Search clinical trials for: Comparator Drug (non-biologic IL-17 inhibitors)

Total 9032 results

Bausch Health Americas, Inc.

Enrolling by invitation

LTS of Siliq vs. Other Therapies Treating of Adults With Moderate-to-Severe Psoriasis

Psoriasis

United States
Aswan University Hospital

Unknown

17-Alpha-Hydroxyprogesterone Caproate in Pregnant Women With Placenta Previa

Placenta Previa

Egypt
Centre Hospitalier Universitaire de Nīmes

Recruiting

Optimizing Anti-IL17 Antibody Therapy by Associating Fiber Supplementation to Correct Treatment-aggravated Gut Dysbiosis in Axial Spondyloarthritis - RESPOND-IL17 (RESPOND-IL17)

Axial Spondyloarthritis

France
Hoffmann-La Roche

Completed

Retrospective Analysis of Pulmonary Arterial Hypertension (PAH) and Related Complications in Juvenile Idiopathic Arthritis (JIA) Participants Treated With Biologic and Non-biologic Disease-modifying Anti-rheumatic Drugs (DMARDs)

Juvenile Idiopathic Arthritis
Janssen Biotech, Inc.

Completed

Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database

Psoriasis
Merck Sharp & Dohme LLC

Completed

A Study of V503 Given Concomitantly With Menactra™ and Adacel™ in 11 to 15 Year Olds (V503-005)

Human Papillomavirus Infection
Genexine, Inc.

Completed

Clinical Trial of GX-I7 in Healthy Volunteers

Healthy

Korea, Republic of
Janssen Biotech, Inc.

Completed

Golimumab Safety and Surveillance Program Using the Ingenix NHI Database

Rheumatoid Arthritis | Arthritis, Psoriatic | Ankylosing Spondylitis
Merck Sharp & Dohme LLC

Completed

A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014)

Advanced Breast Cancer | Other Solid Tumors
Merck Sharp & Dohme LLC

Completed

MK0524A Phase IIb Study (0524A-011)(COMPLETED)

Flushing
Merck Sharp & Dohme LLC

Completed

Concomitant Use of Gardasil (V501) (Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diphtheria, Tetanus, Pertussis Vaccine and Meningococcal Conjugate Vaccine in Adolescents (V501-025)

Neoplasms, Glandular and Epithelial | Whooping Cough | Tetanus | Diphtheria | Meningitis
Merck Sharp & Dohme LLC

Completed

A Study of the Effect of Estrogen on Estrogen Receptor Biomarkers in Healthy Postmenopausal Women (0000-094)(COMPLETED)

Postmenopause
Centre Hospitalier Universitaire de Besancon

Recruiting

Biomedicines and Bacterial Translocation in Spondyloarthritis (TEARE-BIO)

Axial Spondyloarthritis

France
Clinical Nutrition Research Center, Illinois Institute...
Tomato Products Wellness Council

Completed

A Study of Tomato Products and Disease Risk (TOM)

Inflammation

United States
Biocad

Completed

First-in-human Study to Evaluate Safety, Tolerability and Pharmacokinetics of Various Doses of BCD-085 in Healthy Subjects

Healthy
Biocad

Completed

First-in-human Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Various Doses of BCD-121 in Healthy Subjects

Healthy
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Inflammatory Bowel Disease | Ankylosing Spondylitis
Iovance Biotherapeutics, Inc.

Active, not recruiting

Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Seqirus

Completed

Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of QIVc in Subjects ≥2 to <18 Years of Age

Influenza, Human

Australia, Estonia, Finland, Lithuania, Philippines, Poland, Spain, Thailand
Organon and Co

Completed

Rheumatoid Arthritis Dose Ranging Study (0663-086)(COMPLETED)

Rheumatoid Arthritis
Merck Sharp & Dohme LLC

Completed

Biomarkers of Muscle Anabolism (MK-0000-082)

Muscle Anabolism
Organon and Co

Completed

A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)

Postoperative Dental Pain
Merck Sharp & Dohme LLC

Completed

Safety and Tolerability of MK0773 in Healthy Older Men (0773-004)

Healthy
Merck Sharp & Dohme LLC

Completed

A Clinical Study to Evaluate the Effects of Estrogen in Healthy Postmenopausal Women

Postmenopausal Symptoms
Organon and Co

Completed

An Investigational Drug Study in the Treatment of Primary Dysmenorrhea (0663-064)

Dysmenorrhea
Antibe Therapeutics Inc.
Veristat, Inc.

