Search clinical trials for: Canagliflozin 50 mg

Total 11350 results

Novartis

Completed

Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy

Type 2 Diabetes Mellitus

China
Otsuka Pharmaceutical Development & Commercialization...

Completed

Pharmacokinetic and Safety Trial to Determine the Appropriate Dose for Pediatric Patients With Multidrug Resistant Tuberculosis

Pediatric | Multidrug Resistant Tuberculosis

Philippines, South Africa
Lyndra Inc.

Terminated

Study Determining Gastric-Retentive and Modified Release Properties of Prototype Capsules in Healthy Subjects

Healthy | Gastric Retention

United Kingdom
Stendhal Americas, S.A.
LG Chem; Universidad Nacional Autonoma de Mexico

Completed

An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers

Diabetes Mellitus, Type 2

Mexico
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity

Acquired Immunodeficiency Syndrome
Reseach Laboratory of Clinical and Experimental...
Société Arabe des Industries Pharmaceutiques SAIPH - Tunisia; Centre National...

Completed

Bioequivalence Study to Compare Metformin / Vildagliptin (850 mg/50 mg) Versus Galvumet®

Fed Conditions

Tunisia
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Mercaptopurine 50 mg and Purinethol® Tablets 50 mg

Healthy

United States
Ain Shams University
Drug Research Centre, Cairo, Egypt

Completed

A Comparative Pharmacokinetic and Pharmacodynamic Study of Sildenafil in Adult Smokers and Non Smokers

Smoking | Erectile Dysfunction | Pharmacokinetics | Pharmacodynamics

Egypt
Janssen Research & Development, LLC

Terminated

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64140284 in Healthy Participants

Healthy

Belgium
AstraZeneca
Parexel; George Clinical Pty Ltd

Terminated

A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

Chronic Kidney Disease

United States, Taiwan, Germany, Hungary, Malaysia, Japan, Israel, Poland, Brazil, Ukraine, Argentina
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III; University of Navarra; Fundación para la Investigación...

Unknown

Effects of SGLT2 Inhibition on the Mechanisms of Cardiac Damage in the Diabetic Patient With HFpEF (CARDIA-STIFF)

Diabetes Mellitus, Type 2 | Heart Failure With Preserved Ejection Fraction

Spain
University of Alberta

Recruiting

The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans

Healthy

Canada
University Medical Centre Ljubljana
Chiesi Slovenija, d.o.o.

Completed

Cangrelor in Comatose Survivors of OHCA Undergoing Primary PCI (Cangrelor OHCA)

Acute Coronary Syndrome | Out-Of-Hospital Cardiac Arrest

Slovenia
University of Oxford
Oxford Brookes University; The Leona M. and Harry B. Helmsley Charitable Trust

Terminated

Dapagliflozin During Exercise for the PrevenTion of Hypoglycaemia (DEPTH)

Diabetes Mellitus, Type 1

United Kingdom
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease

Heart Failure | Kidney Diseases | Chronic Kidney Diseases | Heart Failure With Preserved Ejection Fraction

United States
Tor Biering-Sørensen

Recruiting

Effects of Dapagliflozin on EChOcardiographic Measures of CarDiac StructurE and Function in Patients With CKD (DECODE-CKD)

Chronic Kidney Diseases

Denmark
Chang Gung Memorial Hospital

Active, not recruiting

Effect of Dapagliflozin on the Recurrence of Atrial Tachyarrhythmia in Patients Undergoing Catheter Ablation of Atrial Fibrillation

Catheter Ablation | Atrial Fibrillation Recurrent

Taiwan
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Phase IIb Study of Evobrutinib in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Serbia, Ukraine, United States, Czechia, Poland, Argentina, Mexico, South Africa, Chile, Bulgaria, Colombia, Russian Federation
Cristina Mussini

Unknown

Evaluating Inflammatory and Immunological Changes of HIV-positive Patients Switching to DTG Dual Regimen Compared to Those Switching to a Triple Drugs Regimen (B/F/TAF)

HIV Infections
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Relative Bioavailability Study of a Pediatric Granule Formulation of Dolutegravir

Infections, Human Immunodeficiency Virus and Herpesviridae

United States
Damanhour University
Tanta University

Completed

Effect of Adding Vildagliptin vs Glimepiride to Metformin on Inflammation's Markers in Type-2 Diabetic Patients With CAD

Coronary Artery Disease | Diabetes Mellitus, Type 2

Egypt
Medical University of Warsaw
Medical University of Graz; Medical University of Vienna; Poznan University of... and other collaborators

Recruiting

Empagliflozin and Dapagliflozin in Patients Hospitalized for Acute Decompensated Heart Failure (EMPATHY)

Acute Decompensated Heart Failure

Poland
University Health Network, Toronto
Sunnybrook Health Sciences Centre; MOUNT SINAI HOSPITAL

Recruiting

DAPAgliflozin Sodium Water glucosE EffecTs in Patients at High Cardiovascular Risk (DAPA-SWEET)

Cardiovascular Risk Factor

Canada
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Completed

SGLT2 Inhibition in Older Obese Adults With Pre-diabetes (SGLT2i)

Aging

United States
Uppsala University
Uppsala University Hospital; Swedish Healthcare Regions; Swedish National Board... and other collaborators

Active, not recruiting

SGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 Diabetes (SMARTEST)

