Search clinical trials for: Carbonic Anhydrase Inhibitor (CAI) therapy

Total 4990 results

Sultan Qaboos University

Completed

Intravitreal Ranibizumab (Lucentis®) in the Treatment of Non-leaking Macular Cysts in Retinal Dystrophy

Retinal Dystrophies
Kahramanmaras Sutcu Imam University

Completed

Carbonic Anhydrase IX Enzyme in Triple Negative Breast Carcinoma

Triple Negative Breast Cancer | Carbonic Anhydrase IX

Turkey
Azienda Socio Sanitaria Territoriale degli Spedali...

Completed

Efficacy and Safety of Topically Applied Medical Therapy for the Treatment of Pediatric Glaucoma

Childhood Glaucoma

Italy
Tehran University of Medical Sciences

Unknown

Acetazolamide (AZ) for Management of Alkalosis in Bartter Syndrome (AZ)

Bartter Syndrome

Iran, Islamic Republic of
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Effectiveness of Acetazolamide for Reversal of Metabolic Alkalosis in Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients (DIABOLO)

Decompensated Chronic Obstructive Pulmonary Disease

France
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
Tel-Aviv Sourasky Medical Center

Unknown

Brinzolamide for the Treatment of Chronic Central Serous Chorioretinopathy

Central Serous Chorioretinopathy

Israel, Argentina
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
Sun Pharmaceutical Industries Limited

Completed

A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

India, Russian Federation
Alcon Research

Completed

Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
Bausch & Lomb Incorporated

Completed

Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt

Glaucoma | Open Angle or Ocular Hypertension

United States
Peking University First Hospital

Unknown

Efficacy Comparison of Xalatan and Azopt on POAG and OH

Ocular Hypertension
University of Illinois at Chicago

Completed

Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration

Retinal Degenerations

United States
Alcon Research

Completed

IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
University of Cologne

Completed

Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide

Control of Elevated Eye Pressure by Local and Systemic Therapy

Germany
Alcon Research
University of California, San Diego

Completed

Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Bausch & Lomb Incorporated

Completed

Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt

Glaucoma | Open Angle or Ocular Hypertension

United States
University of Arizona

Enrolling by invitation

Carbonic Anhydrase Inhibitors and Carbonation: A Novel Approach to Reduce Soda Consumption

Obesity

United States
Meiji Seika Pharma Co., Ltd.

Completed

Intrapulmonary Pharmacokinetics of ME1100 in Healthy Volunteers

Healthy

United States
Padagis LLC

Completed

To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Glaucoma, Open-Angle

United States
National Eye Institute (NEI)

Completed

Randomized Trial of Acetazolamide for Uveitis-Associated Cystoid Macular Edema

Macular Edema, Cystoid
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The AXIS Study: the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in Retinoschisis (AXIS)

Retinoschisis

Netherlands
Ziekenhuis Oost-Limburg

Completed

Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR) (Advor)

Acute Decompensated Heart Failure | Volume Overload

Belgium
University of Zurich

Completed

Chronic Clinical Effect of Acetazolamide (ChronicAZA)

Hypertension, Pulmonary

Switzerland
University of Miami

Withdrawn

Acetazolamide to Prevent Post Operative CSF Leak

Cerebrospinal Fluid Leak
Stanford University

Completed

Sickness Evaluation at Altitude With Acetazolamide at Relative Dosages (SEAWARD)

Acute Mountain Sickness

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Cerebrovascular Reserve Measurements in Sickle Cell Disease (CRUISE)

Sickle Cell Disease

Netherlands
University of Oslo School of Pharmacy

Completed

Acetazolamide for Respiratory Failure in Combination With Metabolic Alkalosis

Respiratory Insufficiency | Alkalosis

Norway
Danish Headache Center

Completed

Acetazolamide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow

Migraine | Headache

Denmark
Oxford University Clinical Research Unit, Vietnam
University of Oxford; Wellcome Trust; Mountain Medicine Society of Nepal

Completed

A Trial of Acetazolamide Versus Placebo in Preventing Mountain Sickness During Rapid Ascent

Acute Mountain Sickness

Nepal
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS); Rare Diseases... and other collaborators

Terminated

Effect of Potassium and Acetazolamide on People With Andersen-Tawil Syndrome

Andersen-Tawil Syndrome

United States
Eisai Inc.

