Search clinical trials for: Control (bradykinin)

Total 64949 results

Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3

Obesity

United States
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Remote Ischaemic Preconditioning in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University Hospital, Grenoble
University Hospital, Rouen; University Hospital, Paris

Recruiting

Bradykinin-degradating Enzymes Activities in Angiotensin-Converting Enzyme Inhibitors-associated Angioedema (KIN-ACE)

Angio-Oedema Caused by Angiotensin-Converting-Enzyme Inhibitor

France
Vanderbilt University Medical Center
Renal Research Institute; Pharvaris Netherlands B.V.

Recruiting

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor

Intradialytic Hypotension

United States
Laboratoire Innotech International
ITEC Services

Completed

Contraceptive Efficacy, Tolerance and Acceptability of a Benzalkonium Chloride Spermicide Cream In Women Aged Over 40 Years of Age (BZK40+)

Contraception

France, Russian Federation
Vanderbilt University

Terminated

Tissue-Type Plasminogen Activator (t-PA) Release Predicts Major Adverse Cardiac Events (MACE) in Patients With Non-critical Coronary Artery Disease

Coronary Artery Disease

United States
Heidelberg University

Unknown

Vasoreactivity in Carriers of Genetic Polymorphisms

Healthy

Germany
Shire

Completed

A Study of Icatibant in Patients With Acute Attacks of Hereditary Angioedema (FAST-3)

Hereditary Angioedema

United States, Australia, Israel, Canada, Hungary, Romania, Russian Federation, South Africa, Ukraine
Shire

Completed

A Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angioedema

Hereditary Angioedema (HAE)

United States, Canada, Australia, Austria, Colombia, Germany, Hungary, Israel, Italy, Spain
Sanofi

Completed

Efficacy and Safety Study of Intra-articular Multiple Doses of Icatibant in Patients With Painful Knee Osteoarthritis

Joint Disease

United States, Austria, Czech Republic, Germany, Poland
Takeda

Completed

A Study of Icatibant (TAK-667) in Japanese Children and Teenagers With Acute Attacks of Hereditary Angioedema

Hereditary Angioedema

Japan
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Bradykinin Receptor Blocker in ACE Inhibitor-associated Angioedema

Angioneurotic Edema

United States
Shire

Completed

A Study of Icatibant for Acute Attacks of Hereditary Angioedema in Japanese Participants

Hereditary Angioedema (HAE)

Japan
Massachusetts General Hospital
Shire Human Genetic Therapies, Inc.

Completed

Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE (IHA)

Hereditary Angioedema

United States
Bernstein, Jonathan A., M.D.
Dyax Corp.

Unknown

Evaluation of Ecallantide for the Acute Treatment of Angiotensin Converting Enzyme Inhibitor Induced Angioedema (ACE)

Angioedema

United States
Shire
Jerini AG

Completed

EASSI - Evaluation of the Safety of Self-Administration With Icatibant (EASSI)

Hereditary Angioedema

Spain, Argentina, Austria, Denmark, France, Germany, Israel, Italy, Switzerland, United Kingdom
Shire
Takeda

Completed

FIRAZYR General Drug Use-Results Survey (Japan)

Hereditary Angioedema (HAE)

Japan
Shire
PPD

Completed

Blinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor Induced Angioedema

Angiotensin Converting Enzyme Inhibitor Induced Angioedema

United States, Canada, United Kingdom, Israel
Takeda

Recruiting

A Survey of Icatibant in Pediatric Participants With Hereditary Angioedema

Hereditary Angioedema (HAE)

Japan
Shire

Completed

Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers

Hereditary Angioedema (HAE)

United States
Vanderbilt University Medical Center

Completed

Mitochondria and Chronic Kidney Disease (MitoCKD)

Mitochondrial Diseases | Hemodialysis-Induced Symptom

United States
Vanderbilt University Medical Center
Shire

Terminated

Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema

ACE Inhibitor-associated Angioedema

United States
Menarini Group

Completed

Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee (ALBATROSS-3)

