Patients (TACTHEP)

Liver Transplantation, Child

France
Astellas Pharma Korea, Inc.

Terminated

A Study to Evaluate the Efficacy and Safety of Tacrolimus With Steroid in Korean Lupus Nephritis Patients (APPLE)

Lupus Nephritis

Korea, Republic of
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study is to Assess Efficacy and Safety of Tacrolimus in Active Rheumatoid Arthritis Patients Who Showed Unsuccessful Response to Existing Disease Modifying Antirheumatic Drugs (DMARDs) (TREASURE)

Rheumatoid Arthritis

Korea, Republic of
Peking Union Medical College Hospital

Unknown

Tacrolimus Treatment for Refractory PRCA

Pure Red Cell Aplasia

China
University of Aberdeen

Completed

Topical Tacrolimus 0.1% Ointment For Treatment Of Cutaneous Crohn's Disease

Crohn Disease

United Kingdom
Astellas Pharma Inc

Completed

An Open Study for Steroid Resistant, Non-Thymectomized MG Patients

Myasthenia Gravis

Japan
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)

Chronic GVHD

United States
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Astellas Pharma China, Inc.

Completed

A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Hanlim Pharm. Co., Ltd.

Unknown

The Study of Pharmacokinetic Interactions Between HL237 and Tacrolimus

Healthy Male Volunteers

Korea, Republic of
Auritec Pharmaceuticals
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study

Psoriasis | Organ Transplant Rejection

United States
Astellas Pharma Inc

Completed

Asian Study to Investigate Safety and Efficacy of Optimized Dosing of Advagraf in Kidney Transplantation (OPTIMIZE)

Kidney Transplantation

Taiwan, Korea, Republic of
Hannover Medical School

Terminated

Twice Daily Versus Once Daily Administration of the Tacrolimus in Lung Transplantation

Lung Transplantation

Germany
Astellas Pharma Europe Ltd.

Completed

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation (OPTION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Kim, Seoung-Hoon
Astellas Pharma Korea, Inc.; Linical Korea

Completed

To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients

Liver Transplantation
Astellas Pharma Inc

Completed

Study to Evaluate the Efficacy and Safety of 0.1% and 0.03% Tacrolimus Ointment Administered in Adults With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

Italy
Astellas Pharma Inc

Completed

Tacrolimus and Daclizumab Versus Tacrolimus and Steroids in Liver Recipients Receiving Sub-optimal Grafts (PANTERA)

LIVER TRANSPLANTATION

Italy
Astellas Pharma Inc

Completed

FK506 Phase 3 Study: a Study for Steroid Non-resistant Myasthenia Gravis (MG) Patients

Myasthenia Gravis

Japan
Astellas Pharma Inc

Completed

A Conversion Study to Assess Safety and Efficacy of a MR4 Based Immunosuppressive Regimen in Stable Liver Recipients

Transplantation

France, Spain, Germany, United Kingdom, Ireland, Poland
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

Liver Transplantation

France, Italy, Poland, Belgium, Spain, Germany, Switzerland, Canada, Finland, Brazil, Czech Republic, Australia, Norway, Sweden, United Kingdom, Ireland
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

Dose Response of Inhaled Tacrolimus in Patients With Moderate Persistent Asthma

Asthma, Bronchial | Bronchial Asthma

Russian Federation, Hungary, Germany, Poland, Bulgaria, Ukraine, Czech Republic
University of Utah
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

Heart Transplant Failure and Rejection

United States
LEO Pharma

Completed

Tacrolimus Blood Levels After Topical Application of Tacrolimus on Healthy Skin

Healthy

Germany
Linical Korea
National Cancer Center, Korea; Astellas Pharma Korea, Inc.

Completed

To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients (Assign)

Liver Transplantation
Southeast Renal Research Institute

Suspended

Safety and Efficacy of Combination Acthar Gel and Tacrolimus in the Treatment of Steroid Resistant Nephrotic Syndrome

Nephrotic Syndrome

United States
Chiesi Farmaceutici S.p.A.

Completed

Pharmacokinetic Study of ENVARSUS in Adult De-novo Kidney Transplant Patients

Organ or Tissue Transplant; Complications

France
Rennes University Hospital

Completed

Study of the Cellular Diffusion of Tacrolimus Across the Membrane of Mononuclear Cells (DIFF-TAC)

Hemochromatosis

France
Shanghai General Hospital, Shanghai Jiao Tong University...

Unknown

The Establishment of Multiple Point Prediction Model About Tacrolimus Metabolic Differences Based on Genetic Network After Liver Transplantation and the Application of Multicenter

Cirrhosis, Liver

China
Astellas Pharma Inc

Completed

Special Drug Use-Results Survey of Prograf Capsule in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Japan
Chulalongkorn University

Unknown

MicroRNA Expression in Everolimus-based Versus Tacrolimus-based Regimens in Kidney Transplantation

microRNA Profiles

Thailand
Assaf-Harofeh Medical Center

Unknown

Topical Tacrolimus 0.03% Ointment for Intractable Allergic Conjunctivitis: An Open Label Pilot Study

Allergic Conjunctivitis

Israel
Lipella Pharmaceuticals, Inc.

Not yet recruiting

Evaluating LP-10 in Subjects With OLP

Oral Lichen Planus
University Hospital, Limoges

Completed

Pharmacokinetic Study of Adoport® (Tacrolimus) in Patients With de Novo Kidney Transplantation (IMPAKT)

Transplantation | Pharmacokinetic | Kidney

France
Astellas Pharma S.A.S.

Completed

A Multicenter Study in Liver Transplant Patients Converted From Prograf® to Advagraf® During the First Post-transplantation Year (COBALT)

Liver Transplantation

France
Technical University of Munich

Completed

PEL-1235_REN-0176-I (Pelicon) (Pelicon)

Immunosuppression After Kidney Transplantation

Germany

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