Search clinical trials for: Cilengitide EMD 121974

Total 1853 results

National Cancer Institute (NCI)

Completed

Cilengitide (EMD 121974) in Treating Patients With Advanced Solid Tumors or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Terminated

Cilengitide in Treating Patients With Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia Without Maturation (M1) | Adult Acute Myeloid Leukemia With 11q23 (MLL)... and other conditions

United States
EMD Serono

Completed

Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor)

Glioblastoma Multiforme

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Patients With Prostate Cancer

Recurrent Prostate Cancer | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
National Cancer Institute (NCI)

Terminated

Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Neoplasm | Adult Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

EMD 121974 in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy

Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent Childhood Anaplastic Oligoastrocytoma | Recurrent Childhood Anaplastic Oligodendroglioma | Recurrent Childhood Cerebellar Astrocytoma | Recurrent Childhood... and other conditions

United States, Canada
National Cancer Institute (NCI)

Terminated

Cilengitide in Treating Patients With Unresectable or Metastatic Melanoma

Stage IV Melanoma | Stage III Melanoma

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Patients With Metastatic Prostate Cancer

Recurrent Prostate Cancer | Stage IV Prostate Cancer

United States
National Cancer Institute (NCI)

Terminated

Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Bart Neyns

Terminated

Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastoma

Glioblastoma

Belgium
Centre Oscar Lambret

Completed

Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma (CILENT-0902)

Diffuse Intrinsic Pontine Glioma

France
National Cancer Institute (NCI)

Completed

Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Neoplasm

United States
Martin-Luther-Universität Halle-Wittenberg
Merck KGaA, Darmstadt, Germany

Terminated

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents (HGG-CilMetro)

Gliomas

Germany
National Cancer Institute (NCI)

Completed

Weekly Doses of Cilengitide and Paclitaxel in Treating Patients With Advanced Solid Tumors That Cannot Be Removed by Surgery

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Adult Solid Neoplasm

United States
M.D. Anderson Cancer Center
EMD Serono; Brain Tumor Trials Collaborative

Withdrawn

Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)

Glioblastoma
National Cancer Institute (NCI)

Completed

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Merck KGaA, Darmstadt, Germany

Completed

Pharmacokinetics in Subjects With Renal Impairment

Renal Impairment

Germany
Tioga Pharmaceuticals
RTI Health Solutions

Completed

Asimadoline for the Treatment of Subjects With Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

EMD 121974 in Treating Patients With Progressive or Recurrent Glioma

Brain and Central Nervous System Tumors

United States
Tioga Pharmaceuticals

Completed

A Metabolite Identification, Mass Balance, and PK Study of [14C]-Asimadoline to Healthy Adult Male Volunteers

Healthy

United States
Matthias Löhr

Completed

Autologous Cell Sheets Transplantation After ESD in the Esophagus (CellSheet2)

Barrett Esophagus

Sweden
Indiana University School of Medicine
National Cancer Institute (NCI)

Completed

EMD 121974 in Treating Patients With Locally Advanced or Metastatic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
National Cancer Institute (NCI)

Terminated

EMD 121974 in Treating Patients With HIV-Related Kaposi's Sarcoma

Sarcoma

United States
Tioga Pharmaceuticals
RTI Health Solutions

Completed

Study of Asimadoline to Treat Diarrhea-Predominant Irritable Bowel Syndrome (D-IBS)

Diarrhea Predominant Irritable Bowel Syndrome

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Catharina... and other collaborators

Not yet recruiting

EMR Versus ESD for Barrett's Neoplasia (REMOVE-RCT)

Esophageal Cancer | Barrett Adenocarcinoma | Barretts Esophagus With Dysplasia
Universitätsmedizin Mannheim
Heidelberg University

Completed

Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer (CIRAB)

Lung Cancer | Brain and Central Nervous System Tumors

Germany
Chestnut Health Systems
National Institute on Drug Abuse (NIDA)

Completed

Using Smartphones to Provide Recovery Support Services (SRSS)

