Search clinical trials for: Comparator: MK0752, Notch Inhibitor - 3 days on, 4 off

Total 813 results

Makerere University
Mbarara University of Science and Technology; Ministry of Health, Uganda; Joint...

Not yet recruiting

Safety & Efficacy of Low Dose Aspirin / Ivermectin Combination Therapy for Treatment of Covid-19 Patients (IVCOM)

Covid19
Assistance Publique - Hôpitaux de Paris

Terminated

Predictive Biomarkers of Response to Sunitinib in the Treatment of Poorly-differentiated NEURO-Endocrine Tumors (NET)

Pancreatic Neoplasms | Neuroendocrine Tumors | Advanced Disease | Sunitinib

France
Boehringer Ingelheim

Completed

An Open Label Trial of Afatinib (Giotrif) in Treatment-naive (1st Line) or Chemotherapy Pre-treated Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring EGFR Mutation(s)

Carcinoma, Non-Small-Cell Lung

Spain, Israel, Italy, Austria, Czechia, Greece, Australia, Poland, Hungary, Portugal, Russian Federation
GlaxoSmithKline

Completed

A Phase II Study Evaluating Intranasal GSK256066 and Fluticasone Propionate in Subjects With Seasonal Allergic Rhinitis (SAR)

Rhinitis, Allergic, Seasonal

Austria
Merck Sharp & Dohme LLC

Completed

An Investigational Drug for the Prevention of Chemotherapy-Induced Nausea and Vomiting (MK-0869-071)

Breast Neoplasms | Nausea | Vomiting
Merck Sharp & Dohme LLC

Completed

MK-0524B Lipid Study (MK-0524B-063)

Mixed Dyslipidemia | Primary Hypercholesterolemia
Pfizer

Completed

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

HEALTHY

China
Oxford University Hospitals NHS Trust

Completed

RF Power, LSI and Oesophageal Temperature Alerts During AF Ablation (PiLOT-AF Study) (PiLOT-AF)

Atrial Fibrillation

United Kingdom
National Cancer Institute (NCI)

Completed

Gamma-Secretase Inhibitor RO4929097 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

Canada
Sanofi
Kowa Company, Ltd.

Completed

TOFO Insulin Combination Trial

Type 2 Diabetes Mellitus

Japan
University of Iowa

Completed

A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department

Uncomplicated Bacterial Cystitis

United States
Marius Aliuskevicius
University of Aarhus

Completed

Non Steroidal Antiinflammatory Drugs Influence on Heal of Distal Radius Fracture (CHIP)

Forearm Fracture

Denmark
Centre Hospitalier Universitaire de Liege

Completed

A Before and After Study Studying the Impact of an Analgesia Protocol After Discharge From Outpatient Surgery

Postoperative Pain | Outpatient Surgery

Belgium
Merck Sharp & Dohme LLC

Terminated

An Investigational Drug Study to Assess Weight Loss in Patients With Type 2 Diabetes Mellitus (0364-011)(TERMINATED)

Type 2 Diabetes Mellitus | Obesity Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Terminated

A Weight Maintenance Study in Obese Patients (0364-012)(TERMINATED)

Obesity
Merck Sharp & Dohme LLC

Completed

Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)

Pain, Postoperative Arthroscopy
Organon and Co

Completed

Study Evaluating the Efficacy and Safety of Simvastatin Alone Compared With Simvastatin Plus Ezetimibe in Type 2 Diabetic Patients (0653-021)(COMPLETED)

Diabetes Mellitus, Type 2
Masonic Cancer Center, University of Minnesota

Active, not recruiting

MT2017-45: CAR-T Cell Therapy for Heme Malignancies

Acute Lymphoblastic Leukemia | Large B-cell Lymphoma

United States
Weill Medical College of Cornell University

Terminated

Effects of Electronic Cigarettes on Lung Biology

Lung Disease | Lung Disorder

United States
AstraZeneca
Quintiles, Inc.

Completed

A Study to Investigate the Potential for AZD5672 to Affect the Electrical Conduction Pathways in the Heart

Rheumatoid Arthritis

United Kingdom
Diagram B.V.

Completed

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent (REDUCE)

Acute Coronary Syndrome
Singapore General Hospital

Completed

Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic Ulcers

Bleeding Peptic Ulcers Disease

Singapore
M.D. Anderson Cancer Center
Access Pharmaceuticals, Inc.

