Search clinical trials for: Cholinergic Antagonists

Total 35643 results

Università degli Studi dell'Insubria

Completed

Topical Oestrogens and Antimuscarinics In The Treatment Of Detrusor Overactivity

Overactive Bladder

Italy
EMS

Not yet recruiting

Efficacy and Safety of CDE100 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea (ASTRAL)

Primary Dysmenorrhea

Brazil
Vanderbilt University Medical Center

Recruiting

Cholinergic Mechanisms of Attention in Aging

Subjective Cognitive Decline

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Oxybutynin Chloride ER Tablets 10 mg and Ditropan XL® Tablets 10 mg

Healthy

United States
Repurposed Therapeutics, Inc.
Defender Pharmaceuticals, Inc.

Completed

Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion

Motion Sickness

United States
Repurposed Therapeutics, Inc.

Unknown

Scopolamine in Healthy Volunteers

Major Depressive Disorder (MDD)

United States
University of South Florida
Merck Sharp & Dohme LLC

Completed

Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency

Neuromuscular Blockade
American University of Beirut Medical Center

Completed

"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"

Anesthesia Recovery

Lebanon
CHU de Reims
Verathon

Completed

Curarisation and Intubation Conditions During Videolaryngoscopy With Glidescope Titanium (GICAC)

Tracheal Intubation

France
Massachusetts General Hospital

Terminated

A Study of the Use of IV Scopolamine to Augment the Efficacy of Electroconvulsive Therapy (ECT)

Depression

United States
Seoul National University Hospital

Unknown

The Effects of Preoperative Scopolamine Patch Application on the Postoperative Nausea and Vomiting in MVD Surgery

Patients
Universitaire Ziekenhuizen KU Leuven

Completed

Whole-body Diffusion MRI for Staging, Response Prediction and Detecting Tumor Recurrence in Patients With Ovarian Cancer (S53580)

Ovarian Carcinoma

Belgium
Astellas Pharma Europe B.V.

Completed

Long Term Study of Solifenacin Succinate and Tamsulosin Hydrochloride Oral Controlled Absorption System (OCAS) in Males With Lower Urinary Tract Symptoms (Neptune II)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

Belgium, Italy, France, Austria, United Kingdom, Netherlands, Poland, Slovakia, Belarus, Germany, Czechia
Medical Corps, Israel Defense Force

Unknown

Motion Sickness Medications and Vestibular Time Constant

Drug Reaction

Israel
Mansoura University

Recruiting

Mirabegron, Propevirine, Solifenacin for Treatment of Lower Urinary Tract Symptoms During Intravesical BCG Instillation

Voiding Disorders

Egypt
Dartmouth-Hitchcock Medical Center

Recruiting

Nebulizer Delivery of Intranasal Scopolamine

Motion Sickness | Scopolamine

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Oxybutynin Chloride ER Tablets 10 mg and Ditropan XL® Tablets 10 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Oxybutynin Chloride Extended-release Tablets 10 mg and Ditropan XL® Tablets 10 mg

Healthy

United States
National Taiwan University Hospital

Completed

Comparisons of the Effects of Solifenacin Versus Mirabegron on Autonomic System, Arterial Stiffness and Psychosomatic Distress and Clinical Outcomes

Overactive Bladder Syndrome

Taiwan
Memorial Sloan Kettering Cancer Center

Completed

Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant

Surgery

United States
LENZ Therapeutics, Inc

Completed

A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia

Presbyopia

United States
Dong-A ST Co., Ltd.

Completed

A Therapeutic Exploratory Clinical Study of DA-8010 in Patients With Overactive Bladder

Overactive Bladder

Korea, Republic of
Novartis Pharmaceuticals

Completed

Prospective Cohort Study for the Real - Life Effectiveness Evaluation of GlycOpyrronium With IndacatERol Combination in the Management of COPD in Canada (POWER Study) (POWER)

Chronic Obstructive Pulmonary Disease

Canada
University of California, San Francisco

Completed

Treatment of Incontinence Without Memory Problems (TRIUMPH)

Urge Incontinence | Urinary Incontinence, Urge

United States
Astellas Pharma Inc

Completed

Single-dose Study to Assess Pharmacokinetics of Solifenacin Succinate Suspension in Children and Adolescents

Urinary Bladder, Overactive

Sweden, United Kingdom, Belgium, Denmark
Novartis Pharmaceuticals

Withdrawn

Safety and Efficacy of NVA237 as an add-on to Fixed Dose Combination LABA/ICS (GLOW8)

Chronic Obstructive Pulmonary Disease
Boehringer Ingelheim

Completed

Determine the Bioequivalence of Two Formulations of Hyoscine Butylbromide.