Recovery | Substance Use Disorder (SUD)

United States
Chinese University of Hong Kong

Not yet recruiting

Clinical Outcomes After EMR or ESD of Colorectal Neoplasms - A Multicenter Registry

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma

Hong Kong
Institut Claudius Regaud
Merck KGaA, Darmstadt, Germany

Completed

Cilengitide Together With Radiochemotherapy in Patients With Locally Advanced Non Small Cell Lung Cancer

Locally Advanced Non Small Cell Lung Cancer (NSCLC)

France
Tioga Pharmaceuticals
RTI Health Solutions

Terminated

Asimadoline for the Treatment of Post-Operative Ileus

Post-Operative Ileus

United States
UMC Utrecht
Comprehensive Cancer Centre The Netherlands

Unknown

EMR Versus ESD for Resection of Large Distal Non-pedunculated Colorectal Adenomas (MATILDA)

Colorectal Neoplasms

Netherlands
EMD Serono
Merck KGaA, Darmstadt, Germany

Completed

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status (CORE)

Glioblastoma

United States, Germany
Assistance Publique - Hôpitaux de Paris

Terminated

Impact of an Electronic Monitoring Device on Maintaining a Correct Elevation of Head of Bed for Mechanically-ventilated Patients in Intensive Care Unit (Inclinometre2)

Mechanically-ventilated Patients

France
Nanfang Hospital of Southern Medical University

Unknown

Endoscopic Treatment of Rectal Neuroendocrine Tumor(NET) Less Than 10mm

Rectal Neuroendocrine Tumor
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection (BEEPER)

Barrett Esophagus | Barrett Adenocarcinoma | Esophagus Neoplasm

United States, Germany
Arafat Tfayli
Merck KGaA, Darmstadt, Germany; Phoenix Clinical Research

Unknown

Neoadjuvant Compound 121564 Plus Platinum Doublet Chemotherapy in Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer Stage

Lebanon, Jordan
Ohio State University
University of Campinas, Brazil

Completed

Furcation Therapy With Enamel Matrix Derivative

Chronic Periodontitis
Connecticut Children's Medical Center

Completed

Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma

Asthma

United States
EMD Serono

Terminated

First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors

Solid Tumors

United States
Temple University
Albert Einstein Healthcare Network; Eunice Kennedy Shriver National Institute... and other collaborators

Recruiting

Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

Spinal Cord Injuries

United States
EspeRare Foundation

Completed

Rimeporide in Patients With Duchenne Muscular Dystrophy (RIM4DMD)

Muscular Dystrophy, Duchenne

Italy, France, Spain, United Kingdom
Semmelweis University

Completed

Treatment of Periodontal Intrabony Defects With A-PRF+ or EMD

Periodontal Diseases

Hungary
Hacer Sahin Aydinyurt
Yuzuncu Yıl University

Completed

A Novel Volumetric Analysis Using CAD/CAM Scanners in Gingival Recession Treatment

Gingival Recession
Western Sydney Local Health District

Recruiting

ESD for Colorectal LSL Using a Selective Strategy - a Prospective Cohort Study (COVERT)

Colorectal Neoplasm | Endoscopic Mucosal Resection

Australia
University of Pisa
Institut Straumann AG

Completed

Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy (PERIOEMD-2)

Periodontal Diseases

Italy
University Hospital, Limoges

Active, not recruiting

Endoscopic Submucosal Dissection (ESD) Versus Endoscopic Mucosal Resection (EMR) for Large Non Pedunculated Colonic Adenomas: a Randomized Comparative Trial (RESECT COLON)

Colonic Polyp

France
Universidad Complutense de Madrid

Recruiting

Emdogain Adjunctive to Autotransplantation (ATTEMD)

Autologous Transplantation | Emdogain | Autotransplantation | Enamel Matrix Derivatives

Spain
Baylor College of Medicine

Active, not recruiting

Monopolar Current Cutting Knife vs Bipolar RFA Knife

Gastrointestinal Neoplasms

United States

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