Completed

4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies

Leukemia

United States
Rush University Medical Center

Completed

Aprepitant- and Olanzapine- Containing Anti-emetic Regimens With High Dose Melphalan

Nausea | Vomiting

United States
Constellation Pharmaceuticals

Completed

A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas

B-Cell Lymphoma

United States
AstraZeneca

Completed

Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin

Healthy Volunteers | Pharmacokinetics

United Kingdom
Merck Sharp & Dohme LLC

Terminated

A Two Year Safety and Efficacy Study in Obese Patients (0364-015)(TERMINATED)

Obesity
Zhejiang Cancer Hospital
Fudan University; Cancer Institute and Hospital, Chinese Academy of Medical... and other collaborators

Completed

Recombinant Human Endostatin Continued Pumping Into Vein Combining With CCRT in Unresectable Stage III NSCLC

Stage III Non-small-Cell Lung Cancer

China
Lexicon Pharmaceuticals

Completed

Study to Evaluate Sotagliflozin in Subjects With Varying Degrees of Renal Function

Healthy | Renal Impairment

United States
Massachusetts General Hospital
Boehringer Ingelheim; Incyte Corporation

Recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Cholangiocarcinoma | Advanced Solid Tumor | Metastatic Solid Tumor | Unresectable Solid Tumor

United States
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Completed

Low Dose Daily Erlotinib in Combination With High Dose Twice Weekly Erlotinib in Patients With EGFR-Mutant Lung Cancer

EGFR-Mutant Lung Cancer

United States
Kanazawa University
Kowa Company, Ltd.

Completed

SGLT2 Inhibitor Versus Sulfonylurea on Type 2 Diabetes With NAFLD

Non-alcoholic Fatty Liver Disease

Japan
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma

United States
Spanish Clinical Pharmacology Society
Spanish reumatology Society

Completed

Evaluation of a Protocol for Dose Reduction in Patients With Spondylarthropathies and Clinical Remission With Anti-TNF (REDES-TNF)

Spondylarthropathies

Spain
Pennington Biomedical Research Center
Louisiana Clinical and Translational Science Center

Completed

Safety and Pharmacokinetics of an Extract of Naringenin (Citrus)

Pharmacokinetics | Safety Issues

United States
University of California, San Diego

Suspended

A Study of Haploidentical Bone Marrow Transplant for Patients With Hematologic Malignancies

Hematologic Malignancies

United States
Tehran University of Medical Sciences

Completed

A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome

Coronary Artery Disease | Metabolic Syndrome

Iran, Islamic Republic of
Kyowa Kirin, Inc.

Completed

Study of KW-0761 Versus Vorinostat in Relapsed/Refractory CTCL

Cutaneous T-Cell Lymphoma

United States, Spain, France, Australia, Switzerland, United Kingdom, Japan, Denmark, Germany, Italy, Netherlands
GlaxoSmithKline

Completed

A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis

Allergic Rhinitis | Rhinitis, Allergic, Seasonal

Austria
ANRS, Emerging Infectious Diseases
INSERM SC10-US19

Recruiting

Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load (SYNACTHIV)

HIV-1-infection, Subtype b

Belgium, France
Eisai Inc.

Completed

Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid Tumors

Ewing Sarcoma | Rhabdomyosarcoma | Refractory or Recurrent Solid Tumors | Non-Rhabdomyosarcoma Soft Tissue Sarcoma

Spain, United Kingdom, Italy, France, Germany, Greece, Poland, Switzerland
AM-Pharma

Completed

Recombinant Human Alkaline Phosphatase in Healthy Japanese Subjects

Healthy

Japan
Sanofi

Terminated

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Diet and Exercise

Type 2 Diabetes Mellitus

China
Jiuda Zhao
Second Hospital of Lanzhou University

Recruiting

A Study to Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer

Gastric Cancer | Chemotherapy | Immunotherapy

China
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm

United States
Jonsson Comprehensive Cancer Center
BeiGene; Driven To Cure

Withdrawn

Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer

Metastatic Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Unresectable Renal Cell Carcinoma | Hereditary Leiomyomatosis and Renal Cell Carcinoma | Clear Cell Papillary Renal Neoplasm | Hereditary Papillary Renal Cell Carcinoma and other conditions

United States
Edda Spiekerkoetter
Stanford University

Completed

FK506 (Tacrolimus) in Pulmonary Arterial Hypertension (TransformPAH)

Pulmonary Arterial Hypertension

United States
University of California, San Francisco
BeiGene USA, Inc.; Pacific Pediatric Neuro-Oncology Consortium

Recruiting

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas (PNOC017)

Glioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | Low Grade Glioma | Recurrent WHO Grade II Glioma | WHO Grade II Glioma

United States
Genuine Research Center, Egypt
Future Pharmaceuticals Industries, Egypt

Completed

Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)

Healthy

Egypt
AstraZeneca

Completed

Drug Interaction Study - Effect of AZD5672 on the Pharmacokinetics of Digoxin

Healthy Volunteers | Pharmacokinetics

Germany

Search clinical trials for: Comparator: MK0752, Notch Inhibitor - 3 days on, 4 off

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