Completed

Efficacy and Safety of ATB-346 Versus Placebo in Osteoarthritis Patients

Osteoarthritis

Canada
Organon and Co

Completed

To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 mg (0653-079)(COMPLETED)

Hypercholesterolemia
University Hospital Dubrava
Ministry of Science, Education and Sport, Republic of Croatia

Unknown

Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer

Colonic Neoplasms

Croatia
Novartis Pharmaceuticals

Terminated

A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers

Metastatic and Advanced Solid Tumors

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED)

Primary Hypercholesterolemia | Mixed Hyperlipidemia
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effect of Testosterone on Muscle Fractional Synthetic Rate (MK-0000-064)

Muscle Anabolism
Aswan University Hospital

Unknown

Aspirin for Prevention of Preeclampsia

Preeclampsia

Egypt
Denise Mafra

Completed

Effects of Curcumin in Patients in Chronic Kidney Disease

Chronic Kidney Diseases

Brazil
Oregon Health and Science University
Eli Lilly and Company

Completed

Ixekizumab in the Treatment of Pityriasis Rubra Pilaris (PRP)

Pityriasis Rubra Pilaris

United States
Aswan University Hospital

Unknown

Vaginal Progesterone Versus 17-Alpha-Hydroxyprogesterone Caproate in Placenta Previa

Placenta Previa

Egypt
Almirall, S.A.

Active, not recruiting

Observational Real-world Evidence (RWE) Study to Assess Patient-reported Wellbeing Using Tildrakizumab in Live Setting - POSITIVE Study (POSITIVE)

Plaque Psoriasis

Germany
University of Arizona

Enrolling by invitation

Pain Management Study

Pain, Postoperative

United States
Organon and Co

Completed

A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)

Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (MK0431-023)

Diabetes Mellitus, Type 2
Organon and Co

Completed

To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)

Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

Sitagliptin and Pioglitazone Mechanism of Action Study in Type 2 Diabetes Mellitus (0431-061)

Type 2 Diabetes Mellitus (T2DM)
Organon and Co

Completed

Study of the Bioequivalence of the 20% and 30% Etoricoxib Tablet Formulations (0663-070)

Pain
Aswan University Hospital

Completed

Dexmedetomidine Versus Clonidine for Transversus Abdominis Plane Block in Patients Undergoing Elective Caesarean Section

Postoperative Pain

Egypt
Second Affiliated Hospital of Soochow University

Recruiting

Hypofractionated Radiotherapy Combined With PD-1 Inhibitor Sequential GM-CSF and IL-2 for the Treatment of Advanced Refractory Solid Tumors (PRaG2.0)

Advanced Refractory Solid Tumors

China
Gregory Daniels

Recruiting

High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma

Melanoma Stage Iv | Renal Cell Carcinoma, Metastatic

United States
Organon and Co

Completed

A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-077)(COMPLETED)

Osteoarthritis
Aswan University Hospital

Completed

Lidocaine Spray Plus Oral Celecoxib for Pain Control During Hysterosalpingography

IUCD Complication

Egypt
University of Alabama at Birmingham
Patient-Centered Outcomes Research Institute

Recruiting

RA-PRO PRAGMATIC TRIAL (RA-PROPR)

Rheumatoid Arthritis

United States, Canada
Seqirus

Completed

Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an MF59-Adjuvanted Quadrivalent Influenza Vaccine Compared to Non-influenza Vaccine Comparator in Adults ≥ 65 Years of Age

Influenza

Turkey, Philippines, Thailand, Malaysia, Lithuania, Colombia, Czechia, Estonia, Bulgaria, Latvia, Poland, Romania
The Methodist Hospital Research Institute
Genentech, Inc.

Terminated

Safety Study of Specific Tumor Target Drug Plus Immune System Therapy in Patients With Kidney Cancer

Carcinoma, Renal Cell

United States

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