Search clinical trials for: Cholinergic Antagonists

Total 35763 results

Charite University, Berlin, Germany

Completed

A Study to Assess and Compare the Effects of 5 mg vs. 20 mg Desloratadine on the Development of Cold Urticaria Lesions (AUDACU)

Acquired Cold Urticaria

Germany
Warner Chilcott

Terminated

A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity

Neurogenic Detrusor Overactivity

United States, Colombia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Effect of Detrol LA on Overactive Bladder Symptoms, Sexual Quality of Life and Sexual Function in Women

Urinary Incontinence

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Evaluate Efficacy and Safety Of Tolterodine Extended Release Capsule Compared With Tolterodine Immediate Release Tablet

Urinary Incontinence

China
Pfizer's Upjohn has merged with Mylan to form Viatris...
Pfizer

Completed

Study to Determine The Effectiveness Of Detrusitol In Patients Diagnosed With OAB

Urinary Incontinence
Novartis Pharmaceuticals

Completed

Comparing the Pharmacokinetics, Safety and Tolerability of NVA237 in Renal Impairment

Renal Impairment

Russian Federation
Ottawa Hospital Research Institute

Unknown

Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease (GLYCOPAR)

Parkinson's Disease | Sialorrhea

Canada
University of Pennsylvania
Pfizer

Completed

Validation of Instruments for Pragmatic Clinical Trials for Overactive Bladder (PfizerOABLUT)

Overactive Bladder

United States
Gulhane Training and Research Hospital

Recruiting

Association of Anticholinergic Burden With Onset of Delirium in Older Adults With Alzheimer Dementia:

Delirium | Alzheimer Disease | Anticholinergic Adverse Reaction

Turkey
Ottawa Hospital Research Institute

Completed

Anticholinergic Risk Scale and Resource Use After Elective Noncardiac Surgery

Aged | Length of Stay | Epidemiology | Surgical Procedure, Operative | Anti Cholinergics

Canada
Jeil Pharmaceutical Co., Ltd.

Completed

The PK Study of the JLP-1207 and Solifenacin/Tamsulosin in Healthy Male Volunteers.

Overactive Bladder | Benign Prostatic Hyperplasia | LUTS(Lower Urinary Tract Symptoms)
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the Intestine, Distributed Through the Body and Eliminated From the Body When Administered in Combination as a Single Tablet (Called EC905)

Healthy Subjects | Pharmacokinetics | EC905 | Multiple Dose

United Kingdom
National Taiwan University Hospital

Not yet recruiting

Association With Low Compliance Bladder in Women With LUTS

Urinary Bladder, Overactive | Urinary Incontinence | Pelvic Organ Prolapse | Urinary Bladder Neck Obstruction

Taiwan
GlaxoSmithKline

Completed

A 12-week Study to Evaluate the Efficacy and Safety of Umeclidinium 62.5 Microgram (mcg) Compared With Glycopyrronium 44 mcg in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Argentina, Germany, Romania, Russian Federation, Chile, Sweden, Spain, Hungary, Czechia, Norway
Universidad de Valparaiso
Recalcine (GynoPharm)

Completed

Efficacy of Darifenacin and Physiotherapy for the Treatment of Overactive Bladder in Women

Overactive Bladder

Chile
Advanced Research Network
Astellas Pharma US, Inc.

Terminated

VESIcare For Improving OAB Symptoms in Patients Undergoing IGRT of the Prostate

Over-Active Bladder

United States
Astellas Pharma Inc

Completed

A Multicenter VESIcare® Efficacy and Safety Study for the Treatment of Urgency Associated With Overactive Bladder (OAB) (VENUS)

Urinary Bladder, Overactive

United States
Hospital Israelita Albert Einstein

Completed

Long Term Results of the Use of Oxybutynin for the Treatment of Hyperhidrosis

Hyperhidrosis

Brazil
Astellas Pharma Inc

Completed

Study of VESIcare® In Overactive Bladder (OAB) Subjects to Evaluate Symptom Bother and Health Related Quality of Life (VIBRANT)

Urinary Bladder, Overactive

United States
Zhuan Zhang

Recruiting

Effect of Perioperative Use of Glycopyrrolate on Lung Function in Patients Under General Anesthesia

Glycopyrrolate

China
Weill Medical College of Cornell University
Pfizer

Completed

An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia (Toviaz)

Bladder Outlet Obstruction

United States
Astellas Pharma Inc

Completed

Open-label Study of the Efficacy and Safety of VESIcare® in Patients With Overactive Bladder Symptoms (VOLT)

Urinary Bladder, Overactive

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (GLOW7)

Chronic Obstructive Pulmonary Disease (COPD)

China, Philippines, Korea, Republic of, India
Pfizer

Completed

The Effect Of Fesoterodine On Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects

Urinary Bladder, Overactive

United States
Pfizer

Terminated

Multiple Dose Study To Investigate The Effects Of Fesoterodine And Solifenacin On Gastrointestinal Transit

Healthy

United States
University of South Florida

Completed

Solifenacin Succinate (VESIcare) for the Treatment of Overactive Bladder in Parkinson's Disease (URGE-PD)