Knee Osteoarthritis

United States, Italy, Germany, Czech Republic
Vanderbilt University

Completed

Bradykinin Receptor Antagonism During Cardiopulmonary Bypass (BRAC)

Inflammation | Surgery | Cardiopulmonary Bypass | Fibrinolysis

United States
Shire

Completed

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema

Angioedema

United States
Belfast Health and Social Care Trust
Queen's University, Belfast

Completed

Inhibition of Bradykinin in COVID-19 Infection With Icatibant (ICASARS)

SARS CoV 2 Infection

United Kingdom
GCS Ramsay Santé pour l'Enseignement et la Recherche

Completed

Evaluation of the Effects of Bradykinin Antagonists on Pulmonary Manifestations of COVID-19 Infections (AntagoBrad-Cov Study). (AntagoBrad)

Covid19

France
Sebastian Videla

Completed

Investigating the Efficacy and Safety ICATIBANT For The Treatment of Patients With SARS-CoV-2 (COVID-19) Infection (ICAT·COVID)

COVID-19 Pneumonia

Spain
Technical University of Munich

Completed

AMelioration of Angiotensin Converting Enzyme Inhibitor Induced Angioedema Study

Angioedema

Germany
Vanderbilt University

Withdrawn

Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients (P1A4D)

Heart Transplantation

United States
Vanderbilt University

Terminated

Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation (P1A3B)

Obesity

United States
Vanderbilt University

Withdrawn

Brachial Artery t-PA Release in Heart Transplant Recipients (P1A3C)

Heart Transplantation

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Miconazole on Blood Flow

Healthy

United States
Shire

Completed

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE) (FAST2)

Hereditary Angioedema

Italy
Menarini Group

Completed

A Locally Injected Bradykinin Antagonist for TReatment of OSteoarthritiS (ALBATROSS)

Osteoarthritis, Knee

Germany, France, Italy, Spain
Medice Arzneimittel Pütter GmbH & Co KG
University Hospital Muenster

Completed

Safety and Efficacy of a Sore Throat Lozenge DORITHRICIN in Patients With Acute Pharyngitis (DoriPha)

Pharyngitis

Germany
Vanderbilt University Medical Center

Recruiting

Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 2

Heart Failure

United States
Vanderbilt University

Completed

Pharmacogenetics of Ace Inhibitor-Associated Angioedema

Hypertension | Diabetes Type 2

United States
Nantes University Hospital

Terminated

Register and DNA Bank of Adult Extra-hospital Sudden Death (Protocol FASTER)

Extra-hospital Sudden Death

France
Jeanette Du

Not yet recruiting

Low Dose Atropine for Symptomatic Vitreous Floaters

Vitreous Floaters

United States
Vanderbilt University Medical Center

Withdrawn

Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure NYHA Class I

United States
GlaxoSmithKline

Completed

A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive

Denture Retention

United States
Charite University, Berlin, Germany
Freie Universität Berlin

Unknown

Cognitive Training to Improve Cognitive Function Following Chemotherapy (KT)

Cognitive Dysfunction

Germany
Florida State University

Recruiting

Central Executive Training (CET) for ADHD

ADHD

United States
Postgraduate Institute of Medical Education and...

Completed

Closed Loop Isoflurane Administration With Bispectral Index in Open Heart Surgery

Open Heart Surgery

India
Yonsei University

Completed

The Effect of Pressure Controlled Ventilation on the Pulmonary Mechanics in Prone Position Using the Wilson Frame: A Comparison With Volume Controlled Ventilation

Herniation of Lumbar Vertebral Disc

Korea, Republic of
Stefan Soderberg
University of Edinburgh

Completed

Leptin Infusion and Endothelial Vasomotor Response (LIVARM)

Obesity | Endothelial Dysfunction | Vasodilation | Venous Occlusion Plethysmography

Sweden, United Kingdom
Inje University

Recruiting

Effect of Remimazolam on Postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting

Korea, Republic of
Federico II University

Completed

Fiber-enriched Croissant Consumption and Effects on Metabolic Status, Appetite and Gut Microbiota (CROMA)

Healthy | Overweight and Obesity

Italy

Search clinical trials for: Control (bradykinin)

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