Search clinical trials for: Canagliflozin/Probenecid

Total 730 results

University Medical Center Groningen
AstraZeneca; Dutch Kidney Foundation

Enrolling by invitation

The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD

Heart Failure | Death | Kidney Disease, Chronic | Kidney Failure | Renal Transplant Failure

Netherlands, Germany, Australia
University Hospital Tuebingen

Withdrawn

Dapagliflozin Effect on Erythropoiesis and Physical Fitness

Type 2 Diabetes Mellitus (T2DM)

Germany
Janssen Research & Development, LLC

Completed

CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride

Diabetes Mellitus, Type 2

United States, Poland, Germany, Israel, Bulgaria, Costa Rica, India, Romania, Ukraine, Finland, Korea, Republic of, Canada, Philippines, Russian Federation, Argentina, Norway, Denmark, Slovakia, Mexico, Puerto Rico
Chinese University of Hong Kong

Recruiting

SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus

Chronic Hepatitis B

Hong Kong
Fondazione IRCCS Policlinico San Matteo di Pavia

Recruiting

Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity (PROTECT)

Breast Cancer

Italy
Anemia Working Group Romania
Carol Davila University of Medicine and Pharmacy; Sf Ioan Emergency Clinical... and other collaborators

Recruiting

Effect of Low Protein Diet on Top of Dapagliflozin on Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus (PRODAPA-CKD)

Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Romania
Medical University of Vienna
Vienna Dialysis Center

Recruiting

SGLT2 Inhibition in Hemodialysis (DAPA-HD)

Diabetes Mellitus, Type 2 | Hemodialysis | Chronic Kidney Disease | Kidney Failure | Left Ventricular Hypertrophy

Austria
Postgraduate Institute of Medical Education and...

Recruiting

Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy (DINE)

Diabetic Peripheral Neuropathy

India
Centre Hospitalier Universitaire Saint Pierre
AstraZeneca

Terminated

Effect of the Antidiabetic Drug Dapagliflozin on the Coronary Macrovascular and Microvascular Function in Type 2 Diabetic Patients (DAPAMICRO)

Diabetes Mellitus, Type 2

Belgium
Hospital Israelita Albert Einstein

Completed

Dapagliflozin in Patients With Critical Illness (DEFENDER)

Sepsis | Critical Illness

Brazil
AstraZeneca

Completed

Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo

Diabetes Mellitus

United States, Hungary, South Africa, Slovakia, Romania, Poland
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics, Pharmacodynamics, and Safety of Simvastatin in Healthy Volunteers

Healthy
Ain Shams University

Completed

Evaluation of the Effect of SGLT-2 Inhibitors on Cardiac Remodeling in Post Myocardial Infarction Patients

Myocardial Infarction | Diabetes Mellitus, Type 2 | Myocardial Remodeling, Ventricular

Egypt
University of California, San Diego
Juvenile Diabetes Research Foundation

Completed

Dapagliflozin Effects on Hypoglycemia

Type1 Diabetes Mellitus

United States
Ain Shams University

Completed

Clinical Value of Adding Dapagliflozin in Patients With Nephrotic Syndrome

Nephrotic Syndrome | Sodium-Glucose Transporter 2 Inhibitors

Egypt
University of Virginia

Recruiting

Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease (SMILE)

Myocardial Ischemia

United States
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Evaluation and Intervention of Cognitive Function in Patients With Diabetes Mellitus.

Type2 Diabetes
Cairo University

Active, not recruiting

Efficacy and Safety of Dapagliflozin in Patients With Non-alcoholic Steatohepatitis

Non-alcoholic Steatohepatitis

Egypt
Hospital de Clinicas de Porto Alegre
Vifor Pharma

Not yet recruiting

IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency (COMBINED-HF)

Heart Failure, Systolic | Iron Deficiencies

Brazil
Amsterdam UMC, location VUmc
AstraZeneca

Completed

DECREASE: Dapagliflozin Plus Exenatide on Central REgulation of Appetite in diabeteS typE 2 (DECREASE)

Obesity | Type 2 Diabetes Mellitus

Netherlands
Nidae Alaa

Recruiting

Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients

Diabetic Retinopathy

Egypt
National Institute of Diabetes and Digestive and...
Baylor University

Completed

Primary Prevention of Hypertension in Obese Adolescents

Obesity | Hyperuricemia | Pre-Hypertension

United States
University at Buffalo
Kaleida Health

Completed

An Investigation Into The Anti-hypertensive And Potential Anti-inflammatory Actions Of Dapagliflozin