Healthy

Canada
James J. Peters Veterans Affairs Medical Center

Completed

Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCI

Neurogenic Bowel | Spinal Cord Injury

United States
Astellas Pharma Europe B.V.

Completed

Study to Test the Efficacy and Safety of YM178 in Subjects With Symptoms of Overactive Bladder (Blossom)

Urinary Bladder, Overactive

Belgium, Czech Republic, Germany, Spain, Sweden, United Kingdom
NeuroHealing Pharmaceuticals Inc.
Michael J. Fox Foundation for Parkinson's Research

Completed

Safety and Efficacy Study of NH004 Films for Relief of Sialorrhea Symptoms in Parkinson's Disease Patients (NH004-2)

Sialorrhea Secondary to Parkinson's Disease

Argentina
St. Antonius Hospital

Completed

Peri -and Postoperative Drug Therapy Schedules for Morbidly Obese Patients (POP-II)

Obese | Morphine | Nadroparin | Cefazolin | Atracurium

Netherlands
FemmePharma Global Healthcare, Inc.

Completed

A Study of Oxybutynin for the Treatment of Urge Urinary Incontinence (FP1097-002)

Urinary Incontinence, Urge

United States
The Second Affiliated Hospital of Chongqing Medical...
Chongqing Medical University; First Affiliated Hospital of Chongqing Medical... and other collaborators

Completed

Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting

China
Drexel University
Merck Sharp & Dohme LLC

Completed

Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Nausea | Vomiting

United States
Prisma Health-Upstate

Completed

Wearing-Off Period of Pharmacological Dilation and Anisocoria

Anisocoria

United States
University of Maryland, Baltimore

Withdrawn

Effects of Prazosin on the Attention-Enhancing Effects of Nicotine

no Condition, Basic Science
Brigham and Women's Hospital

Recruiting

Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy

Obstructive Sleep Apnea

United States
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

Enhanced Recovery After Surgery for Anterior Cervcial Spine Surgeries in Elderly Patients

Other Fusion of Spine, Cervical Region
Ono Pharmaceutical Co. Ltd

Completed

Study of ONO-8577 in Patients With Overactive Bladder

Overactive Bladder

Japan
Northern Sydney Anaesthesia Research Institute
Merck Sharp & Dohme LLC; Northern Sydney and Central Coast Area Health Service

Terminated

Prevention of Postoperative Events Following Reversal With Sugammadex or Neostigmine (P-PERSON)

Pulmonary Complications

Australia
Vanderbilt University Medical Center

Withdrawn

Autonomic Blockade and Endogenous Glucose Production

Insulin Resistance

United States
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC

Completed

Sugammadex vs. Neostigmine for Neuromuscular Blockade Reversal in Thoracic Surgical Patients

Neuromuscular Blockade

United States
Repurposed Therapeutics, Inc.

Unknown

Nasal Gel Under Military Operational Conditions for the Prevention of Nausea Associated With Motion Sickness

Motion Sickness

United States
Repurposed Therapeutics, Inc.

Completed

Nasal Gel for the Prevention and Treatment of Nausea Associated With Motion Sickness

Motion Sickness

United States
Merck Sharp & Dohme LLC

Completed

Study of Sugammadex Versus Usual Care on Incidence of Residual Blockade at Post Anesthesia Care Unit Admission (P07981)

Surgical Procedures, Elective
Astellas Pharma Inc

Completed

A Clinical Study to Assess the Effect on Pharmacokinetics of Dosing Mirabegron (YM178) and Solifenacin Simultaneously

Healthy Volunteers | Pharmacokinetics of Mirabegron

France
Allergan

Completed

Trospium Chloride XR in Obese Female Patients With Overactive Bladder

Obesity | Overactive Bladder | Incontinence

United States
University Hospital, Ghent

Completed

Echocardiographic Study of the Haemodynamic Effects of Remifentanil With and Without Glycopyrrolate in Healthy Children

Urological Surgery

Belgium

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