Type 2 Diabetes

Sweden
Saint Luke's Health System
AstraZeneca; George Clinical Pty Ltd; Saint Luke's Hospital of Kansas City

Completed

Dapagliflozin in Respiratory Failure in Patients With COVID-19 (DARE-19)

COVID-19

United States, Brazil, Argentina, India, Canada, Mexico, United Kingdom
Lawson Health Research Institute

Completed

Pleurodesis Using Hypertonic Glucose to Treat Post-operative Air Leaks (PLUG-I)

Postoperative Air Leak

Canada
AstraZeneca

Completed

A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKD

Type 2 Diabetes Mellitus, CKD and Albuminuria

United States, Spain, Canada, Korea, Republic of, Mexico, Japan, Taiwan, Australia, South Africa
University Medical Center Groningen
AstraZeneca; Dutch Kidney Foundation

Enrolling by invitation

The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD

Heart Failure | Death | Kidney Disease, Chronic | Kidney Failure | Renal Transplant Failure

Netherlands, Germany, Australia
The Netherlands Cancer Institute

Completed

Weekly Administration of (bi-)Daily Oral Docetaxel in Combination With Ritonavir

Cancer

Netherlands
Reseach Laboratory of Clinical and Experimental...
La Société Arabe des Industries Pharmaceutiques-Tunisie; Centre National Chalbi...

Completed

Bioequivalence Study to Compare Metformin / Vildagliptin Versus Galvumet®

Fed Conditions

Tunisia
Bristol-Myers Squibb

Completed

Study Investigating the Pharmacokinetic Interaction Between INX-08189 and Verapamil HCL ER in Healthy Volunteers (INX-189-005)

Healthy

United States
Adapt Produtos Oftalmológicos Ltda.

Withdrawn

Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OH

Ocular Hypertension | Open Angle Glaucoma

Brazil
Oslo University Hospital
Karolinska University Hospital; Aarhus University Hospital; Erasmus Medical Center and other collaborators

Recruiting

DAPAgliflozin for Renal Protection in Heart Transplant Recipients (DAPARHT)

Kidney Failure | Heart Transplant Failure

Netherlands, Sweden, Denmark, Norway
Mads Ersbøll

Recruiting

Dapagliflozin in Pulmonary Arterial Hypertension (DAPAH)

Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Denmark
National Heart Centre Singapore
Duke-NUS Medical School (Singapore)

Completed

Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment (DAPA-Shuttle1)

Heart Failure | Diabetes Mellitus

Singapore
AstraZeneca

Completed

Phase IV Study With a 36-week Extension Period to Evaluate the Efficacy and Safety of Dapagliflozin Therapy When Added to the Therapy of Japanese Patients With Type 2 Diabetes With Inadequate Glycemic Control on Insulin.

Type 2 Diabetes Mellitus

Japan
Jiangsu HengRui Medicine Co., Ltd.

Completed

Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes

China
ViiV Healthcare
GlaxoSmithKline

Completed

Effect of Dolutegravir on Metformin Pharmacokinetics in Healthy Adult Subjects

Infection, Human Immunodeficiency Virus

United States
Lexicon Pharmaceuticals

Completed

Study to Evaluate the Effect of Single Doses of LX4211 and Canagliflozin on Intestinal Glucose Absorption in Healthy Adult Subjects

Healthy Subjects

United States
Castagna Antonella
Bristol-Myers Squibb; ViiV Healthcare

Completed

A Study of a Nucleoside Sparing Regimen in HIV-1 Infected Patients With Detectable Viremia (Dolatav)

HIV-1 Infection

Italy
Janssen-Cilag International NV

Completed

Effects of Canagliflozin on C-peptide Clearance in Healthy Volunteers

Healthy

Germany
University of Cologne
AstraZeneca

Active, not recruiting

RICE: Radio-Immuno-Chemotherapy of Cancer of the Esophagus (RICE)

Esophageal Adenocarcinoma

Germany
Dizal Pharmaceuticals

Completed

Pharmacokinetic and Mass Balance Study of Orally Administered [14C]-AZD4205 in Healthy Adult Male Volunteers

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Completed

Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)

Glucose Intolerance
UCB Pharma SA

Completed

Comparison of Brivaracetam Oral Tablet (10 mg, 50 mg, 75 mg and 100 mg) and Brivaracetam Injection (100 mg) in Healthy Volunteers

Healthy Volunteers

Netherlands
GlaxoSmithKline

Completed

A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole

Pulmonary Disease, Chronic Obstructive

United States
Sandoz

Completed

Relative Bioavailability Study of Bicalutamide 50 mg Tablet and Casodex Following a 50 mg Dose in Healthy Subjects Under Fed Conditions

Prostate Cancer | Hirsutism
Anemia Working Group Romania
Carol Davila University of Medicine and Pharmacy; Sf Ioan Emergency Clinical... and other collaborators

Recruiting

Effect of Low Protein Diet on Top of Dapagliflozin on Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus (PRODAPA-CKD)

Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Romania
Centre Hospitalier Universitaire Saint Pierre
AstraZeneca

Terminated

Effect of the Antidiabetic Drug Dapagliflozin on the Coronary Macrovascular and Microvascular Function in Type 2 Diabetic Patients (DAPAMICRO)

Diabetes Mellitus, Type 2

Belgium

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