Type 2 Diabetes

United States
Fondazione Schena
University of Bari

Recruiting

Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy. (CLIgAN)

Glomerulonephritis | Immunoglobulin A Nephropathy

Italy
Tan Tock Seng Hospital

Recruiting

Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes (DMVascular)

Diabetes

Singapore
University of Guadalajara

Recruiting

Effect of Dapagliflozin/Metformin XR vs Monotherapies on Anthropometric Indicators in Obesity

Obesity

Mexico
Region Örebro County
London School of Hygiene and Tropical Medicine; Odense University Hospital; Göteborg... and other collaborators

Recruiting

SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF (STENOTYPE)

Atrial Fibrillation | Chronic Coronary Syndrome

Denmark, Sweden, Czechia
Damanhour University
Menoufia University

Unknown

Value of SGLT2 Inhibitor (Dapagliflozin) as an Added Therapy in Diabetic Patients With Heart Failure With Reduced Ejection Fraction; Randomized Controlled Clinical Trial

Cardiomyopathies | Diabete Type 2 | Heart Failure With Reduced Ejection Fraction (HFrEF)
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics and Safety of an Oral Contraceptive in Healthy Volunteers

Healthy
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Fixed Dose Combination (FDC) Immediate Release (IR) Tablet of Canagliflozin and Metformin Compared to Metformin IR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Bioequivalence

United States
Assiut University

Not yet recruiting

SGLT2 Inhibitors and Perioperative Period

Perioperative Complication
State University of New York at Buffalo
Juvenile Diabetes Research Foundation; University of Glasgow

Recruiting

Triple Therapy in T1DM

Type 1 Diabetes Mellitus

United States
Cairo University
Aswan Heart Centre

Completed

Clinical Outcomes of Dapagliflozin in Acute Heart Failure With Reduced Ejection Fraction (CODA-HFrEF)

Acute Heart Failure

Egypt
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Completed

Bioequivalence of Dapagliflozin 10 mg Tablets Under Fed Conditions

Healthy Subjects

Canada
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Completed

Bioequivalence of Dapagliflozin 10 mg Tablets Under Fasting Conditions

Healthy Subjects

Canada
Fundación Pública Andaluza para la Investigación...

Unknown

SGLT-2 Inhibition, Metabolomics and Cardiovascular/Kidney Disease

Type 2 Diabetes Mellitus

Spain
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication

Type 2 Diabetes

Australia, United States, Canada, Mexico, Puerto Rico, Germany, Hungary, Ireland, Poland, Romania, Denmark, Czech Republic, India, Colombia, Finland, United Kingdom
Shanghai Zhongshan Hospital

Recruiting

Canagliflozin and Myocardial Micro-perfusion

Cardiovascular Diseases | Type 2 Diabetes | Cardiac Perfusion Defect

China
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Cyclosporine on the Pharmacokinetics and Safety of Canagliflozin (JNJ-28431754) in Healthy Volunteers

Healthy

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Iterum Therapeutics, International Limited

Completed

Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults

Complicated Urinary Tract Infections

United States, Estonia, Hungary, Georgia, Latvia
Post Graduate Institute of Medical Education and...

Not yet recruiting

MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin (SHIELD)

Non-Alcoholic Fatty Liver Disease | Hepatic Steato-Fibrosis

India
October 6 University
University of Florida; Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients

Heart Failure | Genetic Polymorphisms

United States
Hospices Civils de Lyon

Recruiting

Impact of Dapagliflozin on Intestinal Microbiota Composition and on the Metabolites Derived From the Intestinal Microbiota in Non-diabetic Chronic Renal Failure Patients (DAPA-GUT)

Chronic Kidney Diseases

France
University of Campinas, Brazil
AstraZeneca

Completed

Assessment of Dapagliflozin Effect on Diabetic Endothelial Dysfunction of Brachial Artery (ADDENDA)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Carotid Artery Diseases

Brazil
AstraZeneca
Bristol-Myers Squibb

Completed

Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients

Type 2 Diabetes

Sweden, France, Italy, Mexico, South Africa, Spain, Germany, Netherlands, Argentina, United Kingdom
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Third Affiliated Hospital... and other collaborators

Recruiting

Dapagliflozin Effect on FunctiOnal Mitral Regurgitation and Myocardial Fibrosis (DEFORM) (DEFORM)

Functional Mitral Regurgitation

China

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