Completed

A Safety, Tolerability and Efficacy Study of E7070 in Patients With Renal Cell Carcinoma

Kidney Neoplasms | Carcinoma, Renal Cell | Adenocarcinoma, Renal Cell

United States, France
Tehran University of Medical Sciences

Not yet recruiting

Efficacy of Oral Acetazolamide in Decongestion in Patients With Heart Failure

Heart Failure

Iran, Islamic Republic of
University of Miami

Withdrawn

Acetazolamide for the Prevention of Post Operative CSF Leak

Cerebrospinal Fluid Leak

United States
Liverpool Heart and Chest Hospital NHS Foundation...

Unknown

Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery (AZATAAR)

Thoracic Aneurysm

United Kingdom
European Organisation for Research and Treatment...

Completed

E7070 in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

France, Netherlands, Norway, Belgium, Switzerland, Austria, United Kingdom, Germany, Denmark
University Health Network, Toronto
Merck Frosst Canada Ltd.

Unknown

Ocular Blood Flow in Early Glaucoma Patients Before and After Treatment With Dorzolamide

Glaucoma

Canada
Brigham and Women's Hospital

Recruiting

Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA

OSA

United States
University of Wisconsin, Madison

Completed

Acetazolamide Challenge With Perfusion in the Prediction of Cerebral Vasospasm

Subarachnoid Hemorrhage, Aneurysmal | Vasospasm, Cerebral

United States
University of Zurich

Completed

Acute Hemodynamic Effect of Acetazolamide in Pulmonary Hypertension (AcuteAZA)

Hypertension, Pulmonary

Switzerland
NYU Langone Health

Withdrawn

A Single-center Pilot Study Evaluating the Immediate Effects of Low-dose Acetazolamide on Respiratory Control in Subjects With Treatment Emergent Sleep Disordered Breathing

Sleep Apnea

United States
US Department of Veterans Affairs

Withdrawn

Sleep Apnea: Mechanism and Cerebrovascular Consequences

Stroke | Sleep Apnea, Obstructive
Association pour la Recherche en Physiologie de...
Universidad Peruana Cayetano Heredia; University of Paris 13; Legs Poix

Completed

Treatment of High Altitude Polycythemia by Acetazolamide

High Altitude Polycythemia

Peru
Alcon Research
PPD

Terminated

1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT

Ocular Hypertension | Glaucoma

Mexico
University of Colorado, Denver
National Institute of Mental Health (NIMH); National Institute of Diabetes...

Completed

Using Learning Teams for Reflective Adaptation for Diabetes and Depression (ULTRA-DM/MDD)

Depression | Hypertension | Type 2 Diabetes | Hyperlipidemia

United States
University of California, San Diego
Juvenile Diabetes Research Foundation

Recruiting

Acetazolamide in Persons With Type 1 Diabetes

Type 1 Diabetes

United States
Uppsala University Hospital
Uppsala University; Swedish Society for Medical Research

Recruiting

Acetazolamide Trial in Normal Pressure Hydrocephalus (DRAIN)

Idiopathic Normal Pressure Hydrocephalus (INPH)

Sweden
Actavis Inc.

Completed

Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes

Glaucoma

United States
Rabin Medical Center

Unknown

Acetazolamide for Treating NPH in Shunt-candidates Patients

Normal Pressure Hydrocephalus

Israel
Eisai Limited

Terminated

An Open-label, Randomized, Phase II Study of the Efficacy and Safety of Indisulam (E7070) in Combination With Capecitabine

Metastatic Breast Cancer

Russian Federation, United Kingdom, Germany, Italy, Spain

Search clinical trials for: Carbonic Anhydrase Inhibitor (CAI) therapy

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