Overactive Bladder in Parkinson's Disease

United States
Astellas Pharma Inc

Completed

A Study to Assess Efficacy and Safety With Solifenacin Succinate to Improve Urinary Continence After Robotic Assisted Radical Prostatectomy

Urinary Incontinence

United States, Canada
Guang'anmen Hospital of China Academy of Chinese...
Beijing Hospital; Capital Medical University

Unknown

Treatment, Parallel Assignment, Double Blind (Subject, Outcomes Assessor), Efficacy Study

Overactive Bladder

China
Astellas Pharma Inc

Completed

Efficacy & Safety Study of VESIcare® (Solifenacin Succinate) in Patients Wishing to Switch From Detrol LA® for Treatment of Overactive Bladder (VERSUS)

Urinary Bladder, Overactive

United States
National Taiwan University Hospital

Completed

Studies of Psychiatric Predisposing Factors, Treatment-related Cardiovascular Effects, and Prognostic Factors Associated With Antimuscarinic Drug (Tolterodine) for Female Overactive Bladder Syndrome

Antimuscarinic Drug

Taiwan
Astellas Pharma Inc

Completed

Solifenacin as Add-on Therapy for Overactive Bladder Symptoms in Men Treated for Benign Prostatic Hyperplasia

Overactive Bladder | Benign Prostatic Hyperplasia | Benign Prostatic Hypertrophy

Japan
University of Victoria

Recruiting

Role of Desloratadine in Reducing Inflammation From Occupational Heat Strain

Inflammatory Response | Heat Stress, Exertional | Firefighter Personal Protective Equipment

Canada
Organon and Co

Completed

A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147) (ATTITUD)

Urticaria | Chronic Idiopathic Urticaria
Organon and Co

Completed

A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine 10 MG Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03735)

Urticaria
Organon and Co

Completed

Multi-center, Pediatric, Open-label, Preference Study of Desloratadine 2.5 mg Reditab (SCH34117) and Zyrtec 5.0 mg Chewable Tablet Medications (Study P04574)(COMPLETED)

Allergies
Organon and Co

Completed

The Effect of Desloratadine and Levocetirizine on Nasal Obstruction (Study P03609)

Allergic Rhinitis
Peking Union Medical College Hospital
Astellas Pharma China, Inc.; Beijing CAT Science Co., Ltd.

Completed

Effectiveness and Safety Study of Solifenacin Succinate and Solifenacin Succinate + Estrogen to Treat OAB in Postmenopausal Women (OAB)

Overactive Bladder | Urination Disorders | Postmenopausal Disorder

China
Jie Chen

Enrolling by invitation

Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic Polypectomy

Colonoscopy | Glycopyrrolate

China
Journey Medical Corporation

Completed

A Study of Glycopyrronium Cloth, 2.4% in Patients With Palmar Hyperhidrosis

Palmar Hyperhidrosis

United States
Merck Sharp & Dohme LLC

Completed

A Study to Test the Effects of Tolterodine Tartrate in Patients With Overactive Bladder (0000-107)

Overactive Bladder
Novartis Pharmaceuticals

Completed

NVA237 BID Versus Placebo Twelve-week Efficacy Study

Chronic Obstructive Pulmonary Disease

United States
University Hospital, Brest
Ministry of Health, France

Completed

Treatment of Hyperhidrosis With Oxybutynin (H²O)

Hyperhidrosis

France
Shionogi

Completed

Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic Conditions

Cerebral Palsy | Sialorrhea | Mental Retardation | Neurological Conditions

United States
KK Women's and Children's Hospital

Withdrawn

Does Undercorrection of Myopia Retard Myopia Progression Among Kindergarten Children?

Refractive Error - Myopia
Alza Corporation, DE, USA

Completed

Efficacy and Safety of OROS Oybutynin and TTS Oxybutynin in Middle-Aged and Elderly Women With Urinary Incontinence

Urinary Incontinence
Soonchunhyang University Hospital

Completed

The Efficacy of Solifenacin With or Without Tamsulosin in Adult Women With Overactive Bladder (OAB)

Overactive Bladder

Korea, Republic of
Astellas Pharma Inc

Completed

A Study to Evaluate Solifenacin Succinate in Combination With Tamsulosin for the Treatment of Residual Overactive Bladder Symptoms (OAB) in Men. (VICTOR)

Urinary Incontinence

United States
Astellas Pharma Taiwan, Inc.

Completed

Study to Evaluate the Clinical Efficacy and Safety of Tamsulosin Alone or in Combination With Solifenacin for the Treatment in Men With Lower Urinary Tract Symptoms Including Overactive Bladder Symptoms

Overactive Bladder | Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia (BPH)

Taiwan
Boehringer Ingelheim

Completed

Spiolto® Respimat® (Tiotropium/Olodaterol) Versus Triple Combination Therapy in Everyday Clinical Treatment Practice for Chronic Obstructive Pulmonary Disease (EVELUT®)

Pulmonary Disease, Chronic Obstructive

Germany
KYU-SUNG LEE
Pfizer

Completed

Exploring Predictors of Symptoms Relapse After Discontinuation of Treatment in Overactive Bladder (OAB) Patients

Overactive Bladder

Korea, Republic of

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